Quick Overview
- 1#1: Epic Beaker - Comprehensive clinical laboratory information system fully integrated with Epic's EHR for seamless order-to-result workflows in hospitals.
- 2#2: Cerner PathNet - Robust laboratory information system embedded in Cerner's health IT suite, managing complex lab operations and diagnostics.
- 3#3: Orchard Harvest - Powerful, scalable LIS optimizing clinical lab processes from accessioning, testing, to reporting and compliance.
- 4#4: Sunquest - Integrated platform for anatomic, clinical, and molecular laboratory management in reference and hospital labs.
- 5#5: SCC SoftLab - Vendor-neutral, high-volume LIS platform with advanced middleware for enterprise lab integration and automation.
- 6#6: MEDITECH Expanse Pathology - Laboratory management solution within MEDITECH's EHR, handling orders, results, and quality control for mid-sized facilities.
- 7#7: Psyche Systems TruLab - Flexible LIS supporting clinical, anatomic, and molecular pathology with customizable workflows and interfaces.
- 8#8: NovoPath - End-to-end anatomic pathology LIS featuring AI-assisted workflows, digital pathology, and case tracking.
- 9#9: LigoLab - Cloud-native pathology platform with AI-driven informatics for streamlined lab operations and outreach.
- 10#10: Xifin LIS - Diagnostics-focused LIS with integrated revenue cycle management for commercial and hospital labs.
We ranked these tools by evaluating key factors: integration strength, workflow scalability, ease of use, AI and automation capabilities, and value, prioritizing those that deliver consistent performance across diverse lab environments.
Comparison Table
Effective medical lab management software streamlines operations, enhances accuracy, and supports data-driven decision-making. This comparison table explores top tools like Epic Beaker, Cerner PathNet, Orchard Harvest, Sunquest, and SCC SoftLab, along with additional options, helping readers identify solutions tailored to their lab’s unique needs—including workflow efficiency and scalability. Discover key features, integration capabilities, and user experience to find the best fit for your facility.
| # | Tool | Category | Overall | Features | Ease of Use | Value |
|---|---|---|---|---|---|---|
| 1 | Epic Beaker Comprehensive clinical laboratory information system fully integrated with Epic's EHR for seamless order-to-result workflows in hospitals. | enterprise | 9.4/10 | 9.8/10 | 7.2/10 | 8.6/10 |
| 2 | Cerner PathNet Robust laboratory information system embedded in Cerner's health IT suite, managing complex lab operations and diagnostics. | enterprise | 9.2/10 | 9.5/10 | 7.8/10 | 8.4/10 |
| 3 | Orchard Harvest Powerful, scalable LIS optimizing clinical lab processes from accessioning, testing, to reporting and compliance. | specialized | 8.7/10 | 9.2/10 | 8.0/10 | 8.4/10 |
| 4 | Sunquest Integrated platform for anatomic, clinical, and molecular laboratory management in reference and hospital labs. | enterprise | 8.7/10 | 9.2/10 | 7.6/10 | 8.1/10 |
| 5 | SCC SoftLab Vendor-neutral, high-volume LIS platform with advanced middleware for enterprise lab integration and automation. | enterprise | 8.4/10 | 9.1/10 | 7.6/10 | 8.0/10 |
| 6 | MEDITECH Expanse Pathology Laboratory management solution within MEDITECH's EHR, handling orders, results, and quality control for mid-sized facilities. | enterprise | 8.4/10 | 9.1/10 | 7.6/10 | 8.0/10 |
| 7 | Psyche Systems TruLab Flexible LIS supporting clinical, anatomic, and molecular pathology with customizable workflows and interfaces. | specialized | 8.1/10 | 8.5/10 | 7.7/10 | 7.9/10 |
| 8 | NovoPath End-to-end anatomic pathology LIS featuring AI-assisted workflows, digital pathology, and case tracking. | specialized | 8.1/10 | 8.7/10 | 7.5/10 | 8.0/10 |
| 9 | LigoLab Cloud-native pathology platform with AI-driven informatics for streamlined lab operations and outreach. | specialized | 8.3/10 | 9.0/10 | 7.5/10 | 8.0/10 |
| 10 | Xifin LIS Diagnostics-focused LIS with integrated revenue cycle management for commercial and hospital labs. | specialized | 7.7/10 | 8.2/10 | 6.9/10 | 7.5/10 |
Comprehensive clinical laboratory information system fully integrated with Epic's EHR for seamless order-to-result workflows in hospitals.
Robust laboratory information system embedded in Cerner's health IT suite, managing complex lab operations and diagnostics.
