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Healthcare Medicine

Top 10 Best Physician Billing Software of 2026

Compare top physician billing software to streamline claims. Find the best fit for your practice today.

Gitnux Team

Feb 11, 2026

10 tools comparedExpert reviewed
Independent evaluation · Unbiased commentary · Updated regularly
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Physician billing software is critical for streamlining revenue cycles, from claims processing to patient payments, and the right tool directly impacts practice efficiency and financial health. With options ranging from cloud-based EHR suites to mobile-first platforms, selecting the best solution requires aligning with specific needs—this review examines the top 10 tools to guide informed decisions.

Quick Overview

  1. 1#1: athenaOne - Cloud-based EHR and revenue cycle management platform that automates medical billing, claims processing, and patient payments for physicians.
  2. 2#2: Kareo - Comprehensive medical billing and practice management software designed for independent physician practices with integrated claims scrubbing and denial management.
  3. 3#3: AdvancedMD - All-in-one practice management, EHR, and billing solution that streamlines insurance claims, patient billing, and revenue cycle for medical practices.
  4. 4#4: DrChrono - Mobile-first EHR and medical billing platform that handles scheduling, claims submission, and ERA posting for efficient physician revenue management.
  5. 5#5: eClinicalWorks - Integrated EHR system with robust billing features including automated claims, eligibility verification, and payment posting for physician practices.
  6. 6#6: NextGen Office - Practice management and EHR software with advanced billing tools for claims management, AR follow-up, and financial reporting in physician offices.
  7. 7#7: CureMD - Cloud-based EHR and practice management suite that provides end-to-end medical billing, including superbills, claims tracking, and patient statements.
  8. 8#8: CollaborateMD - Cloud-based medical billing software focused on claims processing, denial management, and payment reconciliation for physician practices.
  9. 9#9: Practice Fusion - Web-based EHR with integrated billing services for electronic claims submission and patient payment collection in small physician practices.
  10. 10#10: Office Ally - Free online portal for medical billing, claims clearinghouse services, and ERA processing tailored for independent healthcare providers.

Tools were ranked based on features like automated claims and denial management, ease of use, system reliability, and value, ensuring relevance across practice sizes and clinical workflows.

Comparison Table

This comparison table examines leading physician billing software tools—including athenaOne, Kareo, AdvancedMD, DrChrono, eClinicalWorks, and more—designed to help healthcare practices streamline operations. Readers will discover key features, pricing nuances, and usability aspects to identify the best fit for their specific needs, from integration capabilities to patient billing management.

1athenaOne logo9.2/10

Cloud-based EHR and revenue cycle management platform that automates medical billing, claims processing, and patient payments for physicians.

Features
9.6/10
Ease
8.4/10
Value
8.7/10
2Kareo logo9.2/10

Comprehensive medical billing and practice management software designed for independent physician practices with integrated claims scrubbing and denial management.

Features
9.5/10
Ease
9.0/10
Value
8.8/10
3AdvancedMD logo8.6/10

All-in-one practice management, EHR, and billing solution that streamlines insurance claims, patient billing, and revenue cycle for medical practices.

Features
9.2/10
Ease
8.0/10
Value
7.8/10
4DrChrono logo8.4/10

Mobile-first EHR and medical billing platform that handles scheduling, claims submission, and ERA posting for efficient physician revenue management.

Features
8.7/10
Ease
8.2/10
Value
7.8/10

Integrated EHR system with robust billing features including automated claims, eligibility verification, and payment posting for physician practices.

Features
8.2/10
Ease
6.8/10
Value
7.1/10

Practice management and EHR software with advanced billing tools for claims management, AR follow-up, and financial reporting in physician offices.

Features
8.6/10
Ease
7.4/10
Value
7.8/10
7CureMD logo7.8/10

Cloud-based EHR and practice management suite that provides end-to-end medical billing, including superbills, claims tracking, and patient statements.

Features
8.5/10
Ease
7.0/10
Value
7.5/10

Cloud-based medical billing software focused on claims processing, denial management, and payment reconciliation for physician practices.

Features
8.6/10
Ease
8.8/10
Value
8.0/10

Web-based EHR with integrated billing services for electronic claims submission and patient payment collection in small physician practices.

Features
6.5/10
Ease
7.8/10
Value
8.5/10
10Office Ally logo7.8/10

Free online portal for medical billing, claims clearinghouse services, and ERA processing tailored for independent healthcare providers.

Features
7.5/10
Ease
8.5/10
Value
9.0/10
1
athenaOne logo

athenaOne

enterprise

Cloud-based EHR and revenue cycle management platform that automates medical billing, claims processing, and patient payments for physicians.

