Quick Overview
- 1#1: Epic Systems - Comprehensive enterprise EHR platform designed for large hospitals and health systems with advanced interoperability and patient engagement features.
- 2#2: Oracle Health - Integrated EHR and health IT solutions formerly Cerner, offering robust clinical workflows and analytics for diverse healthcare providers.
- 3#3: athenahealth - Cloud-based EHR and revenue cycle management platform that streamlines practice operations and ensures HIPAA compliance for ambulatory care.
- 4#4: eClinicalWorks - All-in-one EHR system with telehealth, patient portal, and population health tools tailored for small to mid-sized practices.
- 5#5: Veradigm - EHR and practice management software formerly Allscripts, focusing on interoperability and data analytics for ambulatory and post-acute care.
- 6#6: NextGen Healthcare - Specialty-focused EHR with AI-driven insights and revenue management for outpatient practices and health systems.
- 7#7: MEDITECH - Patient-centric EHR platform providing scalable solutions for acute and ambulatory care with strong security features.
- 8#8: Greenway Health - Modular EHR system with practice management and interoperability capabilities for primary care and specialty practices.
- 9#9: DrChrono - iPad-native EHR and medical billing software optimized for mobile workflows and small practices.
- 10#10: Kareo - Cloud-based platform combining EHR, billing, and telehealth for independent practices seeking affordability and ease of use.
We ranked these tools based on security robustness, interoperability, user experience, and tailored functionality—from specialized features for small practices to scalable solutions for large health systems—ensuring alignment with diverse clinical and administrative demands.
Comparison Table
Selecting HIPAA compliant EMR software requires careful evaluation, and this comparison table compares tools like Epic Systems, Oracle Health, athenahealth, eClinicalWorks, Veradigm, and more. It outlines key features, usability aspects, and compliance details to help readers understand each software’s fit. By compiling practical insights, the table equips users to identify options that align with their practice’s specific needs.
| # | Tool | Category | Overall | Features | Ease of Use | Value |
|---|---|---|---|---|---|---|
| 1 | Epic Systems Comprehensive enterprise EHR platform designed for large hospitals and health systems with advanced interoperability and patient engagement features. | enterprise | 9.6/10 | 9.8/10 | 7.8/10 | 8.9/10 |
| 2 | Oracle Health Integrated EHR and health IT solutions formerly Cerner, offering robust clinical workflows and analytics for diverse healthcare providers. | enterprise | 9.2/10 | 9.6/10 | 7.8/10 | 8.5/10 |
| 3 | athenahealth Cloud-based EHR and revenue cycle management platform that streamlines practice operations and ensures HIPAA compliance for ambulatory care. | enterprise | 9.1/10 | 9.5/10 | 8.7/10 | 8.2/10 |
| 4 | eClinicalWorks All-in-one EHR system with telehealth, patient portal, and population health tools tailored for small to mid-sized practices. | enterprise | 8.4/10 | 9.1/10 | 7.6/10 | 8.0/10 |
| 5 | Veradigm EHR and practice management software formerly Allscripts, focusing on interoperability and data analytics for ambulatory and post-acute care. | enterprise | 8.4/10 | 9.0/10 | 7.8/10 | 8.0/10 |
| 6 | NextGen Healthcare Specialty-focused EHR with AI-driven insights and revenue management for outpatient practices and health systems. | enterprise | 8.4/10 | 9.2/10 | 7.6/10 | 8.0/10 |
| 7 | MEDITECH Patient-centric EHR platform providing scalable solutions for acute and ambulatory care with strong security features. | enterprise | 8.1/10 | 8.8/10 | 7.2/10 | 7.5/10 |
| 8 | Greenway Health Modular EHR system with practice management and interoperability capabilities for primary care and specialty practices. | enterprise | 8.4/10 | 8.7/10 | 7.8/10 | 8.2/10 |
| 9 | DrChrono iPad-native EHR and medical billing software optimized for mobile workflows and small practices. | enterprise | 8.4/10 | 8.6/10 | 9.1/10 | 7.9/10 |
| 10 | Kareo Cloud-based platform combining EHR, billing, and telehealth for independent practices seeking affordability and ease of use. | enterprise | 8.1/10 | 8.4/10 | 8.7/10 | 7.6/10 |
Comprehensive enterprise EHR platform designed for large hospitals and health systems with advanced interoperability and patient engagement features.