Powerful, scalable LIS optimizing clinical lab processes from accessioning, testing, to reporting and compliance.
Integrated platform for anatomic, clinical, and molecular laboratory management in reference and hospital labs.
Vendor-neutral, high-volume LIS platform with advanced middleware for enterprise lab integration and automation.
Laboratory management solution within MEDITECH's EHR, handling orders, results, and quality control for mid-sized facilities.
Flexible LIS supporting clinical, anatomic, and molecular pathology with customizable workflows and interfaces.
End-to-end anatomic pathology LIS featuring AI-assisted workflows, digital pathology, and case tracking.
Cloud-native pathology platform with AI-driven informatics for streamlined lab operations and outreach.
Diagnostics-focused LIS with integrated revenue cycle management for commercial and hospital labs.
Epic Beaker
enterpriseComprehensive clinical laboratory information system fully integrated with Epic's EHR for seamless order-to-result workflows in hospitals.
Closed-loop integration with Epic EHR for automated order-to-result workflows with embedded decision support
Epic Beaker is a leading laboratory information system (LIS) from Epic Systems, integrated within the Epic EHR platform, designed to manage end-to-end lab workflows including order management, specimen processing, testing, and result reporting across clinical, anatomic, and molecular labs. It supports high-volume operations in large health systems with advanced automation, rules-based decision support, and compliance tools for regulatory standards like CLIA and CAP. Beaker's strength lies in its seamless interoperability with Epic's broader ecosystem, enabling closed-loop order-result cycles that minimize errors and enhance efficiency.
Pros
- Unparalleled integration with Epic EHR for real-time, bidirectional data flow
- Comprehensive coverage of all lab disciplines with advanced analytics and AI-driven insights
- Robust compliance and quality management tools tailored for high-acuity environments
Cons
- Steep learning curve and lengthy implementation (often 12-24 months)
- High upfront and ongoing costs prohibitive for small to mid-sized labs
- Limited flexibility outside the Epic ecosystem without custom development
Best For
Large hospitals and integrated health systems with Epic EHR seeking enterprise-grade lab management.
Pricing
Custom enterprise licensing, typically $1M+ annually based on bed size and modules, with implementation fees in the multi-millions.
Cerner PathNet
enterpriseRobust laboratory information system embedded in Cerner's health IT suite, managing complex lab operations and diagnostics.
Unified platform integrating all lab disciplines with real-time EHR data synchronization for optimized clinical decision-making
Cerner PathNet is a robust enterprise laboratory information system (LIS) designed to manage end-to-end lab operations, including order management, specimen processing, result reporting, and quality control across disciplines like clinical chemistry, hematology, microbiology, anatomic pathology, and transfusion medicine. Deeply integrated with Cerner's Millennium EHR platform, it facilitates seamless data exchange, reducing errors and improving turnaround times in high-volume environments. PathNet leverages rules engines, workflow automation, and interoperability standards like HL7 and FHIR to support advanced lab analytics and compliance.
Pros
- Seamless integration with Cerner Millennium EHR for unified workflows
- Comprehensive support for multi-discipline labs with advanced automation and rules-based processing
- Strong regulatory compliance tools and scalability for large health systems
Cons
- High implementation costs and lengthy deployment timelines
- Steep learning curve requiring extensive training
- Less ideal for small labs due to complexity and customization challenges
Best For
Large hospitals and integrated health systems needing enterprise-grade, EHR-integrated lab management.
Pricing
Custom enterprise pricing with significant upfront implementation fees (often millions) and ongoing per-user/module subscriptions.
Orchard Harvest
specializedPowerful, scalable LIS optimizing clinical lab processes from accessioning, testing, to reporting and compliance.
Advanced rules-based processing engine for highly customizable, automated lab workflows
Orchard Harvest is a robust Laboratory Information System (LIS) designed for clinical laboratories to manage the full spectrum of lab workflows, from test ordering and specimen collection to result verification and reporting. It excels in automating processes across disciplines like chemistry, hematology, microbiology, and anatomic pathology, with strong support for instrument integration and EMR/HIS connectivity. The system emphasizes regulatory compliance (CLIA, HIPAA) and scalability for high-volume operations.
Pros
- Comprehensive workflow automation and rules engine
- Seamless bi-directional integrations with 1000+ instruments and EHRs
- Strong compliance and quality control tools
Cons
- Steep learning curve and complex initial configuration
- Custom pricing can be expensive for small labs
- Limited native mobile app functionality
Best For
Mid-to-large clinical laboratories handling high-volume testing that require scalable, integration-heavy LIS solutions.
