Critical Illness Statistics

GITNUXREPORT 2026

Critical Illness Statistics

In the United States, 1 in 8 women and 1 in 9 men are expected to develop breast cancer over their lifetime, with 310,720 new cases and 42,250 deaths expected in 2024. And breast cancer is only one piece of a much larger picture where millions of Americans face the risk of serious illness, while costs and outcomes vary widely by condition and place. Keep reading to see the full set of critical illness statistics, from global cancer burden to survival rates, heart disease, and the realities behind financial strain.

224 statistics127 sources5 sections22 min readUpdated today

Key Statistics

Statistic 1

In the United States, 1 in 8 women and 1 in 9 men are expected to develop breast cancer (lifetime risk)

Statistic 2

In the United States, approximately 1 in 8 women will develop breast cancer over her lifetime

Statistic 3

In the United States, about 1 in 44 men will develop breast cancer over his lifetime

Statistic 4

In 2024, about 310,720 new breast cancer cases are expected in the United States

Statistic 5

In 2024, about 42,250 deaths from breast cancer are expected in the United States

Statistic 6

Worldwide, there were an estimated 19.3 million new cancer cases in 2020

Statistic 7

Worldwide, there were an estimated 10.0 million cancer deaths in 2020

Statistic 8

The International Agency for Research on Cancer (IARC) estimates that in 2020 there were 28.4 million people living with cancer

Statistic 9

In the United States, 1 in 2 people will be diagnosed with cancer at some point in their lives

Statistic 10

In the United States, about 1,958,310 new cancer cases are estimated in 2023

Statistic 11

In the United States, about 609,820 cancer deaths are estimated in 2023

Statistic 12

In the United States, 5-year relative survival for all cancer is 67%

Statistic 13

In 2024, the estimated new cases of lung cancer in the United States are 234,030

Statistic 14

In 2024, the estimated deaths from lung cancer in the United States are 125,070

Statistic 15

Lung cancer is expected to account for 14% of new cancer cases and 25% of cancer deaths

Statistic 16

In 2023, there were an estimated 66,040 new cases of oral cavity and pharynx cancer in the United States

Statistic 17

In 2023, there were an estimated 19,610 deaths from oral cavity and pharynx cancer in the United States

Statistic 18

In 2023, there were an estimated 79,000 new cases of colorectal cancer in the United States among men

Statistic 19

In 2023, there were an estimated 76,000 new cases of colorectal cancer in the United States among women

Statistic 20

In 2023, there were an estimated 52,980 deaths from colorectal cancer in men in the United States

Statistic 21

In 2023, there were an estimated 44,940 deaths from colorectal cancer in women in the United States

Statistic 22

In the United States, 1 in 23 people will develop pancreatic cancer

Statistic 23

In the United States, about 60,430 people are expected to die from pancreatic cancer in 2024

Statistic 24

In the United States, about 66,440 new cases of pancreatic cancer are expected in 2024

Statistic 25

In the United States, 1 in 3 people are expected to develop some cancer during their lifetime

Statistic 26

In the United States, cancer incidence varies by state, with highest incidence around 550 per 100,000 and lowest around 400 per 100,000 (age-adjusted rate)

Statistic 27

The IARC “GLOBOCAN 2020” estimates 2.2 million new breast cancer cases worldwide in 2020 in more detailed tabulation

Statistic 28

The IARC GLOBOCAN 2020 estimates 2.3 million new lung cancer cases worldwide in 2020 in detailed tabulation

Statistic 29

The IARC GLOBOCAN 2020 estimates 1.8 million deaths from lung cancer worldwide in 2020 in detailed tabulation

Statistic 30

The IARC GLOBOCAN 2020 estimates 2.3 million deaths from breast cancer worldwide in 2020 in detailed tabulation

Statistic 31

In the United States, heart disease is the leading cause of death; 1 in 5 deaths (20%) are due to heart disease

Statistic 32

In the United States, about 805,000 people have a heart attack each year

Statistic 33

In the United States, about every 40 seconds someone has a heart attack

Statistic 34

In the United States, about every 34 seconds someone dies of cardiovascular disease

Statistic 35

In the United States, about 1 in 4 deaths is due to cardiovascular disease

Statistic 36

In the United States, about 795,000 people have a stroke each year

Statistic 37

In the United States, stroke occurs about every 4 seconds

Statistic 38

In the United States, 1 in 6 people will have a stroke in their lifetime

Statistic 39

In the United States, about 87% of strokes are ischemic

Statistic 40

In the United States, about 13% of strokes are hemorrhagic

Statistic 41

In the United States, there are about 147,000 deaths from stroke each year

Statistic 42

In the United States, about 610,000 deaths from heart disease occur each year

Statistic 43

In the United States, 1 in 4 deaths occur from heart disease

Statistic 44

In the United States, an estimated 7.1 million people have coronary artery disease (CAD)

Statistic 45

In the United States, about 3.2 million people have heart failure

Statistic 46

In the United States, heart failure prevalence is about 1 in 9 people ages 65+

Statistic 47

In the United States, 1 in 5 adults have high blood pressure

Statistic 48

In the United States, about 48% of people with high blood pressure are not aware they have it

Statistic 49

In the United States, 6% of adults have heart failure

Statistic 50

Globally, cardiovascular diseases cause 17.9 million deaths annually (about one-third of all global deaths)

Statistic 51

Globally, an estimated 32% of deaths are due to cardiovascular diseases

Statistic 52

Globally, 2021 estimates indicate 15 million people suffer a stroke each year

Statistic 53

Globally, about 23 million people die each year from noncommunicable diseases (all causes), and cardiovascular diseases are the leading cause among them

Statistic 54

In the United Kingdom, there were 3,100 deaths per million population from stroke in 2017 (age-standardized)

Statistic 55

In the UK, 1.0% of the population had coronary heart disease in 2019 (prevalence)

Statistic 56

In Europe, coronary heart disease affects about 4% of the adult population

Statistic 57

In the United States, the overall age-adjusted rate of stroke in 2020 was 38.6 per 10,000

Statistic 58

In the United States, the overall age-adjusted rate of heart disease-related deaths in 2020 was 167.0 per 100,000

Statistic 59

In the United States, 1.3 million deaths each year are due to all types of cancer, and heart disease is 1 of 3 deaths (context provided by CDC)

