Top 10 Best Physician Practice Management Software of 2026

athenaOne by athenahealth is a comprehensive cloud-based electronic health record (EHR) and practice management software suite tailored for physician practices. It integrates scheduling, billing, claims management, patient engagement, and clinical workflows into a single platform to streamline operations and boost revenue cycle performance. With strong emphasis on interoperability and data analytics, it enables practices to achieve higher efficiency and better financial outcomes while maintaining compliance with healthcare regulations.

AdvancedMD is a cloud-based, all-in-one platform offering electronic health records (EHR), practice management, billing, and patient engagement tools designed specifically for physician practices. It streamlines appointment scheduling, claims processing, eligibility verification, and compliance with HIPAA and MIPS requirements. The software provides customizable dashboards, robust analytics, and interoperability with labs and pharmacies to enhance operational efficiency and revenue cycle management.

Kareo is a cloud-based practice management software designed for independent medical practices, offering integrated tools for scheduling, billing, revenue cycle management, and electronic health records (EHR). It streamlines administrative workflows, automates claims processing, and provides patient engagement features like online booking and telehealth. Kareo emphasizes financial optimization with high clean claim rates and compliance support, making it suitable for small to mid-sized physician groups.

eClinicalWorks is a cloud-based electronic health record (EHR) and practice management software suite tailored for physician practices, offering integrated tools for scheduling, billing, claims management, and revenue cycle optimization. It supports comprehensive patient engagement through its Healow patient portal and telehealth features, enabling virtual visits and secure communication. The platform also provides robust reporting, analytics, and interoperability with labs and other systems to streamline practice workflows.

NextGen Office is a robust practice management software solution from NextGen Healthcare, designed specifically for physician practices to streamline administrative workflows including appointment scheduling, billing, claims processing, and financial reporting. It integrates tightly with NextGen's EHR platform, enabling a unified system for clinical and operational management. The software emphasizes revenue cycle management with advanced analytics and interoperability features to support mid-sized to large practices.

Allscripts Professional is a comprehensive EHR and practice management software suite tailored for physician practices, offering integrated tools for scheduling, billing, claims management, and patient eligibility verification. It streamlines revenue cycle management with features like automated coding, denial management, and reporting for compliance with regulations such as HIPAA and MIPS. Designed primarily for ambulatory settings, it supports scalability across small to large practices while integrating with other Allscripts modules for enhanced interoperability.

DrChrono is a cloud-based electronic health record (EHR) and practice management software tailored for physician practices, offering integrated tools for scheduling, billing, patient engagement, and telehealth. It supports customizable workflows, e-prescribing, lab integrations, and revenue cycle management to streamline administrative tasks. The platform stands out for its mobile-first design, with native apps for iOS and Android devices, enabling on-the-go access for providers.

Practice Fusion is a cloud-based electronic health record (EHR) and practice management software designed for physicians, offering tools for patient charting, scheduling, e-prescribing, and billing integration. It streamlines clinical workflows and administrative tasks in a web-accessible platform without upfront costs. As a certified EHR, it supports meaningful use requirements and includes a patient portal for engagement.

Prime Suite by Greenway Health is a comprehensive EHR and practice management software designed for ambulatory physician practices, integrating patient scheduling, billing, claims management, and electronic health records into a single platform. It supports revenue cycle management with automated workflows for eligibility verification, coding, and collections. The solution is ONC-certified and emphasizes interoperability with labs, pharmacies, and other systems to streamline operations.

Amazing Charts is a certified EHR and practice management software tailored for physicians, offering integrated tools for charting, scheduling, billing, and patient management. It emphasizes physician productivity with a point-and-click interface and customizable templates that enable 'charting by exception' to document only deviations from normal. Ideal for small to mid-sized practices, it streamlines workflows while supporting meaningful use requirements and regulatory compliance.