Quick Overview
- 1#1: Epic Systems - Epic provides a comprehensive electronic health record (EHR) platform for large healthcare organizations with full HIPAA compliance for secure patient data management.
- 2#2: Oracle Health - Oracle Health offers integrated EHR and health IT solutions with robust HIPAA-compliant security features for enterprise-scale healthcare delivery.
- 3#3: athenahealth - athenahealth delivers cloud-based EHR, revenue cycle management, and patient engagement tools fully compliant with HIPAA standards.
- 4#4: Veradigm - Veradigm (formerly Allscripts) provides interoperable EHR and practice management software with HIPAA-compliant data handling for ambulatory care.
- 5#5: eClinicalWorks - eClinicalWorks offers EHR, telehealth, and population health management solutions designed to meet HIPAA compliance requirements.
- 6#6: NextGen Healthcare - NextGen Healthcare provides ambulatory EHR and practice management systems with advanced HIPAA-compliant security and interoperability.
- 7#7: DrChrono - DrChrono is a mobile-first EHR platform with integrated billing and telehealth features ensuring HIPAA compliance for specialty practices.
- 8#8: CharmHealth - CharmHealth delivers affordable, cloud-based EHR and practice management software with built-in HIPAA compliance for small to mid-sized practices.
- 9#9: Practice Fusion - Practice Fusion offers a free, web-based EHR system with HIPAA-compliant features for streamlined clinical documentation and patient care.
- 10#10: Kareo - Kareo provides billing, practice management, and EHR tools with HIPAA compliance optimized for independent practices.
Tools were ranked based on rigorous evaluation of HIPAA compliance depth, feature integrity (including EHR capabilities and interoperability), usability, and overall value, ensuring they meet the unique demands of healthcare providers across all scales.
Comparison Table
Choosing the right HIPAA-compliant software is crucial for protecting patient data; this comparison table breaks down key tools like Epic Systems, Oracle Health, and eClinicalWorks, helping readers understand features, security strengths, and practical use cases to find the ideal fit for their practice's needs.
| # | Tool | Category | Overall | Features | Ease of Use | Value |
|---|---|---|---|---|---|---|
| 1 | Epic Systems Epic provides a comprehensive electronic health record (EHR) platform for large healthcare organizations with full HIPAA compliance for secure patient data management. | enterprise | 9.7/10 | 9.9/10 | 7.8/10 | 8.5/10 |
| 2 | Oracle Health Oracle Health offers integrated EHR and health IT solutions with robust HIPAA-compliant security features for enterprise-scale healthcare delivery. | enterprise | 9.4/10 | 9.7/10 | 8.6/10 | 9.1/10 |
| 3 | athenahealth athenahealth delivers cloud-based EHR, revenue cycle management, and patient engagement tools fully compliant with HIPAA standards. | enterprise | 8.7/10 | 9.2/10 | 7.8/10 | 8.1/10 |
| 4 | Veradigm Veradigm (formerly Allscripts) provides interoperable EHR and practice management software with HIPAA-compliant data handling for ambulatory care. | enterprise | 8.4/10 | 8.7/10 | 7.8/10 | 8.2/10 |
| 5 | eClinicalWorks eClinicalWorks offers EHR, telehealth, and population health management solutions designed to meet HIPAA compliance requirements. | enterprise | 8.5/10 | 9.2/10 | 7.8/10 | 8.0/10 |
| 6 | NextGen Healthcare NextGen Healthcare provides ambulatory EHR and practice management systems with advanced HIPAA-compliant security and interoperability. | enterprise | 8.4/10 | 9.1/10 | 7.6/10 | 8.0/10 |
| 7 | DrChrono DrChrono is a mobile-first EHR platform with integrated billing and telehealth features ensuring HIPAA compliance for specialty practices. | specialized | 8.7/10 | 9.2/10 | 8.5/10 | 8.0/10 |
| 8 | CharmHealth CharmHealth delivers affordable, cloud-based EHR and practice management software with built-in HIPAA compliance for small to mid-sized practices. | specialized | 8.2/10 | 8.5/10 | 7.8/10 | 8.0/10 |
| 9 | Practice Fusion Practice Fusion offers a free, web-based EHR system with HIPAA-compliant features for streamlined clinical documentation and patient care. | specialized | 8.2/10 | 8.0/10 | 9.0/10 | 9.5/10 |
| 10 | Kareo Kareo provides billing, practice management, and EHR tools with HIPAA compliance optimized for independent practices. | specialized | 7.8/10 | 8.2/10 | 7.4/10 | 7.1/10 |
Epic provides a comprehensive electronic health record (EHR) platform for large healthcare organizations with full HIPAA compliance for secure patient data management.