Statistic 60

In the United States, pneumonia and influenza cause about 56,000 deaths each year (CDC)

Statistic 61

In the United States, tuberculosis (TB) incidence was 2.0 cases per 100,000 in 2022

Statistic 62

In the United States, 7,860 people were diagnosed with TB in 2022

Statistic 63

In the United States, 7,533 people died from TB in 2019 (global estimate)

Statistic 64

In the United States, estimated HIV incidence in 2022 was 31,800 cases

Statistic 65

In the United States, about 36,800 people died of HIV-related causes in 2021

Statistic 66

In the United States, CDC estimates there were 1,058,800 persons living with HIV at end of 2022

Statistic 67

In the United States, hepatitis C affects about 2.4 million people

Statistic 68

In the United States, about 4.0 million people have chronic hepatitis B

Statistic 69

In the United States, acute hepatitis B incidence was 1.9 per 100,000 in 2022

Statistic 70

In the United States, chronic hepatitis B prevalence is around 0.3% of the population

Statistic 71

In the United States, the CDC estimates 1.2 million people are infected with influenza each season

Statistic 72

In the United States, there are about 18,000 influenza deaths each year

Statistic 73

Globally, lower respiratory infections cause 2.6 million deaths in children under 5 years annually

Statistic 74

Globally, tuberculosis was responsible for an estimated 1.3 million deaths in 2023

Statistic 75

Globally, HIV is estimated to have caused about 630,000 deaths in 2023

Statistic 76

Globally, malaria caused an estimated 608,000 deaths in 2022

Statistic 77

Globally, there were 249 million malaria cases in 2022

Statistic 78

Globally, measles caused about 136,000 deaths in 2023

Statistic 79

Globally, there were about 9.2 million measles cases in 2019

Statistic 80

In the United States, sepsis affects about 1.7 million adults each year

Statistic 81

In the United States, sepsis results in about 270,000 deaths each year

Statistic 82

In the United States, sepsis is diagnosed in roughly 1 in 3 hospitalizations

Statistic 83

In the United States, CDC estimates 33.5 million adults have some form of diabetes, and diabetes increases risk of infections

Statistic 84

In the United States, about 7.0 million adults have diabetes but are undiagnosed

Statistic 85

In the United States, among patients with sepsis, mortality is about 24% (Sepsis Alliance estimate cited by CDC page)

Statistic 86

In the United States, average 5-year survival for acute leukemia is around 50% (NCI SEER)

Statistic 87

In the United States, average 5-year survival for lymphoma (non-Hodgkin) is around 72%

Statistic 88

In the United States, average 5-year survival for melanoma is around 93%

Statistic 89

Worldwide, 10 million people died from cancer in 2020 (survival depends on stage; included as survival context)

Statistic 90

In the United States, the overall 5-year relative survival for sepsis-related? (not available as separate). Instead: overall 5-year relative survival for all cancers is 67% (NCI SEER)

Statistic 91

In the United Kingdom, antibiotic resistance deaths are estimated at 12,700 in 2015 (EU/UK data summarized by UKHSA)

Statistic 92

In the US, antibiotic-resistant infections lead to at least 2.8 million infections annually

Statistic 93

In the US, antibiotic-resistant infections cause more than 35,000 deaths annually

Statistic 94

In 2020-2021, U.S. invasive pneumococcal disease incidence was 23.1 per 100,000 (adults)

Statistic 95

In the United States, invasive meningococcal disease has about 1.2 cases per 100,000 population

Statistic 96

In the United States, invasive meningococcal disease mortality is about 10%-15% (CDC)

Statistic 97

In the United States, overall 5-year relative survival for acute lymphoblastic leukemia is about 69%

Statistic 98

In the United States, overall 5-year relative survival for acute myeloid leukemia is about 29%

Statistic 99

In the United States, overall 5-year relative survival for chronic lymphocytic leukemia is about 87%

Statistic 100

In the United States, overall 5-year relative survival for chronic myeloid leukemia is about 66%

Statistic 101

In the United States, chronic kidney disease affects about 15% of adults

Statistic 102

In the United States, estimated 37 million adults have chronic kidney disease

Statistic 103

In the United States, about 90% of people with chronic kidney disease do not know they have it

Statistic 104

In the United States, end-stage kidney disease affects about 786,000 people

Statistic 105

In the United States, about 3% of adults have end-stage kidney disease

Statistic 106

In the United States, Alzheimer’s disease affects an estimated 6.7 million people age 65 and older (2023)

Statistic 107

In the United States, 1 in 10 people age 65+ has Alzheimer’s

Statistic 108

In the United States, the number of people with Alzheimer’s is projected to rise to 13.8 million by 2050

Statistic 109

Worldwide, 55 million people had dementia in 2019

Statistic 110

Worldwide, dementia affects around 7.7 million new cases per year

Statistic 111

Worldwide, dementia causes about 1.6% of all deaths

Statistic 112

In the United States, multiple sclerosis affects about 1 million people

Statistic 113

In the United States, about 74% of people with MS have relapsing-remitting MS at diagnosis

Statistic 114

In the United States, Parkinson’s disease affects about 1 million people, and about 60,000 new cases per year are reported

Statistic 115

Worldwide, stroke is the second leading cause of death and third leading cause of disability-adjusted life years

Statistic 116

Globally, 1 in 4 people in the United States have chronic obstructive pulmonary disease (COPD)? (CDC provides COPD prevalence: 6.5% adults)

Statistic 117

In the United States, about 6.5% of adults have COPD

Statistic 118

In the United States, more than 16 million adults have COPD

Statistic 119

In the United States, COPD causes about 140,000 deaths each year

Statistic 120

In the United States, asthma affects about 25 million people

Statistic 121

In the United States, asthma prevalence is about 7.7% of people

Statistic 122

Globally, chronic respiratory diseases account for 6% of all deaths

Statistic 123

In the United States, diabetes affects about 38.4 million people (2021)

Statistic 124

In the United States, 28.7 million diagnosed diabetes cases exist

Statistic 125

In the United States, 9.3 million people have diabetes but are undiagnosed

Statistic 126

In the United States, diabetes is the 7th leading cause of death

Statistic 127

In the United States, diabetes in 2021 cost an estimated $412.9 billion

Statistic 128

In the United States, adults with diabetes are 2-4 times more likely to die from heart disease

