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Top 10 Best Lab Sample Tracking Software of 2026

Compare top lab sample tracking software to streamline workflows—find the best fit for your lab's needs today.

Sarah Mitchell

Sarah Mitchell

Feb 11, 2026

10 tools comparedExpert reviewed
Independent evaluation · Unbiased commentary · Updated regularly
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Lab sample tracking is foundational to modern laboratory operations, enabling accuracy, compliance, and seamless workflow—yet the right software can amplify these benefits exponentially. With a broad array of tools available, selecting the ideal solution requires alignment with specific needs; our top 10 list aggregates industry-leading options, each designed to elevate sample management across diverse environments.

Quick Overview

  1. 1#1: LabWare LIMS - Provides enterprise-grade LIMS for comprehensive sample tracking, management, and compliance across industries.
  2. 2#2: STARLIMS - Delivers configurable LIMS software for efficient sample lifecycle tracking and workflow automation in regulated labs.
  3. 3#3: LabVantage - Offers a flexible, next-generation LIMS platform for end-to-end sample management and lab informatics.
  4. 4#4: Thermo Scientific SampleManager - Enterprise LIMS solution for advanced sample tracking, analytics, and integration in biopharma labs.
  5. 5#5: Benchling - Cloud-native platform for biotech R&D featuring robust sample tracking, inventory, and collaboration tools.
  6. 6#6: Sapio LIMS - Unified LIMS and ELN platform enabling harmonized sample tracking and data management in life sciences.
  7. 7#7: LabLynx - Web-based LIMS for customizable sample accessioning, tracking, and reporting in various lab environments.
  8. 8#8: CloudLIMS - Secure cloud-based LIMS focused on sample tracking, inventory control, and quality assurance.
  9. 9#9: Labguru - All-in-one digital lab platform with integrated sample tracking, ELN, and experiment management.
  10. 10#10: Titian Mosaic - Specialized sample management software for precise tracking of compound libraries and biological samples.

We prioritized tools based on robust functionality (including end-to-end lifecycle management), proven reliability, user-friendliness, and value, ensuring each entry meets the rigorous standards of lab efficiency and regulatory adherence.

Comparison Table

Efficient sample tracking is vital for lab operations, accuracy, and compliance, making selecting the right software a key task. This comparison table evaluates leading tools like LabWare LIMS, STARLIMS, LabVantage, Thermo Scientific SampleManager, Benchling, and others, examining features, usability, and integration to help readers find their ideal solution.

Provides enterprise-grade LIMS for comprehensive sample tracking, management, and compliance across industries.

Features
9.8/10
Ease
7.9/10
Value
8.6/10
2STARLIMS logo8.9/10

Delivers configurable LIMS software for efficient sample lifecycle tracking and workflow automation in regulated labs.

Features
9.5/10
Ease
8.0/10
Value
8.4/10
3LabVantage logo8.7/10

Offers a flexible, next-generation LIMS platform for end-to-end sample management and lab informatics.

Features
9.3/10
Ease
7.4/10
Value
8.1/10

Enterprise LIMS solution for advanced sample tracking, analytics, and integration in biopharma labs.

Features
9.5/10
Ease
7.5/10
Value
8.0/10
5Benchling logo8.4/10

Cloud-native platform for biotech R&D featuring robust sample tracking, inventory, and collaboration tools.

Features
9.1/10
Ease
8.0/10
Value
7.7/10
6Sapio LIMS logo8.7/10

Unified LIMS and ELN platform enabling harmonized sample tracking and data management in life sciences.

Features
9.4/10
Ease
7.8/10
Value
8.2/10
7LabLynx logo8.3/10

Web-based LIMS for customizable sample accessioning, tracking, and reporting in various lab environments.

Features
9.2/10
Ease
7.8/10
Value
8.0/10
8CloudLIMS logo8.1/10

Secure cloud-based LIMS focused on sample tracking, inventory control, and quality assurance.

Features
8.7/10
Ease
7.6/10
Value
7.8/10
9Labguru logo8.2/10

All-in-one digital lab platform with integrated sample tracking, ELN, and experiment management.

Features
8.5/10
Ease
7.7/10
Value
7.9/10

Specialized sample management software for precise tracking of compound libraries and biological samples.

Features
8.5/10
Ease
6.9/10
Value
7.2/10
1
LabWare LIMS logo

LabWare LIMS

enterprise

Provides enterprise-grade LIMS for comprehensive sample tracking, management, and compliance across industries.

Overall Rating9.4/10
Features
9.8/10
Ease of Use
7.9/10
Value
8.6/10
Standout Feature

Advanced configurability engine allowing drag-and-drop workflow customization without programming

LabWare LIMS is a leading enterprise-grade Laboratory Information Management System (LIMS) that excels in lab sample tracking, managing the entire sample lifecycle from accessioning and labeling to storage, testing, and disposal. It provides robust workflow automation, instrument integration, and real-time tracking to ensure chain-of-custody integrity in regulated environments. With extensive configurability, it supports complex lab operations across industries like pharmaceuticals, biotech, environmental testing, and food safety.

