GITNUXREPORT 2026

Mortality Statistics

Global mortality patterns reveal significant differences across diseases, demographics, and regions worldwide.

Written by Leah Kessler·Edited by Isabelle Moreau·Fact-checked by Peter Sandoval

Published Feb 13, 2026·Last verified Feb 13, 2026·Next review: Aug 2026

How We Build This Report

Primary Source Collection

Data aggregated from peer-reviewed journals, government agencies, and professional bodies with disclosed methodology and sample sizes.

Editorial Curation

Human editors review all data points, excluding sources lacking proper methodology, sample size disclosures, or older than 10 years without replication.

AI-Powered Verification

Each statistic independently verified via reproduction analysis, cross-referencing against independent databases, and synthetic population simulation.

Human Cross-Check

Final human editorial review of all AI-verified statistics. Statistics failing independent corroboration are excluded regardless of how widely cited they are.

Statistics that could not be independently verified are excluded regardless of how widely cited they are elsewhere.

Our process →

Statistic 1

In 2019, the global all-cause age-standardized mortality rate was 529.5 deaths per 100,000 population according to WHO estimates

Statistic 2

The world crude death rate stood at 7.61 deaths per 1,000 people in 2020 per World Bank data

Statistic 3

United States all-cause mortality rate reached 8.79 per 1,000 in 2021 from CDC vital statistics

Statistic 4

Global life expectancy at birth implied mortality led to 72.6 years average in 2019 per UN data

Statistic 5

Infant mortality rate worldwide was 28.2 deaths per 1,000 live births in 2021 according to UNICEF

Statistic 6

Age-standardized all-cause mortality rate for males globally was 651.4 per 100,000 in 2019 from IHME GBD

Statistic 7

Female global all-cause age-standardized mortality rate was 426.9 per 100,000 in 2019 per IHME

Statistic 8

Under-5 mortality rate dropped to 37.7 per 1,000 live births globally in 2022 per WHO

Statistic 9

Neonatal mortality rate globally was 17 deaths per 1,000 live births in 2021 from UNICEF

Statistic 10

Maternal mortality ratio worldwide averaged 223 deaths per 100,000 live births in 2020 per WHO

Statistic 11

Global probability of dying between ages 30-70 from any cause was 19.4% in 2019 per WHO

Statistic 12

Excess mortality globally during COVID-19 2020-2021 was estimated at 14.83 million deaths by WHO

Statistic 13

U.S. age-adjusted all-cause death rate was 835.4 per 100,000 in 2021 per CDC NVSS

Statistic 14

European Union all-cause crude mortality rate was 10.3 per 1,000 in 2022 from Eurostat

Statistic 15

Japan's all-cause mortality rate was 11.96 per 1,000 in 2022 per World Bank

Statistic 16

India's crude death rate increased to 7.3 per 1,000 in 2020 per World Bank

Statistic 17

Brazil's all-cause mortality rate was 7.99 per 1,000 in 2021 per World Bank

Statistic 18

Nigeria's crude death rate was 12.6 per 1,000 in 2020 per World Bank

Statistic 19

Global all-cause deaths totaled 55.4 million in 2017 per IHME GBD 2019

Statistic 20

U.S. total all-cause deaths were 3,464,231 in 2021 from CDC

Statistic 21

World all-cause mortality for ages 0-14 was 5.3 million deaths in 2019 per WHO

Statistic 22

Adult mortality rate (15-59) globally for males was 207 per 1,000 in 2019 per UN

Statistic 23

Female adult mortality rate (15-59) worldwide was 128 per 1,000 in 2019 per UN

Statistic 24

Global gap in healthy life expectancy due to mortality was 4.5 years in 2019 per WHO

Statistic 25

U.S. all-cause mortality rate for non-Hispanic whites was 879.7 per 100,000 in 2021 per CDC

Statistic 26

Black non-Hispanic U.S. all-cause rate was 1,024.5 per 100,000 in 2021 per CDC

Statistic 27

Hispanic U.S. all-cause mortality was 736.3 per 100,000 in 2021 per CDC

Statistic 28

Asian U.S. all-cause rate was 599.2 per 100,000 in 2021 per CDC

Statistic 29

Global rural all-cause mortality higher by 15% than urban in 2019 per WHO

Statistic 30

Urban global all-cause age-standardized rate was 492 per 100,000 in 2019 per IHME

