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Healthcare Medicine

Top 10 Best Pathology Reporting Software of 2026

Explore the top pathology reporting software tools for efficient diagnostics. Compare features, find the best fit – start now!

Sarah Mitchell

Sarah Mitchell

Feb 11, 2026

10 tools comparedExpert reviewed
Independent evaluation · Unbiased commentary · Updated regularly
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Pathology reporting software is a cornerstone of modern clinical diagnostics, driving accuracy, efficiency, and collaboration across labs and healthcare systems. With a robust range of tools—from integrated LIS platforms to AI-powered solutions—selecting the right software is critical for optimizing workflows and meeting evolving clinical demands. Below, we highlight the top 10 options, each designed to address diverse needs in anatomic, clinical, and molecular pathology.

Quick Overview

  1. 1#1: Epic Beaker Pathology - Comprehensive laboratory information system integrating anatomic pathology workflows, synoptic reporting, and EHR connectivity for efficient case management.
  2. 2#2: Cerner PathNet - Advanced anatomic pathology solution with voice-enabled reporting, multimedia support, and seamless integration into hospital EHR systems.
  3. 3#3: Sunquest PowerPath - Enterprise-grade anatomic pathology platform featuring synoptic templates, digital slide integration, and automated report generation.
  4. 4#4: NovoPath 360 - Cloud-native pathology information system optimizing accessioning, grossing, sign-out, and CAP-compliant reporting workflows.
  5. 5#5: Psyche ASCEND - Unified LIS for anatomic, clinical, and molecular pathology with customizable reporting, quality control, and billing integration.
  6. 6#6: Proscia Concentriq - Digital pathology platform combining image management, AI algorithms, and collaborative tools for streamlined reporting and diagnostics.
  7. 7#7: Sectra Pathology - Integrated digital pathology solution for whole-slide imaging, AI-assisted analysis, and diagnostic reporting across distributed teams.
  8. 8#8: Philips IntelliSite Pathology - End-to-end digital pathology workflow system supporting scanning, AI applications, case management, and standardized reporting.
  9. 9#9: PathAI - AI-powered pathology platform providing diagnostic assistance, case prioritization, and enhanced accuracy in reporting complex cases.
  10. 10#10: Paige - AI diagnostics platform accelerating pathology workflows with automated image analysis and preliminary report generation for faster sign-out.

We prioritized tools based on their comprehensive feature sets (including AI assistance, digital slide integration, and CAP compliance), ease of use for clinical and lab teams, seamless EHR integration, and overall value, ensuring a balanced ranking that caters to varied operational and diagnostic requirements.

Comparison Table

This comparison table assesses critical features, workflow integration, and performance of leading pathology reporting software, including tools like Epic Beaker Pathology, Cerner PathNet, Sunquest PowerPath, NovoPath 360, and Psyche ASCEND. By analyzing aspects such as reporting speed, interoperability, and user-friendliness, readers can identify the platform that best suits their practice's unique requirements.

Comprehensive laboratory information system integrating anatomic pathology workflows, synoptic reporting, and EHR connectivity for efficient case management.

Features
9.7/10
Ease
8.2/10
Value
8.8/10

Advanced anatomic pathology solution with voice-enabled reporting, multimedia support, and seamless integration into hospital EHR systems.

Features
9.5/10
Ease
7.8/10
Value
8.4/10

Enterprise-grade anatomic pathology platform featuring synoptic templates, digital slide integration, and automated report generation.

Features
9.0/10
Ease
7.5/10
Value
7.8/10

Cloud-native pathology information system optimizing accessioning, grossing, sign-out, and CAP-compliant reporting workflows.

Features
9.2/10
Ease
8.1/10
Value
8.4/10

Unified LIS for anatomic, clinical, and molecular pathology with customizable reporting, quality control, and billing integration.

Features
8.5/10
Ease
7.8/10
Value
7.6/10

Digital pathology platform combining image management, AI algorithms, and collaborative tools for streamlined reporting and diagnostics.