Overall Rating9.2/10
Features
9.6/10
Ease of Use
8.4/10
Value
8.7/10
Standout Feature

The athenahealth Network, providing unparalleled payer connectivity and real-time data exchange for faster reimbursements.

athenaOne by athenahealth is a comprehensive cloud-based platform that integrates electronic health records (EHR) with advanced revenue cycle management (RCM) for physician billing. It automates claims scrubbing, submission, eligibility verification, and denial management to maximize reimbursements and reduce administrative burdens. With real-time analytics and payer connectivity through the athenahealth Network, it helps practices optimize cash flow and financial performance across specialties.

Pros

  • Superior claims accuracy with 98%+ first-pass acceptance rates
  • Integrated EHR-billing workflow reduces errors and coding time
  • Advanced analytics and AI-driven denial prevention tools

Cons

  • High implementation costs and ongoing subscription fees
  • Interface can feel clunky for smaller practices
  • Customer support response times vary

Best For

Mid-to-large physician practices seeking an all-in-one EHR and billing solution with enterprise-level revenue cycle automation.

Pricing

Subscription-based starting at $450-$700 per provider per month, plus one-time implementation fees of $5,000-$50,000 depending on practice size.

Visit athenaOneathenahealth.com
2
Kareo logo

Kareo

specialized

Comprehensive medical billing and practice management software designed for independent physician practices with integrated claims scrubbing and denial management.

Overall Rating9.2/10
Features
9.5/10
Ease of Use
9.0/10
Value
8.8/10
Standout Feature

AI-powered claim scrubbing and denial prediction that achieves industry-leading first-pass acceptance rates.

Kareo is a cloud-based physician billing software designed to streamline revenue cycle management for independent medical practices. It automates claims submission, payment posting, denial management, and eligibility verification to maximize reimbursements and reduce administrative burdens. Integrated with EHR and practice management tools, Kareo provides real-time analytics and reporting for financial performance insights.

Pros

  • High clean claims rate (up to 99%) with automated scrubbing
  • Robust denial management and AR recovery tools
  • Seamless integration with popular EHRs and intuitive dashboard

Cons

  • Pricing scales quickly for multi-provider practices
  • Limited advanced customization for complex billing scenarios
  • Customer support response times can vary during peak periods

Best For

Small to mid-sized independent physician practices looking for an integrated, user-friendly billing solution to optimize revenue cycles.

Pricing

Starts at $110 per provider/month for core billing, plus per-claim fees (~$0.35/claim); full suite with EHR from $300+/provider/month.

Visit Kareokareo.com
3
AdvancedMD logo

AdvancedMD

enterprise

All-in-one practice management, EHR, and billing solution that streamlines insurance claims, patient billing, and revenue cycle for medical practices.

Overall Rating8.6/10
Features
9.2/10
Ease of Use
8.0/10
Value
7.8/10
Standout Feature

Advanced claims intelligence engine achieving up to 99% clean claims rate

AdvancedMD is a comprehensive cloud-based platform offering physician billing software as part of its integrated EHR and practice management suite. It excels in revenue cycle management with features like automated claims submission, scrubbing, denial management, and payment posting. The software supports eligibility verification, AR tracking, and analytics to optimize cash flow for medical practices.

Pros

  • Robust claims scrubbing and denial management tools
  • Seamless integration with EHR and scheduling
  • Scalable for multi-location practices with strong analytics

Cons

  • High pricing for full suite access
  • Steep learning curve for advanced features
  • Mixed customer support experiences

Best For

Medium to large physician practices needing integrated billing with EHR and advanced RCM capabilities.

Pricing

Custom quote-based pricing; typically starts at $400-$800 per provider/month including billing module.

Visit AdvancedMDadvancedmd.com
4
DrChrono logo

DrChrono

specialized

Mobile-first EHR and medical billing platform that handles scheduling, claims submission, and ERA posting for efficient physician revenue management.

Overall Rating8.4/10
Features
8.7/10
Ease of Use
8.2/10
Value
7.8/10
Standout Feature

Native iOS apps enabling full billing cycle management directly from iPad or iPhone devices

DrChrono is a cloud-based electronic health record (EHR) and practice management platform with integrated physician billing software designed to streamline revenue cycle management. It automates claims submission to Medicare, Medicaid, and commercial payers, handles electronic remittance advice (ERA) posting, and provides denial management tools. The platform supports accurate coding with ICD-10 and CPT integration, eligibility verification, and detailed financial reporting to optimize collections.

