Quick Overview
- 1#1: Kareo - Cloud-based medical billing and practice management software that automates claims processing, denial management, and revenue cycle workflows.
- 2#2: AdvancedMD - Comprehensive billing solution with electronic claims submission, patient payments, and analytics for healthcare practices.
- 3#3: athenahealth - Integrated revenue cycle management platform that handles claims, eligibility verification, and AR follow-up seamlessly.
- 4#4: Waystar - Revenue cycle management tool specializing in claims scrubbing, payer negotiations, and patient payment optimization.
- 5#5: DrChrono - All-in-one EHR with robust medical billing features for superbill generation, superbills, and multi-location support.
- 6#6: Practice Fusion - Free EHR platform with integrated billing for claims management and payment posting tailored to small practices.
- 7#7: eClinicalWorks - EHR-integrated billing system offering automated claims, remittance processing, and reporting for diverse specialties.
- 8#8: NextGen Healthcare - Enterprise-grade healthcare software with advanced revenue cycle management, coding, and compliance tools.
- 9#9: CureMD - Cloud-based practice management and billing software with real-time claims tracking and denial prevention.
- 10#10: Greenway Health - Ambulatory RCM solution providing end-to-end billing, patient engagement, and interoperability features.
Tools were rigorously evaluated based on functionality (automation, integration), reliability in streamlining workflows, user-friendliness, and overall value, ensuring relevance for practices of all sizes and specialties.
Comparison Table
This comparison table examines key features, usability, and integration strengths of popular healthcare billing software tools like Kareo, AdvancedMD, athenahealth, Waystar, and DrChrono. Readers will discover critical details to select the right tool for their practice, whether prioritizing efficiency, cost, or specialized functionality.
| # | Tool | Category | Overall | Features | Ease of Use | Value |
|---|---|---|---|---|---|---|
| 1 | Kareo Cloud-based medical billing and practice management software that automates claims processing, denial management, and revenue cycle workflows. | specialized | 9.2/10 | 9.5/10 | 8.8/10 | 8.5/10 |
| 2 | AdvancedMD Comprehensive billing solution with electronic claims submission, patient payments, and analytics for healthcare practices. | enterprise | 9.1/10 | 9.5/10 | 8.2/10 | 8.6/10 |
| 3 | athenahealth Integrated revenue cycle management platform that handles claims, eligibility verification, and AR follow-up seamlessly. | enterprise | 8.7/10 | 9.2/10 | 7.8/10 | 8.1/10 |
| 4 | Waystar Revenue cycle management tool specializing in claims scrubbing, payer negotiations, and patient payment optimization. | specialized | 8.7/10 | 9.2/10 | 7.9/10 | 8.1/10 |
| 5 | DrChrono All-in-one EHR with robust medical billing features for superbill generation, superbills, and multi-location support. | specialized | 8.1/10 | 8.4/10 | 7.7/10 | 7.6/10 |
| 6 | Practice Fusion Free EHR platform with integrated billing for claims management and payment posting tailored to small practices. | specialized | 7.1/10 | 6.5/10 | 8.3/10 | 9.4/10 |
| 7 | eClinicalWorks EHR-integrated billing system offering automated claims, remittance processing, and reporting for diverse specialties. | enterprise | 7.4/10 | 8.2/10 | 6.5/10 | 7.0/10 |
| 8 | NextGen Healthcare Enterprise-grade healthcare software with advanced revenue cycle management, coding, and compliance tools. | enterprise | 8.2/10 | 9.1/10 | 7.3/10 | 7.8/10 |
| 9 | CureMD Cloud-based practice management and billing software with real-time claims tracking and denial prevention. | specialized | 8.4/10 | 9.1/10 | 7.6/10 | 8.0/10 |
| 10 | Greenway Health Ambulatory RCM solution providing end-to-end billing, patient engagement, and interoperability features. | enterprise | 7.6/10 | 8.1/10 | 6.9/10 | 7.3/10 |
Cloud-based medical billing and practice management software that automates claims processing, denial management, and revenue cycle workflows.
Comprehensive billing solution with electronic claims submission, patient payments, and analytics for healthcare practices.
