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Healthcare Medicine

Top 10 Best Primary Care Software of 2026

Explore top 10 primary care software solutions to streamline clinic operations. Find your perfect tool – start optimizing now!

Sarah Mitchell

Sarah Mitchell

Feb 11, 2026

10 tools comparedExpert reviewed
Independent evaluation · Unbiased commentary · Updated regularly
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Primary care software is vital for enhancing care delivery, simplifying administrative tasks, and fostering strong patient relationships. The tools featured here—spanning cloud-based EHRs, physician-centric platforms, free solutions, and enterprise-grade systems—cater to diverse primary care practices, ensuring there’s an option tailored to your workflow, size, and operational needs.

Quick Overview

  1. 1#1: athenaOne - Cloud-based EHR and practice management platform designed for primary care with integrated revenue cycle management and patient engagement tools.
  2. 2#2: Elation Health - Physician-centric EHR tailored for independent primary care practices, emphasizing clinical workflow efficiency and patient relationships.
  3. 3#3: eClinicalWorks - Comprehensive EHR solution for primary care offering telehealth, population health management, and interoperability features.
  4. 4#4: NextGen Healthcare - Ambulatory EHR and practice management system optimized for primary care with strong analytics and billing capabilities.
  5. 5#5: Practice Fusion - Free cloud-based EHR for primary care practices with charting, e-prescribing, and scheduling functionalities.
  6. 6#6: Kareo - Billing and practice management software with integrated EHR for small to mid-sized primary care providers.
  7. 7#7: AdvancedMD - All-in-one practice management and EHR platform supporting primary care with patient portal and appointment scheduling.
  8. 8#8: CharmHealth - Affordable EHR and telemedicine solution for primary care featuring customizable templates and patient messaging.
  9. 9#9: DrChrono - iPad-native EHR for primary care with voice dictation, billing, and mobile accessibility.
  10. 10#10: Epic - Enterprise-grade EHR widely used in primary care settings with advanced interoperability and customization options.

Tools were selected and ranked based on clinical functionality, workflow efficiency, patient engagement features, interoperability, and overall value, ensuring they meet the unique demands of modern primary care settings.

Comparison Table

Navigating primary care software requires careful consideration, and this comparison table breaks down top tools like athenaOne, Elation Health, eClinicalWorks, NextGen Healthcare, Practice Fusion, and more. Readers will gain insights into each platform’s key features, usability, and functionality, enabling them to select a solution that best fits their practice’s specific needs for efficient, patient-focused care.

1athenaOne logo9.4/10

Cloud-based EHR and practice management platform designed for primary care with integrated revenue cycle management and patient engagement tools.

Features
9.6/10
Ease
9.2/10
Value
9.0/10

Physician-centric EHR tailored for independent primary care practices, emphasizing clinical workflow efficiency and patient relationships.

Features
9.1/10
Ease
9.6/10
Value
8.7/10

Comprehensive EHR solution for primary care offering telehealth, population health management, and interoperability features.

Features
8.7/10
Ease
7.2/10
Value
7.8/10

Ambulatory EHR and practice management system optimized for primary care with strong analytics and billing capabilities.

Features
8.8/10
Ease
7.6/10
Value
8.0/10

Free cloud-based EHR for primary care practices with charting, e-prescribing, and scheduling functionalities.

Features
7.5/10
Ease
8.5/10
Value
9.2/10
6Kareo logo8.3/10

Billing and practice management software with integrated EHR for small to mid-sized primary care providers.

Features
8.2/10
Ease
8.7/10
Value
8.1/10
7AdvancedMD logo8.2/10

All-in-one practice management and EHR platform supporting primary care with patient portal and appointment scheduling.

Features
8.7/10
Ease
7.8/10
Value
7.5/10

Affordable EHR and telemedicine solution for primary care featuring customizable templates and patient messaging.

Features
8.0/10
Ease
8.5/10
Value
8.7/10
9DrChrono logo8.1/10

iPad-native EHR for primary care with voice dictation, billing, and mobile accessibility.

Features
8.4/10
Ease
7.9/10
Value
7.6/10
10Epic logo8.5/10

Enterprise-grade EHR widely used in primary care settings with advanced interoperability and customization options.

Features
9.8/10
Ease
6.2/10
Value
7.1/10
1
athenaOne logo

athenaOne

enterprise

Cloud-based EHR and practice management platform designed for primary care with integrated revenue cycle management and patient engagement tools.