Pros

  • Seamless integration between EHR charting and billing workflows
  • Mobile-first design with iPad and iPhone apps for on-the-go billing
  • Robust claims scrubbing and real-time eligibility checks to reduce denials

Cons

  • Higher pricing that may strain small practices
  • Steeper learning curve for non-tech-savvy users during setup
  • Customer support response times can be inconsistent

Best For

Small to mid-sized physician practices seeking an all-in-one EHR platform with strong mobile billing capabilities.

Pricing

Subscription-based starting at $199 per provider/month for core EHR and billing, with custom quotes for advanced features and add-ons.

Visit DrChronodrchrono.com
5
eClinicalWorks logo

eClinicalWorks

enterprise

Integrated EHR system with robust billing features including automated claims, eligibility verification, and payment posting for physician practices.

Overall Rating7.6/10
Features
8.2/10
Ease of Use
6.8/10
Value
7.1/10
Standout Feature

AI-powered predictive denial management that proactively identifies and resolves billing issues

eClinicalWorks is a comprehensive EHR platform with integrated physician billing software that streamlines revenue cycle management for medical practices. It offers automated claims submission, eligibility verification, denial management, and AR tracking, all within a unified system. The billing module supports multiple specialties and provides detailed financial reporting to optimize cash flow.

Pros

  • Seamless integration with EHR for end-to-end workflows
  • Advanced denial management and claims scrubbing tools
  • Scalable analytics and reporting for large practices

Cons

  • Steep learning curve and outdated interface
  • Frequent complaints about customer support response times
  • High implementation costs and lengthy setup

Best For

Large multi-specialty practices or hospitals needing robust, integrated EHR and billing capabilities.

Pricing

Quote-based pricing, typically $449+ per provider/month including EHR and billing, plus one-time implementation fees.

Visit eClinicalWorkseclinicalworks.com
6
NextGen Office logo

NextGen Office

enterprise

Practice management and EHR software with advanced billing tools for claims management, AR follow-up, and financial reporting in physician offices.

Overall Rating8.1/10
Features
8.6/10
Ease of Use
7.4/10
Value
7.8/10
Standout Feature

Advanced Revenue Cycle Analytics Dashboard for real-time insights into claims performance and denial trends

NextGen Office is a comprehensive electronic health record (EHR) and practice management solution from NextGen Healthcare, with robust physician billing features including claims processing, eligibility verification, and revenue cycle management. It integrates seamlessly with clinical workflows to streamline billing, reduce denials, and accelerate reimbursements for medical practices. The platform offers advanced analytics and reporting tools to optimize financial performance and ensure compliance with healthcare regulations.

Pros

  • Integrated EHR and billing for efficient workflows
  • Powerful analytics and denial management tools
  • Strong compliance features and payer connectivity

Cons

  • Steep learning curve for new users
  • Custom pricing can be expensive for smaller practices
  • Interface feels dated compared to modern competitors

Best For

Mid-sized physician practices seeking an all-in-one EHR and billing solution with advanced revenue cycle analytics.

Pricing

Custom pricing based on practice size and modules; typically starts at $400+ per provider per month with implementation fees.

7
CureMD logo

CureMD

specialized

Cloud-based EHR and practice management suite that provides end-to-end medical billing, including superbills, claims tracking, and patient statements.

Overall Rating7.8/10
Features
8.5/10
Ease of Use
7.0/10
Value
7.5/10
Standout Feature

Intelligent claims scrubbing with real-time eligibility checks and automated denial prevention

CureMD is a cloud-based EHR and practice management platform with integrated physician billing capabilities, designed to streamline revenue cycle management for medical practices. It handles electronic claims submission, insurance eligibility verification, payment posting, and denial management to optimize reimbursements. The software integrates billing directly with patient records, reducing errors and supporting compliance with HIPAA and coding standards like ICD-10.

Pros

  • Seamless integration of EHR and billing for efficient workflows
  • Robust claims scrubbing and denial management tools
  • Comprehensive reporting and analytics for AR tracking

Cons

  • Steep learning curve for new users due to complex interface
  • Custom pricing can be expensive for small practices
  • Occasional reports of slow customer support response times

Best For

Medium-sized physician practices needing an all-in-one EHR with strong revenue cycle management and billing automation.

Pricing

Custom subscription pricing starting at around $395 per provider per month, plus one-time implementation fees and optional add-ons.

Visit CureMDcuremd.com
8
CollaborateMD logo

CollaborateMD

specialized

Cloud-based medical billing software focused on claims processing, denial management, and payment reconciliation for physician practices.

