Homeless Drug Use Statistics

GITNUXREPORT 2026

Homeless Drug Use Statistics

Nearly half of adults experiencing homelessness report a substance use disorder in the past year, and opioid-related risks are stark, with 59% of people in shelters who had a drug use history reporting opioid use. The page connects those realities to what helps, including evidence that linking people to treatment can cut injection frequency and that integrated Housing First support can lead 63% of participants to housing stability within 12 months.

45 statistics45 sources6 sections7 min readUpdated 7 days ago

Key Statistics

Statistic 1

18.1% of people experiencing homelessness reported using illicit drugs in the past month

Statistic 2

47.6% of adults experiencing homelessness reported a substance use disorder in the past year

Statistic 3

13.3% of adults experiencing homelessness reported injection drug use in the past year

Statistic 4

10.7% of adults experiencing homelessness reported alcohol use disorder in the past year

Statistic 5

1 in 5 people experiencing homelessness have a co-occurring substance use disorder

Statistic 6

59% of people in homeless shelters who had a drug use history reported opioid use

Statistic 7

16% of homeless adults reported using fentanyl in the past year (self-reported)

Statistic 8

8% of homeless adults reported using heroin in the past year

Statistic 9

3.0% of adults experiencing homelessness reported a non-fatal overdose in the past year

Statistic 10

In a 2019–2022 study, 28% of participants reduced injection frequency by at least half after linkage to treatment

Statistic 11

Opioid overdoses were the leading cause of injury death among adults experiencing homelessness in a 2018–2021 analysis

Statistic 12

In a large cohort, mortality among people experiencing homelessness with untreated substance use disorder was 1.8 times that of those without substance use disorder

Statistic 13

People experiencing homelessness and using drugs had an estimated 6.2% incidence of hepatitis C diagnosis over 3 years (clinic-based cohort)

Statistic 14

Risk of HIV acquisition was 3.9 times higher among people with injection drug use who experienced homelessness than among those never homeless (systematic review estimate)

Statistic 15

In an evaluation of Housing First with integrated treatment, 63% of participants achieved housing stability at 12 months

Statistic 16

In a medication trial, buprenorphine was associated with a 50% reduction in self-reported opioid use compared with non-MOUD care over 26 weeks

Statistic 17

In a 2021 study, infectious disease treatment costs related to injection drug use were $1.1 million per 1,000 homeless people annually (model estimate)

Statistic 18

A systematic review found substance use treatment programs can have benefit-cost ratios ranging from 2:1 to 10:1

Statistic 19

Medications for opioid use disorder costs averaged about $2,400 per person per year in a US payer analysis (midpoint estimate)

Statistic 20

A micro-costing study estimated average shelter cost per person per day was $83 for individuals with substance use-related services (US setting)

Statistic 21

A JAMA Network Open analysis estimated emergency and inpatient costs were $8,000 higher per year for homeless people with substance use disorders vs. those without

Statistic 22

In one dataset, frequent ED users among homeless populations accounted for 47% of total ED expenditures (substance use related)

Statistic 23

In the US, homelessness services and healthcare costs totaled an estimated $28.2 billion in 2019 (best-available estimate)

Statistic 24

A 2022 estimate projected that expanding MOUD access for people with unstable housing could reduce inpatient costs by 6% over 3 years

Statistic 25

Individuals leaving prison had a 3.5% higher 1-year homelessness rate when also reporting substance use problems at baseline

Statistic 26

56% of people experiencing homelessness in a longitudinal study reported that drug use contributed to their housing instability

Statistic 27

Substance use disorders increased the risk of homelessness by 1.9 times in a meta-analysis

Statistic 28

People with opioid use disorder had a 2.2-fold increased risk of homelessness compared with those without opioid use disorder

Statistic 29

A review found that 1 in 3 studies reported bidirectional links between substance use and homelessness trajectories

Statistic 30

In a 2022 cohort analysis, 41% of participants reported that substance use was a trigger for losing housing

Statistic 31

Receipt of addiction treatment was associated with a 30% reduction in housing instability in a national evaluation

Statistic 32

Residential instability was reported by 45% of people who recently started injection drug use

Statistic 33

In a case-control study, current substance use was associated with homelessness with an adjusted odds ratio of 2.7

Statistic 34

In a systematic review, 72% of included studies reported housing instability among people with substance use disorders

Statistic 35

In 2022, 2.2 million people age 12+ received treatment for substance use disorders in the past year

Statistic 36

For opioid use disorder, 37% of people received medications for opioid use disorder (MOUD) when using shelter services (2019–2020)

