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Healthcare Medicine

Top 10 Best Patient Case Management Software of 2026

Discover top 10 patient case management software to streamline workflows. Find your best fit now!

Sarah Mitchell

Sarah Mitchell

Feb 11, 2026

10 tools comparedExpert reviewed
Independent evaluation · Unbiased commentary · Updated regularly
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Patient case management software is a cornerstone of modern healthcare, enhancing care coordination, improving patient outcomes, and optimizing operational efficiency. With a wide range of tools tailored to hospitals, clinics, and long-term care settings, choosing the right solution—whether for acute, ambulatory, or post-acute environments—is critical. This guide highlights the top 10 platforms, each distinguished by its unique strengths.

Quick Overview

  1. 1#1: Epic Systems - Comprehensive EHR platform with advanced patient case management, care coordination, and real-time analytics for hospitals and large health systems.
  2. 2#2: Oracle Health (Cerner) - Integrated health IT suite offering robust case management, workflow automation, and interoperability for acute and ambulatory care.
  3. 3#3: athenahealth - Cloud-based EHR and revenue cycle management with patient case tracking, engagement tools, and population health features.
  4. 4#4: eClinicalWorks - EHR system providing patient case management, telehealth integration, and care coordination for practices of all sizes.
  5. 5#5: NextGen Healthcare - Ambulatory EHR with specialty-specific case management, scheduling, and analytics for outpatient providers.
  6. 6#6: MEDITECH - Expanse EHR platform delivering patient case management, clinical decision support, and interoperability for community hospitals.
  7. 7#7: Veradigm (Allscripts) - EHR and practice management software with case tracking, population health, and data analytics capabilities.
  8. 8#8: Kareo - Cloud platform for independent practices offering patient case management, billing, and telehealth in one solution.
  9. 9#9: PointClickCare - SaaS platform for long-term and senior care with comprehensive case management and resident tracking tools.
  10. 10#10: MatrixCare - EHR for post-acute care featuring case management, MDS automation, and care planning workflows.

Tools were selected based on rigorous evaluation of core features (case tracking, interoperability, analytics), usability, operational value, and adaptability to diverse care settings, ensuring a balanced list of industry leaders.

Comparison Table

Explore the core features, usability, and suitability of top Patient Case Management Software with this comparison table, featuring tools like Epic Systems, Oracle Health (Cerner), athenahealth, eClinicalWorks, NextGen Healthcare, and additional platforms. This resource helps readers analyze functionality, care coordination capabilities, and integration needs to identify the best fit for clinical and administrative workflows.

Comprehensive EHR platform with advanced patient case management, care coordination, and real-time analytics for hospitals and large health systems.

Features
9.9/10
Ease
7.8/10
Value
8.9/10

Integrated health IT suite offering robust case management, workflow automation, and interoperability for acute and ambulatory care.

Features
9.5/10
Ease
7.4/10
Value
8.3/10

Cloud-based EHR and revenue cycle management with patient case tracking, engagement tools, and population health features.

Features
9.2/10
Ease
7.8/10
Value
8.0/10

EHR system providing patient case management, telehealth integration, and care coordination for practices of all sizes.

Features
8.7/10
Ease
6.8/10
Value
7.9/10

Ambulatory EHR with specialty-specific case management, scheduling, and analytics for outpatient providers.

Features
8.7/10
Ease
7.6/10
Value
8.0/10
6MEDITECH logo8.1/10

Expanse EHR platform delivering patient case management, clinical decision support, and interoperability for community hospitals.

Features
8.6/10
Ease
7.2/10
Value
7.8/10

EHR and practice management software with case tracking, population health, and data analytics capabilities.

Features
8.2/10
Ease
6.8/10
Value
7.0/10
8Kareo logo8.2/10

Cloud platform for independent practices offering patient case management, billing, and telehealth in one solution.

Features
8.5/10
Ease
8.0/10
Value
7.8/10

SaaS platform for long-term and senior care with comprehensive case management and resident tracking tools.

Features
9.2/10
Ease
7.5/10
Value
7.8/10
10MatrixCare logo8.2/10

EHR for post-acute care featuring case management, MDS automation, and care planning workflows.

Features
8.8/10
Ease
7.5/10
Value
7.8/10
1
Epic Systems logo

Epic Systems

enterprise

Comprehensive EHR platform with advanced patient case management, care coordination, and real-time analytics for hospitals and large health systems.