Overall Rating9.4/10
Features
9.6/10
Ease of Use
9.2/10
Value
9.0/10
Standout Feature

AI-powered Revenue Cycle Intelligence for automated claim optimization and predictive denial management

athenaOne by athenahealth is a comprehensive cloud-based EHR and practice management platform tailored for primary care and ambulatory practices. It seamlessly integrates clinical documentation, appointment scheduling, billing, patient engagement, and population health management into a single, intuitive system. Leveraging AI-powered tools, it optimizes workflows, enhances revenue cycle performance, and supports interoperability with external systems for efficient care delivery.

Pros

  • Exceptional revenue cycle management with AI-driven coding and denial prevention for higher collections
  • Seamless interoperability and patient portal for improved care coordination and engagement
  • Cloud-based scalability with robust analytics for population health and quality reporting

Cons

  • Higher upfront implementation costs and time for larger practices
  • Pricing model can feel premium compared to basic EHR alternatives
  • Customization options may require additional vendor support

Best For

Mid-sized to large primary care practices prioritizing integrated EHR, billing optimization, and AI insights for revenue and outcomes.

Pricing

Custom subscription pricing starting at ~$400-$700 per provider/month, including EHR, PM, patient engagement, and support; scales with practice size.

Visit athenaOneathenahealth.com
2
Elation Health logo

Elation Health

specialized

Physician-centric EHR tailored for independent primary care practices, emphasizing clinical workflow efficiency and patient relationships.

Overall Rating9.3/10
Features
9.1/10
Ease of Use
9.6/10
Value
8.7/10
Standout Feature

Physician-optimized charting with one-click actions and automated clinical summaries for faster, more accurate documentation

Elation Health is a cloud-based EHR and practice management platform tailored specifically for primary care physicians and independent practices. It emphasizes clinician-friendly design with intuitive workflows that prioritize patient relationships over administrative tasks, including seamless charting, automated reminders, and integrated billing. The system supports telehealth, patient portals, and population health tools to deliver comprehensive primary care.

Pros

  • Highly intuitive interface with keyboard-driven navigation designed by physicians
  • Primary care-specific workflows that reduce documentation time
  • Strong patient engagement via secure messaging and portal

Cons

  • Premium pricing may strain very small or solo practices
  • Limited customization options compared to larger enterprise EHRs
  • Some third-party integrations require additional configuration

Best For

Independent primary care physicians and small practices seeking a clinician-first EHR that minimizes administrative overhead.

Pricing

Starts at $299 per provider per month (billed annually), all-inclusive with EHR, practice management, telehealth, and support.

Visit Elation Healthelationhealth.com
3
eClinicalWorks logo

eClinicalWorks

enterprise

Comprehensive EHR solution for primary care offering telehealth, population health management, and interoperability features.

Overall Rating8.0/10
Features
8.7/10
Ease of Use
7.2/10
Value
7.8/10
Standout Feature

Sunoh.ai ambient AI scribing for hands-free automated clinical documentation

eClinicalWorks is a comprehensive EHR and practice management platform designed for primary care providers, offering electronic health records, scheduling, billing, and telehealth integration. It includes patient engagement tools like the Healow portal and AI-driven features for documentation and analytics. Widely used in ambulatory settings, it supports scalable workflows from small practices to large networks.

Pros

  • Integrated telehealth and patient portal (Healow)
  • AI tools like Sunoh.ai for ambient scribing
  • Strong population health and reporting capabilities

Cons

  • Steep learning curve and dated interface
  • Inconsistent customer support response times
  • High upfront implementation and customization costs

Best For

Small to mid-sized primary care practices and community health centers needing an all-in-one scalable EHR with telehealth.

Pricing

Subscription-based; starts at ~$449 per provider/month for core EHR/PM, with custom quotes for full suite including telehealth.

Visit eClinicalWorkseclinicalworks.com
4
NextGen Healthcare logo

NextGen Healthcare

enterprise

Ambulatory EHR and practice management system optimized for primary care with strong analytics and billing capabilities.

Overall Rating8.4/10
Features
8.8/10
Ease of Use
7.6/10
Value
8.0/10
Standout Feature

Advanced Population Health platform with predictive analytics and risk stratification

NextGen Healthcare provides a robust electronic health record (EHR) and practice management platform designed for ambulatory care, including primary care practices. It offers comprehensive tools for clinical documentation, e-prescribing, scheduling, billing, and patient engagement through a secure portal. The solution emphasizes interoperability, population health analytics, and revenue cycle management to support value-based care models.

