Quick Overview
- 1#1: Kareo - Cloud-based medical billing and practice management software that streamlines claims processing and revenue cycle management for small to mid-sized practices.
- 2#2: AdvancedMD - Integrated EHR and practice management platform with advanced billing features including automated claims and denial management.
- 3#3: athenahealth - Cloud-based EHR and revenue cycle management solution offering superior claims scrubbing and payer connectivity for efficient medical billing.
- 4#4: DrChrono - Mobile-first EHR with built-in billing tools for real-time charge capture, superbilling, and claims submission.
- 5#5: NextGen Healthcare - Enterprise practice management and EHR system with robust financial tools for medical billing and analytics.
- 6#6: eClinicalWorks - Comprehensive EHR and practice management software featuring integrated billing, eligibility checks, and ERA posting.
- 7#7: Office Ally - Free medical billing clearinghouse supporting claims submission, tracking, and patient payments compatible with legacy systems like Medical Manager.
- 8#8: Availity - Healthcare clearinghouse providing EDI transactions, claims management, and payer connectivity for Medical Manager users.
- 9#9: Practice Fusion - Free cloud EHR with billing integrations for electronic claims and practice revenue optimization.
- 10#10: CharmHealth - Affordable EHR and practice management tool with built-in medical billing, scheduling, and telehealth features.
We ranked these tools based on performance in key areas—including claims processing efficiency, ease of use, feature depth (such as EHR integration or denial management), and overall value—ensuring each represents a top-tier choice for diverse practice needs.
Comparison Table
Navigating medical practice billing software requires clarity; this comparison table breaks down key tools like Kareo, AdvancedMD, athenahealth, DrChrono, NextGen Healthcare, and more. Readers will gain insights into features, pricing, integration flexibility, and user experience to identify the best fit for their practice's unique needs.
| # | Tool | Category | Overall | Features | Ease of Use | Value |
|---|---|---|---|---|---|---|
| 1 | Kareo Cloud-based medical billing and practice management software that streamlines claims processing and revenue cycle management for small to mid-sized practices. | specialized | 9.4/10 | 9.6/10 | 9.2/10 | 9.0/10 |
| 2 | AdvancedMD Integrated EHR and practice management platform with advanced billing features including automated claims and denial management. | enterprise | 8.9/10 | 9.4/10 | 8.2/10 | 8.0/10 |
| 3 | athenahealth Cloud-based EHR and revenue cycle management solution offering superior claims scrubbing and payer connectivity for efficient medical billing. | enterprise | 8.7/10 | 9.2/10 | 7.8/10 | 8.1/10 |
| 4 | DrChrono Mobile-first EHR with built-in billing tools for real-time charge capture, superbilling, and claims submission. | specialized | 8.7/10 | 9.2/10 | 8.5/10 | 8.0/10 |
| 5 | NextGen Healthcare Enterprise practice management and EHR system with robust financial tools for medical billing and analytics. | enterprise | 8.1/10 | 8.7/10 | 7.4/10 | 7.9/10 |
| 6 | eClinicalWorks Comprehensive EHR and practice management software featuring integrated billing, eligibility checks, and ERA posting. | enterprise | 7.2/10 | 8.1/10 | 6.3/10 | 6.8/10 |
| 7 | Office Ally Free medical billing clearinghouse supporting claims submission, tracking, and patient payments compatible with legacy systems like Medical Manager. | specialized | 7.8/10 | 7.5/10 | 8.2/10 | 9.0/10 |
| 8 | Availity Healthcare clearinghouse providing EDI transactions, claims management, and payer connectivity for Medical Manager users. | enterprise | 8.1/10 | 8.8/10 | 7.6/10 | 7.9/10 |
| 9 | Practice Fusion Free cloud EHR with billing integrations for electronic claims and practice revenue optimization. | specialized | 7.6/10 | 7.2/10 | 8.4/10 | 9.1/10 |
| 10 | CharmHealth Affordable EHR and practice management tool with built-in medical billing, scheduling, and telehealth features. | specialized | 8.1/10 | 8.0/10 | 8.3/10 | 8.5/10 |
Cloud-based medical billing and practice management software that streamlines claims processing and revenue cycle management for small to mid-sized practices.
Integrated EHR and practice management platform with advanced billing features including automated claims and denial management.
