Top 10 Best Patient Billing Software of 2026

Kareo is a cloud-based medical billing and revenue cycle management platform designed specifically for independent healthcare practices, offering end-to-end patient billing solutions from claims submission to payment collection. It automates patient statements, online payments, denial management, and eligibility verification to streamline revenue workflows. Integrated with EHR and practice management tools, Kareo helps practices maximize reimbursements while minimizing administrative overhead.

AdvancedMD is a comprehensive cloud-based practice management platform with robust patient billing capabilities, automating claims submission, payment posting, and denial management to optimize revenue cycles. It integrates seamlessly with EHR and scheduling for accurate charge capture and patient statements. The software supports online patient payments, eligibility verification, and detailed financial reporting, making it ideal for medical practices handling complex billing workflows.

athenahealth is a cloud-based electronic health record (EHR) and practice management platform with robust patient billing capabilities through its athenaOne Revenue Cycle Management suite. It automates claims submission, eligibility verification, patient statements, and payment posting to streamline billing workflows and reduce administrative burdens. The software provides denial management tools, analytics for revenue optimization, and patient self-service portals for online payments.

DrChrono is a cloud-based EHR and practice management platform with integrated patient billing features designed for medical practices. It automates key billing processes including insurance claims submission, eligibility checks, denial management, and patient payment processing via a patient portal. The system supports electronic remittance advice (ERA) posting and customizable statements, ensuring efficient revenue cycle management.

eClinicalWorks is a comprehensive electronic health records (EHR) and practice management platform with integrated patient billing capabilities designed for medical practices. It handles the full revenue cycle, including claims submission, eligibility verification, denial management, patient statements, and online payments through its Healow patient portal. The software automates billing workflows to reduce errors and accelerate reimbursements, making it suitable for multi-specialty practices.

NextGen Healthcare provides a robust patient billing solution as part of its integrated EHR and practice management platform, specializing in revenue cycle management for ambulatory care providers. It automates claims processing, denial management, payment posting, and patient collections with advanced analytics and EDI capabilities. The system supports complex multi-specialty billing workflows while ensuring HIPAA compliance and interoperability.

Waystar is a comprehensive revenue cycle management (RCM) platform specializing in patient billing for healthcare providers, offering tools for accurate patient estimates, claims processing, denial management, and payment collection. Its patient billing solutions include digital statements, self-service portals, flexible payment plans, and integrated analytics to optimize collections and reduce A/R days. Designed for scalability, Waystar integrates seamlessly with major EHRs and PMS systems, helping large organizations streamline financial operations from patient access to final payment.

Practice Fusion is a cloud-based electronic health record (EHR) system that includes integrated patient billing features, enabling practices to generate superbills, submit electronic claims to over 2,000 payers, and manage patient payments and statements seamlessly within the EHR workflow. Designed primarily for small to mid-sized practices, it automates billing processes like claims scrubbing and denial management to reduce errors and speed up reimbursements. While not a standalone billing solution, its tight integration with clinical documentation makes it efficient for practices already using the platform.

CureMD is a cloud-based EHR and practice management platform with integrated patient billing software that automates revenue cycle management for healthcare providers. It supports electronic claims submission to over 4,000 payers, real-time insurance eligibility verification, denial management, and patient payment processing via a secure portal. The solution offers customizable reporting and analytics to track accounts receivable and optimize collections.

PracticeSuite is an integrated practice management and billing software tailored for healthcare providers, focusing on streamlining patient billing workflows. It automates insurance claims submission, payment posting, denial management, and patient statement generation, while integrating with EHR and scheduling modules. The platform supports eligibility verification, AR management, and reporting to optimize revenue cycles for medical practices.