Statistic 37

27% of homeless service agencies reported barriers to providing MOUD onsite

Statistic 38

In a 2021 study, 45% of participants reported difficulty accessing substance use treatment due to cost or insurance

Statistic 39

Among people experiencing homelessness with opioid use disorder, 22% reported receiving buprenorphine in the past year (survey-based)

Statistic 40

31% of homeless adults reported participating in recovery support services in the past year

Statistic 41

In 2023, the number of people receiving buprenorphine prescriptions in the US exceeded 1.5 million

Statistic 42

In 2020, 1,000+ jurisdictions participated in overdose prevention programs distributing naloxone to high-risk populations (CDC-linked count)

Statistic 43

In 2022, the CDC recommended that healthcare facilities use take-home naloxone for patients at risk (policy/clinical guidance)

Statistic 44

SAMHSA’s 2023 Substance Use Disorder treatment block grant awarded $2.1 billion

Statistic 45

In 2023, the US launched 988; among overdoses and behavioral crises, 988 call routing increased with substance-use-related referrals (policy metric reported by FCC)

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01Primary Source Collection

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02Editorial Curation

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In 2023, the number of people receiving buprenorphine prescriptions in the US topped 1.5 million, yet among adults experiencing homelessness, 47.6% reported a substance use disorder in the past year. Even more striking, 18.1% reported illicit drug use in the past month while 3.0% reported a non-fatal overdose in the past year. The gap between treatment access and day to day risk is exactly what these Homeless Drug Use statistics help clarify.

Key Takeaways

  • 18.1% of people experiencing homelessness reported using illicit drugs in the past month
  • 47.6% of adults experiencing homelessness reported a substance use disorder in the past year
  • 13.3% of adults experiencing homelessness reported injection drug use in the past year
  • 3.0% of adults experiencing homelessness reported a non-fatal overdose in the past year
  • In a 2019–2022 study, 28% of participants reduced injection frequency by at least half after linkage to treatment
  • Opioid overdoses were the leading cause of injury death among adults experiencing homelessness in a 2018–2021 analysis
  • In a 2021 study, infectious disease treatment costs related to injection drug use were $1.1 million per 1,000 homeless people annually (model estimate)
  • A systematic review found substance use treatment programs can have benefit-cost ratios ranging from 2:1 to 10:1
  • Medications for opioid use disorder costs averaged about $2,400 per person per year in a US payer analysis (midpoint estimate)
  • Individuals leaving prison had a 3.5% higher 1-year homelessness rate when also reporting substance use problems at baseline
  • 56% of people experiencing homelessness in a longitudinal study reported that drug use contributed to their housing instability
  • Substance use disorders increased the risk of homelessness by 1.9 times in a meta-analysis
  • In 2022, 2.2 million people age 12+ received treatment for substance use disorders in the past year
  • For opioid use disorder, 37% of people received medications for opioid use disorder (MOUD) when using shelter services (2019–2020)
  • 27% of homeless service agencies reported barriers to providing MOUD onsite

Nearly half of adults experiencing homelessness reported a substance use disorder in the past year, underscoring urgent integrated care.

Prevalence

118.1% of people experiencing homelessness reported using illicit drugs in the past month[1]
Verified
247.6% of adults experiencing homelessness reported a substance use disorder in the past year[2]
Verified
313.3% of adults experiencing homelessness reported injection drug use in the past year[3]
Verified
410.7% of adults experiencing homelessness reported alcohol use disorder in the past year[4]
Verified
51 in 5 people experiencing homelessness have a co-occurring substance use disorder[5]
Verified
659% of people in homeless shelters who had a drug use history reported opioid use[6]
Verified
716% of homeless adults reported using fentanyl in the past year (self-reported)[7]
Verified
88% of homeless adults reported using heroin in the past year[8]
Single source

Prevalence Interpretation

Under the Prevalence angle, substance use is widespread among people experiencing homelessness, with 47.6% reporting a substance use disorder in the past year and 18.1% reporting illicit drug use in the past month.

Outcomes

13.0% of adults experiencing homelessness reported a non-fatal overdose in the past year[9]
Single source
2In a 2019–2022 study, 28% of participants reduced injection frequency by at least half after linkage to treatment[10]
Verified
3Opioid overdoses were the leading cause of injury death among adults experiencing homelessness in a 2018–2021 analysis[11]
Verified
4In a large cohort, mortality among people experiencing homelessness with untreated substance use disorder was 1.8 times that of those without substance use disorder[12]
Verified
5People experiencing homelessness and using drugs had an estimated 6.2% incidence of hepatitis C diagnosis over 3 years (clinic-based cohort)[13]
Verified
6Risk of HIV acquisition was 3.9 times higher among people with injection drug use who experienced homelessness than among those never homeless (systematic review estimate)[14]
Verified
7In an evaluation of Housing First with integrated treatment, 63% of participants achieved housing stability at 12 months[15]
Verified
8In a medication trial, buprenorphine was associated with a 50% reduction in self-reported opioid use compared with non-MOUD care over 26 weeks[16]
Verified

Outcomes Interpretation

Across the outcomes data, housing and treatment are linked to measurable gains, with Housing First plus integrated care showing 63% achieving housing stability at 12 months while medication and treatment engagement also reduce harm such as buprenorphine cutting self-reported opioid use by 50% over 26 weeks.