Oracle Health offers integrated EHR and health IT solutions with robust HIPAA-compliant security features for enterprise-scale healthcare delivery.
athenahealth delivers cloud-based EHR, revenue cycle management, and patient engagement tools fully compliant with HIPAA standards.
Veradigm (formerly Allscripts) provides interoperable EHR and practice management software with HIPAA-compliant data handling for ambulatory care.
eClinicalWorks offers EHR, telehealth, and population health management solutions designed to meet HIPAA compliance requirements.
NextGen Healthcare provides ambulatory EHR and practice management systems with advanced HIPAA-compliant security and interoperability.
DrChrono is a mobile-first EHR platform with integrated billing and telehealth features ensuring HIPAA compliance for specialty practices.
CharmHealth delivers affordable, cloud-based EHR and practice management software with built-in HIPAA compliance for small to mid-sized practices.
Practice Fusion offers a free, web-based EHR system with HIPAA-compliant features for streamlined clinical documentation and patient care.
Kareo provides billing, practice management, and EHR tools with HIPAA compliance optimized for independent practices.
Epic Systems
enterpriseEpic provides a comprehensive electronic health record (EHR) platform for large healthcare organizations with full HIPAA compliance for secure patient data management.
Care Everywhere network for real-time, secure data exchange across disparate EHR systems while maintaining HIPAA standards
Epic Systems is a leading electronic health record (EHR) platform designed for large healthcare organizations, offering comprehensive management of patient records, clinical workflows, scheduling, billing, and telehealth. It excels in interoperability, allowing seamless data sharing across providers via networks like Care Everywhere. As a fully HIPAA-compliant solution, Epic prioritizes robust security features including encryption, audit trails, and role-based access controls to protect sensitive patient health information.
Pros
- Unmatched depth of features for enterprise-scale healthcare operations
- Proven HIPAA compliance with advanced security and audit capabilities
- Extensive interoperability ecosystem connecting millions of patients and providers
Cons
- Steep learning curve and lengthy implementation process
- High upfront and ongoing costs
- Customization requires significant IT resources
Best For
Large hospitals, health systems, and academic medical centers seeking a scalable, all-in-one EHR with top-tier HIPAA compliance.
Pricing
Custom enterprise pricing, typically starting in the millions annually based on organization size, modules, and users; no public tiers.
Oracle Health
enterpriseOracle Health offers integrated EHR and health IT solutions with robust HIPAA-compliant security features for enterprise-scale healthcare delivery.
Oracle Cloud Infrastructure's built-in HIPAA-compliant security with AI-powered threat detection and automated compliance auditing
Oracle Health is a comprehensive cloud-based electronic health record (EHR) platform that supports clinical workflows, patient management, revenue cycle operations, and population health analytics for healthcare organizations. Built on Oracle Cloud Infrastructure, it ensures robust HIPAA compliance through advanced encryption, access controls, and audit trails to securely handle protected health information (PHI). The solution integrates AI-driven insights and interoperability standards like FHIR to enhance care delivery and operational efficiency across hospitals and health systems.
Pros
- Enterprise-scale scalability with Oracle Cloud for handling massive patient volumes
- Top-tier HIPAA compliance featuring zero-trust security, data sovereignty, and continuous compliance monitoring
- Advanced AI and analytics for predictive care and operational optimization
Cons
- High implementation costs and complexity best suited for large enterprises
- Steep learning curve due to extensive customization options
- Limited flexibility for small practices without significant IT resources
Best For
Large hospitals, health systems, and academic medical centers needing a scalable, highly secure EHR with advanced analytics.
Pricing
Custom enterprise pricing; typically $1M+ annually depending on modules, users, and implementation scale.
athenahealth
enterpriseathenahealth delivers cloud-based EHR, revenue cycle management, and patient engagement tools fully compliant with HIPAA standards.
AI-driven revenue cycle management that automates claims processing and denial management for optimal financial performance
Athenahealth offers athenaOne, a comprehensive cloud-based EHR platform that integrates electronic health records, revenue cycle management, patient engagement, and care coordination for healthcare providers. It is fully HIPAA compliant with advanced encryption, access controls, and audit trails to safeguard protected health information (PHI). The solution scales from small practices to large enterprises, streamlining clinical, administrative, and financial workflows.