Pros

  • Extensive feature set including advanced clinical decision support and population health tools
  • Strong interoperability with labs, hospitals, and other systems via FHIR standards
  • Integrated revenue cycle management that streamlines billing and claims processing

Cons

  • Steep learning curve due to complex interface and customization needs
  • High implementation costs and longer onboarding times
  • Customer support response can be inconsistent for smaller practices

Best For

Mid-to-large primary care practices requiring enterprise-level EHR with strong analytics and revenue optimization.

Pricing

Quote-based subscription; typically $400-$700 per provider/month, plus implementation fees starting at $50K+.

5
Practice Fusion logo

Practice Fusion

specialized

Free cloud-based EHR for primary care practices with charting, e-prescribing, and scheduling functionalities.

Overall Rating7.8/10
Features
7.5/10
Ease of Use
8.5/10
Value
9.2/10
Standout Feature

Ad-supported free EHR model that eliminates subscription barriers for small practices

Practice Fusion is a cloud-based electronic health record (EHR) system tailored for primary care practices, offering tools for charting, e-prescribing, appointment scheduling, and patient communication. It supports clinical workflows with customizable templates, lab integrations, and immunization tracking to streamline daily operations. As one of the first web-based EHRs, it emphasizes accessibility and has helped thousands of providers achieve meaningful use certification.

Pros

  • Free core EHR functionality with no upfront costs
  • Intuitive, browser-based interface requiring minimal training
  • Robust e-prescribing and lab integration for primary care workflows

Cons

  • Intrusive ads on the dashboard that can distract users
  • Limited advanced reporting and customization options
  • Customer support primarily ticket-based with variable response times

Best For

Small primary care practices or solo providers seeking a cost-effective, easy-to-implement EHR without complex setup.

Pricing

Free for basic features (ad-supported); optional paid add-ons for advanced tools and ad removal starting at $149/month per provider.

Visit Practice Fusionpracticefusion.com
6
Kareo logo

Kareo

enterprise

Billing and practice management software with integrated EHR for small to mid-sized primary care providers.

Overall Rating8.3/10
Features
8.2/10
Ease of Use
8.7/10
Value
8.1/10
Standout Feature

Kareo Intelligence for proactive claims denial prevention and revenue optimization

Kareo is a cloud-based EHR and practice management platform designed for independent medical practices, including primary care, offering integrated tools for patient scheduling, charting, e-prescribing, and billing. It streamlines revenue cycle management with automated claims processing and patient eligibility verification. The system emphasizes ease of use and scalability for small to mid-sized practices handling everyday primary care workflows.

Pros

  • Superior revenue cycle management with automated claims scrubbing and fast reimbursements
  • Intuitive interface with minimal training required
  • Strong mobile access and patient portal features

Cons

  • Limited advanced customization for complex workflows
  • Reporting tools lack depth compared to enterprise solutions
  • Customer support can be inconsistent during peak times

Best For

Small to mid-sized primary care practices needing a straightforward, affordable EHR with strong billing capabilities.

Pricing

Starts at about $160 per provider per month for core EHR and PM, with add-ons for billing services and advanced features; custom quotes common.

Visit Kareokareo.com
7
AdvancedMD logo

AdvancedMD

enterprise

All-in-one practice management and EHR platform supporting primary care with patient portal and appointment scheduling.

Overall Rating8.2/10
Features
8.7/10
Ease of Use
7.8/10
Value
7.5/10
Standout Feature

Integrated Revenue Cycle Management with AI-driven denial management

AdvancedMD is a cloud-based electronic health record (EHR) and practice management platform designed for medical practices, including primary care providers. It streamlines workflows with features like appointment scheduling, billing, patient portals, telehealth, and customizable charting. The software emphasizes revenue cycle management and interoperability to enhance efficiency and compliance in primary care settings.

Pros

  • Robust revenue cycle management with denial prevention tools
  • Strong interoperability and integration with labs/pharmacies
  • Comprehensive patient engagement via portal and telehealth

Cons

  • High cost with complex pricing structure
  • Steep learning curve for customization
  • Customer support response times can vary

Best For

Mid-sized primary care practices prioritizing billing efficiency and regulatory compliance.

Pricing

Custom subscription starting at ~$400/provider/month; full suite ~$729+/month with add-ons for advanced features.

Visit AdvancedMDadvancedmd.com
8
CharmHealth logo

CharmHealth

specialized

Affordable EHR and telemedicine solution for primary care featuring customizable templates and patient messaging.