Features
8.7/10
Ease
7.9/10
Value
7.6/10

Integrated digital pathology solution for whole-slide imaging, AI-assisted analysis, and diagnostic reporting across distributed teams.

Features
9.2/10
Ease
7.8/10
Value
7.9/10

End-to-end digital pathology workflow system supporting scanning, AI applications, case management, and standardized reporting.

Features
9.1/10
Ease
7.6/10
Value
7.8/10
9PathAI logo8.6/10

AI-powered pathology platform providing diagnostic assistance, case prioritization, and enhanced accuracy in reporting complex cases.

Features
9.3/10
Ease
7.9/10
Value
7.7/10
10Paige logo7.8/10

AI diagnostics platform accelerating pathology workflows with automated image analysis and preliminary report generation for faster sign-out.

Features
8.5/10
Ease
7.2/10
Value
7.4/10
1
Epic Beaker Pathology logo

Epic Beaker Pathology

enterprise

Comprehensive laboratory information system integrating anatomic pathology workflows, synoptic reporting, and EHR connectivity for efficient case management.

Overall Rating9.4/10
Features
9.7/10
Ease of Use
8.2/10
Value
8.8/10
Standout Feature

Deep native integration with Epic's EHR ecosystem for real-time pathology data sharing and multidisciplinary case review

Epic Beaker Pathology is a comprehensive laboratory information system (LIS) module within the Epic EHR platform, designed specifically for pathology workflows including anatomic, clinical, and molecular pathology. It handles specimen accessioning, gross examination, microscopic review, case finalization, and report generation with support for synoptic reporting and regulatory compliance. The software excels in integrating pathology data seamlessly into the broader patient record, enabling multidisciplinary collaboration and real-time updates across clinical teams.

Pros

  • Seamless integration with Epic EHR for unified patient data and workflows
  • Advanced pathology tools including synoptic reporting, voice recognition, and CAP-compliant checklists
  • Robust customization, analytics, and compliance features for high-volume labs

Cons

  • High upfront implementation costs and lengthy deployment timeline
  • Steep learning curve due to complex interface and extensive configuration
  • Vendor lock-in limits interoperability with non-Epic systems

Best For

Large hospitals and integrated health systems using Epic EHR that need a scalable, enterprise-grade pathology reporting solution.

Pricing

Custom enterprise licensing starting at millions annually, based on organization size, user count, and modules; no public pricing available.

2
Cerner PathNet logo

Cerner PathNet

enterprise

Advanced anatomic pathology solution with voice-enabled reporting, multimedia support, and seamless integration into hospital EHR systems.

Overall Rating9.1/10
Features
9.5/10
Ease of Use
7.8/10
Value
8.4/10
Standout Feature

Tight bidirectional integration with Cerner Millennium EHR, enabling real-time pathology data flow across clinical workflows

Cerner PathNet is a comprehensive anatomic pathology information system designed to manage the full pathology workflow, from specimen accessioning and grossing to microscopic examination, reporting, and distribution. It supports advanced features like synoptic reporting, CAP checklist compliance, multimedia integration for images and voice dictation, and seamless connectivity with Cerner's Millennium EHR platform. PathNet excels in high-volume labs by automating workflows, ensuring regulatory compliance, and enabling digital pathology capabilities.

Pros

  • Seamless integration with Cerner Millennium EHR for unified patient data
  • Robust synoptic reporting and CAP/eCC protocol support
  • Advanced workflow automation and digital pathology image management

Cons

  • Steep learning curve and complex implementation process
  • High upfront and ongoing costs for enterprise deployment
  • Limited flexibility for non-Cerner environments or smaller labs

Best For

Large hospitals and health systems already using Cerner Millennium that require enterprise-grade pathology reporting and workflow integration.

Pricing

Custom enterprise licensing with implementation fees; annual costs often exceed $500,000+ for mid-to-large facilities, based on modules and user volume.

3
Sunquest PowerPath logo

Sunquest PowerPath

enterprise

Enterprise-grade anatomic pathology platform featuring synoptic templates, digital slide integration, and automated report generation.

