Gitnux/Report 2026

Endometriosis Statistics

From 75% endometriosis confirmation on laparoscopy to ultrasound sensitivity reaching 90 to 95% for endometriomas, these 2025 to 2026 ready diagnostics and treatment outcomes help you see why symptoms often get missed and how relief can follow. Learn how endometriosis affects about 190 million people worldwide and can drive up costs like US out-of-pocket expenses of $12,000 a year, alongside real-world symptom burdens and the therapies that reduce pain, shrink lesions, or calm flare ups.
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Endometriosis Statistics
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Next review Jan 2027
Endometriosis affects about 190 million women and girls worldwide, and around 10% of people who menstruate are impacted during reproductive age. Even when symptoms seem clear, the tests can tell very different stories, with laparoscopy confirming endometriosis in 75% of suspected cases while ultrasound finds endometriomas with 90 to 95% sensitivity. This mix of detection rates, symptom burdens, and treatment responses is exactly why the numbers are worth comparing side by side.

Key Takeaways

  • Laparoscopy confirms endometriosis in 75% of suspected symptomatic cases.
  • Transvaginal ultrasound detects endometriomas with 90-95% sensitivity.
  • MRI sensitivity for deep infiltrating endometriosis is 85-95%.
  • Endometriosis affects approximately 190 million women and girls globally, representing about 10% of the world's female population of reproductive age.
  • In the United States, endometriosis is estimated to affect 11% of women aged 15-44, equating to roughly 6.5 million women.
  • The prevalence of endometriosis in women undergoing laparoscopy for infertility is around 30-50%.
  • Endometriosis costs US patients $12,000 annually in out-of-pocket expenses.
  • Women with endometriosis lose 10.8 hours/week to symptoms.
  • 54% of patients report job loss or reduced hours due to disease.
  • 85-95% of women with endometriosis experience dysmenorrhea.
  • Chronic pelvic pain affects 70-90% of endometriosis patients.
  • Dyspareunia (painful intercourse) is reported by 50-60% of women with endometriosis.
  • Hormonal contraceptives provide pain relief in 70-80% initially.
  • Laparoscopic excision reduces pain by 50-70% at 6 months.
  • GnRH agonists achieve 80-90% symptom remission short-term.

Endometriosis affects 190 million people worldwide, and diagnosis and relief can be guided by key imaging findings and therapies.

01 · Category

Diagnosis23 stats

01
Laparoscopy confirms endometriosis in 75% of suspected symptomatic cases.
02
Transvaginal ultrasound detects endometriomas with 90-95% sensitivity.
03
MRI sensitivity for deep infiltrating endometriosis is 85-95%.
04
CA-125 levels are elevated in 40-80% of advanced cases.
05
Rectal endoscopic sonography has 98% accuracy for bowel involvement.
06
Average diagnostic delay is 7-10 years from symptom onset.
07
Only 46% of patients are diagnosed within 5 years of symptoms.
08
Pelvic exam detects abnormalities in 50-60% of cases.
09
Ultrasound detects deep nodules with 70-90% sensitivity using TVS.
10
Histological confirmation required in 100% for definitive diagnosis.
11
20-30% of laparoscopies for pain yield incidental endometriosis.
12
Blood tests like CA-125 have 20% sensitivity in minimal disease.
13
Symptom-based questionnaires like EPQ have 85% specificity.
14
3D ultrasound improves detection of pouch of Douglas obliteration to 92%.
15
Only 18% of GPs consider endometriosis in first visit for pain.
16
Diffusion-weighted MRI enhances nodule detection to 95% accuracy.
17
Urine biomarkers like VEGF show promise with 80% sensitivity in trials.
18
ASRM staging correlates poorly with pain (r=0.1-0.2).
19
65% of patients see 5+ doctors before diagnosis.
20
Bowel endometriosis diagnosed preop in 70% via TVUS/ MRI combo.
21
Adolescent diagnosis via laparoscopy shows 70% stage I/II.
22
CA-19-9 elevated in 50% with bowel involvement.
23
Empirical treatment response predicts diagnosis in 60-70%.
Interpretation

Diagnosis Interpretation

From a diagnosis perspective, imaging and laparoscopy often miss or only partially confirm disease early on, since laparoscopy confirms it in 75% of suspected cases while the diagnostic journey averages 7 to 10 years from symptom onset.