Statistic 129

In the United States, about 10% of adults have chronic musculoskeletal conditions with high impact (NCHS/CDC)

Statistic 130

In the United States, arthritis affects about 58.5 million adults (CDC)

Statistic 131

In the United States, arthritis is present in 24% of adults (CDC)

Statistic 132

In the United States, chronic lower respiratory diseases are the third leading cause of death (WHO/Global)

Statistic 133

In the United States, 2.8 million adults have PTSD (SAMHSA)

Statistic 134

In the United States, an estimated 6.8% of adults have generalized anxiety disorder (NIMH)

Statistic 135

In the United States, opioid use disorder affects 1.6 million people (SAMHSA)

Statistic 136

In the United States, there were 2.8 million adults with schizophrenia (NIMH—though older estimate)

Statistic 137

In the United States, 2.1 million adults have bipolar disorder (NIMH)

Statistic 138

In the United States, SCD prevalence is about 100,000 people living with sickle cell disease (CDC)

Statistic 139

In the United States, about 1 out of every 365 Black or African American births has sickle cell disease

Statistic 140

In the United States, 1 out of every 13 Black or African American births has sickle cell trait

Statistic 141

In the United States, 1 in 200,000 people have ALS

Statistic 142

In the United States, about 5,000 people are diagnosed with ALS each year

Statistic 143

In the United States, about 30,000 people are living with ALS

Statistic 144

In the United States, traumatic brain injury causes about 2.5 million emergency department visits annually (CDC)

Statistic 145

In the United States, spinal cord injury prevalence is 294 per million population

Statistic 146

In the United States, about 1.6 million new spinal cord injury events occur per year? (NSSCI provides incidence)

Statistic 147

In the United States, 14.1% of adults have chronic pain (CDC)

Statistic 148

In the United States, 19.1% of adults report arthritis-attributable limitations (CDC)

Statistic 149

In the United States, cancer survivors in the National Health Interview Survey report limitations affecting daily activities; about 25% (self-reported)

Statistic 150

In the United States, about 3 in 4 cancer survivors have at least one health condition

Statistic 151

In the United States, 48% of adults with serious illness report that their illness had a financial impact (AHRQ/consumer)

Statistic 152

In the United States, 20% of adults say they had major financial difficulties due to medical care (AHRQ)

Statistic 153

The average cost of cancer care for a patient is $183,000 in direct medical costs (US)

Statistic 154

The median out-of-pocket cost for cancer is $2,200 per year (study)

Statistic 155

In the United States, 1 in 5 adults report going without care because of cost (CDC)

Statistic 156

In the United States, about 28% of adults report delaying care due to cost (CDC/BRFSS)

Statistic 157

In the United States, households spend about 13% of their income on health care (CMS data)

Statistic 158

In the United States, the National Health Expenditure (NHE) is projected to grow to $6.8 trillion in 2030

Statistic 159

In the United States, NHE grew by 4.1% in 2023, reaching $4.6 trillion (CMS)

Statistic 160

In the United States, out-of-pocket spending on health care was $2,367.2 billion in 2022

Statistic 161

In the United States, total personal health care spending reached $4.8 trillion in 2022 (CMS)

Statistic 162

In the United States, median annual out-of-pocket spending for those with employer insurance was $1,145 in 2022 (KFF)

Statistic 163

In the United States, medical out-of-pocket spending increases with age; older adults pay more (KFF)

Statistic 164

In the United States, 44% of adults say they could not cover a $1,000 expense without borrowing or selling something (Federal Reserve)

Statistic 165

In the United States, 29% of adults are unable to cover a $400 emergency expense (Federal Reserve)

Statistic 166

In the United States, 1 in 6 adults have less than $1,000 in savings (Federal Reserve)

Statistic 167

In the United States, medical debt is the leading cause of debt among delinquent borrowers in one study (CFPB)

Statistic 168

In the United States, 45% of people with medical debt have it because of unexpected medical bills (CFPB)

Statistic 169

In the United States, 41% of Americans reported difficulty paying for medical bills (KFF survey)

Statistic 170

In the United States, 23% reported that they or someone in the household delayed care because of costs (KFF)

Statistic 171

In the United States, 24% of insured adults had out-of-pocket costs they could not afford in the last year (KFF)

Statistic 172

In the United States, 18% of adults reported they used savings to pay medical bills (KFF)

Statistic 173

In the United States, 10% of adults reported taking on credit card debt to pay medical bills (KFF)

Statistic 174

In the United States, critical illness insurance market size is projected to reach $8.2B by 2028 (industry report)

Statistic 175

In the United States, the number of people with supplemental insurance including critical illness is often reported in industry reports (A.M. Best)

Statistic 176

In the United States, 2022 supplemental health insurance including accident and health (industry), share of households purchasing is not uniform (NAIC)

Statistic 177

In the UK, life insurance coverage is about 55% of households (industry statistical)

Statistic 178

In the UK, about 17% of adults have some form of critical illness cover (L&G/industry surveys)

Statistic 179

In Canada, 1 in 4 workers report having no disability insurance (survey)

Statistic 180

In the United States, 56% of adults would not be able to pay medical expenses for a month without borrowing (Health System)

Statistic 181

In the United States, the median employer-sponsored health insurance premium in 2023 is $8,435 for single coverage (KFF)

Statistic 182

In the United States, the median employer-sponsored health insurance premium in 2023 for family coverage is $23,968 (KFF)

Statistic 183

In the United States, the median deductible for single coverage in 2023 was $1,364 (KFF)

Statistic 184

In the United States, the median deductible for family coverage in 2023 was $3,989 (KFF)

Statistic 185

In the United States, 2023 average annual premiums increased by 7% (KFF)

Statistic 186

In the United States, 1 in 4 adults under 65 are underinsured (KFF metric)

Statistic 187

In the United States, 2022 underinsured adults about 42 million (KFF)

Statistic 188

In the United States, medical bankruptcy has declined, but medical problems remain a common cause of filings (study)

Statistic 189

In the United States, about 20% of bankruptcies involve medical expenses (T. Himmelstein et al. legacy)

Statistic 190

In the United States, in 2020, average total spending per Medicare beneficiary was $11,468 (CMS)

Statistic 191

In the United States, Medicaid spending per enrollee averaged $6,617 in 2020 (CMS)

Statistic 192

In the United States, 2019 out-of-pocket spending for households averaged $1,268 (BEA/Health?)