Integrated revenue cycle management platform that handles claims, eligibility verification, and AR follow-up seamlessly.
Revenue cycle management tool specializing in claims scrubbing, payer negotiations, and patient payment optimization.
All-in-one EHR with robust medical billing features for superbill generation, superbills, and multi-location support.
Free EHR platform with integrated billing for claims management and payment posting tailored to small practices.
EHR-integrated billing system offering automated claims, remittance processing, and reporting for diverse specialties.
Enterprise-grade healthcare software with advanced revenue cycle management, coding, and compliance tools.
Cloud-based practice management and billing software with real-time claims tracking and denial prevention.
Ambulatory RCM solution providing end-to-end billing, patient engagement, and interoperability features.
Kareo
specializedCloud-based medical billing and practice management software that automates claims processing, denial management, and revenue cycle workflows.
AI-driven Intelligent Claims Scrubber that prevents denials proactively with payer-specific rules
Kareo is a cloud-based healthcare platform specializing in medical billing, revenue cycle management, practice management, and EHR for independent practices. It automates claims submission, eligibility verification, payment posting, and denial management to maximize reimbursements and streamline workflows. With robust reporting and patient engagement tools, Kareo helps practices reduce administrative burdens and improve financial performance.
Pros
- Automated claims scrubbing with high first-pass acceptance rates (up to 99%)
- Integrated ERA auto-posting and denial management workflows
- Real-time eligibility verification and patient payment collections
Cons
- Pricing can be steep for smaller practices with per-claim fees
- Customer support response times vary during peak periods
- Limited customization in advanced reporting compared to enterprise solutions
Best For
Independent medical and behavioral health practices looking for an all-in-one billing and practice management solution.
Pricing
Starts at $110/provider/month for core billing, plus $0.35-$0.50 per claim and setup fees; tiered plans scale with volume.
AdvancedMD
enterpriseComprehensive billing solution with electronic claims submission, patient payments, and analytics for healthcare practices.
AI-powered denial prevention and intelligent claims editing for highest clean claim rates
AdvancedMD is a comprehensive cloud-based platform offering integrated healthcare billing software alongside EHR and practice management tools. It excels in revenue cycle management, automating claims submission, scrubbing, denial management, and patient payments to maximize reimbursements. With real-time eligibility checks and robust reporting, it supports medical practices in streamlining financial workflows and reducing errors.
Pros
- Advanced claims scrubbing and automated denial management reduce errors and speed up reimbursements
- Seamless integration with EHR and major clearinghouses for efficient workflows
- Comprehensive analytics and reporting for revenue optimization
Cons
- High pricing can be prohibitive for small practices
- Steep learning curve for full customization and setup
- Mixed customer support experiences with occasional delays
Best For
Mid-sized to large medical practices seeking an all-in-one billing solution integrated with EHR.
Pricing
Custom quotes starting at $400-$700 per provider/month, plus setup fees and add-ons for advanced modules.
athenahealth
enterpriseIntegrated revenue cycle management platform that handles claims, eligibility verification, and AR follow-up seamlessly.
AI-powered Revenue Intelligence that proactively predicts denials and optimizes collections
Athenahealth is a comprehensive cloud-based platform providing electronic health records (EHR), practice management, and advanced revenue cycle management (RCM) tailored for healthcare providers. Its billing software automates claims submission, scrubbing, denial management, and payment posting to optimize reimbursements and reduce errors. With strong interoperability via athenahealth's network, it enables efficient data exchange and analytics-driven insights for financial performance.
Pros
- Robust RCM with high clean claims rates (often 95%+ first-pass acceptance)
- Seamless integration with EHR and patient engagement tools
- Advanced analytics and reporting for denial trends and revenue forecasting
Cons
- High subscription costs that can strain smaller practices
- Steep learning curve and complex interface for new users
- Occasional customer support delays during peak issues
Best For
Mid-sized to large medical practices and specialty groups needing integrated EHR and high-performance billing solutions.
Pricing
Custom subscription pricing, typically $300-$700 per provider/month including RCM modules, with implementation fees and add-ons.