Pros

  • Unmatched sample tracking with full lifecycle management and barcode/RFID support
  • Seamless integration with hundreds of lab instruments and ERP systems
  • Highly configurable without coding, plus strong regulatory compliance (21 CFR Part 11, ISO 17025)

Cons

  • Steep learning curve and lengthy implementation (6-12 months typical)
  • High upfront costs and ongoing maintenance fees
  • Overkill for small labs due to enterprise focus

Best For

Enterprise-level labs in regulated industries needing scalable, customizable sample tracking with full compliance.

Pricing

Custom enterprise pricing; perpetual licenses or subscriptions start at $100,000+ including implementation, with annual support ~20% of license cost.

2
STARLIMS logo

STARLIMS

enterprise

Delivers configurable LIMS software for efficient sample lifecycle tracking and workflow automation in regulated labs.

Overall Rating8.9/10
Features
9.5/10
Ease of Use
8.0/10
Value
8.4/10
Standout Feature

Advanced chain-of-custody tracking with RFID/barcode support and automated notifications for real-time sample status updates

STARLIMS is a leading Laboratory Information Management System (LIMS) designed for comprehensive sample tracking and laboratory workflow automation across industries like pharmaceuticals, biotech, clinical, and environmental testing. It manages the entire sample lifecycle from receipt and accessioning to testing, storage, reporting, and disposal, ensuring data integrity and regulatory compliance. The platform supports instrument integration, customizable workflows, and real-time visibility into sample status, making it ideal for high-volume, regulated labs.

Pros

  • Highly configurable workflows tailored to complex lab processes
  • Robust compliance tools including 21 CFR Part 11 audit trails and electronic signatures
  • Seamless integration with lab instruments, ELNs, and ERP systems

Cons

  • Steep learning curve and lengthy implementation for non-experts
  • High upfront costs and ongoing maintenance fees
  • Overly complex for small labs with simple tracking needs

Best For

Enterprise-level laboratories in regulated industries needing scalable, compliant end-to-end sample tracking.

Pricing

Custom enterprise pricing via quote; deployment often starts at $100K+ with annual subscriptions scaling by users and modules.

Visit STARLIMSstarlims.com
3
LabVantage logo

LabVantage

enterprise

Offers a flexible, next-generation LIMS platform for end-to-end sample management and lab informatics.

Overall Rating8.7/10
Features
9.3/10
Ease of Use
7.4/10
Value
8.1/10
Standout Feature

SampleManager's advanced pedigree tracking, which provides unbreakable chain-of-custody and complete sample lineage visualization

LabVantage is a robust Laboratory Information Management System (LIMS) that excels in sample tracking and management for industries like pharmaceuticals, biotech, clinical diagnostics, and environmental testing. It provides end-to-end visibility into the sample lifecycle, including accessioning, labeling with barcodes/RFID, workflow routing, chain-of-custody tracking, storage management, and disposal. The platform supports instrument integration, automated workflows, and regulatory compliance features like 21 CFR Part 11, making it ideal for complex, high-volume lab operations.

Pros

  • Comprehensive sample pedigree and lifecycle tracking with full audit trails
  • Highly customizable workflows and no-code configuration tools
  • Seamless integration with lab instruments and third-party systems

Cons

  • Steep learning curve and complex initial setup for non-expert users
  • High implementation costs and lengthy deployment timelines
  • Pricing lacks transparency, often requiring custom quotes

Best For

Enterprise-level laboratories in regulated industries needing scalable, compliant sample tracking for high-throughput operations.

Pricing

Custom quote-based enterprise pricing; typically starts at $50,000+ annually depending on modules, users, and deployment scale.

Visit LabVantagelabvantage.com
4
Thermo Scientific SampleManager logo

Thermo Scientific SampleManager

enterprise

Enterprise LIMS solution for advanced sample tracking, analytics, and integration in biopharma labs.

Overall Rating8.7/10
Features
9.5/10
Ease of Use
7.5/10
Value
8.0/10
Standout Feature

Seamless native integration with Thermo Fisher chromatography data systems and instruments for automated data flow

Thermo Scientific SampleManager is a comprehensive Laboratory Information Management System (LIMS) designed for end-to-end sample tracking, workflow automation, and data management in regulated laboratory environments. It excels in handling complex sample lifecycles from intake and processing to analysis, storage, and reporting while ensuring compliance with standards like FDA 21 CFR Part 11 and ISO 17025. The platform integrates seamlessly with laboratory instruments and supports customizable workflows for industries such as pharmaceuticals, biotechnology, and clinical research.