02 · Category

Epidemiology26 stats

01
Endometriosis affects approximately 190 million women and girls globally, representing about 10% of the world's female population of reproductive age.
02
In the United States, endometriosis is estimated to affect 11% of women aged 15-44, equating to roughly 6.5 million women.
03
The prevalence of endometriosis in women undergoing laparoscopy for infertility is around 30-50%.
04
Endometriosis is found in 25-40% of infertile women and 70-80% of those with chronic pelvic pain.
05
Among adolescents with chronic pelvic pain, up to 62% are diagnosed with endometriosis via laparoscopy.
06
Black women have a 36% lower likelihood of receiving a timely endometriosis diagnosis compared to white women.
07
The incidence of endometriosis has increased by 67% in the UK from 1995 to 2017.
08
Endometriosis accounts for 25-50% of all infertility cases in women.
09
In Australia, 1 in 10 women aged 14-49 have endometriosis, affecting over 737,000 women.
10
The global economic burden of endometriosis is estimated at $69.4 billion annually in direct and indirect costs.
11
Endometriosis is diagnosed in 5-15% of women undergoing tubal ligation.
12
Familial risk increases the odds of endometriosis by 5-8 times if a first-degree relative is affected.
13
In Europe, the prevalence among reproductive-age women is 5-10%.
14
Endometriosis lesions are classified into superficial peritoneal (80-90% of cases), ovarian endometriomas (17-44%), and deep infiltrating (5-12%).
15
The lifetime risk of endometriosis surgery in Sweden is 11% for women born 1960-1989.
16
In China, endometriosis prevalence in pelvic laparoscopies is 15-20%.
17
Endometriosis is more common in urban areas, with a 1.5-fold higher diagnosis rate than rural.
18
Among women with endometriosis, 40-60% also have adenomyosis.
19
The disease is diagnosed 6.7 years on average after symptom onset.
20
Endometriosis affects 176 million women worldwide as per 2011 estimates.
21
In Japan, deep endometriosis prevalence is 20-40% in surgical cases.
22
Nulliparity increases endometriosis risk by 30-50%.
23
The condition is found in 1-7% of asymptomatic women at autopsy or surgery.
24
In the US, annual healthcare costs for endometriosis exceed $22 billion.
25
Endometriosis prevalence in teenagers with dysmenorrhea is 45-75%.
26
Global variation shows higher rates in developed countries (up to 15%).
Interpretation

Epidemiology Interpretation

From an epidemiology standpoint, endometriosis is widespread, affecting about 190 million women and girls globally and roughly 10% of the female population, yet diagnosis is uneven, with Black women 36% less likely than white women to receive timely care.

03 · Category

Impact20 stats

01
Endometriosis costs US patients $12,000annually in out-of-pocket expenses.
02
Women with endometriosis lose 10.8 hours/week to symptoms.
03
54% of patients report job loss or reduced hours due to disease.
04
Absenteeism from work averages 11 hours/month.
05
Quality of life scores (SF-36) are 50% lower than controls.
06
70% experience sexual dysfunction impacting relationships.
07
Annual productivity loss per patient $15,160in direct costs.
08
40% have anxiety disorders, 30% depression.
09
Fertility treatments cost average $20,000-50,000 per patient.
10
25% of patients consider suicide due to pain.
11
Global DALYs lost to endometriosis: 0.856 million annually.
12
Relationship breakdown in 38% of cases.
13
Opioid prescriptions 3-fold higher, addiction risk 2x.
14
Education disruption in 50% of adolescents.
15
Healthcare utilization 6x higher than average women.
16
60% report financial hardship from treatments.
17
Pain catastrophizing scores 2x higher, worsening QoL.
18
80% have reduced exercise capacity due to fatigue.
19
Ovarian reserve diminished, AMH 25% lower.
20
Bowel obstruction risk 1-3% lifetime.
Interpretation

Impact Interpretation

For the impact category, the numbers show endometriosis severely disrupts everyday life, costing US patients $12,000 a year out of pocket and taking 10.8 hours each week while 54% report job loss or reduced hours and absenteeism averages 11 hours per month.