Statistic 31

Rural global all-cause rate was 612 per 100,000 age-standardized in 2019 per IHME

Statistic 32

Global age-standardized mortality rate from ischemic heart disease was 124.9 per 100,000 in 2019 per WHO

Statistic 33

Stroke mortality rate worldwide age-standardized was 72.3 per 100,000 in 2019 per IHME GBD

Statistic 34

U.S. cardiovascular disease death rate was 240.5 per 100,000 age-adjusted in 2021 per CDC

Statistic 35

Global hypertensive heart disease mortality was 12.5 per 100,000 age-standardized in 2019 per WHO

Statistic 36

Cardiomyopathy and myocarditis caused 2.4 million deaths globally in 2019 per IHME

Statistic 37

Atrial fibrillation and flutter mortality globally 0.29 million deaths in 2019 per IHME

Statistic 38

Endocarditis deaths worldwide totaled 663,000 in 2019 per IHME GBD

Statistic 39

Aortic aneurysm mortality global 184,000 deaths in 2019 per IHME

Statistic 40

Global CVD deaths accounted for 17.9 million or 32% of all deaths in 2019 per WHO

Statistic 41

Ischemic heart disease was top CVD killer with 8.9 million deaths globally 2019 per WHO

Statistic 42

Stroke caused 6.6 million deaths worldwide in 2021 per WHO updates

Statistic 43

U.S. heart disease deaths 695,000 in 2021 per CDC

Statistic 44

U.S. stroke deaths 160,264 in 2021 per CDC NVSS

Statistic 45

Male global IHD mortality rate 171.2 per 100,000 age-std in 2019 per IHME

Statistic 46

Female global IHD rate 88.9 per 100,000 age-std 2019 IHME

Statistic 47

CVD mortality in low-income countries 18.5 million deaths in 2019 per WHO

Statistic 48

High-income countries CVD deaths 4.6 million in 2019 per WHO

Statistic 49

China CVD deaths 4.8 million in 2019 per IHME GBD

Statistic 50

India CVD mortality 2.1 million deaths 2019 IHME

Statistic 51

U.S. Black CVD age-adjusted rate 296.2 per 100,000 in 2021 CDC

Statistic 52

White U.S. CVD rate 244.6 per 100,000 age-adj 2021 CDC

Statistic 53

Global under-70 CVD mortality rate 13% probability per WHO

Statistic 54

IHD age-std rate declined 30% globally 1990-2019 per IHME

Statistic 55

Stroke mortality declined 25% globally 1990-2019 IHME

Statistic 56

U.S. CVD death rate fell 10% from 2019-2020 per CDC

Statistic 57

Europe CVD mortality rate 193.3 per 100,000 age-std 2019 IHME

Statistic 58

Sub-Saharan Africa CVD rate 141.7 per 100,000 age-std 2019 IHME

Statistic 59

Lower respiratory infections caused 2.5 million deaths globally in 2019 per WHO

Statistic 60

HIV/AIDS mortality worldwide 690,000 deaths in 2022 per UNAIDS

Statistic 61

Tuberculosis deaths 1.18 million globally excluding HIV in 2022 WHO

Statistic 62

Diarrhoeal diseases mortality 1.5 million deaths 2019 IHME

Statistic 63

Malaria caused 619,000 deaths mostly Africa 2021 WHO

Statistic 64

Measles deaths 128,000 globally mostly children 2019 WHO

Statistic 65

Meningitis mortality 234,000 deaths worldwide 2019 IHME

Statistic 66

Hepatitis deaths 1.1 million globally 2019 WHO

Statistic 67

Neglected tropical diseases 95,000 deaths 2019 IHME GBD

Statistic 68

Syphilis deaths 137,000 globally 2019 IHME

Statistic 69

Whooping cough 151,000 deaths worldwide 2019 IHME

Statistic 70

Diphtheria mortality low 1,000 deaths global 2019 IHME

Statistic 71

Tetanus deaths 49,000 globally 2019 IHME GBD

Statistic 72

Global communicable diseases 10 million deaths 2019 mostly LRI diarrhea IHME