Pros

  • Robust sample tracking with full chain-of-custody and audit trails
  • Deep integration with Thermo Fisher instruments and CDS like Chromeleon
  • Advanced compliance and data integrity features for regulated labs

Cons

  • Steep learning curve and extensive training required
  • High upfront implementation and customization costs
  • Overly complex for small or non-regulated labs

Best For

Enterprise-level laboratories in pharmaceuticals, biotech, and clinical settings requiring scalable, compliant sample management.

Pricing

Custom enterprise pricing; typically starts at $50,000+ annually for mid-sized deployments, depending on modules, users, and services.

5
Benchling logo

Benchling

specialized

Cloud-native platform for biotech R&D featuring robust sample tracking, inventory, and collaboration tools.

Overall Rating8.4/10
Features
9.1/10
Ease of Use
8.0/10
Value
7.7/10
Standout Feature

Automated sample pedigree tracking linking physical samples to digital molecular data and experiment histories

Benchling is a cloud-based life sciences R&D platform that excels in lab sample tracking through its robust inventory and sample management modules. It enables precise tracking of samples from registration, storage, and usage across locations, with features like barcode scanning, quantity monitoring, and full audit trails for compliance. Integrated with ELN, registry, and molecular design tools, it supports end-to-end workflows for biotech and pharma teams, reducing manual errors and improving data integrity.

Pros

  • Comprehensive sample lifecycle tracking with parent-child relationships
  • Strong integration with ELN and molecular biology tools
  • Enterprise-grade compliance (e.g., 21 CFR Part 11) and scalability

Cons

  • Steep learning curve for complex customizations
  • Premium pricing limits accessibility for small labs
  • Limited offline functionality relying on cloud access

Best For

Mid-to-large biotech and pharmaceutical labs needing integrated sample tracking within broader R&D platforms.

Pricing

Custom quote-based enterprise pricing; free academic plan available, professional tiers start around $100-200/user/month.

Visit Benchlingbenchling.com
6
Sapio LIMS logo

Sapio LIMS

specialized

Unified LIMS and ELN platform enabling harmonized sample tracking and data management in life sciences.

Overall Rating8.7/10
Features
9.4/10
Ease of Use
7.8/10
Value
8.2/10
Standout Feature

No-code configuration engine with Sapio Accelerators for rapid, domain-specific workflow customization

Sapio LIMS is a highly configurable Laboratory Information Management System (LIMS) tailored for life sciences, biotech, and pharmaceutical labs, specializing in advanced sample tracking, workflow automation, and data management. It provides end-to-end visibility into sample lifecycle, from intake to analysis and reporting, with seamless integration of ELN and instrument data. The platform's no-code customization enables tailored solutions for complex assays and high-throughput environments.

Pros

  • Robust sample genealogy and real-time tracking capabilities
  • No-code/low-code configuration for custom workflows
  • Deep integrations with lab instruments, ELN, and analytics tools

Cons

  • Steep learning curve and lengthy implementation
  • High enterprise-level pricing
  • Overkill for small labs with simple tracking needs

Best For

Mid-to-large biotech, pharma, and research organizations needing scalable, integrated sample management with advanced automation.

Pricing

Custom quote-based pricing for enterprise deployments, typically starting at $50,000+ annually based on scale and modules.

7
LabLynx logo

LabLynx

enterprise

Web-based LIMS for customizable sample accessioning, tracking, and reporting in various lab environments.

Overall Rating8.3/10
Features
9.2/10
Ease of Use
7.8/10
Value
8.0/10
Standout Feature

No-code configurator for building custom workflows, forms, and reports tailored to specific lab processes

LabLynx is a comprehensive Laboratory Information Management System (LIMS) tailored for lab sample tracking, offering end-to-end management from accessioning and labeling to processing, storage, aliquoting, and disposal. It supports automated workflows, real-time tracking, chain-of-custody logging, and integration with lab instruments and ELNs for seamless operations across clinical, research, environmental, and manufacturing labs. The platform emphasizes compliance with standards like FDA 21 CFR Part 11, ISO 17025, and GLP, making it suitable for regulated environments. Its modular design allows customization without extensive coding.

Pros

  • Robust sample lifecycle tracking with barcode/RFID support and audit trails
  • Extensive instrument integrations and customizable workflows
  • Strong regulatory compliance tools including electronic signatures

Cons

  • Steep learning curve for configuration and setup
  • Interface feels somewhat dated compared to newer cloud-native tools
  • Pricing can be prohibitive for small labs without scaling needs

Best For

Mid-sized to enterprise laboratories in regulated industries needing a highly configurable LIMS for complex sample workflows.

Pricing

Quote-based pricing with modular subscriptions; typically starts at $10,000-$20,000 annually for basic setups, scaling with users, modules, and hosting (cloud or on-premise).

