Quick Overview
- 1#1: Sunquest PowerPath - Comprehensive enterprise anatomic pathology information system for workflow automation, case management, and synoptic reporting.
- 2#2: Epic Beaker - Integrated anatomic pathology module within Epic's EHR platform for seamless lab workflows and result reporting.
- 3#3: Cerner PathNet - Advanced pathology LIS supporting anatomic, molecular, and clinical workflows with deep EHR integration.
- 4#4: NovoPath 360 - Cloud-based anatomic pathology platform with AI-enhanced reporting and customizable workflows.
- 5#5: SoftPath Dx - Robust anatomic pathology software featuring voice dictation, synoptic templates, and grossing tools.
- 6#6: Psyche PATH - Integrated pathology information system for accessioning, tracking, and multimedia reporting in labs.
- 7#7: CGM Anatomic Pathology - Full-featured AP solution with case management, quality control, and interoperability standards support.
- 8#8: XIFIN LIS - Laboratory information system optimized for pathology billing, workflows, and compliance management.
- 9#9: Proscia Concentriq - Digital pathology platform for whole slide imaging, AI analysis, and remote collaboration.
- 10#10: PathAI - AI-driven pathology assistant for improving diagnostic accuracy and lab efficiency.
Tools were selected based on feature depth, usability, interoperability with EHR systems, and value, ensuring they address the varied needs of anatomic, molecular, and clinical pathology workflows.
Comparison Table
Pathology lab software plays a vital role in optimizing processes, ensuring precision, and supporting efficient patient care. This comparison table explores key features of leading tools such as Sunquest PowerPath, Epic Beaker, Cerner PathNet, NovoPath 360, SoftPath Dx, and more, helping readers identify the most suitable solution for their lab's specific requirements.
| # | Tool | Category | Overall | Features | Ease of Use | Value |
|---|---|---|---|---|---|---|
| 1 | Sunquest PowerPath Comprehensive enterprise anatomic pathology information system for workflow automation, case management, and synoptic reporting. | enterprise | 9.7/10 | 9.9/10 | 8.7/10 | 9.4/10 |
| 2 | Epic Beaker Integrated anatomic pathology module within Epic's EHR platform for seamless lab workflows and result reporting. | enterprise | 9.2/10 | 9.8/10 | 7.4/10 | 8.1/10 |
| 3 | Cerner PathNet Advanced pathology LIS supporting anatomic, molecular, and clinical workflows with deep EHR integration. | enterprise | 8.4/10 | 9.1/10 | 7.2/10 | 7.9/10 |
| 4 | NovoPath 360 Cloud-based anatomic pathology platform with AI-enhanced reporting and customizable workflows. | specialized | 8.4/10 | 8.8/10 | 8.0/10 | 8.2/10 |
| 5 | SoftPath Dx Robust anatomic pathology software featuring voice dictation, synoptic templates, and grossing tools. | specialized | 8.1/10 | 8.6/10 | 7.7/10 | 7.9/10 |
| 6 | Psyche PATH Integrated pathology information system for accessioning, tracking, and multimedia reporting in labs. | specialized | 8.3/10 | 8.7/10 | 8.1/10 | 7.9/10 |
| 7 | CGM Anatomic Pathology Full-featured AP solution with case management, quality control, and interoperability standards support. | enterprise | 8.1/10 | 8.5/10 | 7.6/10 | 7.8/10 |
| 8 | XIFIN LIS Laboratory information system optimized for pathology billing, workflows, and compliance management. | enterprise | 8.4/10 | 9.1/10 | 7.6/10 | 8.2/10 |
| 9 | Proscia Concentriq Digital pathology platform for whole slide imaging, AI analysis, and remote collaboration. | specialized | 8.4/10 | 9.2/10 | 7.8/10 | 7.5/10 |
| 10 | PathAI AI-driven pathology assistant for improving diagnostic accuracy and lab efficiency. | general_ai | 8.5/10 | 9.2/10 | 7.8/10 | 7.5/10 |
Comprehensive enterprise anatomic pathology information system for workflow automation, case management, and synoptic reporting.
Integrated anatomic pathology module within Epic's EHR platform for seamless lab workflows and result reporting.
Advanced pathology LIS supporting anatomic, molecular, and clinical workflows with deep EHR integration.
Cloud-based anatomic pathology platform with AI-enhanced reporting and customizable workflows.