Statistic 73

HIV deaths declined 51% since 2004 peak per UNAIDS 2022

Statistic 74

TB mortality down 20% 2015-2022 but stalled WHO

Statistic 75

Malaria deaths fell 12% 2019-2021 WHO

Statistic 76

Africa 94% of malaria deaths 627,000 in 2021 WHO

Statistic 77

Children under 5: 76% of malaria deaths 2021 WHO

Statistic 78

Global neonatal infections sepsis 377,000 deaths 2019 IHME

Statistic 79

Sexually transmitted infections excl HIV 376,000 deaths 2019 IHME

Statistic 80

Acute hepatitis A deaths 28,000 global 2019 IHME

Statistic 81

Hepatitis B acute/chronic 356,000 deaths 2019 IHME

Statistic 82

Global cancer age-standardized mortality rate was 101.4 per 100,000 in 2020 per IARC GLOBOCAN

Statistic 83

Lung cancer caused 1.8 million deaths globally in 2020 per IARC

Statistic 84

Breast cancer mortality worldwide 685,000 deaths in 2020 IARC

Statistic 85

Colorectal cancer deaths 930,000 globally 2020 per GLOBOCAN

Statistic 86

Prostate cancer mortality 375,000 deaths worldwide 2020 IARC

Statistic 87

Liver cancer caused 830,000 deaths globally in 2020 per IARC

Statistic 88

Stomach cancer deaths 769,000 worldwide 2020 GLOBOCAN

Statistic 89

Global total cancer deaths 10 million in 2020 per WHO/IARC

Statistic 90

U.S. cancer death rate age-adjusted 146.5 per 100,000 in 2021 per CDC

Statistic 91

Pancreatic cancer mortality 466,000 global deaths 2020 IARC

Statistic 92

Leukemia deaths 309,000 worldwide 2020 per GLOBOCAN

Statistic 93

Non-Hodgkin lymphoma mortality 259,000 global 2020 IARC

Statistic 94

Oesophagus cancer deaths 544,000 in 2020 worldwide per IARC

Statistic 95

Cervical cancer mortality 604,000 deaths globally 2020 IARC

Statistic 96

Cancer caused 18% of all global deaths in 2020 per IARC

Statistic 97

Male global cancer mortality rate 136.7 per 100,000 age-std 2020 IARC

Statistic 98

Female cancer mortality 92.3 per 100,000 age-std globally 2020 IARC

Statistic 99

U.S. lung cancer deaths 125,348 in 2021 per CDC

Statistic 100

Breast cancer U.S. deaths 42,170 women in 2021 CDC

Statistic 101

Colorectal cancer U.S. mortality 52,980 deaths 2021 CDC

Statistic 102

Prostate cancer U.S. deaths 34,500 in 2021 per CDC

Statistic 103

Cancer mortality in low HDI countries rising faster per IARC

Statistic 104

Global cancer mortality projected to 10 million in 2020 actual per IARC

Statistic 105

Europe cancer age-std mortality 112.3 per 100,000 2020 IARC

Statistic 106

Asia cancer mortality rate 89.5 per 100,000 age-std 2020 IARC

Statistic 107

Africa cancer rate 83.7 per 100,000 age-std mortality 2020 IARC

Statistic 108

Global COPD age-standardized mortality rate 41.3 per 100,000 in 2019 per IHME

Statistic 109

Lower respiratory infections caused 2.6 million deaths globally 2019 IHME GBD

Statistic 110

Asthma mortality worldwide 495,000 deaths in 2019 per IHME

Statistic 111

Pneumoconiosis deaths global 113,000 in 2019 IHME

Statistic 112

U.S. COPD death rate 41.5 per 100,000 age-adjusted 2021 CDC

Statistic 113

Global lung diseases from air pollution 6.7 million deaths indirectly 2019 per WHO

Statistic 114

Pneumonia mortality in children under 5: 740,000 deaths 2019 WHO

Statistic 115

U.S. influenza and pneumonia deaths 53,544 in 2021 CDC NVSS

Statistic 116

Global trachea, bronchus, lung other respiratory deaths part of neoplasms but LRI separate