Integrated EHR and health IT solutions formerly Cerner, offering robust clinical workflows and analytics for diverse healthcare providers.
Cloud-based EHR and revenue cycle management platform that streamlines practice operations and ensures HIPAA compliance for ambulatory care.
All-in-one EHR system with telehealth, patient portal, and population health tools tailored for small to mid-sized practices.
EHR and practice management software formerly Allscripts, focusing on interoperability and data analytics for ambulatory and post-acute care.
Specialty-focused EHR with AI-driven insights and revenue management for outpatient practices and health systems.
Patient-centric EHR platform providing scalable solutions for acute and ambulatory care with strong security features.
Modular EHR system with practice management and interoperability capabilities for primary care and specialty practices.
iPad-native EHR and medical billing software optimized for mobile workflows and small practices.
Cloud-based platform combining EHR, billing, and telehealth for independent practices seeking affordability and ease of use.
Epic Systems
enterpriseComprehensive enterprise EHR platform designed for large hospitals and health systems with advanced interoperability and patient engagement features.
Care Everywhere interoperability network, enabling secure real-time data sharing across disparate EHR systems for over 255 million patients.
Epic Systems offers a comprehensive electronic health record (EHR) platform tailored for large-scale healthcare organizations, managing everything from patient records and clinical workflows to billing, scheduling, and population health analytics. Fully HIPAA compliant, it ensures secure handling of protected health information with robust encryption, access controls, and audit trails. Its modular design allows customization across specialties, supporting seamless interoperability through standards like FHIR and its proprietary Care Everywhere network.
Pros
- Unmatched scalability and customization for enterprise-level deployments
- Superior interoperability via Care Everywhere, connecting millions of patients across providers
- Advanced analytics and AI-driven tools like Cosmos for research and predictive insights
Cons
- Steep learning curve and extensive training required for users
- High upfront implementation costs and long deployment timelines
- Less suitable for small practices due to complexity and expense
Best For
Large hospitals, health systems, and academic medical centers requiring a robust, scalable HIPAA-compliant EMR for complex, high-volume operations.
Pricing
Custom enterprise pricing, typically starting at millions for implementation and licensing, with ongoing subscription fees based on users and modules (no public pricing tiers).
Oracle Health
enterpriseIntegrated EHR and health IT solutions formerly Cerner, offering robust clinical workflows and analytics for diverse healthcare providers.
AI-powered Oracle Clinical Digital Assistant for real-time, voice-enabled clinical guidance and workflow automation
Oracle Health, formerly Cerner, is a comprehensive enterprise-grade electronic medical records (EMR) platform tailored for large healthcare organizations, providing integrated solutions for clinical workflows, revenue cycle management, population health, and operational efficiency. It leverages Oracle's cloud infrastructure, AI, and advanced analytics to deliver real-time insights and interoperability standards like FHIR. Fully HIPAA compliant, it prioritizes data security, scalability, and seamless integration across multi-facility health systems.
Pros
- Enterprise-scale scalability and reliability for large health systems
- Advanced AI-driven analytics and clinical decision support
- Robust interoperability and FHIR compliance for seamless data exchange
Cons
- Complex implementation process with long timelines
- Steep learning curve for end-users
- High costs prohibitive for small practices
Best For
Large hospitals, health systems, and IDNs needing a scalable, AI-enhanced EMR with deep integrations.
Pricing
Custom enterprise pricing via quote, typically subscription-based with multi-year contracts starting at millions annually for large deployments.
athenahealth
enterpriseCloud-based EHR and revenue cycle management platform that streamlines practice operations and ensures HIPAA compliance for ambulatory care.
athenahealth Network for population-level benchmarking and predictive revenue intelligence
athenahealth's athenaOne is a comprehensive cloud-based EMR platform designed for ambulatory practices, integrating electronic health records, revenue cycle management, and patient engagement tools. It ensures full HIPAA compliance through robust encryption, access controls, and audit trails, while leveraging a vast interoperability network for seamless data exchange. The system excels in automating clinical workflows, billing, and analytics to improve practice efficiency and financial performance.
Pros
- Strong HIPAA compliance with enterprise-grade security and regular audits
- Integrated revenue cycle management that boosts collections
- Extensive interoperability via the athenahealth network for real-time data insights
Cons
- High subscription costs that may strain smaller practices
- Steep learning curve for advanced features
- Limited customization options compared to some competitors
Best For
Mid-sized ambulatory and specialty practices needing an integrated EMR with strong billing and analytics capabilities.
