Top 10 Best Gastroenterology Billing Software of 2026

gGastro by Modernizing Medicine is a cloud-based, specialty-specific EHR and practice management platform designed exclusively for gastroenterology practices, with robust billing capabilities integrated throughout. It automates coding for complex GI procedures like endoscopies, colonoscopies, and biopsies, streamlines claims submission, and provides revenue cycle management tools to maximize reimbursements and reduce denials. The system ensures HIPAA compliance and MIPS eligibility through AI-driven features like NotaScore.

AmkaiPractice is a specialized practice management and billing software designed exclusively for gastroenterology and GI anesthesia practices, offering seamless integration with EHR systems like AmkaiEndoscopy. It handles complex GI-specific billing tasks, including accurate CPT and modifier coding for procedures such as colonoscopies, EUS, and ERCPs, along with revenue cycle management, claims scrubbing, and denial resolution. The platform emphasizes compliance with GI payer requirements and provides robust reporting for financial optimization in high-volume endoscopy centers.

Provation MD is a specialized procedure documentation and coding software tailored for gastroenterology, enabling physicians to create structured endoscopy reports quickly and accurately. It automates charge capture, HCC and CPT coding, and integrates seamlessly with EHRs and billing systems to streamline reimbursement processes. By focusing on compliant documentation, it minimizes coding errors and maximizes revenue for GI practices, though it excels more in documentation than full-cycle billing.

EndoSoft is a specialized endoscopy management system tailored for gastroenterology practices, offering end-to-end workflow support from procedure documentation to billing. It captures high-quality images and videos, generates detailed reports with automated CPT and ICD-10 coding, and streamlines charge capture for efficient claims submission. The software integrates with practice management systems to reduce billing errors and improve reimbursement rates in GI settings.

Kareo Billing is a cloud-based revenue cycle management platform that automates claims processing, payment posting, and denial management for medical practices, including gastroenterology. It supports complex procedural coding for GI services like colonoscopies and endoscopies with built-in scrubbing and compliance checks. The software integrates with popular EHRs and offers patient payment portals to improve collections.

AdvancedMD Billing is a comprehensive cloud-based platform designed for medical billing and revenue cycle management, tailored for specialties like gastroenterology through support for complex procedure codes such as colonoscopies, endoscopies, and modifier billing. It automates claims submission, tracks accounts receivable, handles denial management, and integrates seamlessly with EHR systems for accurate coding and compliance. The software provides detailed reporting and analytics to optimize reimbursements for GI practices.

athenaOne by athenahealth is a cloud-based EHR and practice management platform with integrated revenue cycle management designed for specialties like gastroenterology. It automates billing processes including claims submission, scrubbing, and denial management, supporting GI-specific CPT and ICD-10 codes for procedures such as colonoscopies, endoscopies, and biopsies. The system leverages real-time data from patient encounters to streamline accurate coding and reimbursement, while ensuring HIPAA compliance and interoperability.

eClinicalWorks is a comprehensive EHR and practice management platform with integrated billing capabilities designed to support specialties like gastroenterology. It handles complex GI procedure coding for endoscopies, colonoscopies, and related services, automates claims submission to major payers, and includes tools for denial management, AR follow-up, and financial reporting. The system streamlines revenue cycle management by linking patient encounters directly to billing workflows, reducing errors and improving cash flow for gastro practices.

NextGen Office is a cloud-based EHR and practice management platform from NextGen Healthcare, tailored for specialty practices including gastroenterology. It offers robust billing capabilities with automated claims processing, denial management, and support for complex GI procedure coding like colonoscopies and endoscopies. The solution integrates clinical documentation directly with revenue cycle management to improve accuracy and reimbursement efficiency.

DrChrono is a cloud-based EHR and practice management platform with integrated billing capabilities designed for medical specialties, including gastroenterology. It supports GI-specific workflows through customizable templates for procedures like colonoscopies, endoscopies, and biopsies, alongside features for claims submission, scrubbing, and revenue cycle management. The software emphasizes mobility with iOS-native apps, enabling on-the-go charge capture and billing tasks for busy gastro practices.