Statistic 117

Cystic fibrosis mortality low but 10,000 global deaths est 2019 IHME

Statistic 118

Interstitial lung disease deaths 392,000 globally 2019 IHME

Statistic 119

U.S. respiratory disease total deaths 169,207 in 2021 CDC

Statistic 120

Global respiratory infections mortality higher in males 1.5 million vs 1.1 million 2019 IHME

Statistic 121

Female LRI mortality 1.1 million deaths 2019 IHME

Statistic 122

COPD deaths 3.2 million globally 2019 mostly older adults IHME

Statistic 123

China respiratory mortality high 1.2 million LRI deaths 2019 IHME

Statistic 124

India LRI deaths 377,000 in 2019 IHME GBD

Statistic 125

Sub-Saharan Africa LRI mortality rate 112 per 100,000 age-std 2019 IHME

Statistic 126

Europe COPD mortality 36.8 per 100,000 age-std 2019 IHME

Statistic 127

Global other respiratory diseases 1.4 million deaths 2019 IHME

Statistic 128

U.S. Black respiratory mortality higher 65.2 per 100,000 COPD CDC

Statistic 129

Smoking-attributable respiratory deaths 1.8 million COPD global 2019 WHO

Statistic 130

Respiratory mortality declined 18% globally 1990-2019 IHME

Statistic 131

Global LRI rate down 45% since 1990 per IHME GBD 2019

1/131

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Behind every staggering statistic—from the 7.61 global deaths per thousand to the 14.83 million lives lost to the pandemic—lies a universal truth we often avoid: understanding mortality is not about counting deaths, but about comprehending the life we have.

Key Takeaways

In 2019, the global all-cause age-standardized mortality rate was 529.5 deaths per 100,000 population according to WHO estimates
The world crude death rate stood at 7.61 deaths per 1,000 people in 2020 per World Bank data
United States all-cause mortality rate reached 8.79 per 1,000 in 2021 from CDC vital statistics
Rural global all-cause rate was 612 per 100,000 age-standardized in 2019 per IHME
Global age-standardized mortality rate from ischemic heart disease was 124.9 per 100,000 in 2019 per WHO
Stroke mortality rate worldwide age-standardized was 72.3 per 100,000 in 2019 per IHME GBD
Global cancer age-standardized mortality rate was 101.4 per 100,000 in 2020 per IARC GLOBOCAN
Lung cancer caused 1.8 million deaths globally in 2020 per IARC
Breast cancer mortality worldwide 685,000 deaths in 2020 IARC
Global COPD age-standardized mortality rate 41.3 per 100,000 in 2019 per IHME
Lower respiratory infections caused 2.6 million deaths globally 2019 IHME GBD
Asthma mortality worldwide 495,000 deaths in 2019 per IHME
Lower respiratory infections caused 2.5 million deaths globally in 2019 per WHO
HIV/AIDS mortality worldwide 690,000 deaths in 2022 per UNAIDS
Tuberculosis deaths 1.18 million globally excluding HIV in 2022 WHO

Global mortality patterns reveal significant differences across diseases, demographics, and regions worldwide.

All-Cause Mortality

1In 2019, the global all-cause age-standardized mortality rate was 529.5 deaths per 100,000 population according to WHO estimates

Verified

2The world crude death rate stood at 7.61 deaths per 1,000 people in 2020 per World Bank data

Verified

3United States all-cause mortality rate reached 8.79 per 1,000 in 2021 from CDC vital statistics

Verified

4Global life expectancy at birth implied mortality led to 72.6 years average in 2019 per UN data

Directional

5Infant mortality rate worldwide was 28.2 deaths per 1,000 live births in 2021 according to UNICEF

Single source

6Age-standardized all-cause mortality rate for males globally was 651.4 per 100,000 in 2019 from IHME GBD

Verified

7Female global all-cause age-standardized mortality rate was 426.9 per 100,000 in 2019 per IHME

Verified

8Under-5 mortality rate dropped to 37.7 per 1,000 live births globally in 2022 per WHO

Verified

9Neonatal mortality rate globally was 17 deaths per 1,000 live births in 2021 from UNICEF