Pricing
Custom subscription pricing based on provider count and practice revenue, typically $300-$600 per provider per month with implementation fees.
eClinicalWorks
enterpriseAll-in-one EHR system with telehealth, patient portal, and population health tools tailored for small to mid-sized practices.
Healow patient engagement ecosystem with open-access portal, mobile app, and automated messaging for seamless patient-provider communication
eClinicalWorks is a comprehensive, cloud-based electronic health record (EHR) and practice management platform designed for healthcare providers of all sizes. It delivers HIPAA-compliant tools for electronic medical records, patient engagement, telehealth, billing, and interoperability with standards like FHIR and HL7. The software supports specialties from primary care to behavioral health, emphasizing workflow automation and population health management.
Pros
- Robust feature set including EHR, practice management, and telehealth integration
- Strong HIPAA compliance with advanced security and audit trails
- Excellent interoperability and support for meaningful use requirements
Cons
- Steep learning curve and occasionally clunky user interface
- Customer support response times can be inconsistent
- Customization may require additional fees and time
Best For
Mid-sized to large multi-specialty practices needing a scalable, all-in-one HIPAA-compliant EMR with strong interoperability.
Pricing
Custom pricing starting at around $449 per provider per month, plus setup fees and add-ons for telehealth or advanced modules; volume discounts available.
Veradigm
enterpriseEHR and practice management software formerly Allscripts, focusing on interoperability and data analytics for ambulatory and post-acute care.
Veradigm Clinical Data Network, aggregating data from millions of patients for real-world evidence and predictive analytics
Veradigm provides a comprehensive, cloud-based EHR/EMR platform tailored for healthcare providers, offering tools for clinical documentation, e-prescribing, billing, and patient engagement. Fully HIPAA compliant, it emphasizes secure data handling, interoperability via FHIR standards, and integration with labs, pharmacies, and payers. The solution leverages Veradigm's vast data network for advanced analytics, population health management, and revenue cycle optimization.
Pros
- Extensive interoperability and FHIR support for seamless data exchange
- Powerful analytics via the Veradigm Network for population health insights
- Scalable for enterprise-level practices with robust customization
Cons
- Steep learning curve for new users due to complex interface
- Custom pricing can be expensive for smaller practices
- Occasional reports of slow support response times
Best For
Mid-to-large medical practices and health systems needing advanced data analytics and interoperability in a HIPAA-compliant EMR.
Pricing
Custom quote-based pricing, typically $400-$800 per provider per month depending on modules and practice size.
NextGen Healthcare
enterpriseSpecialty-focused EHR with AI-driven insights and revenue management for outpatient practices and health systems.
Enterprise-wide population health management with predictive risk stratification and quality reporting
NextGen Healthcare is a leading EHR and practice management software platform tailored for ambulatory and specialty practices, offering comprehensive tools for clinical documentation, billing, and patient engagement while maintaining full HIPAA compliance. It supports seamless interoperability through standards like FHIR and HL7, enabling data exchange across health systems. The solution includes advanced population health analytics, revenue cycle management, and telehealth capabilities to streamline workflows and improve care delivery.
Pros
- Robust interoperability and data exchange capabilities
- Strong revenue cycle and billing automation
- Advanced population health analytics and reporting
Cons
- Steep learning curve and complex interface
- High upfront implementation costs
- Less intuitive for smaller practices
Best For
Medium to large ambulatory and specialty practices requiring integrated EHR, billing, and population health management.
Pricing
Custom quote-based pricing; typically $600-$1,200 per provider per month, plus implementation fees.
MEDITECH
enterprisePatient-centric EHR platform providing scalable solutions for acute and ambulatory care with strong security features.
Expanse platform's AI-driven predictive analytics for clinical decision support and operational efficiency
MEDITECH offers enterprise-grade Electronic Medical Record (EMR) software, primarily through its Expanse platform, designed for hospitals, health systems, and acute care facilities. It provides comprehensive clinical documentation, order management, revenue cycle tools, and patient engagement features, all while maintaining full HIPAA compliance with robust security measures like encryption and audit logging. The system emphasizes interoperability via standards like FHIR and HL7, supporting seamless data exchange across healthcare ecosystems.