Overall Rating9.7/10
Features
9.9/10
Ease of Use
7.8/10
Value
8.9/10
Standout Feature

Care Everywhere interoperability network for secure, real-time patient data exchange across thousands of unaffiliated organizations

Epic Systems is a premier electronic health record (EHR) platform with advanced patient case management tools that centralize patient data, care plans, and interdisciplinary coordination. It supports end-to-end case management, including risk stratification, care transitions, referral tracking, and outcome monitoring across inpatient, outpatient, and post-acute settings. Epic's integrated ecosystem ensures real-time collaboration among providers, reducing silos and improving care continuity. With AI-driven insights and analytics, it optimizes resource allocation and population health management.

Pros

  • Seamless integration across EHR, billing, and analytics for holistic case oversight
  • Highly customizable workflows and rule-based automation tailored to complex cases
  • Robust interoperability via Care Everywhere for cross-provider data sharing

Cons

  • Steep learning curve requiring extensive training and onboarding
  • Prohibitively high implementation and customization costs
  • Overkill for small practices due to enterprise-scale complexity

Best For

Large hospitals, health systems, and academic medical centers needing scalable, enterprise-level patient case management.

Pricing

Custom enterprise pricing; implementation often exceeds $1M+ with ongoing annual fees based on users/modules, typically undisclosed publicly.

2
Oracle Health (Cerner) logo

Oracle Health (Cerner)

enterprise

Integrated health IT suite offering robust case management, workflow automation, and interoperability for acute and ambulatory care.

Overall Rating9.1/10
Features
9.5/10
Ease of Use
7.4/10
Value
8.3/10
Standout Feature

Real-time CareAware surveillance platform that integrates clinical alerts with case management for proactive intervention and length-of-stay optimization

Oracle Health (formerly Cerner) is a comprehensive enterprise EHR platform with robust patient case management capabilities, enabling coordinated care planning, utilization review, and discharge management across complex healthcare environments. It integrates clinical data, financials, and operational workflows to support multidisciplinary teams in tracking patient progress and optimizing outcomes. The system leverages Oracle's cloud infrastructure for scalability and advanced analytics to predict case complexities and resource needs.

Pros

  • Highly scalable for large health systems with deep integration of case management into EHR workflows
  • Advanced AI and predictive analytics for risk stratification and care optimization
  • Strong compliance tools for utilization management and regulatory reporting

Cons

  • Steep learning curve and complex interface requiring extensive training
  • Prohibitively high implementation costs and long deployment timelines
  • Less flexible for smaller practices or rapid customization needs

Best For

Large hospitals and integrated health systems needing enterprise-grade, fully integrated patient case management within a comprehensive EHR.

Pricing

Custom enterprise licensing with implementation costs often exceeding $1M+ and annual subscriptions scaling by beds/users, typically quoted individually.

3
athenahealth logo

athenahealth

enterprise

Cloud-based EHR and revenue cycle management with patient case tracking, engagement tools, and population health features.

Overall Rating8.5/10
Features
9.2/10
Ease of Use
7.8/10
Value
8.0/10
Standout Feature

Intelligent case coordination engine that automates workflows, prioritizes tasks, and integrates population health insights for proactive patient management

athenahealth's athenaOne platform is a comprehensive cloud-based EHR and practice management solution that excels in patient case management by centralizing patient records, automating care coordination workflows, and providing tools for tracking treatment plans and outcomes. It integrates scheduling, billing, and telehealth to streamline case handling across providers. The system supports population health management and interoperability with other healthcare systems for efficient case transitions.

Pros

  • Seamless integration of EHR, billing, and case management tools
  • Advanced analytics and reporting for case tracking and outcomes
  • Strong interoperability and mobile access for on-the-go case management

Cons

  • Steep learning curve for new users due to extensive features
  • High subscription costs that may not suit small practices
  • Occasional customization limitations for unique case workflows

Best For

Mid-sized to large medical practices or multi-provider groups seeking an all-in-one platform for integrated patient case management and revenue cycle.

Pricing

Custom subscription pricing starting at around $140-$400 per provider per month, plus implementation fees; quotes required.

Visit athenahealthathenahealth.com
4
eClinicalWorks logo

eClinicalWorks

enterprise

EHR system providing patient case management, telehealth integration, and care coordination for practices of all sizes.

Overall Rating8.1/10
Features
8.7/10
Ease of Use
6.8/10
Value
7.9/10
Standout Feature

Integrated care management suite with AI-driven insights and automated workflows for proactive case monitoring

eClinicalWorks is a comprehensive cloud-based EHR and practice management platform with strong patient case management features, enabling care teams to coordinate cases through shared workflows, task management, and progress tracking. It integrates patient data from multiple sources for holistic case oversight, including care plans, referrals, and population health analytics. The solution supports telehealth and patient engagement tools to enhance case resolution efficiency across providers.

