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Science Research

Top 10 Best Sample Tracking Software of 2026

Explore top sample tracking software solutions to streamline labs. Compare features, find the best fit, and optimize sample management today.

Alexander Schmidt

Alexander Schmidt

Feb 11, 2026

10 tools comparedExpert reviewed
Independent evaluation · Unbiased commentary · Updated regularly
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Accurate sample tracking is foundational to modern lab operations, directly impacting efficiency, compliance, and data reliability. With a range of tools available to streamline workflows, selecting the right software is critical—this guide highlights the 10 leading solutions to help users navigate their options.

Quick Overview

  1. 1#1: Benchling - Cloud-based platform for tracking and managing biological samples, workflows, and data in biotech R&D.
  2. 2#2: LabWare LIMS - Comprehensive LIMS for full lifecycle sample tracking, management, and compliance across labs.
  3. 3#3: STARLIMS - Flexible LIMS solution for efficient sample tracking, workflow automation, and regulatory compliance.
  4. 4#4: Thermo Fisher SampleManager - Integrated LIMS with advanced sample management and seamless instrument connectivity.
  5. 5#5: LabVantage - End-to-end LIMS platform for robust sample tracking and laboratory informatics.
  6. 6#6: CoreLIMS - Modular LIMS for streamlined sample lifecycle management and data integrity.
  7. 7#7: Sapio LIMS - Unified lab platform with intelligent sample tracking and assay data management.
  8. 8#8: CloudLIMS - Cloud-based LIMS for cost-effective sample tracking and collaboration in labs.
  9. 9#9: Labguru - All-in-one ELN and LIMS for research sample inventory and experiment tracking.
  10. 10#10: SciNote - Electronic lab notebook with integrated sample management and tracking features.

Tools were chosen and ranked based on features like lifecycle management, integration capabilities, and compliance support, combined with ease of use and overall value for diverse lab environments.

Comparison Table

Sample tracking software is vital for modern labs to optimize workflows, maintain sample integrity, and enhance collaboration. This comparison table evaluates leading tools—such as Benchling, LabWare LIMS, STARLIMS, Thermo Fisher SampleManager, LabVantage, and others—outlining key features, scalability, and user needs to guide informed decisions.

1Benchling logo9.7/10

Cloud-based platform for tracking and managing biological samples, workflows, and data in biotech R&D.

Features
9.9/10
Ease
9.1/10
Value
8.7/10

Comprehensive LIMS for full lifecycle sample tracking, management, and compliance across labs.

Features
9.6/10
Ease
7.8/10
Value
8.4/10
3STARLIMS logo9.0/10

Flexible LIMS solution for efficient sample tracking, workflow automation, and regulatory compliance.

Features
9.5/10
Ease
7.8/10
Value
8.2/10

Integrated LIMS with advanced sample management and seamless instrument connectivity.

Features
9.2/10
Ease
7.4/10
Value
8.1/10
5LabVantage logo8.6/10

End-to-end LIMS platform for robust sample tracking and laboratory informatics.

Features
9.4/10
Ease
7.7/10
Value
8.1/10
6CoreLIMS logo8.2/10

Modular LIMS for streamlined sample lifecycle management and data integrity.

Features
9.1/10
Ease
7.4/10
Value
7.8/10
7Sapio LIMS logo8.6/10

Unified lab platform with intelligent sample tracking and assay data management.

Features
9.3/10
Ease
7.7/10
Value
8.1/10
8CloudLIMS logo8.2/10

Cloud-based LIMS for cost-effective sample tracking and collaboration in labs.

Features
9.1/10
Ease
7.4/10
Value
7.8/10
9Labguru logo8.1/10

All-in-one ELN and LIMS for research sample inventory and experiment tracking.

Features
8.5/10
Ease
7.7/10
Value
7.4/10
10SciNote logo8.1/10

Electronic lab notebook with integrated sample management and tracking features.

Features
8.3/10
Ease
8.7/10
Value
7.8/10
1
Benchling logo

Benchling

specialized

Cloud-based platform for tracking and managing biological samples, workflows, and data in biotech R&D.

Overall Rating9.7/10
Features
9.9/10
Ease of Use
9.1/10
Value
8.7/10
Standout Feature

Advanced sample lineage visualization that maps full history, parent-child relationships, and transformations across the R&D lifecycle

Benchling is a comprehensive cloud-based R&D platform tailored for life sciences, with robust sample tracking features that manage inventories, requests, fulfillment, and storage across lab workflows. It offers end-to-end traceability, including sample lineage, relationships, and audit trails to ensure compliance and data integrity. Ideal for biotech and pharma, it integrates seamlessly with ELNs, instruments, and other tools for streamlined operations.