Cloud-based EHR and revenue cycle management solution offering superior claims scrubbing and payer connectivity for efficient medical billing.
Mobile-first EHR with built-in billing tools for real-time charge capture, superbilling, and claims submission.
Enterprise practice management and EHR system with robust financial tools for medical billing and analytics.
Comprehensive EHR and practice management software featuring integrated billing, eligibility checks, and ERA posting.
Free medical billing clearinghouse supporting claims submission, tracking, and patient payments compatible with legacy systems like Medical Manager.
Healthcare clearinghouse providing EDI transactions, claims management, and payer connectivity for Medical Manager users.
Free cloud EHR with billing integrations for electronic claims and practice revenue optimization.
Affordable EHR and practice management tool with built-in medical billing, scheduling, and telehealth features.
Kareo
specializedCloud-based medical billing and practice management software that streamlines claims processing and revenue cycle management for small to mid-sized practices.
Kareo Intelligence analytics engine for predictive denial prevention and revenue forecasting
Kareo is a cloud-based medical billing and practice management platform that specializes in revenue cycle management for healthcare providers and billing companies. It automates claims submission to over 4,000 payers, handles eligibility verification, payment posting, and denial management to maximize reimbursements. With integrated analytics and reporting, Kareo helps practices track financial performance and improve cash flow efficiency.
Pros
- High first-pass claims acceptance rate (up to 98%) reducing denials
- Comprehensive automation for AR management and payment posting
- Scalable pricing and strong integrations with major EHRs and PMS systems
Cons
- Higher costs for small practices with low volume
- Steep initial setup for complex workflows
- Customer support response times can vary during peak periods
Best For
Mid-sized medical practices and professional billing companies focused on optimizing revenue cycle efficiency.
Pricing
Starts at $110/provider/month for core billing, plus per-claim fees (e.g., $0.25/claim); enterprise plans custom quoted.
AdvancedMD
enterpriseIntegrated EHR and practice management platform with advanced billing features including automated claims and denial management.
Integrated denial management and predictive analytics that proactively identify and resolve claim issues before submission
AdvancedMD is a comprehensive cloud-based practice management and EHR platform with advanced medical billing features tailored for healthcare providers. It excels in revenue cycle management, including electronic claims submission, automated denial scrubbing, AR tracking, and patient payment processing. The software integrates billing seamlessly with scheduling, clinical documentation, and reporting tools to optimize cash flow and compliance for medical practices.
Pros
- Robust revenue cycle management with high claims acceptance rates and denial prevention tools
- Seamless integration with EHR, scheduling, and patient portal for end-to-end workflow
- Advanced analytics and reporting for billing performance insights
Cons
- Pricing can be expensive for small practices with custom quotes required
- Steep learning curve for advanced billing configurations
- Occasional customer support delays during peak times
Best For
Mid-sized to large medical practices seeking an all-in-one integrated billing and EHR solution with strong RCM capabilities.
Pricing
Custom subscription pricing starting at around $400-$700 per provider/month for billing modules, scaling with practice size and add-ons; quotes required.
athenahealth
enterpriseCloud-based EHR and revenue cycle management solution offering superior claims scrubbing and payer connectivity for efficient medical billing.
AI-driven revenue intelligence that predicts denials and optimizes collections proactively
athenahealth is a cloud-based EHR and practice management platform with robust medical billing capabilities, enabling automated claims processing, eligibility verification, and revenue cycle management. It integrates seamlessly with electronic health records to reduce errors and accelerate reimbursements for medical practices. Designed for scalability, it supports multi-location practices with advanced analytics for financial performance.
Pros
- Comprehensive revenue cycle management with automated claims scrubbing and denial prevention
- Seamless integration with EHR for end-to-end workflow efficiency
- Advanced analytics and reporting for billing insights and forecasting
Cons
- High subscription costs and implementation fees
- Steep learning curve for new users due to feature density
- Limited customization options without additional vendor support
Best For
Mid-sized to large medical practices needing an integrated EHR-billing solution with strong analytics.
Pricing
Custom enterprise pricing typically starts at $400+ per provider per month, plus one-time implementation fees of $10,000+.
DrChrono
specializedMobile-first EHR with built-in billing tools for real-time charge capture, superbilling, and claims submission.