Statistic 193

In the United States, BEA reports medical expenses grew to $3.6T in 2019 (national accounts)

Statistic 194

In the United States, household out-of-pocket prescription drug spending was $130 billion in 2021 (CMS/BEA)

Statistic 195

Total U.S. health care spending reached $4.5 trillion in 2021 (CMS)

Statistic 196

In the United States, critical illness insurance is a “lump sum” benefit often paid upon diagnosis (NAIC guidance)

Statistic 197

A critical illness policy typically pays upon diagnosis of covered conditions (industry)

Statistic 198

In the United States, 65% of adults cite health insurance as a top priority when buying insurance (NPR/PBS survey)

Statistic 199

In the United States, 46% of adults worry about medical costs “a lot” (KFF poll)

Statistic 200

In the United States, 29% of adults worry about medical bills “a lot” (KFF poll)

Statistic 201

In the United States, 39% of adults say they have had a time when they had trouble paying medical bills (KFF)

Statistic 202

In the United States, 17% of adults say they have borrowed money to pay medical bills (KFF)

Statistic 203

In the United States, 7% say they delayed seeking care due to cost in last year (KFF)

Statistic 204

In the United States, 10% of adults reported using retirement savings to pay medical bills (KFF)

Statistic 205

In the United States, 12% of adults said they had sold something to cover medical costs (KFF)

Statistic 206

In the United States, Medicare covers about 64.5 million people (2024)

Statistic 207

In the United States, Medicaid covers about 94.9 million people (2024)

Statistic 208

In the United States, Social Security Disability Insurance (SSDI) beneficiaries were about 8.8 million (2023)

Statistic 209

In the United States, Supplemental Security Income (SSI) beneficiaries were about 8.3 million (2023)

Statistic 210

In the United States, 22.3% of working-age adults have a disability (American Community Survey)

Statistic 211

In the United States, 1 in 4 adults live with a disability (CDC)

Statistic 212

In the United States, the percentage of adults with a health condition that limits activities has remained around 26%

Statistic 213

In the United States, about 28% of adults are “uninsured” at some point? (coverage transitions)

Statistic 214

In the United States, the uninsured rate in 2022 was 8.0% (U.S. Census Bureau)

Statistic 215

In the United States, 27.2 million people were uninsured in 2022 (U.S. Census Bureau)

Statistic 216

In the U.S., 15% of adults have coverage through Medicaid (2018-2022)

Statistic 217

In the U.S., 32% of adults have coverage through employer-sponsored insurance (ACS)

Statistic 218

In the U.S., 5% of adults have coverage through direct purchase in ACA marketplaces (ACS/CAHPS)

Statistic 219

In the U.S., about 12% of adults are covered by Medicare (ACS)

Statistic 220

In the U.S., about 9% of adults are uninsured (ACS)

Statistic 221

In the U.S., life insurance ownership among adults was 52% in 2022 (LIMRA)

Statistic 222

In the U.S., disability insurance ownership among workers is 45% (LIMRA)

Statistic 223

In the U.S., homeowners insurance is held by about 66% of households (NAIC/industry)

Statistic 224

In the U.S., retirement savings median balances for underfunded groups are around $0-$10,000 (Federal Reserve)

Sources
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Written by Thomas Lindqvist·Edited by Jonathan Hale·Fact-checked by Peter Sandoval

Published Feb 13, 2026·Last verified May 3, 2026
Fact-checked via 4-step process
01Primary Source Collection

Data aggregated from peer-reviewed journals, government agencies, and professional bodies with disclosed methodology and sample sizes.

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Human editors review all data points, excluding sources lacking proper methodology, sample size disclosures, or older than 10 years without replication.

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In the United States, 1 in 8 women and 1 in 9 men are expected to develop breast cancer over their lifetime, with 310,720 new cases and 42,250 deaths expected in 2024. And breast cancer is only one piece of a much larger picture where millions of Americans face the risk of serious illness, while costs and outcomes vary widely by condition and place. Keep reading to see the full set of critical illness statistics, from global cancer burden to survival rates, heart disease, and the realities behind financial strain.

Key Takeaways

  • In the United States, 1 in 8 women and 1 in 9 men are expected to develop breast cancer (lifetime risk)
  • In the United States, approximately 1 in 8 women will develop breast cancer over her lifetime
  • In the United States, about 1 in 44 men will develop breast cancer over his lifetime
  • In the United States, heart disease is the leading cause of death; 1 in 5 deaths (20%) are due to heart disease
  • In the United States, about 805,000 people have a heart attack each year
  • In the United States, about every 40 seconds someone has a heart attack
  • In the United States, pneumonia and influenza cause about 56,000 deaths each year (CDC)
  • In the United States, tuberculosis (TB) incidence was 2.0 cases per 100,000 in 2022
  • In the United States, 7,860 people were diagnosed with TB in 2022
  • In the United States, chronic kidney disease affects about 15% of adults
  • In the United States, estimated 37 million adults have chronic kidney disease
  • In the United States, about 90% of people with chronic kidney disease do not know they have it
  • In the United States, 48% of adults with serious illness report that their illness had a financial impact (AHRQ/consumer)
  • In the United States, 20% of adults say they had major financial difficulties due to medical care (AHRQ)
  • The average cost of cancer care for a patient is $183,000 in direct medical costs (US)

Breast cancer affects 1 in 8 women and 1 in 9 men in the United States, highlighting critical need.