Pros

  • Exceptional sample lineage and relationship mapping for full traceability
  • Seamless integrations with lab instruments, ELNs, and automation tools
  • Real-time collaboration, notifications, and customizable workflows

Cons

  • High enterprise-level pricing not ideal for small labs
  • Steep learning curve for advanced customizations
  • Limited offline access due to cloud dependency

Best For

Large biotech, pharmaceutical, and academic research teams needing scalable, compliant sample tracking at enterprise scale.

Pricing

Custom enterprise pricing, typically starting at $10,000+ annually per team or lab, with volume-based tiers.

Visit Benchlingbenchling.com
2
LabWare LIMS logo

LabWare LIMS

enterprise

Comprehensive LIMS for full lifecycle sample tracking, management, and compliance across labs.

Overall Rating9.2/10
Features
9.6/10
Ease of Use
7.8/10
Value
8.4/10
Standout Feature

Patented configuration tools allowing extensive no-code customization of workflows and interfaces

LabWare LIMS is a comprehensive laboratory information management system (LIMS) that excels in sample tracking, managing the entire sample lifecycle from receipt and logging to analysis, storage, and disposal. It offers robust workflow automation, instrument integration, and real-time tracking with full chain-of-custody documentation to ensure compliance in regulated environments. The platform supports customizable modules for various industries, including pharmaceuticals, biotech, food safety, and environmental testing, with advanced reporting and audit trail capabilities.

Pros

  • Highly configurable without programming via intuitive tools
  • Superior sample tracking with barcode/RFID support and chain-of-custody
  • Seamless integration with lab instruments and ERP systems

Cons

  • Steep learning curve and complex initial implementation
  • High cost unsuitable for small labs
  • Customization requires expertise for optimal setup

Best For

Large-scale laboratories in regulated industries like pharma and biotech needing enterprise-grade, customizable sample tracking and compliance management.

Pricing

Custom quote-based; perpetual licenses or SaaS subscriptions typically start at $50,000+ annually, scaling with users, modules, and deployment.

3
STARLIMS logo

STARLIMS

enterprise

Flexible LIMS solution for efficient sample tracking, workflow automation, and regulatory compliance.

Overall Rating9.0/10
Features
9.5/10
Ease of Use
7.8/10
Value
8.2/10
Standout Feature

User-configurable system with no-code/low-code workflow builder for tailored sample tracking processes

STARLIMS is a comprehensive Laboratory Information Management System (LIMS) from Abbott Informatics, specializing in end-to-end sample tracking, management, and workflow automation for laboratories. It handles sample accessioning, processing, storage, and disposal while ensuring full chain-of-custody traceability and compliance with regulations like 21 CFR Part 11, ISO 17025, and GxP. The platform supports diverse industries including pharmaceuticals, biotech, clinical, and environmental testing with scalable, configurable modules.

Pros

  • Highly configurable workflows with drag-and-drop interface
  • Robust regulatory compliance and audit trail features
  • Extensive instrument and ERP integrations

Cons

  • Steep learning curve and complex initial implementation
  • High cost unsuitable for small labs
  • Customization requires expertise

Best For

Large enterprise laboratories in regulated industries like pharma and biotech needing scalable, compliant sample tracking.

Pricing

Enterprise custom pricing; typically starts at $50,000+ annually based on users, modules, and deployment (on-premise or cloud).

Visit STARLIMSstarlims.com
4
Thermo Fisher SampleManager logo

Thermo Fisher SampleManager

enterprise

Integrated LIMS with advanced sample management and seamless instrument connectivity.

Overall Rating8.7/10
Features
9.2/10
Ease of Use
7.4/10
Value
8.1/10
Standout Feature

Visual Workflow Designer for customizable, no-code automation of complex sample processing pipelines

Thermo Fisher SampleManager is a comprehensive Laboratory Information Management System (LIMS) tailored for sample tracking and lab workflow automation in regulated industries like pharmaceuticals and biotech. It enables end-to-end sample lifecycle management, from accessioning and storage to testing, reporting, and disposal, with robust barcode/RFID tracking and audit trails. The platform integrates seamlessly with lab instruments and ensures compliance with standards such as 21 CFR Part 11, GLP, and GMP.

Pros

  • Exceptional sample traceability with real-time tracking and chain-of-custody features
  • Deep integration with Thermo Fisher instruments and third-party systems
  • Strong regulatory compliance tools including electronic signatures and audit trails

Cons

  • Complex setup and steep learning curve requiring extensive training
  • High implementation costs and dependency on professional services
  • Customization can be time-intensive and IT-heavy

Best For

Enterprise-level labs in highly regulated sectors like pharma and biotech that require scalable, compliant sample management.