Pros
- Enterprise-grade HIPAA compliance with robust security features like data encryption and role-based access
- Integrated all-in-one platform combining EHR, billing, and patient portal for seamless operations
- Powerful revenue cycle management tools that improve claim reimbursements and reduce denials
Cons
- High pricing can be prohibitive for small practices
- Steep learning curve and interface that feels dated to some users
- Limited customization without additional development costs
Best For
Mid-sized to large medical practices needing a scalable, fully integrated HIPAA-compliant EHR with strong revenue cycle capabilities.
Pricing
Custom quotes based on practice size; typically $140-$450 per provider per month plus one-time implementation fees starting at $10,000+.
Veradigm
enterpriseVeradigm (formerly Allscripts) provides interoperable EHR and practice management software with HIPAA-compliant data handling for ambulatory care.
Veradigm Network for secure, nationwide data exchange and real-world evidence generation
Veradigm offers a comprehensive suite of healthcare IT solutions, including electronic health records (EHR), practice management, revenue cycle management, and patient engagement tools tailored for providers. It ensures HIPAA compliance through features like data encryption, role-based access controls, audit logging, and secure cloud infrastructure. The platform emphasizes interoperability via FHIR standards and connections to the Veradigm Network for real-world data insights and care coordination.
Pros
- Strong HIPAA compliance with advanced security and compliance reporting
- Excellent interoperability and integration with major health systems
- Powerful analytics via Veradigm Network for population health management
Cons
- Steep learning curve for non-technical users
- High implementation costs and time
- Custom pricing can be opaque for smaller practices
Best For
Mid-to-large healthcare practices and hospitals needing scalable, interoperable EHR with robust HIPAA safeguards.
Pricing
Custom enterprise pricing; typically $400-$800 per provider/month depending on modules and scale, with implementation fees.
eClinicalWorks
enterpriseeClinicalWorks offers EHR, telehealth, and population health management solutions designed to meet HIPAA compliance requirements.
Healow patient engagement ecosystem for secure, HIPAA-compliant patient communication and self-service portals
eClinicalWorks is a comprehensive electronic health records (EHR) and practice management software platform designed for healthcare providers, offering tools for patient scheduling, billing, telehealth, and electronic prescribing. It ensures HIPAA compliance through robust security features like encrypted data storage, audit trails, and role-based access controls to protect sensitive patient information. The system supports various medical specialties and scales from small practices to large enterprises, with strong interoperability via standards like HL7 and FHIR.
Pros
- Extensive HIPAA-compliant security and compliance tools
- Comprehensive integration with telehealth, billing, and patient portals
- Scalable for practices of all sizes with strong interoperability
Cons
- Steep learning curve and complex interface
- High implementation and customization costs
- Mixed reports on customer support responsiveness
Best For
Medium to large healthcare practices needing a scalable, feature-rich EHR with top-tier HIPAA compliance.
Pricing
Quote-based pricing starting at around $449 per provider per month, scaling with practice size and modules.
NextGen Healthcare
enterpriseNextGen Healthcare provides ambulatory EHR and practice management systems with advanced HIPAA-compliant security and interoperability.
Integrated Population Health Management with predictive analytics for proactive patient care
NextGen Healthcare provides a comprehensive, cloud-based electronic health records (EHR) and practice management platform designed specifically for ambulatory and specialty practices. As a HIPAA-compliant and ONC-certified solution, it ensures secure data handling, interoperability via standards like FHIR, and seamless integration with revenue cycle management. Key capabilities include patient portals, telehealth, population health analytics, and customizable workflows to streamline clinical and administrative tasks.
Pros
- Strong HIPAA compliance with advanced security and audit features
- Extensive interoperability and integration capabilities for seamless data exchange
- Robust analytics and population health management tools
Cons
- Steep learning curve due to complex interface
- High implementation and customization costs
- Customer support response times can be inconsistent
Best For
Mid-sized ambulatory and specialty practices needing scalable EHR with deep revenue cycle integration.
Pricing
Quote-based pricing, typically $300-$600 per provider/month depending on practice size, modules, and implementation.
DrChrono
specializedDrChrono is a mobile-first EHR platform with integrated billing and telehealth features ensuring HIPAA compliance for specialty practices.
Native iOS apps for full EHR charting and management directly from iPad/iPhone
DrChrono is a cloud-based electronic health record (EHR) and practice management (PM) software tailored for medical practices, offering scheduling, billing, telehealth, e-prescribing, and patient engagement tools. It ensures full HIPAA compliance with robust security features like encryption, audit logs, and Business Associate Agreements (BAAs). The platform stands out for its mobile-first design, enabling providers to access patient charts and manage workflows from iOS devices seamlessly.