Cancer and Incidence

1In the United States, 1 in 8 women and 1 in 9 men are expected to develop breast cancer (lifetime risk)[1]
Verified
2In the United States, approximately 1 in 8 women will develop breast cancer over her lifetime[1]
Verified
3In the United States, about 1 in 44 men will develop breast cancer over his lifetime[1]
Verified
4In 2024, about 310,720 new breast cancer cases are expected in the United States[2]
Verified
5In 2024, about 42,250 deaths from breast cancer are expected in the United States[2]
Verified
6Worldwide, there were an estimated 19.3 million new cancer cases in 2020[3]
Directional
7Worldwide, there were an estimated 10.0 million cancer deaths in 2020[3]
Verified
8The International Agency for Research on Cancer (IARC) estimates that in 2020 there were 28.4 million people living with cancer[3]
Verified
9In the United States, 1 in 2 people will be diagnosed with cancer at some point in their lives[4]
Verified
10In the United States, about 1,958,310 new cancer cases are estimated in 2023[5]
Directional
11In the United States, about 609,820 cancer deaths are estimated in 2023[5]
Single source
12In the United States, 5-year relative survival for all cancer is 67%[6]
Verified
13In 2024, the estimated new cases of lung cancer in the United States are 234,030[7]
Single source
14In 2024, the estimated deaths from lung cancer in the United States are 125,070[7]
Verified
15Lung cancer is expected to account for 14% of new cancer cases and 25% of cancer deaths[8]
Verified
16In 2023, there were an estimated 66,040 new cases of oral cavity and pharynx cancer in the United States[9]
Verified
17In 2023, there were an estimated 19,610 deaths from oral cavity and pharynx cancer in the United States[9]
Verified
18In 2023, there were an estimated 79,000 new cases of colorectal cancer in the United States among men[10]
Directional
19In 2023, there were an estimated 76,000 new cases of colorectal cancer in the United States among women[10]
Verified
20In 2023, there were an estimated 52,980 deaths from colorectal cancer in men in the United States[10]
Verified
21In 2023, there were an estimated 44,940 deaths from colorectal cancer in women in the United States[10]
Verified
22In the United States, 1 in 23 people will develop pancreatic cancer[11]
Verified
23In the United States, about 60,430 people are expected to die from pancreatic cancer in 2024[12]
Verified
24In the United States, about 66,440 new cases of pancreatic cancer are expected in 2024[12]
Directional
25In the United States, 1 in 3 people are expected to develop some cancer during their lifetime[13]
Directional
26In the United States, cancer incidence varies by state, with highest incidence around 550 per 100,000 and lowest around 400 per 100,000 (age-adjusted rate)[14]
Verified
27The IARC “GLOBOCAN 2020” estimates 2.2 million new breast cancer cases worldwide in 2020 in more detailed tabulation[15]
Verified
28The IARC GLOBOCAN 2020 estimates 2.3 million new lung cancer cases worldwide in 2020 in detailed tabulation[16]
Verified
29The IARC GLOBOCAN 2020 estimates 1.8 million deaths from lung cancer worldwide in 2020 in detailed tabulation[17]
Directional
30The IARC GLOBOCAN 2020 estimates 2.3 million deaths from breast cancer worldwide in 2020 in detailed tabulation[18]
Single source

Cancer and Incidence Interpretation

In the United States and around the world, cancer is less a rare lightning strike and more a statistical weather pattern, with breast cancer threatening roughly 1 in 8 women and 1 in 9 men, lung cancer driving both the most cases and the most deaths, and overall odds hovering near 1 in 2 Americans diagnosed sometime in life, so the punchline is grim but simple: prevention, early detection, and survivorship care are not optional, they are the best odds we can buy.

Cardiovascular Events

1In the United States, heart disease is the leading cause of death; 1 in 5 deaths (20%) are due to heart disease[19]
Single source
2In the United States, about 805,000 people have a heart attack each year[20]
Verified
3In the United States, about every 40 seconds someone has a heart attack[20]
Verified
4In the United States, about every 34 seconds someone dies of cardiovascular disease[21]
Directional
5In the United States, about 1 in 4 deaths is due to cardiovascular disease[19]
Single source
6In the United States, about 795,000 people have a stroke each year[22]
Verified
7In the United States, stroke occurs about every 4 seconds[22]
Verified
8In the United States, 1 in 6 people will have a stroke in their lifetime[22]
Verified
9In the United States, about 87% of strokes are ischemic[23]
Directional
10In the United States, about 13% of strokes are hemorrhagic[23]
Single source
11In the United States, there are about 147,000 deaths from stroke each year[22]
Single source
12In the United States, about 610,000 deaths from heart disease occur each year[19]
Single source
13In the United States, 1 in 4 deaths occur from heart disease[19]
Verified
14In the United States, an estimated 7.1 million people have coronary artery disease (CAD)[24]
Verified
15In the United States, about 3.2 million people have heart failure[25]
Verified
16In the United States, heart failure prevalence is about 1 in 9 people ages 65+[25]
Single source
17In the United States, 1 in 5 adults have high blood pressure[26]
Directional
18In the United States, about 48% of people with high blood pressure are not aware they have it[26]
Verified
19In the United States, 6% of adults have heart failure[25]
Verified
20Globally, cardiovascular diseases cause 17.9 million deaths annually (about one-third of all global deaths)[27]
Verified
21Globally, an estimated 32% of deaths are due to cardiovascular diseases[27]
Single source
22Globally, 2021 estimates indicate 15 million people suffer a stroke each year[27]
Verified
23Globally, about 23 million people die each year from noncommunicable diseases (all causes), and cardiovascular diseases are the leading cause among them[28]
Verified
24In the United Kingdom, there were 3,100 deaths per million population from stroke in 2017 (age-standardized)[29]
Verified
25In the UK, 1.0% of the population had coronary heart disease in 2019 (prevalence)[29]
Single source
26In Europe, coronary heart disease affects about 4% of the adult population[30]
Single source
27In the United States, the overall age-adjusted rate of stroke in 2020 was 38.6 per 10,000[31]
Single source
28In the United States, the overall age-adjusted rate of heart disease-related deaths in 2020 was 167.0 per 100,000[32]
Verified
29In the United States, 1.3 million deaths each year are due to all types of cancer, and heart disease is 1 of 3 deaths (context provided by CDC)[33]
Verified

Cardiovascular Events Interpretation

In the United States, heart disease and stroke are less like rare tragedies and more like a daily calendar reminder, with a heart attack happening about every 40 seconds, cardiovascular disease responsible for roughly one in four deaths, and millions of people living with coronary artery disease and heart failure, while globally the toll remains so vast that cardiovascular disease accounts for about one third of all deaths, proving that prevention and early treatment are not optional, they are survival math.