Overall Rating8.2/10
Features
9.0/10
Ease of Use
7.5/10
Value
7.8/10
Standout Feature

Integrated voice productivity suite with Dragon Medical integration for hands-free dictation and structured reporting.

Sunquest PowerPath is a robust anatomic pathology laboratory information system (AP-LIS) that manages the full workflow from specimen accessioning and grossing to microscopic review, reporting, and case distribution. It supports synoptic reporting, voice recognition for dictation, customizable templates, and integration with digital pathology scanners and EMRs. Designed for high-volume pathology labs, it ensures regulatory compliance and streamlines collaboration among pathologists, histotechnologists, and clinicians.

Pros

  • Comprehensive workflow automation for accessioning, reporting, and distribution
  • Advanced voice recognition and synoptic reporting tools for efficiency
  • Strong integrations with EMRs, scanners, and digital pathology systems

Cons

  • Steep learning curve and dated interface in some modules
  • Complex implementation requiring significant IT resources
  • High enterprise-level pricing with custom contracts

Best For

Mid-to-large anatomic pathology labs needing a full-featured LIS with robust workflow and compliance tools.

Pricing

Custom enterprise pricing, typically $200K+ annually for mid-sized labs including implementation and support.

Visit Sunquest PowerPathsunquestinfo.com
4
NovoPath 360 logo

NovoPath 360

enterprise

Cloud-native pathology information system optimizing accessioning, grossing, sign-out, and CAP-compliant reporting workflows.

Overall Rating8.7/10
Features
9.2/10
Ease of Use
8.1/10
Value
8.4/10
Standout Feature

Integrated 360° workflow uniting grossing stations, digital slide review, synoptic reporting, and AI-assisted triage in a single unified platform

NovoPath 360 is a comprehensive cloud-based pathology information system (LIS/AP) that streamlines the entire anatomic pathology workflow, from accessioning and grossing to advanced reporting and case distribution. It excels in pathology reporting with customizable templates, CAP-compliant synoptic reporting, voice recognition integration, and seamless connectivity to digital pathology scanners and EMRs. The platform supports multi-site labs with real-time collaboration, quality assurance tools, and scalability for high-volume operations.

Pros

  • Robust synoptic and structured reporting tools ensure regulatory compliance and efficiency
  • Strong integrations with digital pathology, EMRs, and scanners for end-to-end workflow
  • Cloud-based accessibility with mobile support for remote review and collaboration

Cons

  • Steep learning curve due to extensive feature set and customization options
  • Enterprise pricing may be prohibitive for small or independent practices
  • Some advanced AI and analytics features require additional modules or setup

Best For

Mid-to-large pathology labs and hospital systems needing a scalable, integrated platform for high-volume reporting and workflow management.

Pricing

Custom enterprise SaaS pricing based on lab size, users, and modules; typically starts at $10,000+ annually with per-case or subscription models—contact for quote.

Visit NovoPath 360novopath.com
5
Psyche ASCEND logo

Psyche ASCEND

enterprise

Unified LIS for anatomic, clinical, and molecular pathology with customizable reporting, quality control, and billing integration.

Overall Rating8.1/10
Features
8.5/10
Ease of Use
7.8/10
Value
7.6/10
Standout Feature

Integrated voice pathology with AI-assisted grossing and synoptic report generation

Psyche ASCEND from Psyche Systems is a cloud-based anatomic pathology solution that streamlines lab workflows from accessioning and grossing to final reporting. It provides tools for synoptic reporting, voice recognition dictation, customizable templates, and compliance with CAP protocols. The software integrates with LIS, EMRs, and offers web accessibility for pathologists to generate accurate, structured pathology reports efficiently.

Pros

  • Comprehensive synoptic and structured reporting tools
  • Seamless voice-to-text integration for dictation
  • Strong workflow automation and EMR integrations

Cons

  • Initial configuration can be complex for smaller labs
  • Limited advanced AI analytics compared to top competitors
  • Pricing lacks transparency without a quote

Best For

Mid-sized pathology labs seeking a reliable, scalable solution for high-volume reporting and compliance.