Pros
- Comprehensive all-in-one EHR/PM with strong telehealth integration
- Excellent mobile app for iOS devices enabling on-the-go charting
- Proven HIPAA compliance with advanced security and audit capabilities
Cons
- Pricing can escalate quickly for small practices with add-ons
- Customization options require technical setup and learning curve
- Fewer third-party integrations than some enterprise competitors
Best For
Small to mid-sized medical practices needing a mobile-friendly, HIPAA-secure EHR with built-in practice management.
Pricing
Custom subscription pricing starts at ~$199/provider/month; scales with users, features like telehealth (~$50+/month extra), and practice size.
CharmHealth
specializedCharmHealth delivers affordable, cloud-based EHR and practice management software with built-in HIPAA compliance for small to mid-sized practices.
CharmTalk AI-powered voice documentation for hands-free charting
CharmHealth is a cloud-based Electronic Health Record (EHR) platform designed for medical practices, offering HIPAA-compliant tools for patient management, scheduling, charting, and billing. It supports telehealth, e-prescribing, and customizable templates to streamline clinical workflows while ensuring data security and compliance. The software integrates practice management and revenue cycle features, making it suitable for primary care and specialty practices.
Pros
- Robust HIPAA compliance with end-to-end encryption and audit trails
- Comprehensive all-in-one suite including EHR, billing, and telehealth
- Customizable charting templates and voice-to-text transcription
Cons
- Steep learning curve for new users due to extensive customization options
- Customer support response times can be inconsistent
- Limited advanced analytics compared to enterprise-level competitors
Best For
Small to medium-sized medical practices looking for an affordable, integrated HIPAA-compliant EHR with telehealth capabilities.
Pricing
Starts at $299 per provider/month for core EHR features, with tiered plans up to $599+ for advanced modules; additional per-user fees apply.
Practice Fusion
specializedPractice Fusion offers a free, web-based EHR system with HIPAA-compliant features for streamlined clinical documentation and patient care.
Free, fully-featured cloud-based EHR with built-in Surescripts e-prescribing certification
Practice Fusion is a cloud-based electronic health record (EHR) platform designed for ambulatory practices, providing tools for charting, e-prescribing, scheduling, billing, and patient engagement. It is fully HIPAA compliant and ONC-certified, ensuring secure handling of protected health information (PHI) with features like audit logs, encryption, and role-based access controls. The software emphasizes simplicity and accessibility, making it suitable for primary care providers transitioning to digital records.
Pros
- Completely free core EHR functionality with no subscription fees
- Intuitive interface that's quick to learn for non-tech-savvy users
- Robust e-prescribing and patient portal integrated seamlessly
Cons
- Limited customization and advanced analytics compared to premium competitors
- Occasional platform ads from pharmaceutical partners
- Customer support response times can be inconsistent
Best For
Small to medium-sized primary care practices seeking a cost-free, user-friendly HIPAA-compliant EHR without complex setup.
Pricing
Free for all core features; revenue generated through non-intrusive pharma ads and optional premium add-ons.
Kareo
specializedKareo provides billing, practice management, and EHR tools with HIPAA compliance optimized for independent practices.
Intelligent claims scrubbing and revenue intelligence that minimizes denials and accelerates reimbursements
Kareo is a cloud-based platform tailored for independent medical practices, providing integrated electronic health records (EHR), practice management, medical billing, and patient engagement tools. It maintains strict HIPAA compliance through features like end-to-end encryption, role-based access controls, audit logs, and secure data centers. The software focuses on streamlining revenue cycle management and administrative workflows to help practices operate efficiently while safeguarding patient data.
Pros
- Robust HIPAA-compliant security with encryption and audit trails
- Excellent revenue cycle management for faster payments and fewer denials
- Integrated telehealth and patient portal for better engagement
Cons
- Steep pricing that may strain small practices
- Interface can feel cluttered with a moderate learning curve
- Customer support response times vary
Best For
Small to mid-sized independent practices seeking reliable billing and EHR with strong HIPAA protections.
Pricing
Starts at around $140 per provider/month for core EHR and billing, with custom quotes for add-ons and scaling tiers.
Conclusion
The review of top HIPAA-compliant software underscores Epic Systems as the leading choice, providing comprehensive tools for secure data management across large organizations. Oracle Health and athenahealth stand out as strong alternatives, each offering tailored features to suit enterprise and diverse practice needs. Together, these solutions highlight the breadth of reliable, compliant healthcare technology available.
To experience industry-leading HIPAA compliance and elevate your practice, start with Epic Systems—its robust features make it the top pick for secure, efficient healthcare operations.
Tools Reviewed
All tools were independently evaluated for this comparison