Waystar
specializedRevenue cycle management tool specializing in claims scrubbing, payer negotiations, and patient payment optimization.
AI-driven Denial Intelligence that predicts and prevents denials before submission, boosting clean claim rates significantly.
Waystar is a comprehensive revenue cycle management (RCM) platform tailored for healthcare providers, specializing in healthcare billing, claims processing, and payment optimization. It automates claims submission, denial management, patient collections, and provides AI-driven analytics to improve financial outcomes. The solution integrates seamlessly with major EHR systems and handles high-volume transactions for hospitals and large practices.
Pros
- Robust AI-powered denial prevention and analytics
- High-volume claims processing with 99%+ acceptance rates
- Extensive integrations with EHRs and PMS systems
Cons
- Enterprise-focused pricing excludes small practices
- Steep learning curve for full customization
- Implementation can take several months
Best For
Mid-to-large healthcare organizations and hospitals seeking scalable, end-to-end RCM solutions.
Pricing
Custom quote-based pricing, typically subscription with per-claim fees or percentage of collections (starting around $0.20-$0.50 per claim for high volume).
DrChrono
specializedAll-in-one EHR with robust medical billing features for superbill generation, superbills, and multi-location support.
Integrated revenue cycle dashboard with AI-driven denial prediction and resolution tools
DrChrono is a cloud-based electronic health records (EHR) and practice management platform with integrated healthcare billing capabilities, enabling providers to manage claims submission, payment posting, denial management, and patient collections efficiently. It automates revenue cycle tasks like eligibility verification and ERA posting while integrating seamlessly with clinical workflows. Designed for specialty practices, it supports customizable billing rules and reporting to optimize financial performance.
Pros
- Seamless EHR-billing integration reduces errors and speeds up reimbursements
- Real-time eligibility checks and automated claims scrubbing improve clean claim rates
- Mobile app allows billing tasks on-the-go for providers
Cons
- Pricing can be steep for smaller practices with per-provider costs
- Steep learning curve for advanced billing customizations
- Customer support response times vary, especially for complex issues
Best For
Small to mid-sized medical practices needing an all-in-one EHR with robust billing automation.
Pricing
Starts at $199 per provider/month for basic plans, up to $439+ for enterprise with custom quotes; includes setup fees.
Practice Fusion
specializedFree EHR platform with integrated billing for claims management and payment posting tailored to small practices.
Fully free EHR with built-in billing, eliminating upfront costs for essential claims and superbill functionality
Practice Fusion is a cloud-based electronic health record (EHR) platform that includes integrated healthcare billing features like superbill generation, electronic claims submission, and payment tracking. Designed primarily for small to mid-sized medical practices, it streamlines billing within the context of patient charting, scheduling, and e-prescribing. While not a standalone billing solution, its free model makes it accessible for practices seeking basic revenue cycle management tied to EHR workflows.
Pros
- Completely free core platform with no subscription fees
- Seamless integration of billing with EHR and practice management
- Intuitive interface that simplifies claims submission for beginners
Cons
- Limited advanced billing tools like full RCM or denial management
- Relies on third-party clearinghouses for claims processing
- Customer support can be slow and less responsive for billing issues
Best For
Small independent practices or solo providers needing cost-free, basic billing integrated with everyday EHR tasks.
Pricing
100% free for core EHR and billing features; optional paid integrations or premium support available.
eClinicalWorks
enterpriseEHR-integrated billing system offering automated claims, remittance processing, and reporting for diverse specialties.
Integrated Revenue Cycle Management with AI-driven predictive analytics for claims accuracy and faster reimbursements
eClinicalWorks is a cloud-based EHR and practice management platform with integrated healthcare billing solutions, offering tools for claims processing, revenue cycle management (RCM), eligibility verification, and denial management. It automates electronic claims submission to major payers, tracks accounts receivable, and provides analytics to optimize reimbursements. Suitable for ambulatory practices, it combines billing with patient records for streamlined workflows.