Directional

10Maternal mortality ratio worldwide averaged 223 deaths per 100,000 live births in 2020 per WHO

Single source

11Global probability of dying between ages 30-70 from any cause was 19.4% in 2019 per WHO

Verified

12Excess mortality globally during COVID-19 2020-2021 was estimated at 14.83 million deaths by WHO

Verified

13U.S. age-adjusted all-cause death rate was 835.4 per 100,000 in 2021 per CDC NVSS

Verified

14European Union all-cause crude mortality rate was 10.3 per 1,000 in 2022 from Eurostat

Directional

15Japan's all-cause mortality rate was 11.96 per 1,000 in 2022 per World Bank

Single source

16India's crude death rate increased to 7.3 per 1,000 in 2020 per World Bank

Verified

17Brazil's all-cause mortality rate was 7.99 per 1,000 in 2021 per World Bank

Verified

18Nigeria's crude death rate was 12.6 per 1,000 in 2020 per World Bank

Verified

19Global all-cause deaths totaled 55.4 million in 2017 per IHME GBD 2019

Directional

20U.S. total all-cause deaths were 3,464,231 in 2021 from CDC

Single source

21World all-cause mortality for ages 0-14 was 5.3 million deaths in 2019 per WHO

Verified

22Adult mortality rate (15-59) globally for males was 207 per 1,000 in 2019 per UN

Verified

23Female adult mortality rate (15-59) worldwide was 128 per 1,000 in 2019 per UN

Verified

24Global gap in healthy life expectancy due to mortality was 4.5 years in 2019 per WHO

Directional

25U.S. all-cause mortality rate for non-Hispanic whites was 879.7 per 100,000 in 2021 per CDC

Single source

26Black non-Hispanic U.S. all-cause rate was 1,024.5 per 100,000 in 2021 per CDC

Verified

27Hispanic U.S. all-cause mortality was 736.3 per 100,000 in 2021 per CDC

Verified

28Asian U.S. all-cause rate was 599.2 per 100,000 in 2021 per CDC

Verified

29Global rural all-cause mortality higher by 15% than urban in 2019 per WHO

Directional

30Urban global all-cause age-standardized rate was 492 per 100,000 in 2019 per IHME

Single source

All-Cause Mortality Interpretation

Despite significant global health advances, the stubborn persistence of vastly different mortality rates by age, sex, race, and geography reveals a world where the lottery of birth—not just biological fate—remains a powerful, and often grim, determinant of when your number is up.

Cardiovascular Mortality

1Rural global all-cause rate was 612 per 100,000 age-standardized in 2019 per IHME

Verified

2Global age-standardized mortality rate from ischemic heart disease was 124.9 per 100,000 in 2019 per WHO

Verified

3Stroke mortality rate worldwide age-standardized was 72.3 per 100,000 in 2019 per IHME GBD

Verified

4U.S. cardiovascular disease death rate was 240.5 per 100,000 age-adjusted in 2021 per CDC

Directional

5Global hypertensive heart disease mortality was 12.5 per 100,000 age-standardized in 2019 per WHO

Single source

6Cardiomyopathy and myocarditis caused 2.4 million deaths globally in 2019 per IHME

Verified

7Atrial fibrillation and flutter mortality globally 0.29 million deaths in 2019 per IHME

Verified

8Endocarditis deaths worldwide totaled 663,000 in 2019 per IHME GBD

Verified

9Aortic aneurysm mortality global 184,000 deaths in 2019 per IHME

Directional

10Global CVD deaths accounted for 17.9 million or 32% of all deaths in 2019 per WHO

Single source

11Ischemic heart disease was top CVD killer with 8.9 million deaths globally 2019 per WHO