Overall Rating8.4/10
Features
8.6/10
Ease of Use
8.8/10
Value
8.0/10
Standout Feature

Intelligent denial management that auto-scrubs claims and provides resolution workflows to accelerate reimbursements.

CollaborateMD is a cloud-based medical billing and practice management software tailored for physician practices, focusing on streamlining the revenue cycle. It handles electronic claims submission, scrubbing, denial management, patient eligibility verification, payment posting, and comprehensive reporting. The platform integrates billing with basic practice management tools like scheduling and patient statements to improve cash flow and reduce administrative burdens.

Pros

  • Fast and reliable claims processing with built-in scrubbing to minimize denials
  • Exceptional customer support with dedicated billing specialists
  • Customizable reports and dashboards for detailed financial insights

Cons

  • Pricing scales quickly with additional providers or users
  • Limited native EHR capabilities, requiring third-party integrations
  • Occasional reports of slow performance during peak usage

Best For

Small to mid-sized physician practices prioritizing efficient billing and revenue cycle management over full EHR functionality.

Pricing

Starts at $389 per provider per month (billed annually), plus setup fees and optional clearinghouse services ($0.09-$0.25 per claim).

Visit CollaborateMDcollaboratemd.com
9
Practice Fusion logo

Practice Fusion

specialized

Web-based EHR with integrated billing services for electronic claims submission and patient payment collection in small physician practices.

Overall Rating7.1/10
Features
6.5/10
Ease of Use
7.8/10
Value
8.5/10
Standout Feature

Fully free, ad-supported EHR with built-in billing for zero upfront costs

Practice Fusion is a cloud-based electronic health record (EHR) system that includes integrated physician billing tools, enabling claim creation, electronic submission, eligibility verification, and basic revenue cycle management. Designed primarily for small to mid-sized practices, it generates superbills and supports ERA posting through partnerships with clearinghouses. While not a standalone billing powerhouse, its billing features are tightly woven into the free EHR workflow for streamlined operations.

Pros

  • Cost-effective with free core EHR and low per-claim fees
  • Seamless integration between charting and billing workflows
  • Supports electronic claims submission and basic tracking

Cons

  • Lacks advanced RCM tools like denial management or analytics
  • Relies on third-party clearinghouses with extra fees
  • Limited customization for complex multi-provider billing

Best For

Small independent practices seeking an affordable, all-in-one EHR with basic billing capabilities.

Pricing

Free EHR platform; electronic claims at ~$0.09/claim plus clearinghouse fees.

Visit Practice Fusionpracticefusion.com
10
Office Ally logo

Office Ally

other

Free online portal for medical billing, claims clearinghouse services, and ERA processing tailored for independent healthcare providers.

Overall Rating7.8/10
Features
7.5/10
Ease of Use
8.5/10
Value
9.0/10
Standout Feature

Free real-time eligibility verification across thousands of payers

Office Ally is a web-based medical billing clearinghouse designed for physician practices, enabling electronic claims submission, eligibility verification, ERA posting, and denial management. It supports ANSI 837 formats and connects to thousands of payers, streamlining revenue cycle tasks without requiring software installation. While it offers free basic tools like eligibility checks and claims status, advanced features involve transaction fees, making it a budget-friendly option for billing-focused workflows.

Pros

  • Extremely cost-effective with free eligibility checks and claims status for most payers
  • User-friendly web interface requiring no downloads or IT setup
  • High payer connectivity supporting over 4,000 insurance companies

Cons

  • Limited advanced practice management or EHR integration compared to full suites
  • Customer support can be inconsistent with slower response times
  • Transaction-based fees add up for high-volume practices

Best For

Small to mid-sized physician practices needing an affordable, straightforward billing clearinghouse for claims processing and eligibility without comprehensive PM features.

Pricing

Free for basic eligibility and status checks; claims submission at ~$0.09-$0.15 per claim, with subscriptions starting at $0.25/month per provider for advanced tools.

Visit Office Allyofficeally.com

Conclusion

The reviewed tools showcase a range of strengths, with athenaOne leading as the top choice, offering robust cloud-based features for automating billing, claims processing, and patient payments. Kareo and AdvancedMD stand out as strong alternatives; Kareo excels with integrated claims scrubbing and denial management, while AdvancedMD provides an all-in-one suite for practice management and revenue cycle efficiency. Each platform caters to distinct physician needs, highlighting the diversity of solutions available.

athenaOne logo
Our Top Pick
athenaOne

Explore athenaOne today to experience streamlined billing, reduced administrative burdens, and improved patient payment tracking—key steps toward optimizing your practice’s financial performance.