Pros
- Comprehensive suite for acute care and inpatient workflows
- Strong interoperability and data analytics capabilities
- Proven HIPAA compliance with enterprise-level security
Cons
- Steep learning curve and dated user interface in some modules
- High implementation costs and long deployment timelines
- Limited flexibility for small practices or outpatient focus
Best For
Mid-to-large hospitals and integrated health systems needing a scalable, inpatient-centric EMR solution.
Pricing
Custom enterprise pricing with implementation costs often exceeding $1M+, plus annual subscriptions based on beds/users.
Greenway Health
enterpriseModular EHR system with practice management and interoperability capabilities for primary care and specialty practices.
Greenway Marketplace for seamless app integrations and interoperability
Greenway Health offers Prime Suite, a comprehensive EHR/EMR platform tailored for ambulatory and specialty practices, including electronic health records, practice management, revenue cycle management, and patient engagement tools. Fully HIPAA compliant, it supports Meaningful Use certification, interoperability with health information exchanges, and specialty-specific workflows for fields like cardiology and orthopedics. The solution emphasizes secure data handling and automation to streamline clinical and administrative tasks.
Pros
- Robust interoperability with HIEs and third-party apps via Greenway Marketplace
- Specialty-specific templates and customizable workflows
- Strong revenue cycle management with built-in analytics
Cons
- Steep learning curve for new users
- Higher pricing for full suite implementation
- Occasional reports of interface sluggishness
Best For
Mid-sized ambulatory and specialty practices needing scalable EMR with advanced billing and interoperability.
Pricing
Subscription-based, starting at $350-$500 per provider/month, plus implementation fees and add-on modules.
DrChrono
enterpriseiPad-native EHR and medical billing software optimized for mobile workflows and small practices.
Native iPad charting app with Apple Pencil support for efficient bedside documentation
DrChrono is a cloud-based EHR and practice management platform tailored for ambulatory care, offering tools for charting, scheduling, billing, e-prescribing, and telehealth. It supports multi-device access with a strong emphasis on mobile usability, particularly on iOS devices, and is fully HIPAA compliant to ensure secure patient data handling. The software integrates with labs, pharmacies, and payment processors to streamline workflows in medical practices.
Pros
- Highly intuitive mobile app optimized for iPad and iPhone
- Comprehensive revenue cycle management with integrated billing
- Seamless telehealth and patient portal features
Cons
- Limited customization for complex workflows
- Customer support response times can vary
- Pricing scales quickly with additional users and features
Best For
Small to mid-sized ambulatory practices seeking a mobile-first, user-friendly HIPAA-compliant EMR with strong iOS integration.
Pricing
Starts at $199 per provider/month for basic plans, up to $439+ for premium features; custom enterprise pricing available.
Kareo
enterpriseCloud-based platform combining EHR, billing, and telehealth for independent practices seeking affordability and ease of use.
Intelligent Revenue Cycle Management that automates billing, denial management, and reimbursements to optimize cash flow
Kareo is a cloud-based, HIPAA-compliant EMR and practice management platform designed for independent medical practices, offering integrated electronic health records, billing, scheduling, and patient engagement tools. It streamlines clinical workflows, automates revenue cycle management, and provides secure access to patient data via a patient portal and mobile app. The software emphasizes ease of use and scalability for small to mid-sized practices.
Pros
- Seamless integration of EMR, billing, and practice management in one platform
- Intuitive interface with mobile accessibility and patient portal
- Strong automation for revenue cycle management and claims processing
Cons
- Pricing can become expensive with add-ons and per-provider fees
- Customer support response times can be inconsistent
- Limited customization options for advanced clinical workflows
Best For
Small to medium-sized independent medical practices needing an all-in-one HIPAA-compliant solution for EMR and revenue cycle management.
Pricing
Starts at $140-$300 per provider per month depending on the plan (Clinical, Billing, or Complete), with additional transaction fees for claims processing.
Conclusion
Among the reviewed platforms, Epic Systems stands as the top choice, boasting enterprise-level capabilities, advanced interoperability, and robust patient engagement tools. Oracle Health and athenahealth round out the top three, with Oracle excelling in diverse provider workflows and analytics, and athenahealth leading in streamlined ambulatory care compliance. Each tool offers distinct strengths, ensuring a tailored solution for various practice needs.
Begin optimizing your practice’s efficiency and security by exploring Epic Systems—its comprehensive EHR platform is designed to support seamless, compliant care management at every scale.
Tools Reviewed
All tools were independently evaluated for this comparison