Top 10 Best Healthcare Document Management Software of 2026

OnBase by Hyland is a comprehensive enterprise content services platform tailored for healthcare document management, enabling the capture, storage, retrieval, and automation of patient records, forms, and administrative documents. It ensures HIPAA compliance, supports secure sharing across departments, and integrates seamlessly with major EHR systems like Epic and Cerner. With advanced workflow tools and AI-driven processing, it streamlines operations from patient intake to revenue cycle management, reducing errors and improving efficiency in large-scale healthcare environments.

OpenText Documentum is a robust enterprise content management (ECM) platform tailored for healthcare, enabling secure storage, versioning, and lifecycle management of sensitive documents like patient records, clinical trials data, and regulatory submissions. It excels in compliance with standards such as HIPAA, FDA 21 CFR Part 11, and GxP, featuring audit trails, electronic signatures, and role-based access controls. The system supports workflow automation, advanced search with AI-driven capabilities, and integration with healthcare systems like EHRs.

IBM FileNet is a robust enterprise content management (ECM) platform designed for secure storage, management, and retrieval of healthcare documents at scale. It supports document capture, versioning, workflow automation, and advanced search capabilities while ensuring compliance with HIPAA and other regulations through audit trails and access controls. Ideal for handling high-volume patient records, imaging, and administrative documents in complex healthcare environments.

Laserfiche is a robust enterprise content management (ECM) platform tailored for healthcare, enabling secure storage, retrieval, and management of patient records, forms, and administrative documents. It excels in automating workflows for tasks like prior authorizations, billing, and compliance reporting while integrating with EHR systems via standards like HL7 and FHIR. With strong audit trails and role-based access, it ensures HIPAA and other regulatory compliance for healthcare organizations.

DocuWare is a robust cloud-based document management system designed for digitizing, archiving, and automating workflows around business documents. In healthcare, it excels at securely managing patient records, invoices, consent forms, and compliance documentation with features like audit trails, role-based access, and integration with EHR systems. It supports HIPAA compliance through encrypted storage and automated retention policies, enabling efficient retrieval and collaboration across healthcare teams.

M-Files is an intelligent document management platform that uses metadata-driven organization instead of traditional folder structures, ideal for handling complex healthcare documents like patient records and compliance files. It provides HIPAA-compliant security, automated workflows, version control, and AI-powered search to streamline information management in healthcare settings. The system integrates with Microsoft 365 and offers robust auditing and access controls to ensure regulatory adherence.

Kofax offers intelligent document processing (IDP) solutions tailored for healthcare, automating the capture, classification, validation, and extraction of data from patient records, insurance claims, consent forms, and other medical documents. It leverages AI, OCR, and machine learning to streamline workflows while ensuring HIPAA and GDPR compliance. The platform integrates seamlessly with EHR/EMR systems like Epic and Cerner, reducing manual data entry and improving operational efficiency in high-volume environments.

Box (box.com) is a cloud-based content collaboration and document management platform designed for secure storage, sharing, and workflow automation of files, with dedicated HIPAA compliance features for healthcare. It provides enterprise-grade security, version control, audit trails, and integrations with EHR systems like Epic and Cerner to streamline healthcare document management. While versatile for general business use, its healthcare-specific capabilities make it suitable for handling protected health information (PHI) securely across teams.

Egnyte is a cloud-based enterprise content management platform specializing in secure file sharing, storage, and collaboration for regulated industries like healthcare. It provides HIPAA-compliant features including encrypted data at rest and in transit, comprehensive audit trails, and automated retention policies to manage sensitive patient documents and records. The solution integrates with tools like Microsoft 365 and offers AI-driven search, governance, and ransomware protection to streamline workflows while ensuring compliance.

iManage is an enterprise-grade document and email management platform that provides secure storage, version control, and intelligent search for critical business documents. In healthcare settings, it supports HIPAA compliance through robust security features like encryption, audit trails, and granular access controls. It excels in integrating with Microsoft 365 and Outlook for seamless workflow automation and collaboration among healthcare administrators and compliance teams.