Pricing

Custom enterprise pricing; typically $50,000+ annually for mid-sized deployments, plus implementation fees.

5
LabVantage logo

LabVantage

enterprise

End-to-end LIMS platform for robust sample tracking and laboratory informatics.

Overall Rating8.6/10
Features
9.4/10
Ease of Use
7.7/10
Value
8.1/10
Standout Feature

Integrated LIMS-ELN-LES platform with no-code configuration for seamless sample-to-result workflows

LabVantage is a comprehensive Laboratory Information Management System (LIMS) that excels in sample tracking, management, and lifecycle oversight for labs in pharmaceuticals, biotech, and research. It offers end-to-end visibility from sample intake to disposal, with automated workflows, instrument integration, and full audit trails for compliance. The platform supports high-throughput environments with scalable data management and analytics capabilities.

Pros

  • Robust sample lineage and chain-of-custody tracking with real-time visibility
  • Highly configurable low-code platform for custom workflows
  • Strong regulatory compliance (21 CFR Part 11, GxP) and instrument integrations

Cons

  • Complex initial setup and steep learning curve for non-experts
  • Enterprise pricing may be prohibitive for small labs
  • User interface feels dated compared to modern SaaS tools

Best For

Enterprise-level labs in regulated industries like pharma and biotech needing scalable, compliant sample tracking.

Pricing

Custom enterprise licensing starting at $50,000+ annually, based on users, modules, and deployment scale; contact sales for quotes.

Visit LabVantagelabvantage.com
6
CoreLIMS logo

CoreLIMS

enterprise

Modular LIMS for streamlined sample lifecycle management and data integrity.

Overall Rating8.2/10
Features
9.1/10
Ease of Use
7.4/10
Value
7.8/10
Standout Feature

No-code configuration engine for building tailored sample workflows without IT dependency

CoreLIMS is a robust, cloud-based Laboratory Information Management System (LIMS) from Waters Corporation, specializing in end-to-end sample tracking and management for scientific labs. It enables precise logging, real-time monitoring, and automated workflows for samples across their lifecycle, including barcode/RFID tracking, chain-of-custody audit trails, and integration with lab instruments. The platform supports customizable dashboards and reporting to ensure compliance and efficiency in regulated environments like biotech, pharma, and clinical research.

Pros

  • Comprehensive sample lifecycle tracking with audit trails and real-time status updates
  • Highly configurable no-code workflows and instrument integrations
  • Scalable for multi-site labs with strong compliance features (21 CFR Part 11)

Cons

  • Steep learning curve for initial setup and customization
  • Enterprise pricing may be prohibitive for small labs
  • Limited out-of-the-box templates for non-standard workflows

Best For

Mid-to-large research, biotech, or pharmaceutical labs needing scalable, compliant sample tracking with deep customization.

Pricing

Quote-based enterprise pricing; typically starts at $50,000+ annually depending on users, modules, and deployment scale.

Visit CoreLIMScorelims.com
7
Sapio LIMS logo

Sapio LIMS

specialized

Unified lab platform with intelligent sample tracking and assay data management.

Overall Rating8.6/10
Features
9.3/10
Ease of Use
7.7/10
Value
8.1/10
Standout Feature

Codeless Platform for drag-and-drop customization of sample workflows without programming expertise

Sapio LIMS is a flexible, enterprise-grade Laboratory Information Management System (LIMS) that excels in sample tracking, management, and lifecycle oversight for life sciences, biotech, and pharma labs. It provides comprehensive tools for sample registration, storage, aliquoting, pedigree tracking, and disposal, ensuring full chain-of-custody and compliance with regulations like 21 CFR Part 11. The platform unifies LIMS with ELN capabilities, enabling no-code/low-code workflow customization and seamless integrations with instruments and other systems.

Pros

  • Exceptional sample pedigree and lineage tracking with relationship mapping
  • No-code/low-code configuration for highly customizable workflows
  • Robust integrations with lab instruments, ELNs, and enterprise systems

Cons

  • Steep learning curve for complex configurations
  • Enterprise-level pricing requires custom quotes
  • Initial implementation can be time-intensive for large deployments

Best For

Mid-to-large biotech, pharmaceutical, and research labs requiring scalable, highly customizable sample tracking with regulatory compliance.

Pricing

Custom enterprise pricing via quote; typically starts at $50,000+ annually depending on users, modules, and deployment scale.

8
CloudLIMS logo

CloudLIMS

specialized

Cloud-based LIMS for cost-effective sample tracking and collaboration in labs.