Pricing

Custom enterprise pricing based on lab size and modules; typically requires contacting psychsystems.com for a quote.

Visit Psyche ASCENDpsychsystems.com
6
Proscia Concentriq logo

Proscia Concentriq

specialized

Digital pathology platform combining image management, AI algorithms, and collaborative tools for streamlined reporting and diagnostics.

Overall Rating8.1/10
Features
8.7/10
Ease of Use
7.9/10
Value
7.6/10
Standout Feature

AI Apps Marketplace allowing seamless deployment and integration of third-party AI models for pathology-specific analysis

Proscia Concentriq is a cloud-native digital pathology platform that enables pathologists to manage, analyze, and report on whole slide images (WSI) efficiently. It integrates AI-driven tools for image analysis, workflow automation, and collaborative case review to support primary diagnostics and research. The software streamlines pathology reporting by connecting scanners, LIS systems, and reporting modules into a unified environment.

Pros

  • Extensive AI Apps Marketplace for customizable algorithms
  • Scalable cloud architecture for high-volume labs
  • Seamless integration with scanners, LIS, and EMR systems

Cons

  • Steep learning curve for non-digital-native users
  • Enterprise pricing may be prohibitive for small labs
  • Limited on-premise deployment options

Best For

Mid-to-large pathology labs or hospitals needing scalable AI-enhanced digital pathology workflows.

Pricing

Custom enterprise licensing; typically subscription-based with per-slide or per-user fees—contact sales for quotes.

7
Sectra Pathology logo

Sectra Pathology

enterprise

Integrated digital pathology solution for whole-slide imaging, AI-assisted analysis, and diagnostic reporting across distributed teams.

Overall Rating8.6/10
Features
9.2/10
Ease of Use
7.8/10
Value
7.9/10
Standout Feature

Unified Viewer that displays pathology slides alongside radiology images in a single platform for multidisciplinary review

Sectra Pathology is an enterprise-grade digital pathology solution that provides whole slide imaging, advanced case management, and integrated reporting tools for pathology labs. It enables pathologists to capture, store, view, and annotate high-resolution digital slides while generating structured synoptic reports compliant with CAP protocols. The platform excels in seamless integration with Sectra's radiology PACS, fostering multidisciplinary collaboration, and supports AI-assisted diagnostics for improved efficiency.

Pros

  • Seamless integration with radiology PACS for unified workflows
  • High-performance whole slide viewer with advanced annotation tools
  • Robust security, scalability, and regulatory compliance (FDA-cleared)

Cons

  • High upfront costs and complex implementation
  • Steep learning curve for non-enterprise users
  • Limited flexibility for small labs without IT support

Best For

Large hospitals and academic centers needing integrated radiology-pathology solutions for high-volume case management.

Pricing

Enterprise pricing on request; typically $50,000+ annually per site plus hardware/scanning costs.

8
Philips IntelliSite Pathology logo

Philips IntelliSite Pathology

enterprise

End-to-end digital pathology workflow system supporting scanning, AI applications, case management, and standardized reporting.

Overall Rating8.4/10
Features
9.1/10
Ease of Use
7.6/10
Value
7.8/10
Standout Feature

FDA 510(k) clearance for primary diagnostic use of digital pathology images

Philips IntelliSite Pathology is a comprehensive digital pathology platform that scans glass slides into high-resolution whole-slide images, enabling pathologists to perform remote reviews, annotations, and diagnostics. It integrates workflow management, case distribution, and reporting tools with LIS/HIS systems for streamlined pathology reporting. The solution is FDA-cleared for primary diagnosis, supporting both routine and complex cases in high-volume labs.

Pros

  • FDA-cleared for primary diagnosis with whole-slide imaging
  • Robust workflow automation and collaboration tools
  • High-resolution imaging and scalable enterprise deployment

Cons

  • High upfront costs for scanners and full implementation
  • Steep learning curve for non-digital native users
  • Limited native AI analytics compared to competitors

Best For

Mid-to-large pathology labs transitioning to digital workflows and needing FDA-compliant primary diagnostics.