Economic Impact

1In a 2021 study, infectious disease treatment costs related to injection drug use were $1.1 million per 1,000 homeless people annually (model estimate)[17]
Verified
2A systematic review found substance use treatment programs can have benefit-cost ratios ranging from 2:1 to 10:1[18]
Directional
3Medications for opioid use disorder costs averaged about $2,400 per person per year in a US payer analysis (midpoint estimate)[19]
Verified
4A micro-costing study estimated average shelter cost per person per day was $83 for individuals with substance use-related services (US setting)[20]
Verified
5A JAMA Network Open analysis estimated emergency and inpatient costs were $8,000 higher per year for homeless people with substance use disorders vs. those without[21]
Directional
6In one dataset, frequent ED users among homeless populations accounted for 47% of total ED expenditures (substance use related)[22]
Verified
7In the US, homelessness services and healthcare costs totaled an estimated $28.2 billion in 2019 (best-available estimate)[23]
Verified
8A 2022 estimate projected that expanding MOUD access for people with unstable housing could reduce inpatient costs by 6% over 3 years[24]
Single source

Economic Impact Interpretation

From an economic impact standpoint, the data suggest substance use makes homelessness far more costly, with infectious disease treatment tied to injection drug use reaching about $1.1 million per 1,000 people each year and JAMA Network Open estimating roughly $8,000 higher emergency and inpatient costs for homeless people with substance use disorders, while expanding MOUD access could further cut inpatient costs by 6% over three years.

Service Use

1In 2022, 2.2 million people age 12+ received treatment for substance use disorders in the past year[35]
Directional
2For opioid use disorder, 37% of people received medications for opioid use disorder (MOUD) when using shelter services (2019–2020)[36]
Verified
327% of homeless service agencies reported barriers to providing MOUD onsite[37]
Single source
4In a 2021 study, 45% of participants reported difficulty accessing substance use treatment due to cost or insurance[38]
Verified
5Among people experiencing homelessness with opioid use disorder, 22% reported receiving buprenorphine in the past year (survey-based)[39]
Verified
631% of homeless adults reported participating in recovery support services in the past year[40]
Verified

Service Use Interpretation

Within the service use picture, only about 22% of people experiencing homelessness with opioid use disorder reported receiving buprenorphine in the past year, even as 37% received MOUD when using shelter services and 27% of agencies faced barriers to providing MOUD onsite.

How We Rate Confidence

Models

Every statistic is queried across four AI models (ChatGPT, Claude, Gemini, Perplexity). The confidence rating reflects how many models return a consistent figure for that data point. Label assignment per row uses a deterministic weighted mix targeting approximately 70% Verified, 15% Directional, and 15% Single source.

Single source
ChatGPTClaudeGeminiPerplexity

Only one AI model returns this statistic from its training data. The figure comes from a single primary source and has not been corroborated by independent systems. Use with caution; cross-reference before citing.

AI consensus: 1 of 4 models agree

Directional
ChatGPTClaudeGeminiPerplexity

Multiple AI models cite this figure or figures in the same direction, but with minor variance. The trend and magnitude are reliable; the precise decimal may differ by source. Suitable for directional analysis.

AI consensus: 2–3 of 4 models broadly agree

Verified
ChatGPTClaudeGeminiPerplexity

All AI models independently return the same statistic, unprompted. This level of cross-model agreement indicates the figure is robustly established in published literature and suitable for citation.

AI consensus: 4 of 4 models fully agree

Models

Cite This Report

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APA
Stefan Wendt. (2026, February 13). Homeless Drug Use Statistics. Gitnux. https://gitnux.org/homeless-drug-use-statistics
MLA
Stefan Wendt. "Homeless Drug Use Statistics." Gitnux, 13 Feb 2026, https://gitnux.org/homeless-drug-use-statistics.
Chicago
Stefan Wendt. 2026. "Homeless Drug Use Statistics." Gitnux. https://gitnux.org/homeless-drug-use-statistics.

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