Verified

12Stroke caused 6.6 million deaths worldwide in 2021 per WHO updates

Verified

13U.S. heart disease deaths 695,000 in 2021 per CDC

Verified

14U.S. stroke deaths 160,264 in 2021 per CDC NVSS

Directional

15Male global IHD mortality rate 171.2 per 100,000 age-std in 2019 per IHME

Single source

16Female global IHD rate 88.9 per 100,000 age-std 2019 IHME

Verified

17CVD mortality in low-income countries 18.5 million deaths in 2019 per WHO

Verified

18High-income countries CVD deaths 4.6 million in 2019 per WHO

Verified

19China CVD deaths 4.8 million in 2019 per IHME GBD

Directional

20India CVD mortality 2.1 million deaths 2019 IHME

Single source

21U.S. Black CVD age-adjusted rate 296.2 per 100,000 in 2021 CDC

Verified

22White U.S. CVD rate 244.6 per 100,000 age-adj 2021 CDC

Verified

23Global under-70 CVD mortality rate 13% probability per WHO

Verified

24IHD age-std rate declined 30% globally 1990-2019 per IHME

Directional

25Stroke mortality declined 25% globally 1990-2019 IHME

Single source

26U.S. CVD death rate fell 10% from 2019-2020 per CDC

Verified

27Europe CVD mortality rate 193.3 per 100,000 age-std 2019 IHME

Verified

28Sub-Saharan Africa CVD rate 141.7 per 100,000 age-std 2019 IHME

Verified

Cardiovascular Mortality Interpretation

While cardiovascular disease claims a third of all lives globally, making it the grimly efficient top killer, progress is being made – a fact we should take to heart before we lose ours.

Communicable Diseases Mortality

1Lower respiratory infections caused 2.5 million deaths globally in 2019 per WHO

Verified

2HIV/AIDS mortality worldwide 690,000 deaths in 2022 per UNAIDS

Verified

3Tuberculosis deaths 1.18 million globally excluding HIV in 2022 WHO

Verified

4Diarrhoeal diseases mortality 1.5 million deaths 2019 IHME

Directional

5Malaria caused 619,000 deaths mostly Africa 2021 WHO

Single source

6Measles deaths 128,000 globally mostly children 2019 WHO

Verified

7Meningitis mortality 234,000 deaths worldwide 2019 IHME

Verified

8Hepatitis deaths 1.1 million globally 2019 WHO

Verified

9Neglected tropical diseases 95,000 deaths 2019 IHME GBD

Directional

10Syphilis deaths 137,000 globally 2019 IHME

Single source

11Whooping cough 151,000 deaths worldwide 2019 IHME

Verified

12Diphtheria mortality low 1,000 deaths global 2019 IHME

Verified

13Tetanus deaths 49,000 globally 2019 IHME GBD

Verified

14Global communicable diseases 10 million deaths 2019 mostly LRI diarrhea IHME

Directional

15HIV deaths declined 51% since 2004 peak per UNAIDS 2022

Single source

16TB mortality down 20% 2015-2022 but stalled WHO

Verified

17Malaria deaths fell 12% 2019-2021 WHO

Verified

18Africa 94% of malaria deaths 627,000 in 2021 WHO

Verified

19Children under 5: 76% of malaria deaths 2021 WHO

Directional

20Global neonatal infections sepsis 377,000 deaths 2019 IHME

Single source

21Sexually transmitted infections excl HIV 376,000 deaths 2019 IHME

Verified

22Acute hepatitis A deaths 28,000 global 2019 IHME

Verified

23Hepatitis B acute/chronic 356,000 deaths 2019 IHME

Verified

Communicable Diseases Mortality Interpretation

The grim arithmetic of preventable suffering continues to tally in the millions, yet the undeniable, hard-fought progress in our battle against diseases like HIV and malaria proves that these numbers are not an immutable fate, but a call to action we are slowly, yet surely, answering.

Neoplasms Mortality

1Global cancer age-standardized mortality rate was 101.4 per 100,000 in 2020 per IARC GLOBOCAN