Robust anatomic pathology software featuring voice dictation, synoptic templates, and grossing tools.
Integrated pathology information system for accessioning, tracking, and multimedia reporting in labs.
Full-featured AP solution with case management, quality control, and interoperability standards support.
Laboratory information system optimized for pathology billing, workflows, and compliance management.
Digital pathology platform for whole slide imaging, AI analysis, and remote collaboration.
AI-driven pathology assistant for improving diagnostic accuracy and lab efficiency.
Sunquest PowerPath
enterpriseComprehensive enterprise anatomic pathology information system for workflow automation, case management, and synoptic reporting.
Integrated voice productivity suite with structured synoptic reporting for rapid, compliant case finalization
Sunquest PowerPath is a comprehensive anatomic pathology laboratory information system (AP-LIS) that manages the entire workflow from specimen collection and accessioning to case sign-out and reporting. It excels in supporting histopathology, cytology, molecular pathology, and surgical pathology with features like synoptic reporting, multimedia case documentation, and seamless integration with EHRs and digital pathology scanners. Designed for high-volume labs, it ensures regulatory compliance (e.g., CAP, CLIA) while optimizing turnaround times and pathologist productivity through voice recognition and advanced workflow engines.
Pros
- End-to-end workflow automation tailored specifically for anatomic pathology
- Superior integration capabilities with EHRs, LIS middleware, instruments, and digital pathology systems
- Advanced productivity tools like voice dictation, synoptic reporting, and grossing workstations
Cons
- Complex implementation requiring significant upfront time and resources
- Steep learning curve for non-enterprise users
- Premium pricing may not suit small or low-volume labs
Best For
Large hospital-based pathology departments and high-volume reference labs needing robust, scalable enterprise-grade AP-LIS.
Pricing
Custom enterprise licensing; typically $150,000+ annually based on lab size, modules, and support.
Epic Beaker
enterpriseIntegrated anatomic pathology module within Epic's EHR platform for seamless lab workflows and result reporting.
Fully integrated anatomic pathology workflow with synoptic reporting and CAP checklist automation directly linked to EHR patient charts
Epic Beaker is a comprehensive laboratory information system (LIS) from Epic Systems, tailored for pathology labs with modules for anatomic pathology (AP), clinical pathology (CP), molecular diagnostics, and blood banking. It manages the full workflow from specimen accessioning and grossing to sign-out and reporting, with seamless integration into Epic's electronic health record (EHR) platform. Beaker excels in large-scale environments by providing advanced analytics, compliance tools, and support for digital pathology.
Pros
- Seamless integration with Epic EHR for unified patient data and reduced errors
- Comprehensive support for all pathology disciplines including AP, CP, and genomics
- Robust regulatory compliance, audit trails, and advanced reporting capabilities
Cons
- Steep learning curve and lengthy implementation (often 1-2 years)
- High upfront costs and ongoing fees unsuitable for small labs
- Limited flexibility for non-Epic integrations or customizations
Best For
Large hospital networks and academic medical centers already invested in the Epic ecosystem seeking enterprise-grade pathology management.
Pricing
Custom enterprise pricing; typically involves multi-million-dollar implementation fees plus annual subscriptions based on bed size and volume (not publicly listed).
Cerner PathNet
enterpriseAdvanced pathology LIS supporting anatomic, molecular, and clinical workflows with deep EHR integration.
Tight bidirectional integration with Cerner Millennium EHR, enabling real-time pathology results within the clinician's workflow
Cerner PathNet is a robust anatomic pathology laboratory information system (LIS) that manages the full spectrum of pathology workflows, from specimen accessioning and grossing to microscopic examination, reporting, and case distribution. It excels in handling complex cases with support for multimedia integration, synoptic reporting, and CAP-compliant protocols. Deeply integrated with Cerner's Millennium EHR platform, PathNet ensures seamless data flow across clinical and laboratory environments, making it ideal for enterprise-scale operations.
Pros
- Seamless integration with Cerner Millennium EHR for unified patient data
- Comprehensive workflow automation including synoptic reporting and image management
- Scalable for high-volume labs with advanced analytics and compliance tools
Cons
- Steep learning curve and complex implementation process
- High enterprise-level pricing not suitable for small labs
- Limited flexibility for non-Cerner environments without custom integrations
Best For
Large hospital systems and academic medical centers already invested in the Cerner ecosystem seeking enterprise-grade pathology management.