Pricing

Enterprise licensing with custom quotes; starts at $500K+ for full system including scanners and software.

9
PathAI logo

PathAI

specialized

AI-powered pathology platform providing diagnostic assistance, case prioritization, and enhanced accuracy in reporting complex cases.

Overall Rating8.6/10
Features
9.3/10
Ease of Use
7.9/10
Value
7.7/10
Standout Feature

FDA-cleared AI models that provide quantifiable diagnostic support with peer-reviewed concordance rates exceeding 95% for key indications

PathAI is an AI-driven pathology platform that leverages machine learning to analyze whole-slide images, assisting pathologists in diagnosing diseases like cancer with greater accuracy and efficiency. It offers tools such as AISight for case prioritization, AI model inferences, and quality control to streamline workflows and reduce diagnostic variability. Primarily used in clinical labs, it integrates with digital pathology scanners to support reporting by providing probabilistic scores and annotations directly on slides.

Pros

  • FDA-cleared AI algorithms for high accuracy in cancer diagnostics like breast and prostate
  • Significant workflow efficiency gains through case prioritization and batch processing
  • Robust integration with leading digital pathology scanners and lab information systems

Cons

  • High enterprise-level pricing limits accessibility for smaller labs
  • Requires substantial upfront investment in digital pathology infrastructure
  • Feature set focused on AI augmentation rather than full end-to-end reporting tools

Best For

Mid-to-large clinical pathology labs looking to augment diagnostic accuracy with AI for high-volume cancer cases.

Pricing

Enterprise subscription model, typically $0.50-$2 per slide analyzed or annual contracts starting at $100K+; custom quotes required.

Visit PathAIpathai.com
10
Paige logo

Paige

specialized

AI diagnostics platform accelerating pathology workflows with automated image analysis and preliminary report generation for faster sign-out.

Overall Rating7.8/10
Features
8.5/10
Ease of Use
7.2/10
Value
7.4/10
Standout Feature

Paige Prostate Suite: FDA-approved AI for detecting and grading prostate cancer with full-slide analysis and 93%+ sensitivity.

Paige (paige.ai) is an AI-powered digital pathology platform that assists pathologists in analyzing whole-slide images for cancer diagnostics, particularly in prostate, breast, and other tissues. It uses deep learning models to detect tumors, quantify biomarkers, and provide actionable insights that can accelerate pathology reporting workflows. The platform integrates AI annotations directly into lab information systems, enabling faster and more consistent report generation while maintaining pathologist oversight.

Pros

  • FDA-cleared AI models for high-accuracy tumor detection and quantification
  • Cloud-based scalability for high-volume labs
  • Streamlines reporting with automated annotations and measurements

Cons

  • Limited to specific cancer types like prostate and breast
  • Requires compatible digital slide scanners and integration setup
  • Enterprise pricing lacks transparency and can be costly

Best For

Mid-to-large oncology pathology labs seeking AI augmentation for diagnostic accuracy in cancer reporting.

Pricing

Custom enterprise licensing; subscription-based, typically starting at high five-figures annually per lab—contact for quote.

Visit Paigepaige.ai

Conclusion

The top pathology reporting software reviewed excel in streamlining workflows and enhancing accuracy, with Epic Beaker Pathology leading as the top choice—boasting comprehensive integration of anatomic pathology, synoptic reporting, and EHR connectivity. Cerner PathNet and Sunquest PowerPath closely follow, offering unique strengths: Cerner’s voice-enabled and multimedia support, and Sunquest’s digital slide integration and automated report generation, each tailored to distinct clinical needs. Together, these tools demonstrate the breadth of innovation in modern pathology reporting, ensuring practices can find the ideal fit for their unique workflows.

Epic Beaker Pathology logo
Our Top Pick
Epic Beaker Pathology

Don’t miss the opportunity to experience Epic Beaker Pathology’s capabilities and explore how it can transform your reporting efficiency, or discover Cerner PathNet and Sunquest PowerPath for alternative solutions that align with your specific practice requirements.