Top 10 Best Healthcare Claims Software of 2026

Waystar is a premier cloud-based revenue cycle management (RCM) platform tailored for healthcare providers, specializing in end-to-end claims processing, submission, and denial management. It leverages AI and automation to verify eligibility, scrub claims for errors, and accelerate reimbursements while integrating seamlessly with EHRs and billing systems. The software delivers actionable analytics through its RevView platform, helping organizations optimize financial performance and reduce administrative burdens.

Availity is a leading healthcare revenue cycle management platform that specializes in claims processing, connecting providers with over 3,000 payers through its extensive network. It enables electronic claims submission, real-time eligibility verification, status tracking, and electronic remittance advice (ERA) to streamline workflows and reduce denials. The software also offers advanced claims editing, analytics, and patient payment solutions to optimize financial outcomes for healthcare organizations.

Athenahealth's athenaOne platform provides comprehensive healthcare claims management as part of its cloud-based EHR and revenue cycle management suite, automating claims submission, scrubbing, and tracking to reduce denials and speed up reimbursements. It includes real-time eligibility verification, denial management workflows, and advanced analytics drawn from a vast network of encounters for benchmarking performance. The solution integrates seamlessly with practice management tools, offering end-to-end visibility into the revenue cycle.

Kareo is a cloud-based healthcare platform specializing in revenue cycle management, medical billing, and practice management for independent practices. It automates claims submission, scrubbing, tracking, and denial management to streamline reimbursements and reduce administrative burdens. Integrated with EHR and patient payment tools, it helps practices improve cash flow and operational efficiency.

AdvancedMD is a comprehensive cloud-based EHR and practice management platform with robust healthcare claims processing capabilities, enabling electronic claims submission, scrubbing, and denial management. It streamlines the revenue cycle by automating claims workflows, integrating with clearinghouses, and providing real-time tracking and ERA posting. Suited for medical practices, it supports multi-location operations and offers analytics to optimize reimbursements.

Change Healthcare offers a robust claims management platform that automates electronic claims submission, adjudication, and payment reconciliation for healthcare providers and payers. It features advanced claims scrubbing, denial management, and EDI connectivity to thousands of payers, reducing errors and accelerating reimbursements. The solution integrates with EHRs and practice management systems to streamline the entire revenue cycle.

NextGen Healthcare offers a comprehensive suite of electronic health records (EHR) and practice management software, with robust healthcare claims processing capabilities integrated into its platform. The solution handles claims submission, scrubbing, eligibility verification, denial management, and revenue cycle management (RCM) for ambulatory practices and specialty groups. It emphasizes interoperability, compliance with HIPAA and MIPS, and automation to streamline billing workflows and reduce errors.

eClinicalWorks is a comprehensive EHR and practice management platform with robust healthcare claims processing features, enabling electronic claims submission, scrubbing, and denial management. It integrates billing workflows with patient records to streamline revenue cycle management for medical practices. The software supports eligibility verification, payment posting, and analytics for optimizing reimbursements.

DrChrono is a cloud-based EHR and practice management platform with robust healthcare claims processing capabilities, enabling electronic claims submission, scrubbing, and tracking. It integrates eligibility verification, ERA auto-posting, and denial management to streamline revenue cycle workflows for providers. The system supports multi-specialty practices with mobile access via iPad and web apps, reducing administrative burdens.

Office Ally is a web-based healthcare claims clearinghouse that simplifies electronic claims submission, eligibility verification, and remittance processing for medical practices. It supports CMS-1500 and UB-04 forms for thousands of payers, including Medicare and major insurers, with tools for claims scrubbing, denial management, and ERA/EFT posting. Ideal for streamlining billing workflows without expensive software installations, it focuses on affordability and basic efficiency for claims handling.