Overall Rating8.1/10
Features
8.0/10
Ease of Use
8.5/10
Value
8.7/10
Standout Feature

All-in-one integration of EHR, practice management, and patient portal with built-in MIPS reporting for easy compliance.

CharmHealth is a cloud-based EHR and practice management platform designed for primary care providers, offering tools for patient charting, scheduling, billing, e-prescribing, and telehealth. It supports solo practitioners and small to mid-sized practices with customizable templates and mobile access. The software emphasizes compliance with HIPAA and meaningful use requirements while integrating labs and pharmacies seamlessly.

Pros

  • Affordable pricing with a free tier for solo providers
  • Intuitive interface and mobile app for on-the-go access
  • Strong patient engagement tools including portal and telehealth

Cons

  • Limited advanced customization compared to enterprise solutions
  • Customer support response times can vary
  • Some users report occasional performance lags during peak hours

Best For

Small to mid-sized primary care practices looking for a cost-effective, user-friendly all-in-one EHR system.

Pricing

Free for basic solo use; paid plans start at $259/provider/month (billed annually) for Premium features including telehealth and advanced billing.

Visit CharmHealthcharmhealth.com
9
DrChrono logo

DrChrono

specialized

iPad-native EHR for primary care with voice dictation, billing, and mobile accessibility.

Overall Rating8.1/10
Features
8.4/10
Ease of Use
7.9/10
Value
7.6/10
Standout Feature

Native iPad app for handwriting recognition and real-time charting without a computer

DrChrono is a cloud-based electronic health record (EHR) and practice management software tailored for primary care practices, offering tools for scheduling, charting, billing, e-prescribing, and telehealth. It supports customizable templates, patient portals, and revenue cycle management to streamline workflows. The platform is particularly noted for its mobile-first design, enabling efficient use on iPads and iPhones during patient encounters.

Pros

  • Robust mobile app optimized for iOS devices, ideal for on-the-go charting
  • Integrated billing and MIPS reporting for efficient revenue management
  • Customizable EHR templates and strong e-prescribing capabilities

Cons

  • Steep learning curve for new users and complex customizations
  • Pricing requires custom quotes and can be expensive for small practices
  • Customer support response times can be inconsistent

Best For

Small to mid-sized primary care practices seeking mobile-friendly EHR with strong billing integration.

Pricing

Starts at $199 per provider/month for core EHR, with add-ons for telehealth ($40+/month) and billing; custom enterprise pricing available.

Visit DrChronodrchrono.com
10
Epic logo

Epic

enterprise

Enterprise-grade EHR widely used in primary care settings with advanced interoperability and customization options.

Overall Rating8.5/10
Features
9.8/10
Ease of Use
6.2/10
Value
7.1/10
Standout Feature

Care Everywhere network for real-time, nationwide health information exchange across millions of patients.

Epic is a comprehensive electronic health record (EHR) system widely used in large healthcare organizations, providing robust tools for primary care such as patient charting, appointment scheduling, e-prescribing, billing, and population health management. It excels in interoperability through its Care Everywhere network, enabling seamless data sharing across unaffiliated providers. Designed for enterprise-scale deployment, Epic supports advanced analytics and customization but requires significant resources for implementation.

Pros

  • Unmatched feature depth and scalability for complex primary care workflows
  • Superior interoperability via Care Everywhere for cross-provider data exchange
  • Strong analytics and reporting for population health management

Cons

  • Steep learning curve requiring extensive training and customization
  • Prohibitively high implementation and ongoing costs
  • Overkill for small or independent primary care practices

Best For

Large primary care networks or health systems integrated with hospitals needing enterprise-level EHR capabilities.

Pricing

Custom enterprise pricing with multi-million-dollar implementation fees and annual subscriptions scaling by user volume and modules.

Visit Epicepic.com

Conclusion

The reviewed primary care software provides varied solutions, with athenaOne emerging as the top choice for its comprehensive cloud-based EHR, integrated revenue cycle management, and patient engagement tools. Elation Health shines with its physician-centric design and optimized clinical workflows, while eClinicalWorks impresses with advanced telehealth and interoperability features. Regardless of practice size or specific needs, these platforms demonstrate strong capabilities to elevate care.

athenaOne logo
Our Top Pick
athenaOne

Take the next step in enhancing your practice—try athenaOne to unlock its integrated tools and seamless patient care management.