Quick Overview
- 1#1: Kareo - Cloud-based medical billing and revenue cycle management platform designed for independent practices to streamline claims and payments.
- 2#2: AdvancedMD - Comprehensive cloud-based EHR and medical billing software that automates claims processing and practice management.
- 3#3: athenahealth - Cloud-based EHR and practice management suite with advanced medical billing and revenue cycle optimization for all practice sizes.
- 4#4: DrChrono - Mobile-first cloud-based EHR platform with integrated medical billing, scheduling, and telehealth features.
- 5#5: Practice Fusion - Free cloud-based EHR with built-in medical billing tools for claims submission and patient payments.
- 6#6: eClinicalWorks - Cloud-based EHR and practice management system featuring robust medical billing and interoperability capabilities.
- 7#7: NextGen Healthcare - Cloud-based healthcare IT solutions including EHR and specialized medical billing for ambulatory practices.
- 8#8: CureMD - All-in-one cloud-based EHR, practice management, and medical billing software with patient portal integration.
- 9#9: CharmHealth - Cloud-based EHR and practice management platform with efficient medical billing and MIPS reporting tools.
- 10#10: CollaborateMD - Cloud-based medical billing software focused on claims management, patient statements, and AR recovery.
We ranked these tools by evaluating features like claims automation, interoperability, and patient payment support, alongside usability, reliability, and overall value, ensuring each entry meets the dynamic needs of contemporary healthcare operations.
Comparison Table
Cloud-based medical billing software simplifies practice operations, and this comparison table explores top tools like Kareo, AdvancedMD, athenahealth, DrChrono, Practice Fusion, and more. Readers will discover insights into each platform’s features, pricing structures, and usability to find the best fit for their practice’s needs.
| # | Tool | Category | Overall | Features | Ease of Use | Value |
|---|---|---|---|---|---|---|
| 1 | Kareo Cloud-based medical billing and revenue cycle management platform designed for independent practices to streamline claims and payments. | specialized | 9.4/10 | 9.6/10 | 9.0/10 | 9.2/10 |
| 2 | AdvancedMD Comprehensive cloud-based EHR and medical billing software that automates claims processing and practice management. | enterprise | 8.8/10 | 9.2/10 | 8.0/10 | 8.4/10 |
| 3 | athenahealth Cloud-based EHR and practice management suite with advanced medical billing and revenue cycle optimization for all practice sizes. | enterprise | 8.7/10 | 9.2/10 | 7.9/10 | 8.1/10 |
| 4 | DrChrono Mobile-first cloud-based EHR platform with integrated medical billing, scheduling, and telehealth features. | specialized | 8.7/10 | 9.2/10 | 8.4/10 | 8.1/10 |
| 5 | Practice Fusion Free cloud-based EHR with built-in medical billing tools for claims submission and patient payments. | specialized | 7.6/10 | 7.2/10 | 8.1/10 | 9.3/10 |
| 6 | eClinicalWorks Cloud-based EHR and practice management system featuring robust medical billing and interoperability capabilities. | enterprise | 8.1/10 | 8.6/10 | 6.8/10 | 7.4/10 |
| 7 | NextGen Healthcare Cloud-based healthcare IT solutions including EHR and specialized medical billing for ambulatory practices. | enterprise | 8.4/10 | 9.1/10 | 7.6/10 | 8.0/10 |
| 8 | CureMD All-in-one cloud-based EHR, practice management, and medical billing software with patient portal integration. | specialized | 8.2/10 | 8.7/10 | 7.9/10 | 8.0/10 |
| 9 | CharmHealth Cloud-based EHR and practice management platform with efficient medical billing and MIPS reporting tools. | specialized | 8.6/10 | 8.8/10 | 9.1/10 | 8.3/10 |
| 10 | CollaborateMD Cloud-based medical billing software focused on claims management, patient statements, and AR recovery. | specialized | 8.4/10 | 8.7/10 | 8.2/10 | 8.0/10 |
Cloud-based medical billing and revenue cycle management platform designed for independent practices to streamline claims and payments.
Comprehensive cloud-based EHR and medical billing software that automates claims processing and practice management.
Cloud-based EHR and practice management suite with advanced medical billing and revenue cycle optimization for all practice sizes.
Mobile-first cloud-based EHR platform with integrated medical billing, scheduling, and telehealth features.