Pricing
Enterprise subscription model with customized pricing based on modules, user count, and organization size; typically starts at $100K+ annually for mid-sized implementations—contact Cerner for quotes.
NovoPath 360
specializedCloud-based anatomic pathology platform with AI-enhanced reporting and customizable workflows.
AI-powered case triage and real-time 360-degree workflow dashboards for enhanced efficiency and oversight
NovoPath 360 is a comprehensive anatomic pathology laboratory information system (AP LIS) that streamlines workflows from specimen accessioning and grossing to final reporting and distribution. It supports digital pathology integration, synoptic reporting, voice recognition, and AI-driven tools for case management and quality assurance. Designed for scalability, it offers both cloud-based and on-premise deployment options to meet the needs of modern pathology labs.
Pros
- Robust workflow automation tailored for anatomic pathology
- Strong digital pathology and AI integration capabilities
- Flexible deployment and extensive customization options
Cons
- Steep initial learning curve for complex features
- Higher pricing may not suit very small labs
- Some reported challenges with legacy system integrations
Best For
Medium to large pathology labs seeking a scalable AP LIS with advanced digital and AI features.
Pricing
Custom quote-based pricing; typically subscription model starting at $10,000+ annually depending on lab size and modules.
SoftPath Dx
specializedRobust anatomic pathology software featuring voice dictation, synoptic templates, and grossing tools.
Integrated multimedia pathology workstation for capturing and linking gross/micro images directly to reports
SoftPath Dx by SCC Soft Computer is a comprehensive anatomic pathology laboratory information system (AP-LIS) that manages the entire pathology workflow from specimen accessioning and grossing to microscopic review, reporting, and archiving. It supports digital pathology integration, customizable templates, and regulatory compliance tools like CAP and CLIA checklists. Designed for high-volume labs, it enhances efficiency through multimedia capture and advanced case tracking.
Pros
- Robust workflow automation for anatomic pathology processes
- Strong integration with EMRs, scanners, and digital pathology systems
- Customizable synoptic reporting and quality assurance modules
Cons
- Steep learning curve for new users due to extensive customization options
- Pricing can be prohibitive for small labs
- Limited native mobile app functionality
Best For
Mid-sized to large pathology labs handling high case volumes that require enterprise-grade integration and compliance features.
Pricing
Enterprise licensing with custom quotes; typically $40,000–$150,000+ annually depending on modules, users, and deployment.
Psyche PATH
specializedIntegrated pathology information system for accessioning, tracking, and multimedia reporting in labs.
Advanced synoptic reporting engine with built-in CAP checklists and voice-to-text transcription for pathologists
Psyche PATH from Psyche Systems is a specialized Laboratory Information System (LIS) tailored for pathology labs, managing anatomic pathology, cytology, histopathology, molecular testing, and surgical workflows. It offers end-to-end specimen tracking, automated reporting with synoptic templates, integration with EMRs and lab instruments, and compliance tools for CAP, CLIA, and HIPAA standards. The platform supports both cloud and on-premise deployments, focusing on efficiency in high-volume pathology environments.
Pros
- Highly specialized pathology workflows with synoptic reporting and CAP protocol support
- Seamless integrations with EMRs, analyzers, and billing systems
- Reliable customer support and regular updates for compliance
Cons
- Higher pricing tier limits appeal for small labs
- Learning curve for advanced customization features
- Limited native mobile app functionality
Best For
Mid-sized pathology labs needing robust anatomic and molecular pathology management with strong regulatory compliance.
Pricing
Custom quote-based pricing; typically $10,000–$50,000+ annually depending on lab size, modules, and deployment type.
CGM Anatomic Pathology
enterpriseFull-featured AP solution with case management, quality control, and interoperability standards support.
Integrated voice recognition and dictation system that accelerates report generation while maintaining structured data capture.
CGM Anatomic Pathology is a comprehensive anatomic pathology laboratory information system (AP-LIS) designed to manage workflows from specimen accessioning to final reporting in surgical pathology, cytology, and autopsy cases. It supports structured synoptic reporting, multimedia case documentation, and integration with digital pathology scanners and EHRs. The solution emphasizes compliance with CAP and CLIA standards while offering voice recognition for dictation and customizable templates to streamline lab operations.
Pros
- Robust workflow automation across AP disciplines
- Advanced synoptic and multimedia reporting tools
- Strong interoperability with EHRs and scanners
Cons
- Steep learning curve for new users
- Complex customization requires IT support
- Pricing lacks transparency without a quote
Best For
Mid-to-large anatomic pathology labs handling high case volumes that need scalable, compliant workflow management.