Native iPad/iPhone app for full charting, superbills, and claims submission directly from mobile devices
DrChrono is a cloud-based EHR and practice management platform with integrated medical billing software designed for ambulatory practices. It handles electronic claims submission to major payers, eligibility verification, payment posting, denial management, and revenue cycle analytics all within a unified interface. The system supports mobile access via iOS apps, enabling providers to manage billing tasks remotely while ensuring HIPAA compliance.
Pros
- Seamless EHR-billing integration reduces errors and speeds up workflows
- Mobile iOS app allows billing and claims management on-the-go
- Real-time eligibility checks and automated superbills improve cash flow
Cons
- Pricing can escalate with add-ons and per-claim fees for high-volume practices
- Customer support response times vary, especially for complex billing issues
- Advanced customization for specialty billing rules requires additional setup
Best For
Small to medium-sized ambulatory practices needing an all-in-one mobile-friendly EHR and billing solution.
Pricing
Custom subscription starting at ~$200/provider/month for basic plans, plus ~$0.09/claim and optional clearinghouse fees; enterprise pricing available.
NextGen Healthcare
enterpriseEnterprise practice management and EHR system with robust financial tools for medical billing and analytics.
AI-driven predictive analytics for denial prevention and revenue optimization
NextGen Healthcare's Medical Manager Billing Software, part of their enterprise EHR and practice management suite, provides comprehensive revenue cycle management for medical practices. It automates charge capture, claims scrubbing, electronic submission, denial management, and payment posting to streamline billing workflows. Designed for scalability, it integrates clinical and financial data to improve reimbursement rates and reduce errors.
Pros
- Seamless EHR integration for accurate charge capture
- Advanced denial prevention and automated workflows
- Scalable for multi-location and multi-specialty practices
Cons
- High implementation costs and lengthy setup
- Complex interface with steep learning curve
- Mixed reviews on customer support responsiveness
Best For
Mid-to-large medical practices needing robust, integrated billing within an enterprise EHR system.
Pricing
Quote-based pricing, typically $400-$700 per provider per month, plus significant one-time implementation fees.
eClinicalWorks
enterpriseComprehensive EHR and practice management software featuring integrated billing, eligibility checks, and ERA posting.
Healow Revenue Cycle Management with AI-driven claims optimization and automated denial appeals
eClinicalWorks is a comprehensive EHR and practice management platform with robust billing capabilities, enabling medical practices to manage claims submission, denial management, and revenue cycle processes seamlessly. It integrates billing directly with patient records, scheduling, and reporting tools to streamline workflows for healthcare providers. As a Medical Manager Billing Software solution, it supports electronic claims to major payers, eligibility verification, and AR aging reports, making it suitable for multi-provider practices.
Pros
- Integrated EHR and billing for end-to-end revenue cycle management
- Advanced claims scrubbing and denial management tools
- Strong reporting and analytics for financial performance
Cons
- Steep learning curve and outdated user interface
- High implementation costs and ongoing fees
- Inconsistent customer support and frequent updates causing disruptions
Best For
Large multi-specialty practices or hospitals needing a fully integrated EHR-billing solution with scalability.
Pricing
Custom pricing starting at $449 per provider/month, plus setup fees of $5,000+ and additional costs for training and modules.
Office Ally
specializedFree medical billing clearinghouse supporting claims submission, tracking, and patient payments compatible with legacy systems like Medical Manager.
Free real-time eligibility verification across thousands of payers, saving practices significant time and money on pre-authorizations.
Office Ally is a web-based medical billing clearinghouse that enables healthcare providers to submit claims electronically, perform real-time eligibility checks, and process electronic remittances (ERAs) without needing dedicated software installations. It supports ANSI 5010 standards and offers free core services like eligibility verification and claims scrubbing for most payers. Ideal for streamlining revenue cycle management, it integrates with various EHR and practice management systems to reduce billing errors and accelerate reimbursements.
Pros
- Free eligibility verification and basic claims submission for most payers
- High claims acceptance rates with built-in scrubbing
- No software download required; fully web-based access
Cons
- Limited advanced analytics and reporting compared to full PM suites
- Customer support primarily via email/tickets with variable response times
- Some premium features require pay-per-use fees
Best For
Small to mid-sized medical practices needing a cost-effective clearinghouse for core billing tasks without complex practice management.
