Key Takeaways
- In 2020, colorectal cancer was the third most common cancer worldwide with approximately 1.93 million new cases, representing 10.0% of all cancer cases
- Globally, colorectal cancer ranks as the second leading cause of cancer death with 935,000 deaths in 2020, accounting for 9.3% of all cancer deaths
- In the United States, an estimated 153,020 new cases of colorectal cancer are expected to be diagnosed in 2024
- Age is the biggest risk factor with 90% of colorectal cancers diagnosed in people over 50 worldwide
- Family history increases colorectal cancer risk 2-3 fold if a first-degree relative is affected before age 50
- Inflammatory bowel disease like ulcerative colitis raises lifetime colorectal cancer risk to 30% after 35 years
- Change in bowel habits occurs in 75% of colorectal cancer patients
- Blood in stool is reported in 40-60% of colorectal cancer cases at diagnosis
- Abdominal pain or cramping present in 50-70% of patients with colon cancer
- 5-year survival for localized colorectal cancer is 91%
- Regional spread colorectal cancer 5-year survival 73%
- Distant metastatic colorectal cancer 5-year survival 15%
- Colorectal cancer screening reduces mortality by 30-50% in screened populations
- Colonoscopy every 10 years from age 45 reduces colorectal cancer incidence by 68% and mortality by 53%
- FIT annual screening detects 75% of colorectal cancers, reduces mortality by 33%
A common deadly cancer's burden is rising despite effective screening and prevention.
Incidence & Prevalence
Incidence & Prevalence Interpretation
Prevention & Screening
Prevention & Screening Interpretation
Risk Factors
Risk Factors Interpretation
Symptoms & Diagnosis
Symptoms & Diagnosis Interpretation
Treatment & Survival
Treatment & Survival Interpretation
Sources & References
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- Reference 2CANCERcancer.orgVisit source
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- Reference 6GCOgco.iarc.who.intVisit source
- Reference 7PUBMEDpubmed.ncbi.nlm.nih.govVisit source
- Reference 8CDCcdc.govVisit source
- Reference 9GANJOHOganjoho.jpVisit source
- Reference 10SEERseer.cancer.govVisit source
- Reference 11CANCERcancer.caVisit source
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- Reference 14WCRFwcrf.orgVisit source
- Reference 15GENOMEgenome.govVisit source
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- Reference 18NHSnhs.ukVisit source
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- Reference 20WEBMDwebmd.comVisit source
- Reference 21RADIOLOGYINFOradiologyinfo.orgVisit source
- Reference 22ASGEasge.orgVisit source
- Reference 23NCBIncbi.nlm.nih.govVisit source
- Reference 24MACMILLANmacmillan.org.ukVisit source
- Reference 25NCCNnccn.orgVisit source