Pros

  • Robust integration with EHR for seamless case data access and updates
  • Advanced care coordination tools including automated alerts and task assignments
  • Scalable for enterprise-level practices with strong population health management

Cons

  • Steep learning curve due to complex interface
  • Reported issues with system performance and occasional outages
  • Customer support response times can be slow for non-enterprise users

Best For

Large multi-provider practices or health systems requiring integrated EHR-based case management with population health capabilities.

Pricing

Quote-based pricing, typically $449+ per provider/month, with additional fees for modules like telehealth and advanced analytics.

Visit eClinicalWorkseclinicalworks.com
5
NextGen Healthcare logo

NextGen Healthcare

enterprise

Ambulatory EHR with specialty-specific case management, scheduling, and analytics for outpatient providers.

Overall Rating8.2/10
Features
8.7/10
Ease of Use
7.6/10
Value
8.0/10
Standout Feature

Population Health Management with predictive analytics for identifying high-risk cases early

NextGen Healthcare is a cloud-based EHR and practice management platform that supports patient case management through integrated tools for care coordination, chronic condition tracking, and referral management. It enables providers to create and monitor care plans, automate workflows for case progression, and leverage population health analytics for proactive interventions. The solution emphasizes interoperability with HIEs and other systems, ensuring comprehensive patient data access across care teams.

Pros

  • Robust care coordination and population health tools for effective case tracking
  • Strong interoperability with external systems and standards like FHIR
  • Integrated revenue cycle management tied to patient cases

Cons

  • Steep learning curve due to extensive feature set
  • Custom pricing can be expensive for small practices
  • Reported occasional glitches in mobile access and reporting

Best For

Mid-sized ambulatory practices and specialty groups needing scalable case management within a full EHR ecosystem.

Pricing

Custom enterprise pricing via quote; typically $300-$600 per provider/month depending on modules and practice size.

6
MEDITECH logo

MEDITECH

enterprise

Expanse EHR platform delivering patient case management, clinical decision support, and interoperability for community hospitals.

Overall Rating8.1/10
Features
8.6/10
Ease of Use
7.2/10
Value
7.8/10
Standout Feature

Real-time interdisciplinary care team collaboration with embedded EHR data and automated length-of-stay predictions

MEDITECH offers a comprehensive electronic health record (EHR) platform with robust patient case management capabilities, enabling care coordination, utilization review, discharge planning, and interdisciplinary team collaboration. Integrated within its Expanse EHR system, it provides real-time access to patient data, risk assessments, and automated workflows to streamline case management processes across acute and ambulatory settings. Widely used in mid-sized hospitals, it supports population health management and compliance with regulatory standards like CMS conditions of participation.

Pros

  • Deep integration with full EHR suite for seamless data access and reduced silos
  • Advanced analytics and reporting for utilization management and outcomes tracking
  • Scalable for mid-sized hospitals with strong support for regulatory compliance

Cons

  • Steep learning curve and less intuitive interface compared to modern cloud-native solutions
  • High upfront implementation costs and lengthy deployment timelines
  • Limited flexibility for rapid customizations without vendor involvement

Best For

Mid-sized hospitals and health systems needing integrated case management tightly coupled with enterprise EHR functionality.

Pricing

Custom enterprise pricing with upfront implementation fees (often $1M+) and annual subscriptions based on beds/users; contact sales for quotes.

Visit MEDITECHmeditech.com
7
Veradigm (Allscripts) logo

Veradigm (Allscripts)

enterprise

EHR and practice management software with case tracking, population health, and data analytics capabilities.

Overall Rating7.6/10
Features
8.2/10
Ease of Use
6.8/10
Value
7.0/10
Standout Feature

Access to the Veradigm Network's massive clinical data repository for benchmarking case outcomes against national benchmarks

Veradigm (formerly Allscripts) provides patient case management software integrated within its broader EHR and healthcare IT ecosystem, enabling care teams to coordinate complex patient cases efficiently. It supports features like care plan development, risk stratification, automated workflows, and real-time tracking of patient progress across providers. The platform leverages Veradigm's extensive clinical data network for population health insights and outcome benchmarking. Ideal for supporting value-based care and chronic disease management.

Pros

  • Seamless integration with EHR and revenue cycle management
  • Powerful analytics and population health tools for case insights
  • Scalable for enterprise-level healthcare organizations

Cons

  • Steep learning curve and extensive training required
  • High implementation and customization costs
  • Less intuitive interface compared to modern SaaS alternatives

Best For

Mid-to-large healthcare providers and hospitals needing robust, integrated case management within an enterprise EHR system.

Pricing

Custom enterprise pricing via quote; typically $400-$800 per provider/month including modules, with high upfront implementation fees.

8
Kareo logo

Kareo

specialized

Cloud platform for independent practices offering patient case management, billing, and telehealth in one solution.