Pricing
Enterprise custom pricing via quote; typically subscription-based starting at $40,000-$100,000 annually depending on modules and lab size.
XIFIN LIS
enterpriseLaboratory information system optimized for pathology billing, workflows, and compliance management.
Integrated AI-driven revenue intelligence and denial management for pathology-specific billing optimization
XIFIN LIS is a cloud-based laboratory information system tailored for pathology labs, managing end-to-end workflows including specimen accessioning, case management, anatomic pathology reporting, and molecular testing. It excels in integrating AI-driven tools for image analysis and diagnostics while providing robust revenue cycle management (RCM) to streamline billing and maximize reimbursements. The platform ensures regulatory compliance and scalability for high-volume operations, supporting integration with EMRs and instruments.
Pros
- Comprehensive revenue cycle management with denial prevention
- AI-powered pathology workflows and image analysis
- Scalable cloud platform with strong integrations
Cons
- Steep learning curve for new users
- Custom pricing can be expensive for smaller labs
- Some reporting customizations require vendor support
Best For
Large pathology labs handling complex anatomic and molecular testing with high billing volumes.
Pricing
Quote-based enterprise pricing, typically subscription model starting at $50,000+ annually depending on lab size and volume.
Proscia Concentriq
specializedDigital pathology platform for whole slide imaging, AI analysis, and remote collaboration.
Concentriq AI suite with FDA-cleared and validated algorithms for precise tissue analysis and case prioritization
Proscia Concentriq is a cloud-based digital pathology platform designed for pathology labs to manage whole slide images, streamline workflows, and leverage AI for diagnostics. It offers tools for image viewing, annotation, collaboration, and integration with laboratory information systems (LIS). The platform supports scalable deployment from single sites to enterprise-wide implementations, enhancing efficiency in slide review and reporting.
Pros
- Advanced AI algorithms for automated image analysis and quantification
- Scalable cloud infrastructure with robust collaboration tools
- Seamless integration with scanners, LIS, and EHR systems
Cons
- High enterprise-level pricing limits accessibility for smaller labs
- Steep learning curve for non-digital native users
- Heavy reliance on high-speed internet and quality hardware scanners
Best For
Mid-to-large pathology labs transitioning to digital pathology with a focus on AI-enhanced diagnostics and workflow automation.
Pricing
Custom enterprise pricing via quote; typically subscription-based starting at tens of thousands annually depending on scale and features.
PathAI
general_aiAI-driven pathology assistant for improving diagnostic accuracy and lab efficiency.
AISight's AI-driven whole-slide analysis with patented deep learning models trained on millions of annotated pathology images for superior diagnostic precision.
PathAI is an AI-powered pathology platform that leverages deep learning algorithms to analyze digital pathology slides, assisting pathologists in cancer diagnostics, tumor detection, and prognosis prediction. It integrates into lab workflows via the AISight platform, enabling case prioritization, quality control, and quantifiable insights from whole-slide images. Designed for precision medicine, it supports pharmaceutical research and clinical labs with FDA-cleared tools for specific assays like breast and prostate cancer.
Pros
- Advanced AI algorithms with high accuracy in tumor detection and quantification
- FDA-cleared assays and seamless integration with digital pathology scanners
- Significant workflow efficiency gains through case prioritization and QA tools
Cons
- High implementation costs and custom enterprise pricing
- Requires existing digital pathology infrastructure and scanners
- Limited breadth of AI models beyond key cancers, with a learning curve for full utilization
Best For
Large clinical pathology labs and research institutions seeking AI augmentation for cancer diagnostics and precision pathology workflows.
Pricing
Custom enterprise licensing with subscription models; typically starts at $100K+ annually plus per-slide or per-case fees, depending on volume and modules.
Conclusion
The reviewed pathology lab software each bring unique value, but Sunquest PowerPath emerges as the top choice, boasting comprehensive enterprise workflow automation and synoptic reporting. Epic Beaker and Cerner PathNet follow closely, offering seamless EHR integration and advanced multi-workflow support, respectively, as strong alternatives for varied operational needs.
Explore Sunquest PowerPath to unlock enterprise-level efficiency and precision, tailored to streamline your lab's day-to-day operations.
Tools Reviewed
All tools were independently evaluated for this comparison