Pricing
Custom quote-based pricing; typically subscription model starting at $10,000+ annually depending on modules, users, and lab size, plus implementation fees.
Sunquest
enterpriseIntegrated platform for anatomic, clinical, and molecular laboratory management in reference and hospital labs.
Specialized Transfusion Medicine module with full blood bank lifecycle management from donor to patient
Sunquest provides a comprehensive Laboratory Information System (LIS) tailored for clinical, anatomic pathology, blood bank, and molecular diagnostics labs. It manages end-to-end workflows including specimen collection, testing, result verification, reporting, and billing, with strong support for regulatory compliance like CAP, CLIA, and HIPAA. The platform excels in high-volume environments through robust instrument integration and customizable rule-based processing.
Pros
- Extensive integration with 300+ analyzers and EHR systems
- Advanced modules for blood bank and anatomic pathology
- Proven scalability for enterprise-level labs
Cons
- Complex implementation and steep learning curve
- Dated user interface compared to modern SaaS LIS
- High upfront costs with custom pricing
Best For
Large hospital systems or reference labs managing high-volume, complex testing workflows.
Pricing
Custom enterprise licensing; annual costs typically $100K+ based on modules, users, and scale.
SCC SoftLab
enterpriseVendor-neutral, high-volume LIS platform with advanced middleware for enterprise lab integration and automation.
Bidirectional middleware for seamless integration with 1,000+ analyzers and instruments
SCC SoftLab is a comprehensive Laboratory Information System (LIS) designed for clinical laboratories, managing the full spectrum of lab operations from test ordering and specimen processing to result reporting and billing. It supports multiple lab disciplines including chemistry, hematology, microbiology, anatomic pathology, blood bank, and molecular diagnostics. The platform offers robust integration with analyzers, EMRs/EHRs, and practice management systems, ensuring seamless data flow and regulatory compliance.
Pros
- Extensive feature set covering all lab workflows and disciplines
- Scalable for small to enterprise-level labs with high-volume throughput
- Strong integrations with over 1,000 instrument interfaces and EMRs
Cons
- Complex implementation and steep learning curve for users
- User interface feels dated compared to modern cloud-native solutions
- Custom pricing lacks transparency and can be costly for smaller labs
Best For
Mid-to-large clinical laboratories needing a highly customizable, integration-heavy LIS for complex, high-volume operations.
Pricing
Custom enterprise pricing via quote; typically $100K+ annually for mid-sized labs, including modules, implementation, and support.
MEDITECH Expanse Pathology
enterpriseLaboratory management solution within MEDITECH's EHR, handling orders, results, and quality control for mid-sized facilities.
Native EHR integration enabling real-time access to clinical history, orders, and results within pathology workflows
MEDITECH Expanse Pathology is an integrated pathology module within the Expanse EHR platform, designed specifically for anatomic pathology workflows in hospital and health system labs. It manages the full lifecycle from specimen accessioning and grossing to microscopic examination, synoptic reporting, and case distribution. The system supports cytology, surgical pathology, and autopsies while ensuring compliance with CAP and other standards through seamless EHR integration.
Pros
- Deep integration with MEDITECH Expanse EHR for unified patient data and workflows
- Advanced synoptic reporting and CAP checklist support for compliance
- Robust image management and voice-enabled dictation for pathologists
Cons
- Steep learning curve due to enterprise-level complexity
- Limited flexibility for non-MEDITECH environments or standalone labs
- High upfront implementation and customization costs
Best For
Large hospitals and integrated health systems using MEDITECH EHR that need a tightly coupled pathology solution.
Pricing
Enterprise licensing model with custom pricing based on facility size and modules; typically bundled in multi-year EHR contracts starting at $500K+ annually for mid-sized implementations.
Psyche Systems TruLab
specializedFlexible LIS supporting clinical, anatomic, and molecular pathology with customizable workflows and interfaces.
Highly configurable rules engine for automated workflows across diverse lab disciplines
Psyche Systems TruLab is a comprehensive web-based Laboratory Information System (LIS) tailored for clinical, anatomic pathology, microbiology, and reference labs. It manages the full lab lifecycle, including specimen accessioning, workflow automation, instrument integration, result verification, and reporting. TruLab ensures regulatory compliance (CLIA, HIPAA) with robust quality control, audit trails, and customizable rules engines.