Pricing
Free for core eligibility checks and claims submission; pay-per-claim fees start at $0.09 or subscription plans from $19/month for advanced features like ERA auto-posting.
Availity
enterpriseHealthcare clearinghouse providing EDI transactions, claims management, and payer connectivity for Medical Manager users.
Industry-leading payer connectivity hub linking to thousands of payers for seamless, real-time data exchange.
Availity is a robust health information network platform designed for revenue cycle management, enabling healthcare providers to submit claims, verify patient eligibility, track payments, and analyze billing performance. It connects providers to over 3,000 payers, covering more than 90% of insured lives in the US, streamlining administrative workflows and reducing claim denials. As a cloud-based solution, it integrates with various EHR and practice management systems to support efficient medical billing operations for practices of all sizes.
Pros
- Extensive payer network for broad connectivity and fast reimbursements
- Real-time eligibility verification and claims status tracking
- Advanced analytics and denial management tools to optimize revenue
Cons
- Steep learning curve for new users due to complex interface
- Pricing can be costly for small practices with low volume
- Heavy reliance on integrations which may require IT support
Best For
Mid-to-large medical practices and hospitals needing comprehensive payer connectivity and revenue cycle automation.
Pricing
Custom subscription plans with transaction-based fees; typically $200-$1,000+ per month depending on volume and features, often bundled with EHR vendors.
Practice Fusion
specializedFree cloud EHR with billing integrations for electronic claims and practice revenue optimization.
100% free, ad-supported EHR with built-in e-claims submission, eliminating software licensing costs for basic medical billing
Practice Fusion is a cloud-based electronic health record (EHR) platform that includes integrated medical billing tools designed for small to mid-sized practices. It enables users to generate superbills, check insurance eligibility, submit electronic claims to clearinghouses, and track payments directly within the EHR interface. While primarily an EHR solution, its billing module supports revenue cycle management basics like charge capture and denial tracking.
Pros
- Completely free core EHR and basic billing platform reducing upfront costs
- Seamless integration between clinical charting and billing workflows
- Intuitive, web-based interface accessible from any device
Cons
- Limited advanced billing features like full RCM analytics or multi-provider splitting compared to dedicated software
- Transaction fees for claims submission and potential add-on costs for premium features
- Customer support primarily via tickets with occasional delays
Best For
Small independent practices or solo providers needing affordable, integrated EHR and basic billing without complex enterprise requirements.
Pricing
Free for unlimited users and practices; claims processing via integrated clearinghouse with per-claim fees (typically $0.09-$0.25 per transaction) and optional paid upgrades.
CharmHealth
specializedAffordable EHR and practice management tool with built-in medical billing, scheduling, and telehealth features.
Real-time patient eligibility verification integrated directly into the scheduling and billing workflow
CharmHealth is a cloud-based electronic health record (EHR) and practice management platform with integrated medical billing features designed for independent medical practices. It handles revenue cycle management through electronic claims submission to major payers, automated ERA posting, denial management, and patient statement generation. The software combines patient records, scheduling, and billing workflows to minimize errors and accelerate reimbursements, while ensuring HIPAA compliance.
Pros
- Robust billing suite with e-claims, ERA auto-posting, and denial scrubbing
- Intuitive interface accessible via web and mobile
- Responsive customer support and regular updates
Cons
- Advanced reporting and analytics are somewhat limited
- Initial setup and customization require time investment
- Pricing scales up quickly for multi-provider practices
Best For
Small to mid-sized independent medical practices needing an affordable, all-in-one EHR with reliable billing capabilities.
Pricing
Starts at $335 per provider per month (billed annually) for core plans, with premium tiers up to $525+ and one-time implementation fees.
Conclusion
The top 10 tools reviewed offer diverse solutions, from cloud-based efficiency to integrated EHR systems, each addressing unique practice needs. Kareo stands as the clear top choice, streamlining claims processing and revenue cycle management for small to mid-sized practices. AdvancedMD and athenahealth are strong alternatives, with AdvancedMD excelling in integrated EHR and denial management, and athenahealth offering superior claims scrubbing and payer connectivity.
Explore Kareo today to unlock streamlined billing operations and strengthen your practice's financial health.
Tools Reviewed
All tools were independently evaluated for this comparison
