Key Takeaways
- In a community sample of 1,006 children aged 8-9 years in Australia, the 12-month prevalence of separation anxiety disorder was 3.9%, with no significant gender difference.
- Among 9-16-year-olds in the Netherlands (N=2,160), point prevalence of SAD was 4.2% overall, rising to 5.1% in girls versus 3.3% in boys.
- US National Comorbidity Survey Replication Adolescent Supplement (NCS-A) reported lifetime SAD prevalence of 7.6% in youth aged 13-17, peaking at 8.2% for ages 13-14.
- Excessive distress when separation from home or attachment figures must occur, as manifested by at least three of eight DSM-5 symptoms persisting for 4 weeks in children under 18 or 6 months in adults.
- Persistent and excessive fear or anxiety about losing major attachment figures or about their possible maltreatment or death, occurring more frequently than expected given developmental level.
- Worry about experiencing an unhappy or untoward event (e.g., getting into an accident) that causes separation from attachment figure, reported in 72% of pediatric SAD cases.
- Family history of anxiety increases symptom severity by 2.3 fold in SAD probands.
- Temperamental behavioral inhibition at 14 months predicts SAD onset at 42.3% rate by age 7.
- Parental loss or separation (divorce) prior to age 6 triples SAD risk (OR=3.1).
- Cognitive Behavioral Therapy (CBT) for SAD yields 60-70% response rate in children after 12-16 sessions.
- Fluoxetine (SSRI) at 20-60mg/day reduces SAD symptoms by 50% in 71% of pediatric patients over 12 weeks.
- Parent-Child Interaction Therapy (PCIT) decreases separation behaviors by 65% in preschool SAD.
- 50% of child SAD remits by adolescence without treatment, but 30% persists into adulthood.
- Untreated SAD increases risk of adult panic disorder by 4-fold (OR=4.1).
- 65% of SAD children develop additional anxiety disorders by age 18.
Separation anxiety affects many children worldwide, with prevalence ranging between two to nine percent.