Pros
- Extensive modular support for multiple lab disciplines (core lab, AP, micro, molecular)
- Strong integration with EHRs, analyzers, and billing systems
- Reliable scalability for mid-sized to large labs with proven uptime
Cons
- Steep learning curve for complex customizations
- Pricing lacks transparency; requires vendor quotes
- Limited mobile accessibility compared to newer cloud-native competitors
Best For
Mid-sized hospitals and reference labs seeking a flexible, enterprise-grade LIS with deep customization options.
Pricing
Custom enterprise pricing starting at $50K+ annually based on modules, lab volume, and implementation; perpetual licenses with maintenance also available—contact for quote.
NovoPath
specializedEnd-to-end anatomic pathology LIS featuring AI-assisted workflows, digital pathology, and case tracking.
Integrated gross pathology workstation with barcode-driven imaging and voice recognition for rapid specimen processing.
NovoPath is a specialized anatomic pathology Laboratory Information System (LIS) that manages end-to-end workflows for pathology labs, from accessioning and grossing to microscopy, reporting, and case distribution. It supports digital slide integration, customizable synoptic reports, and compliance with CAP, CLIA, and HIPAA standards. The platform offers web-based access, mobile capabilities, and seamless EHR/EMR integrations to enhance efficiency in high-volume pathology environments.
Pros
- Highly specialized anatomic pathology workflows with grossing stations and multimedia support
- Strong integrations with EMRs, scanners, and digital pathology systems
- Customizable synoptic reporting and regulatory compliance tools
Cons
- Primarily focused on anatomic pathology, lacking broad clinical lab management
- Steep learning curve due to comprehensive feature set
- Pricing is opaque and requires custom quotes
Best For
Mid-sized anatomic pathology labs needing robust, specialized workflow automation and reporting.
Pricing
Custom enterprise pricing upon request; typically subscription-based starting at $10,000+ annually depending on modules and lab size.
LigoLab
specializedCloud-native pathology platform with AI-driven informatics for streamlined lab operations and outreach.
Unified Orchestrator platform that seamlessly combines LIS and full revenue cycle management
LigoLab is an all-in-one pathology informatics platform that provides a unified Laboratory Information System (LIS), revenue cycle management (RCM), and outreach solutions for anatomic, clinical, and molecular labs. It automates workflows from specimen accessioning to billing, ensuring compliance with healthcare standards like HIPAA and CLIA. The cloud-based system integrates with EMRs and offers analytics for operational efficiency and revenue optimization.
Pros
- Comprehensive integration of LIS, RCM, and outreach in one platform
- Advanced automation and AI-driven workflows for high-volume labs
- Strong compliance tools and EMR integrations
Cons
- Steep learning curve for new users
- Custom pricing can be expensive for small labs
- Limited flexibility in customization for niche workflows
Best For
Mid-sized pathology labs needing an end-to-end solution for workflow automation and revenue management.
Pricing
Custom enterprise pricing based on lab size, modules, and users; typically subscription-based starting around $10,000/month for mid-sized labs—contact for quote.
Xifin LIS
specializedDiagnostics-focused LIS with integrated revenue cycle management for commercial and hospital labs.
Embedded Revenue Performance Management (RPM) that uses AI to maximize claim reimbursements directly within the LIS workflow
Xifin LIS is a cloud-based laboratory information system tailored for diagnostic labs, managing the full spectrum of lab operations from specimen collection and processing to result reporting and billing. It integrates seamlessly with revenue cycle management (RCM) tools, automating workflows for anatomic pathology, molecular diagnostics, and clinical testing. The platform emphasizes compliance, analytics, and interoperability with EMRs and payer systems to enhance efficiency and revenue capture.
Pros
- Strong integration of LIS with revenue cycle management for optimized billing and reimbursements
- Advanced analytics and reporting for lab performance insights
- Scalable cloud architecture supporting high-volume labs
Cons
- Steep learning curve due to complex interface and customization needs
- Higher implementation costs and longer setup time
- Limited flexibility for very small labs
Best For
Mid-to-large diagnostic labs focused on anatomic pathology and molecular testing that require tight LIS-RCM integration.
Pricing
Custom enterprise pricing, typically $50,000+ annually based on lab size, modules, and usage.
Conclusion
The top three tools highlight distinct strengths: Epic Beaker leads with seamless integration into electronic health records, streamlining order-to-result workflows in hospitals. Cerner PathNet excels at managing complex lab operations within its health IT suite, and Orchard Harvest offers scalable, compliant processes from accessioning to reporting. Together, they set the standard for lab management, each catering to unique facility needs.
Don’t miss out on Epic Beaker—the top-ranked choice—for a transformative workflow that integrates seamlessly and boosts efficiency.
Tools Reviewed
All tools were independently evaluated for this comparison