Overall Rating8.2/10
Features
9.1/10
Ease of Use
7.4/10
Value
7.8/10
Standout Feature

Comprehensive sample genealogy and chain-of-custody tracking that provides full traceability from origin to disposal

CloudLIMS is a cloud-based Laboratory Information Management System (LIMS) specializing in comprehensive sample tracking and management for labs in biotech, clinical, pharmaceutical, and research sectors. It enables end-to-end sample lifecycle management, from accessioning and processing to storage, aliquoting, and disposal, with robust barcode/RFID tracking and chain-of-custody features. The platform supports customizable workflows, instrument integrations, inventory management, and ensures compliance with regulations like FDA 21 CFR Part 11, ISO 17025, and GLP.

Pros

  • Advanced sample tracking with genealogy, lot management, and real-time location monitoring via barcode and RFID
  • Strong regulatory compliance tools including audit trails, electronic signatures, and validation support
  • Scalable cloud architecture with multi-site capabilities, mobile access, and seamless instrument integrations

Cons

  • Steep learning curve due to extensive customization options and complex interface
  • Pricing is quote-based and can be expensive for smaller labs, with additional costs for customizations
  • Limited free trial and implementation may require professional services

Best For

Medium to large laboratories in regulated industries like pharma, biotech, and clinical testing that need robust, compliant sample tracking across multiple sites.

Pricing

Subscription-based with tiered plans starting around $500/month for basic setups; enterprise pricing is custom-quoted based on users, samples, and features.

Visit CloudLIMScloudlims.com
9
Labguru logo

Labguru

specialized

All-in-one ELN and LIMS for research sample inventory and experiment tracking.

Overall Rating8.1/10
Features
8.5/10
Ease of Use
7.7/10
Value
7.4/10
Standout Feature

Direct linkage between digital experiments in the ELN and physical sample locations/inventory for end-to-end traceability

Labguru is a cloud-based Electronic Lab Notebook (ELN) and LIMS platform designed to manage lab workflows, including comprehensive sample tracking from registration to disposal. It enables barcode/RFID scanning for real-time location tracking, aliquot management, and linkage to experiments and protocols. The software supports inventory control, compliance features like audit trails, and team collaboration across multi-site labs.

Pros

  • Robust sample tracking with barcode/RFID and real-time inventory visibility
  • Seamless integration of ELN, protocols, and sample management
  • Strong compliance tools including audit trails and GLP support

Cons

  • Steeper learning curve due to extensive feature set
  • Pricing is quote-based and can be expensive for smaller labs
  • Fewer native integrations with lab instruments compared to dedicated LIMS

Best For

Mid-sized biotech or academic labs seeking an all-in-one ELN and sample tracking solution with collaborative features.

Pricing

Custom quote-based pricing; basic plans start around $100/user/month, with enterprise tiers scaling up based on users and modules.

Visit Labgurulabguru.com
10
SciNote logo

SciNote

specialized

Electronic lab notebook with integrated sample management and tracking features.

Overall Rating8.1/10
Features
8.3/10
Ease of Use
8.7/10
Value
7.8/10
Standout Feature

Direct linking of inventory items to ELN protocols for automatic sample usage deduction and real-time stock updates

SciNote is a cloud-based Electronic Lab Notebook (ELN) with integrated inventory management tailored for sample tracking in research labs. It enables precise tracking of samples, reagents, and equipment through features like barcode/QR code scanning, location mapping, expiry date alerts, and usage history logging. The platform ensures full traceability by linking inventory directly to experimental protocols, supporting compliance standards such as 21 CFR Part 11 and GDPR.

Pros

  • Intuitive interface with mobile app support for on-the-go tracking
  • Strong regulatory compliance and audit trails for sample lineage
  • Seamless ELN-inventory integration reducing manual data entry

Cons

  • Limited advanced analytics and custom reporting compared to dedicated LIMS
  • Higher tiers required for full inventory features, increasing costs
  • Integration options with third-party lab instruments are basic

Best For

Small to mid-sized biotech and academic labs seeking an affordable, all-in-one ELN with reliable sample tracking.

Pricing

Free for academic single users; commercial plans start at €120/user/year (Notebook), up to €390/user/year (Advanced with full inventory); custom enterprise pricing.

Visit SciNotescinote.net

Conclusion

As the review demonstrated, the landscape of sample tracking software offers tools tailored to diverse needs, with Benchling leading as the top choice—its cloud-based platform excels in managing biological samples, workflows, and data, making it ideal for biotech R&D. Close behind, LabWare LIMS shines with its comprehensive lifecycle management and compliance focus, while STARLIMS impresses with its flexibility, automation capabilities, and regulatory alignment, ensuring strong alternatives for different lab priorities.

Benchling logo
Our Top Pick
Benchling

Ready to elevate your sample management? Start with Benchling to experience seamless tracking, integrated data handling, and streamlined workflows—your R&D efforts deserve the best tools, and Benchling delivers.