Visit LabLynxlablynx.com
8
CloudLIMS logo

CloudLIMS

specialized

Secure cloud-based LIMS focused on sample tracking, inventory control, and quality assurance.

Overall Rating8.1/10
Features
8.7/10
Ease of Use
7.6/10
Value
7.8/10
Standout Feature

No-code configurable workflows that adapt to unique lab processes without developer intervention

CloudLIMS is a cloud-based Laboratory Information Management System (LIMS) designed for efficient sample tracking, management, and workflow automation in laboratories across biotech, clinical, food testing, and environmental sectors. It enables accessioning, processing, storage, and disposal of samples with barcode and RFID support, along with real-time inventory tracking and customizable reporting. The platform ensures regulatory compliance through audit trails, electronic signatures, and integration with instruments and ERP systems.

Pros

  • Robust sample tracking with barcode/RFID and chain-of-custody features
  • Highly configurable workflows without coding for diverse lab needs
  • Strong compliance tools for FDA 21 CFR Part 11, ISO 17025, and GLPs

Cons

  • Steep learning curve for advanced customizations
  • Pricing lacks transparency and can be high for small labs
  • Limited native mobile app functionality compared to competitors

Best For

Mid-sized laboratories in regulated industries requiring scalable, compliant sample tracking and workflow automation.

Pricing

Subscription-based with tiered plans (Basic, Standard, Enterprise); custom quotes starting around $500/month based on users and modules—contact sales for details.

Visit CloudLIMScloudlims.com
9
Labguru logo

Labguru

specialized

All-in-one digital lab platform with integrated sample tracking, ELN, and experiment management.

Overall Rating8.2/10
Features
8.5/10
Ease of Use
7.7/10
Value
7.9/10
Standout Feature

Integrated sample lineage tracking that links samples directly to experiments and protocols for complete reproducibility

Labguru is a cloud-based Electronic Lab Notebook (ELN) and Laboratory Information Management System (LIMS) that provides comprehensive sample tracking capabilities, including barcode and RFID support for lifecycle management from intake to disposal. It enables users to monitor sample locations, quantities, lineage, and associated experiments in real-time, with features for inventory control and protocol linking. The platform supports multi-site collaboration and instrument integrations, making it suitable for research and biotech labs focused on traceability.

Pros

  • Robust sample tracking with full lineage, storage mapping, and barcode/RFID support
  • Seamless integration with ELN for experiment-to-sample linking
  • Strong collaboration tools and mobile access for real-time updates

Cons

  • Steep learning curve due to extensive customization options
  • Pricing lacks transparency and can be high for small labs
  • Sample tracking features are embedded in broader ELN suite, not fully standalone

Best For

Mid-sized biotech and research labs needing integrated ELN and sample management for complex workflows.

Pricing

Custom quote-based pricing, typically starting at $100+ per user per month for professional plans, with enterprise options.

Visit Labgurulabguru.com
10
Titian Mosaic logo

Titian Mosaic

specialized

Specialized sample management software for precise tracking of compound libraries and biological samples.

Overall Rating7.8/10
Features
8.5/10
Ease of Use
6.9/10
Value
7.2/10
Standout Feature

Advanced robotic integration for automated sample picking, reformatting, and cherry-picking in high-throughput environments

Titian Mosaic is a specialized sample management software platform designed for life sciences labs, focusing on tracking, storing, and dispensing biological and chemical samples with high precision. It excels in inventory control, automated order fulfillment, and integration with LIMS, robotics, and ELNs to streamline workflows. The system provides robust audit trails and compliance tools for regulated environments like pharma and biotech.

Pros

  • Powerful integration with lab automation and robotics
  • Comprehensive compliance and audit trail features
  • Scalable for high-volume sample libraries

Cons

  • Steep learning curve and complex initial setup
  • Primarily on-premise deployment limits flexibility
  • High cost for smaller labs

Best For

Large pharmaceutical or biotech labs managing extensive sample inventories with automation needs.

Pricing

Custom enterprise pricing upon request; typically starts at high five-figures annually with implementation fees.

Conclusion

The curated lab sample tracking tools highlight exceptional solutions, with LabWare LIMS leading as the top choice, offering enterprise-grade capabilities, robust compliance, and comprehensive lifecycle management. STARLIMS follows closely with configurable workflows for regulated environments, while LabVantage stands out for its flexible, next-generation platform—each addressing unique needs to ensure efficient, reliable tracking. Together, these tools set a high standard for streamlining lab operations, whether for small research teams or large, multi-industry enterprises.

LabWare LIMS logo
Our Top Pick
LabWare LIMS

To elevate your sample management, start with LabWare LIMS to harness its powerful tracking, management, and compliance tools. For specialized needs, explore STARLIMS or LabVantage—both deliver standout performance to fit distinct lab requirements. Take the next step in efficient lab operations today.