Overall Rating8.2/10
Features
8.5/10
Ease of Use
8.0/10
Value
7.8/10
Standout Feature

Revenue Cycle Intelligence that automatically optimizes billing codes and claims directly from patient case documentation

Kareo is a cloud-based platform tailored for independent medical practices, providing integrated electronic health records (EHR), practice management, and revenue cycle management tools. It excels in patient case management by enabling streamlined scheduling, clinical documentation, care coordination, and patient engagement through portals and telehealth. The software automates workflows from patient intake to billing, helping practices track cases efficiently while ensuring compliance and revenue optimization.

Pros

  • Strong integration of EHR with billing for comprehensive case tracking
  • User-friendly interface with mobile access and telehealth capabilities
  • Robust patient engagement tools including portals and automated reminders

Cons

  • Pricing can be steep for very small practices
  • Limited advanced customization options for complex workflows
  • Customer support response times can vary

Best For

Ideal for small to mid-sized independent medical practices seeking an all-in-one solution for patient case management, billing, and practice operations.

Pricing

Subscription-based; starts at $160/provider/month for billing, $300+/provider/month for EHR + practice management bundles (billed annually).

Visit Kareokareo.com
9
PointClickCare logo

PointClickCare

specialized

SaaS platform for long-term and senior care with comprehensive case management and resident tracking tools.

Overall Rating8.4/10
Features
9.2/10
Ease of Use
7.5/10
Value
7.8/10
Standout Feature

Unified Data Platform for seamless aggregation and real-time sharing of patient data across care continuum partners

PointClickCare is a leading cloud-based EHR and EMR platform specialized for long-term care, senior living, and post-acute facilities, providing comprehensive patient case management tools. It enables clinical documentation, individualized care planning, medication administration, billing, and regulatory reporting in a single system. The software emphasizes interoperability, real-time analytics, and mobile access to support coordinated care delivery across multidisciplinary teams.

Pros

  • Tailored workflows for long-term care including MDS 3.0 and PDPM compliance
  • Strong interoperability with pharmacies, labs, and hospitals via unified data platform
  • Advanced analytics and predictive insights for care optimization

Cons

  • Steep learning curve and complex interface for new users
  • High upfront implementation costs and customization fees
  • Occasional performance lags in high-volume environments

Best For

Large skilled nursing facilities and long-term/post-acute care providers requiring robust, compliant case management with deep integrations.

Pricing

Custom enterprise pricing based on facility size, beds, and modules; typically $500-$2,000+ per month per facility plus implementation fees.

Visit PointClickCarepointclickcare.com
10
MatrixCare logo

MatrixCare

specialized

EHR for post-acute care featuring case management, MDS automation, and care planning workflows.

Overall Rating8.2/10
Features
8.8/10
Ease of Use
7.5/10
Value
7.8/10
Standout Feature

Unified platform spanning the post-acute care continuum with seamless MDS 3.0 and PDPM reimbursement automation

MatrixCare is a comprehensive EHR and patient management platform tailored for post-acute care, including skilled nursing facilities, home health, hospice, and senior living. It facilitates patient case management through integrated clinical documentation, individualized care planning, interdisciplinary coordination, and regulatory compliance tools like MDS 3.0 assessments. The software also streamlines billing, revenue cycle management, and analytics to support operational efficiency across the care continuum.

Pros

  • Robust integration of clinical, financial, and operational workflows
  • Advanced compliance tools for CMS and state regulations
  • Scalable platform with strong analytics and reporting capabilities

Cons

  • Steep learning curve and complex initial setup
  • Higher cost structure for smaller facilities
  • Occasional user reports of interface lag and customization needs

Best For

Large post-acute care providers like skilled nursing facilities and home health agencies needing an enterprise-grade solution for case management and revenue optimization.

Pricing

Quote-based enterprise pricing, typically $150-$350 per bed/month depending on modules, facility size, and deployment (cloud or on-premise).

Visit MatrixCarematrixcare.com

Conclusion

The top patient case management software options include Epic Systems as the leading choice, offering comprehensive EHR tools, advanced care coordination, and real-time analytics for large health systems. Oracle Health (Cerner) stands out for its integrated IT suite and workflow automation, while athenahealth excels in cloud-based solutions and patient engagement—each catering to distinct needs. Together, these tools showcase the breadth of innovation in healthcare IT.

Epic Systems logo
Our Top Pick
Epic Systems

Explore Epic Systems first for a comprehensive, end-to-end case management solution tailored to your organization's scale. For specific focus areas, Oracle Health (Cerner) or athenahealth offer strong alternatives, but Epic leads as the top pick for integrated care coordination and analytical power.