Top 10 Best Medical Claim Software of 2026

athenahealth is a leading cloud-based electronic health record (EHR) and revenue cycle management platform that specializes in medical claims processing, automating submission, scrubbing, and denial management for healthcare providers. It integrates seamlessly with EHR and practice management tools to streamline the entire revenue cycle, reducing errors and accelerating reimbursements. With advanced analytics and payer connectivity, athenahealth helps practices optimize cash flow and compliance in medical billing.

Kareo is a cloud-based revenue cycle management platform tailored for independent medical practices, excelling in medical claims processing, billing, and payment optimization. It automates claims submission via EDI, performs eligibility verification, scrubs claims for errors, and handles denial management to accelerate reimbursements. Integrated with EHR and practice management tools, it provides end-to-end visibility into financial workflows for healthcare providers.

AdvancedMD is a comprehensive cloud-based practice management and EHR platform with robust medical claims processing capabilities, enabling electronic claims submission, scrubbing, and denial management. It automates revenue cycle tasks like eligibility verification, payment posting, and AR tracking to minimize errors and accelerate reimbursements. Designed for healthcare providers, it integrates seamlessly with major payers and clearinghouses for efficient billing workflows.

Waystar is a comprehensive revenue cycle management (RCM) platform designed for healthcare providers, focusing on automating medical claims processing, submission, and payment optimization. It leverages AI and analytics to scrub claims, prevent denials, manage eligibility verification, and streamline patient payments. The solution integrates with major EHR systems and offers real-time insights to improve financial performance across hospitals and physician practices.

DrChrono is a comprehensive cloud-based EHR and practice management platform with robust medical claims processing capabilities, enabling automated submission of electronic claims (837P/837I) to over 3,000 payers. It features built-in claims scrubbing, denial management, real-time eligibility checks, and ERA posting to streamline revenue cycle management. Designed for small to mid-sized practices, it integrates billing seamlessly with clinical workflows, reducing errors and accelerating reimbursements.

NextGen Healthcare provides a comprehensive EHR and revenue cycle management platform with advanced medical claims software that automates claims creation, scrubbing, submission, and denial management. It integrates billing directly with clinical workflows to ensure accurate coding and faster reimbursements. Designed for ambulatory practices, it supports eligibility verification, AR management, and compliance reporting to optimize financial performance.

eClinicalWorks is a comprehensive EHR and practice management platform with robust medical claims software capabilities, enabling automated electronic claims submission, eligibility verification, and denial management. It integrates billing directly with patient records to minimize errors and accelerate reimbursements across multiple payers. The system also offers revenue cycle management tools, including AR tracking and remittance processing, making it suitable for diverse medical practices.

CollaborateMD is a cloud-based medical billing and practice management software tailored for healthcare providers, specializing in electronic claims submission, scrubbing, and revenue cycle management. It automates patient eligibility verification, payment posting, and denial management to minimize errors and accelerate reimbursements. The platform integrates with major clearinghouses and supports multi-specialty practices with tools for AR tracking and reporting.

Office Ally is a web-based medical billing and clearinghouse platform that enables healthcare providers to submit electronic claims (CMS-1500 and UB-04), perform eligibility verification, and process electronic remittance advice (ERA) for free in its basic version. It also offers integrated practice management tools like scheduling, reporting, and basic patient records to streamline revenue cycle management. While not a full-featured EHR, it focuses on cost-effective claims processing for small practices.

Availity is a leading healthcare platform that connects providers with over 1,000 payers for efficient revenue cycle management, including claims submission, eligibility verification, and payment processing. It supports full EDI capabilities, real-time claim status tracking, and electronic remittance advice (ERA) to reduce administrative burdens. The platform integrates with EHRs and practice management systems, offering analytics for denial management and workflow optimization.