04 · Category

Symptoms24 stats

01
85-95% of women with endometriosis experience dysmenorrhea.
02
Chronic pelvic pain affects 70-90% of endometriosis patients.
03
Dyspareunia (painful intercourse) is reported by 50-60% of women with endometriosis.
04
Non-menstrual pelvic pain occurs in 30-50% of cases daily or weekly.
05
Dyschezia (painful bowel movements) is present in 20-50% of patients.
06
30-50% of women with endometriosis experience bloating and gastrointestinal symptoms.
07
Fatigue is reported by 75-90% of endometriosis patients.
08
Infertility affects 30-50% of women with the disease.
09
Menorrhagia (heavy periods) occurs in 40-60% of cases.
10
Back pain or radiating leg pain is noted in 30% of patients.
11
Nausea and vomiting during menses affect 20-40%.
12
Urinary symptoms like frequency or pain occur in 10-20%.
13
Headaches and migraines are 2-3 times more common in endometriosis patients.
14
Depression and anxiety prevalence is 40-60% higher than general population.
15
Adnexal tenderness on exam in 80% of cases.
16
Uterosacral ligament nodularity in 50% of deep endometriosis.
17
Shoulder tip pain from diaphragmatic endometriosis in 1-5%.
18
Pain worsens over time in 80% of untreated patients.
19
Cyclic pain patterns in 70% correlating with menstrual cycle.
20
90% of women report pain impacting daily activities.
21
Sleep disturbances in 50-70% due to pain.
22
25-40% experience pain with ovulation.
23
Rectovaginal pain in 10-20% with deep infiltrating disease.
24
Average pain score on VAS is 7.2/10 for pelvic pain in patients.
Interpretation

Symptoms Interpretation

Within the symptoms category, most people with endometriosis report recurring pain, with 85 to 95% experiencing dysmenorrhea and 70 to 90% suffering chronic pelvic pain, and many also deal with additional symptoms like GI issues affecting 30 to 50%.

05 · Category

Treatment20 stats

01
Hormonal contraceptives provide pain relief in 70-80% initially.
02
Laparoscopic excision reduces pain by 50-70% at 6 months.
03
GnRH agonists achieve 80-90% symptom remission short-term.
04
Progestins like dienogest reduce lesions by 30-50%.
05
Hysterectomy with oophorectomy cures 80-90% of cases.
06
NSAIDs relieve pain in 50-60% of mild cases.
07
Elagolix (Orilissa) reduces dysmenorrhea by 75% in phase 3 trials.
08
Recurrence rate post-laparoscopy is 20-40% at 5 years.
09
IUD with levonorgestrel reduces bleeding by 90%.
10
Aromatase inhibitors adjunctive therapy improves pain in 60% refractory cases.
11
Combined oral contraceptives suppress symptoms in 70-80%.
12
Deep infiltrating disease requires multidisciplinary surgery in 90% for optimal outcomes.
13
Physiotherapy pelvic floor therapy benefits 60-70% for pain.
14
Danazol effective but 50% side effect dropout rate.
15
IVF success rates 40-50% per cycle in endometriotic infertility.
16
Add-back therapy with GnRH reduces bone loss to <2%.
17
Laparotomy needed in 10-20% for severe adhesions.
18
Acupuncture shows 50% pain reduction in meta-analyses.
19
40% of patients require repeat surgery within 5 years.
20
Dietary interventions like low FODMAP reduce GI symptoms by 60%.
Interpretation

Treatment Interpretation

Treatment for endometriosis shows generally strong early symptom control, with hormonal contraceptives helping 70 to 80% initially and GnRH agonists reaching 80 to 90% short term remission, though procedure based options tend to reduce pain more gradually such as laparoscopic excision cutting pain by 50 to 70% at 6 months.
report visual · Breakdown

Endometriosis: diagnosis & symptom impact at a glance

Most suspected cases are confirmed with laparoscopy, while nearly all patients report pain that disrupts daily life—highlighting both diagnostic needs and the burden of symptoms.

75%
Laparoscopy confirms endometriosis in 75% of suspected symptomatic cases.
25%
25% of patients consider suicide due to pain.
Reference

Cite This Report

This report is designed to be cited. We maintain stable URLs and versioned verification dates. Copy the format appropriate for your publication below.

APA
Nathan Caldwell. (2026, February 13). Endometriosis Statistics. Gitnux. https://gitnux.org/endometriosis-statistics
MLA
Nathan Caldwell. "Endometriosis Statistics." Gitnux, 13 Feb 2026, https://gitnux.org/endometriosis-statistics.
Chicago
Nathan Caldwell. 2026. "Endometriosis Statistics." Gitnux. https://gitnux.org/endometriosis-statistics.