Pros
- Comprehensive RCM with automated claims scrubbing and denial prevention
- Seamless EHR-billing integration reducing manual data entry
- Advanced analytics and reporting for revenue optimization
Cons
- Steep learning curve and clunky interface for billing tasks
- Custom pricing can be expensive with high implementation costs
- Inconsistent customer support and frequent software updates causing disruptions
Best For
Mid-sized to large ambulatory practices and FQHCs needing an all-in-one EHR platform with robust billing capabilities.
Pricing
Quote-based subscription starting at $399-$699 per provider/month, plus implementation fees and optional add-ons.
NextGen Healthcare
enterpriseEnterprise-grade healthcare software with advanced revenue cycle management, coding, and compliance tools.
Precision Claims scrubbing engine that uses AI to predict and prevent denials before submission
NextGen Healthcare offers a comprehensive EHR and practice management platform with robust revenue cycle management (RCM) tools tailored for healthcare billing. It handles claims processing, denial management, eligibility verification, payment posting, and analytics to optimize reimbursements. Designed primarily for ambulatory and specialty practices, it integrates seamlessly with clinical workflows to minimize billing errors and accelerate cash flow.
Pros
- Advanced denial management and claims scrubbing for high first-pass acceptance rates
- Deep integration with EHR for automated charge capture and coding
- Powerful analytics and reporting for revenue optimization
Cons
- Steep learning curve and complex interface for new users
- Lengthy and costly implementation process
- Premium pricing that may not suit small practices
Best For
Mid-sized to large specialty practices needing an integrated EHR and billing solution with enterprise-level RCM capabilities.
Pricing
Custom enterprise pricing, typically $300-$600 per provider/month plus implementation fees; quotes required based on practice size and modules.
CureMD
specializedCloud-based practice management and billing software with real-time claims tracking and denial prevention.
AI-driven claims intelligence that proactively identifies and resolves billing errors to maximize reimbursements
CureMD is a cloud-based Electronic Health Records (EHR) and practice management platform with robust healthcare billing features, including revenue cycle management, electronic claims submission, and denial tracking. It integrates patient records seamlessly with billing workflows to automate eligibility verification, charge capture, and payment posting. Designed for specialty practices, it supports HIPAA compliance and offers analytics for financial performance optimization.
Pros
- Comprehensive revenue cycle management with automated claims scrubbing
- Seamless integration of EHR and billing to reduce errors
- Customizable reporting and analytics for billing insights
Cons
- Steep learning curve for new users due to extensive features
- Customer support response times can be inconsistent
- Higher costs for smaller practices with limited customization needs
Best For
Mid-sized specialty practices needing an all-in-one EHR and advanced billing solution.
Pricing
Quote-based pricing starting at around $300 per provider per month, with tiers for additional modules like advanced RCM.
Greenway Health
enterpriseAmbulatory RCM solution providing end-to-end billing, patient engagement, and interoperability features.
AI-powered revenue intelligence for predictive denial prevention and optimized reimbursements
Greenway Health offers Intergy, an integrated EHR and practice management platform with comprehensive healthcare billing features tailored for ambulatory practices. It streamlines revenue cycle management, including claims processing, electronic remittance advice, denial management, and patient eligibility verification. The software emphasizes interoperability and compliance with healthcare standards like HIPAA and MIPS, supporting specialties such as cardiology and orthopedics.
Pros
- Integrated EHR and billing reduces data entry errors
- Strong claims scrubbing and denial management tools
- Customizable workflows for various medical specialties
Cons
- Steep learning curve for new users
- Implementation can be lengthy and costly
- Customer support response times vary
Best For
Small to mid-sized ambulatory practices needing an all-in-one solution for clinical documentation and billing.
Pricing
Custom quote-based pricing; typically $300-$600 per provider/month for core EHR and billing modules, plus implementation fees.
Conclusion
The reviewed healthcare billing software standout in innovation, with Kareo leading as the top choice for its seamless automation of claims processing, denial management, and revenue workflows. AdvancedMD and athenahealth follow closely, offering comprehensive features and integrated solutions that cater to distinct practice needs, ensuring there’s a strong option for every healthcare provider.
Don’t miss out on optimizing your practice—start with Kareo to experience streamlined billing and enhanced efficiency firsthand.
Tools Reviewed
All tools were independently evaluated for this comparison