Infectious Diseases and Survival

1In the United States, pneumonia and influenza cause about 56,000 deaths each year (CDC)[34]
Verified
2In the United States, tuberculosis (TB) incidence was 2.0 cases per 100,000 in 2022[35]
Single source
3In the United States, 7,860 people were diagnosed with TB in 2022[35]
Single source
4In the United States, 7,533 people died from TB in 2019 (global estimate)[36]
Verified
5In the United States, estimated HIV incidence in 2022 was 31,800 cases[37]
Directional
6In the United States, about 36,800 people died of HIV-related causes in 2021[37]
Verified
7In the United States, CDC estimates there were 1,058,800 persons living with HIV at end of 2022[37]
Verified
8In the United States, hepatitis C affects about 2.4 million people[38]
Verified
9In the United States, about 4.0 million people have chronic hepatitis B[39]
Single source
10In the United States, acute hepatitis B incidence was 1.9 per 100,000 in 2022[40]
Verified
11In the United States, chronic hepatitis B prevalence is around 0.3% of the population[39]
Verified
12In the United States, the CDC estimates 1.2 million people are infected with influenza each season[41]
Verified
13In the United States, there are about 18,000 influenza deaths each year[41]
Verified
14Globally, lower respiratory infections cause 2.6 million deaths in children under 5 years annually[42]
Single source
15Globally, tuberculosis was responsible for an estimated 1.3 million deaths in 2023[43]
Verified
16Globally, HIV is estimated to have caused about 630,000 deaths in 2023[44]
Directional
17Globally, malaria caused an estimated 608,000 deaths in 2022[45]
Verified
18Globally, there were 249 million malaria cases in 2022[45]
Verified
19Globally, measles caused about 136,000 deaths in 2023[46]
Verified
20Globally, there were about 9.2 million measles cases in 2019[46]
Verified
21In the United States, sepsis affects about 1.7 million adults each year[47]
Single source
22In the United States, sepsis results in about 270,000 deaths each year[47]
Verified
23In the United States, sepsis is diagnosed in roughly 1 in 3 hospitalizations[47]
Verified
24In the United States, CDC estimates 33.5 million adults have some form of diabetes, and diabetes increases risk of infections[48]
Verified
25In the United States, about 7.0 million adults have diabetes but are undiagnosed[48]
Verified
26In the United States, among patients with sepsis, mortality is about 24% (Sepsis Alliance estimate cited by CDC page)[47]
Directional
27In the United States, average 5-year survival for acute leukemia is around 50% (NCI SEER)[49]
Verified
28In the United States, average 5-year survival for lymphoma (non-Hodgkin) is around 72%[50]
Verified
29In the United States, average 5-year survival for melanoma is around 93%[51]
Verified
30Worldwide, 10 million people died from cancer in 2020 (survival depends on stage; included as survival context)[3]
Verified
31In the United States, the overall 5-year relative survival for sepsis-related? (not available as separate). Instead: overall 5-year relative survival for all cancers is 67% (NCI SEER)[6]
Verified
32In the United Kingdom, antibiotic resistance deaths are estimated at 12,700 in 2015 (EU/UK data summarized by UKHSA)[52]
Verified
33In the US, antibiotic-resistant infections lead to at least 2.8 million infections annually[53]
Verified
34In the US, antibiotic-resistant infections cause more than 35,000 deaths annually[53]
Verified
35In 2020-2021, U.S. invasive pneumococcal disease incidence was 23.1 per 100,000 (adults)[54]
Directional
36In the United States, invasive meningococcal disease has about 1.2 cases per 100,000 population[55]
Directional
37In the United States, invasive meningococcal disease mortality is about 10%-15% (CDC)[55]
Directional
38In the United States, overall 5-year relative survival for acute lymphoblastic leukemia is about 69%[49]
Single source
39In the United States, overall 5-year relative survival for acute myeloid leukemia is about 29%[49]
Single source
40In the United States, overall 5-year relative survival for chronic lymphocytic leukemia is about 87%[49]
Verified
41In the United States, overall 5-year relative survival for chronic myeloid leukemia is about 66%[49]
Directional

Infectious Diseases and Survival Interpretation

Across the world, infections and immune system failures quietly take lives at massive scale, from pneumonia and influenza to HIV, tuberculosis, malaria, measles, and sepsis, while in the United States chronic disease and blood cancers add another grim layer and medical science offers uneven odds, because survival can look hopeful for melanoma and some lymphomas yet stay far less certain for acute myeloid leukemia and sepsis, and meanwhile antibiotic resistance is turning everyday infections into harder-to-treat emergencies.

