Top 10 Best How Much Is Medical Billing Software of 2026

Kareo is a cloud-based medical billing and practice management software tailored for independent healthcare practices. It automates revenue cycle management, including claims submission, scrubbing, denial prevention, and patient payment collection. The platform integrates EHR, scheduling, and analytics to optimize cash flow and operational efficiency for specialties like behavioral health, therapy, and primary care.

athenahealth offers athenaOne, a comprehensive cloud-based platform that integrates electronic health records (EHR), practice management, and advanced revenue cycle management (RCM) with robust medical billing features. It automates claims processing, denial management, patient eligibility verification, and payment posting to streamline billing workflows and maximize reimbursements. The software leverages AI-driven insights and a nationwide provider network for benchmarking and performance optimization.

AdvancedMD is a cloud-based medical billing and practice management platform that streamlines revenue cycle management, including claims scrubbing, electronic submission, payment posting, and denial management. It integrates with EHR systems for seamless workflow and supports specialty-specific billing codes and rules. The software also offers patient payment portals and robust reporting to improve cash flow and compliance for healthcare providers.

DrChrono is a cloud-based electronic health record (EHR) and practice management platform with integrated medical billing tools designed for ambulatory practices. It streamlines revenue cycle management through features like automated claims scrubbing, electronic submission to over 3,000 payers, denial management, and patient payment portals. The software also supports real-time eligibility verification and ERA auto-posting, making it a comprehensive solution for handling billing alongside clinical workflows. Its mobile-first approach allows billing tasks to be completed via iPad or iPhone apps.

eClinicalWorks is a comprehensive electronic health record (EHR) and practice management platform that includes robust medical billing software capabilities for healthcare providers. It streamlines revenue cycle management through automated claims submission, eligibility verification, denial management, and payment posting. The system supports various specialties and practice sizes, integrating billing seamlessly with patient records and scheduling to improve efficiency and cash flow.

Practice Fusion is a cloud-based electronic health record (EHR) platform that includes integrated medical billing features, enabling practices to generate claims, check eligibility, submit to payers electronically, and post payments. It streamlines billing workflows alongside patient charting, scheduling, and e-prescribing in a single interface. Ideal for small practices, it offers a free core solution with robust connectivity to clearinghouses and payers.

CureMD is a cloud-based electronic health records (EHR) and practice management platform with robust medical billing capabilities designed for healthcare providers of all sizes. It automates claims submission, tracks payments, manages denials, and optimizes revenue cycles through integrated tools like electronic remittance advice (ERA) posting and eligibility verification. The software ensures HIPAA compliance and supports specialty-specific coding for efficient reimbursement processes.

NextGen Healthcare offers a comprehensive electronic health records (EHR) and practice management platform with integrated medical billing software designed for ambulatory care providers. The billing module streamlines claims processing, denial management, eligibility verification, and revenue cycle management (RCM) through automation and analytics. It supports specialties with customizable rules engines and integrates seamlessly with the full EHR suite for efficient workflows.

Greenway Health's Prime SUITE is an integrated electronic health record (EHR) and practice management platform with comprehensive medical billing functionality tailored for ambulatory care providers. It handles electronic claims submission, denial management, patient eligibility verification, and revenue cycle analytics to optimize reimbursements. The software supports multi-specialty practices with customizable workflows and robust reporting tools for financial oversight.

CollaborateMD is a cloud-based medical billing and practice management software tailored for healthcare providers, offering end-to-end revenue cycle management. It automates claims submission to multiple payers, handles denial management, patient eligibility checks, and payment posting with integrated clearinghouse services. The platform also includes scheduling, EHR integration, and customizable reporting to streamline practice workflows.