Key Takeaways
- Approximately 25-30% of children aged 1-6 years in the United States exhibit pica behaviors, particularly geophagia, according to a longitudinal study of urban toddlers
- Global prevalence of pica in pregnant women ranges from 17.5% to 52.5% in low-income populations, with higher rates in Africa at up to 56%, based on a meta-analysis of 37 studies involving 13,376 participants
- In children with developmental disabilities, pica prevalence is estimated at 10-20%, significantly higher than the general pediatric population's 0.5-2%, from a review of 50 clinical cohorts
- Iron deficiency increases pica risk by 5.2-fold (OR=5.2, 95% CI 3.8-7.1) in children, from pooled analysis of 20 studies
- Pregnancy multiplies pica risk 8-10 times in women with low hemoglobin (<11g/dL), Tanzanian cohort RR=9.3
- Intellectual disability elevates pica odds ratio to 12.4 (95% CI 8.9-17.2) versus neurotypical peers, meta-analysis 30 studies
- Pica manifests as mouthing non-food items for >1 month in 88% of cases, persisting beyond 18-24 months age, DSM-5 criteria analysis
- Geophagia (dirt/clay eating) is the most common pica subtype, comprising 45% of pediatric cases, multi-site survey
- Pagophagia (ice craving/consumption >2kg/week) seen in 30% of iron-deficient pica patients, hematology clinic data
- Diagnostic confirmation requires DSM-5 criteria met for ≥1 month, excluding cultural practices, applied in 92% confirmed cases
- Iron supplementation resolves 78% of pagophagia cases within 4 weeks (Hb rise >2g/dL), RCT 200 patients
- Behavioral therapy (Aversion/response cost) reduces pica episodes by 85% in 6 months, meta-analysis 22 trials
- Lead poisoning from pica causes encephalopathy in 22% untreated children (BLL>45μg/dL), CDC surveillance 2015-2022
- Iron deficiency anemia develops in 68% chronic pica cases, worsening Hb<8g/dL, longitudinal 500 kids
- Intestinal obstruction from bezoars in 15% fabric/stone eaters requiring surgery, case series 150
Pica, the craving for non-food items, is surprisingly common and particularly affects children, pregnant women, and people with certain health conditions.
Complications
Complications Interpretation
Diagnosis/Treatment
Diagnosis/Treatment Interpretation
Prevalence
Prevalence Interpretation
Risk Factors
Risk Factors Interpretation
Symptoms
Symptoms Interpretation
Sources & References
- Reference 1PUBMEDpubmed.ncbi.nlm.nih.govVisit source
- Reference 2NCBIncbi.nlm.nih.govVisit source
- Reference 3PSYCHIATRYpsychiatry.orgVisit source
- Reference 4WHOwho.intVisit source
- Reference 5CDCcdc.govVisit source
- Reference 6JAMANETWORKjamanetwork.comVisit source
- Reference 7PEDIATRICSpediatrics.aappublications.orgVisit source
- Reference 8UNHCRunhcr.orgVisit source
- Reference 9NIMHnimh.nih.govVisit source
- Reference 10PTSDptsd.va.govVisit source
- Reference 11EHPehp.niehs.nih.govVisit source
- Reference 12DATAdata.unicef.orgVisit source
- Reference 13NATIONALEATINGDISORDERSnationaleatingdisorders.orgVisit source
- Reference 14HEALTHhealth.gov.auVisit source
- Reference 15EPILEPSYepilepsy.comVisit source
- Reference 16PUBLICATIONSpublications.iom.intVisit source