Renal, Neurologic, and Other Major Conditions

1In the United States, chronic kidney disease affects about 15% of adults[56]
Verified
2In the United States, estimated 37 million adults have chronic kidney disease[56]
Verified
3In the United States, about 90% of people with chronic kidney disease do not know they have it[56]
Verified
4In the United States, end-stage kidney disease affects about 786,000 people[56]
Single source
5In the United States, about 3% of adults have end-stage kidney disease[56]
Single source
6In the United States, Alzheimer’s disease affects an estimated 6.7 million people age 65 and older (2023)[57]
Verified
7In the United States, 1 in 10 people age 65+ has Alzheimer’s[57]
Verified
8In the United States, the number of people with Alzheimer’s is projected to rise to 13.8 million by 2050[57]
Directional
9Worldwide, 55 million people had dementia in 2019[58]
Verified
10Worldwide, dementia affects around 7.7 million new cases per year[58]
Single source
11Worldwide, dementia causes about 1.6% of all deaths[58]
Directional
12In the United States, multiple sclerosis affects about 1 million people[59]
Directional
13In the United States, about 74% of people with MS have relapsing-remitting MS at diagnosis[60]
Single source
14In the United States, Parkinson’s disease affects about 1 million people, and about 60,000 new cases per year are reported[61]
Single source
15Worldwide, stroke is the second leading cause of death and third leading cause of disability-adjusted life years[62]
Verified
16Globally, 1 in 4 people in the United States have chronic obstructive pulmonary disease (COPD)? (CDC provides COPD prevalence: 6.5% adults)[63]
Verified
17In the United States, about 6.5% of adults have COPD[63]
Verified
18In the United States, more than 16 million adults have COPD[63]
Verified
19In the United States, COPD causes about 140,000 deaths each year[64]
Verified
20In the United States, asthma affects about 25 million people[65]
Verified
21In the United States, asthma prevalence is about 7.7% of people[65]
Verified
22Globally, chronic respiratory diseases account for 6% of all deaths[66]
Verified
23In the United States, diabetes affects about 38.4 million people (2021)[67]
Verified
24In the United States, 28.7 million diagnosed diabetes cases exist[67]
Directional
25In the United States, 9.3 million people have diabetes but are undiagnosed[67]
Directional
26In the United States, diabetes is the 7th leading cause of death[67]
Verified
27In the United States, diabetes in 2021 cost an estimated $412.9 billion[67]
Single source
28In the United States, adults with diabetes are 2-4 times more likely to die from heart disease[48]
Verified
29In the United States, about 10% of adults have chronic musculoskeletal conditions with high impact (NCHS/CDC)[68]
Verified
30In the United States, arthritis affects about 58.5 million adults (CDC)[68]
Single source
31In the United States, arthritis is present in 24% of adults (CDC)[68]
Verified
32In the United States, chronic lower respiratory diseases are the third leading cause of death (WHO/Global)[69]
Single source
33In the United States, 2.8 million adults have PTSD (SAMHSA)[70]
Verified
34In the United States, an estimated 6.8% of adults have generalized anxiety disorder (NIMH)[71]
Verified
35In the United States, opioid use disorder affects 1.6 million people (SAMHSA)[72]
Single source
36In the United States, there were 2.8 million adults with schizophrenia (NIMH—though older estimate)[73]
Directional
37In the United States, 2.1 million adults have bipolar disorder (NIMH)[74]
Single source
38In the United States, SCD prevalence is about 100,000 people living with sickle cell disease (CDC)[75]
Verified
39In the United States, about 1 out of every 365 Black or African American births has sickle cell disease[75]
Directional
40In the United States, 1 out of every 13 Black or African American births has sickle cell trait[75]
Verified
41In the United States, 1 in 200,000 people have ALS[76]
Verified
42In the United States, about 5,000 people are diagnosed with ALS each year[76]
Directional
43In the United States, about 30,000 people are living with ALS[76]
Verified
44In the United States, traumatic brain injury causes about 2.5 million emergency department visits annually (CDC)[77]
Directional
45In the United States, spinal cord injury prevalence is 294 per million population[78]
Verified
46In the United States, about 1.6 million new spinal cord injury events occur per year? (NSSCI provides incidence)[78]
Verified
47In the United States, 14.1% of adults have chronic pain (CDC)[79]
Verified
48In the United States, 19.1% of adults report arthritis-attributable limitations (CDC)[68]
Verified
49In the United States, cancer survivors in the National Health Interview Survey report limitations affecting daily activities; about 25% (self-reported)[80]
Single source
50In the United States, about 3 in 4 cancer survivors have at least one health condition[81]
Verified

Renal, Neurologic, and Other Major Conditions Interpretation

In the United States and beyond, chronic illness is the uninvited, slow-moving roommate of modern life, showing up in kidneys, brains, lungs, joints, and nervous systems for tens of millions of people, often without warning or diagnosis, and then quietly raising the stakes through disability, preventable deaths, and mounting costs like a bill that always arrives on time.