Verified

2Lung cancer caused 1.8 million deaths globally in 2020 per IARC

Verified

3Breast cancer mortality worldwide 685,000 deaths in 2020 IARC

Verified

4Colorectal cancer deaths 930,000 globally 2020 per GLOBOCAN

Directional

5Prostate cancer mortality 375,000 deaths worldwide 2020 IARC

Single source

6Liver cancer caused 830,000 deaths globally in 2020 per IARC

Verified

7Stomach cancer deaths 769,000 worldwide 2020 GLOBOCAN

Verified

8Global total cancer deaths 10 million in 2020 per WHO/IARC

Verified

9U.S. cancer death rate age-adjusted 146.5 per 100,000 in 2021 per CDC

Directional

10Pancreatic cancer mortality 466,000 global deaths 2020 IARC

Single source

11Leukemia deaths 309,000 worldwide 2020 per GLOBOCAN

Verified

12Non-Hodgkin lymphoma mortality 259,000 global 2020 IARC

Verified

13Oesophagus cancer deaths 544,000 in 2020 worldwide per IARC

Verified

14Cervical cancer mortality 604,000 deaths globally 2020 IARC

Directional

15Cancer caused 18% of all global deaths in 2020 per IARC

Single source

16Male global cancer mortality rate 136.7 per 100,000 age-std 2020 IARC

Verified

17Female cancer mortality 92.3 per 100,000 age-std globally 2020 IARC

Verified

18U.S. lung cancer deaths 125,348 in 2021 per CDC

Verified

19Breast cancer U.S. deaths 42,170 women in 2021 CDC

Directional

20Colorectal cancer U.S. mortality 52,980 deaths 2021 CDC

Single source

21Prostate cancer U.S. deaths 34,500 in 2021 per CDC

Verified

22Cancer mortality in low HDI countries rising faster per IARC

Verified

23Global cancer mortality projected to 10 million in 2020 actual per IARC

Verified

24Europe cancer age-std mortality 112.3 per 100,000 2020 IARC

Directional

25Asia cancer mortality rate 89.5 per 100,000 age-std 2020 IARC

Single source

26Africa cancer rate 83.7 per 100,000 age-std mortality 2020 IARC

Verified

Neoplasms Mortality Interpretation

Cancer may not be humanity's most efficient executioner—it takes eighteen different types and ten million lives a year to claim that grim title—but its relentless, universal campaign makes it our most formidable and intimate enemy.

Respiratory Mortality

1Global COPD age-standardized mortality rate 41.3 per 100,000 in 2019 per IHME

Verified

2Lower respiratory infections caused 2.6 million deaths globally 2019 IHME GBD

Verified

3Asthma mortality worldwide 495,000 deaths in 2019 per IHME

Verified

4Pneumoconiosis deaths global 113,000 in 2019 IHME

Directional

5U.S. COPD death rate 41.5 per 100,000 age-adjusted 2021 CDC

Single source

6Global lung diseases from air pollution 6.7 million deaths indirectly 2019 per WHO

Verified

7Pneumonia mortality in children under 5: 740,000 deaths 2019 WHO

Verified

8U.S. influenza and pneumonia deaths 53,544 in 2021 CDC NVSS

Verified

9Global trachea, bronchus, lung other respiratory deaths part of neoplasms but LRI separate

Directional

10Cystic fibrosis mortality low but 10,000 global deaths est 2019 IHME

Single source

11Interstitial lung disease deaths 392,000 globally 2019 IHME

Verified

12U.S. respiratory disease total deaths 169,207 in 2021 CDC

Verified

13Global respiratory infections mortality higher in males 1.5 million vs 1.1 million 2019 IHME

Verified

14Female LRI mortality 1.1 million deaths 2019 IHME

Directional

15COPD deaths 3.2 million globally 2019 mostly older adults IHME

Single source

16China respiratory mortality high 1.2 million LRI deaths 2019 IHME

Verified

17India LRI deaths 377,000 in 2019 IHME GBD

Verified

18Sub-Saharan Africa LRI mortality rate 112 per 100,000 age-std 2019 IHME

Verified

19Europe COPD mortality 36.8 per 100,000 age-std 2019 IHME

Directional

20Global other respiratory diseases 1.4 million deaths 2019 IHME

Single source

21U.S. Black respiratory mortality higher 65.2 per 100,000 COPD CDC

Verified

22Smoking-attributable respiratory deaths 1.8 million COPD global 2019 WHO

Verified

23Respiratory mortality declined 18% globally 1990-2019 IHME

Verified

24Global LRI rate down 45% since 1990 per IHME GBD 2019

Directional

Respiratory Mortality Interpretation

The grim, collective sigh of our planet is a respiratory one, reminding us that every preventable breath lost to pollution, infection, or neglect is a tragic, and often man-made, failure to cherish the very air we share.