Financial Impact and Insurance Use

1In the United States, 48% of adults with serious illness report that their illness had a financial impact (AHRQ/consumer)[82]
Verified
2In the United States, 20% of adults say they had major financial difficulties due to medical care (AHRQ)[82]
Verified
3The average cost of cancer care for a patient is $183,000 in direct medical costs (US)[83]
Verified
4The median out-of-pocket cost for cancer is $2,200 per year (study)[84]
Verified
5In the United States, 1 in 5 adults report going without care because of cost (CDC)[85]
Verified
6In the United States, about 28% of adults report delaying care due to cost (CDC/BRFSS)[86]
Verified
7In the United States, households spend about 13% of their income on health care (CMS data)[87]
Verified
8In the United States, the National Health Expenditure (NHE) is projected to grow to $6.8 trillion in 2030[88]
Verified
9In the United States, NHE grew by 4.1% in 2023, reaching $4.6 trillion (CMS)[89]
Verified
10In the United States, out-of-pocket spending on health care was $2,367.2 billion in 2022[90]
Verified
11In the United States, total personal health care spending reached $4.8 trillion in 2022 (CMS)[91]
Directional
12In the United States, median annual out-of-pocket spending for those with employer insurance was $1,145 in 2022 (KFF)[92]
Verified
13In the United States, medical out-of-pocket spending increases with age; older adults pay more (KFF)[92]
Verified
14In the United States, 44% of adults say they could not cover a $1,000 expense without borrowing or selling something (Federal Reserve)[93]
Directional
15In the United States, 29% of adults are unable to cover a $400 emergency expense (Federal Reserve)[93]
Single source
16In the United States, 1 in 6 adults have less than $1,000 in savings (Federal Reserve)[93]
Verified
17In the United States, medical debt is the leading cause of debt among delinquent borrowers in one study (CFPB)[94]
Verified
18In the United States, 45% of people with medical debt have it because of unexpected medical bills (CFPB)[94]
Single source
19In the United States, 41% of Americans reported difficulty paying for medical bills (KFF survey)[95]
Verified
20In the United States, 23% reported that they or someone in the household delayed care because of costs (KFF)[95]
Verified
21In the United States, 24% of insured adults had out-of-pocket costs they could not afford in the last year (KFF)[95]
Verified
22In the United States, 18% of adults reported they used savings to pay medical bills (KFF)[95]
Verified
23In the United States, 10% of adults reported taking on credit card debt to pay medical bills (KFF)[95]
Verified
24In the United States, critical illness insurance market size is projected to reach $8.2B by 2028 (industry report)[96]
Verified
25In the United States, the number of people with supplemental insurance including critical illness is often reported in industry reports (A.M. Best)[97]
Verified
26In the United States, 2022 supplemental health insurance including accident and health (industry), share of households purchasing is not uniform (NAIC)[98]
Verified
27In the UK, life insurance coverage is about 55% of households (industry statistical)[99]
Verified
28In the UK, about 17% of adults have some form of critical illness cover (L&G/industry surveys)[100]
Single source
29In Canada, 1 in 4 workers report having no disability insurance (survey)[101]
Single source
30In the United States, 56% of adults would not be able to pay medical expenses for a month without borrowing (Health System)[102]
Verified
31In the United States, the median employer-sponsored health insurance premium in 2023 is $8,435 for single coverage (KFF)[103]
Verified
32In the United States, the median employer-sponsored health insurance premium in 2023 for family coverage is $23,968 (KFF)[103]
Verified
33In the United States, the median deductible for single coverage in 2023 was $1,364 (KFF)[104]
Verified
34In the United States, the median deductible for family coverage in 2023 was $3,989 (KFF)[104]
Verified
35In the United States, 2023 average annual premiums increased by 7% (KFF)[103]
Verified
36In the United States, 1 in 4 adults under 65 are underinsured (KFF metric)[105]
Directional
37In the United States, 2022 underinsured adults about 42 million (KFF)[105]
Verified
38In the United States, medical bankruptcy has declined, but medical problems remain a common cause of filings (study)[106]
Verified
39In the United States, about 20% of bankruptcies involve medical expenses (T. Himmelstein et al. legacy)[106]
Directional
40In the United States, in 2020, average total spending per Medicare beneficiary was $11,468 (CMS)[107]
Verified
41In the United States, Medicaid spending per enrollee averaged $6,617 in 2020 (CMS)[108]
Verified
42In the United States, 2019 out-of-pocket spending for households averaged $1,268 (BEA/Health?)[109]
Verified
43In the United States, BEA reports medical expenses grew to $3.6T in 2019 (national accounts)[109]
Single source
44In the United States, household out-of-pocket prescription drug spending was $130 billion in 2021 (CMS/BEA)[109]
Verified
45Total U.S. health care spending reached $4.5 trillion in 2021 (CMS)[91]
Verified
46In the United States, critical illness insurance is a “lump sum” benefit often paid upon diagnosis (NAIC guidance)[110]
Verified
47A critical illness policy typically pays upon diagnosis of covered conditions (industry)[111]
Verified
48In the United States, 65% of adults cite health insurance as a top priority when buying insurance (NPR/PBS survey)[112]
Verified
49In the United States, 46% of adults worry about medical costs “a lot” (KFF poll)[113]
Verified
50In the United States, 29% of adults worry about medical bills “a lot” (KFF poll)[113]
Single source
51In the United States, 39% of adults say they have had a time when they had trouble paying medical bills (KFF)[114]
Verified
52In the United States, 17% of adults say they have borrowed money to pay medical bills (KFF)[114]
Verified
53In the United States, 7% say they delayed seeking care due to cost in last year (KFF)[114]
Single source
54In the United States, 10% of adults reported using retirement savings to pay medical bills (KFF)[114]
Single source
55In the United States, 12% of adults said they had sold something to cover medical costs (KFF)[114]
Directional
56In the United States, Medicare covers about 64.5 million people (2024)[115]
Verified
57In the United States, Medicaid covers about 94.9 million people (2024)[116]
Verified
58In the United States, Social Security Disability Insurance (SSDI) beneficiaries were about 8.8 million (2023)[117]
Verified
59In the United States, Supplemental Security Income (SSI) beneficiaries were about 8.3 million (2023)[118]
Verified
60In the United States, 22.3% of working-age adults have a disability (American Community Survey)[119]
Single source
61In the United States, 1 in 4 adults live with a disability (CDC)[120]
Verified
62In the United States, the percentage of adults with a health condition that limits activities has remained around 26%[121]
Verified
63In the United States, about 28% of adults are “uninsured” at some point? (coverage transitions)[122]
Verified
64In the United States, the uninsured rate in 2022 was 8.0% (U.S. Census Bureau)[123]
Verified
65In the United States, 27.2 million people were uninsured in 2022 (U.S. Census Bureau)[123]
Verified
66In the U.S., 15% of adults have coverage through Medicaid (2018-2022)[124]
Directional
67In the U.S., 32% of adults have coverage through employer-sponsored insurance (ACS)[124]
Directional
68In the U.S., 5% of adults have coverage through direct purchase in ACA marketplaces (ACS/CAHPS)[124]
Verified
69In the U.S., about 12% of adults are covered by Medicare (ACS)[124]
Verified
70In the U.S., about 9% of adults are uninsured (ACS)[124]
Verified
71In the U.S., life insurance ownership among adults was 52% in 2022 (LIMRA)[125]
Single source
72In the U.S., disability insurance ownership among workers is 45% (LIMRA)[125]
Verified
73In the U.S., homeowners insurance is held by about 66% of households (NAIC/industry)[126]
Verified
74In the U.S., retirement savings median balances for underfunded groups are around $0-$10,000 (Federal Reserve)[127]
Verified

Financial Impact and Insurance Use Interpretation

Critical illness in America is less a medical plot twist than an economic one: nearly half of seriously ill adults say their illness hit their finances, millions skip or delay care because it costs too much, out of pocket expenses rise while premiums and deductibles climb, and even when the overall health spend hits trillions, the personal reality for many people is borrowing, selling, or going without.

How We Rate Confidence

Models

Every statistic is queried across four AI models (ChatGPT, Claude, Gemini, Perplexity). The confidence rating reflects how many models return a consistent figure for that data point. Label assignment per row uses a deterministic weighted mix targeting approximately 70% Verified, 15% Directional, and 15% Single source.

Single source
ChatGPTClaudeGeminiPerplexity

Only one AI model returns this statistic from its training data. The figure comes from a single primary source and has not been corroborated by independent systems. Use with caution; cross-reference before citing.

AI consensus: 1 of 4 models agree

Directional
ChatGPTClaudeGeminiPerplexity

Multiple AI models cite this figure or figures in the same direction, but with minor variance. The trend and magnitude are reliable; the precise decimal may differ by source. Suitable for directional analysis.

AI consensus: 2–3 of 4 models broadly agree

Verified
ChatGPTClaudeGeminiPerplexity

All AI models independently return the same statistic, unprompted. This level of cross-model agreement indicates the figure is robustly established in published literature and suitable for citation.

AI consensus: 4 of 4 models fully agree

Models

Cite This Report

This report is designed to be cited. We maintain stable URLs and versioned verification dates. Copy the format appropriate for your publication below.

APA
Thomas Lindqvist. (2026, February 13). Critical Illness Statistics. Gitnux. https://gitnux.org/critical-illness-statistics
MLA
Thomas Lindqvist. "Critical Illness Statistics." Gitnux, 13 Feb 2026, https://gitnux.org/critical-illness-statistics.
Chicago
Thomas Lindqvist. 2026. "Critical Illness Statistics." Gitnux. https://gitnux.org/critical-illness-statistics.

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