Free cloud-based EHR with built-in medical billing tools for claims submission and patient payments.
Cloud-based EHR and practice management system featuring robust medical billing and interoperability capabilities.
Cloud-based healthcare IT solutions including EHR and specialized medical billing for ambulatory practices.
All-in-one cloud-based EHR, practice management, and medical billing software with patient portal integration.
Cloud-based EHR and practice management platform with efficient medical billing and MIPS reporting tools.
Cloud-based medical billing software focused on claims management, patient statements, and AR recovery.
Kareo
specializedCloud-based medical billing and revenue cycle management platform designed for independent practices to streamline claims and payments.
Revenue Cycle Intelligence with AI-powered denial prediction and automated recovery
Kareo is a comprehensive cloud-based medical billing software platform designed specifically for independent healthcare practices to streamline revenue cycle management. It automates claims submission and scrubbing, handles eligibility verification, denial management, and patient payments while integrating seamlessly with EHR and practice management systems. With real-time analytics and mobile accessibility, Kareo helps maximize reimbursements and reduce administrative overhead for providers.
Pros
- Advanced automation for claims processing and denial prevention
- Robust analytics and reporting for revenue optimization
- Seamless cloud access with strong EHR integrations
Cons
- Pricing can be steep for very small practices
- Initial setup requires some training
- Occasional delays in customer support response
Best For
Small to mid-sized independent medical practices needing an all-in-one cloud billing solution.
Pricing
Starts at $110/provider/month for core billing, with tiered plans (Essentials, Plus, Pro) scaling to $500+/provider/month; includes per-claim fees.
AdvancedMD
enterpriseComprehensive cloud-based EHR and medical billing software that automates claims processing and practice management.
AI-powered revenue cycle management with predictive denial prevention and automated scrubbing
AdvancedMD is a comprehensive cloud-based medical billing software integrated with EHR and practice management tools, designed to streamline revenue cycle management for healthcare providers. It automates claims submission, eligibility verification, denial management, and patient payments, supporting over 60 specialties. The platform offers real-time analytics, customizable reporting, and scalability for single-provider practices to large enterprises, ensuring faster reimbursements and compliance with HIPAA standards.
Pros
- Seamless integration of billing with EHR and scheduling
- Advanced denial management and revenue cycle analytics
- Scalable for multi-location and specialty practices
Cons
- Higher pricing for smaller practices
- Steep learning curve for advanced features
- Customer support response times can vary
Best For
Medium to large medical practices needing an all-in-one cloud platform for efficient billing and practice management.
Pricing
Custom pricing starting at around $400-$600 per provider/month, depending on modules and practice size; includes implementation fees.
athenahealth
enterpriseCloud-based EHR and practice management suite with advanced medical billing and revenue cycle optimization for all practice sizes.
AI-powered Revenue Intelligence that proactively identifies and resolves billing issues before submission
athenahealth is a leading cloud-based platform offering integrated EHR, practice management, and revenue cycle management (RCM) solutions tailored for medical practices. Its medical billing software excels in automating claims submission, scrubbing, eligibility checks, denial management, and payment posting to optimize revenue capture. With advanced analytics and interoperability via FHIR standards, it provides actionable insights to reduce AR days and improve financial performance for healthcare providers.
Pros
- Robust automation for claims processing and denial prevention with AI insights
- Seamless integration with EHR and payer networks for high first-pass acceptance rates
- Comprehensive analytics dashboard for revenue cycle performance tracking
Cons
- High implementation costs and subscription fees
- Steep learning curve for new users due to extensive features
- Limited flexibility for highly customized workflows
Best For
Medium to large medical practices needing an integrated cloud-based EHR and billing solution with strong payer connectivity.
Pricing
Custom quote-based pricing; typically $400-$600 per provider per month for full RCM suite, plus implementation fees.
DrChrono
specializedMobile-first cloud-based EHR platform with integrated medical billing, scheduling, and telehealth features.
Real-time insurance eligibility checks and automated superbills directly from patient encounters
DrChrono is a cloud-based electronic health record (EHR) and practice management platform with robust medical billing capabilities, enabling automated claims submission, real-time insurance eligibility checks, and revenue cycle management. It integrates billing seamlessly with patient charting, scheduling, and telehealth, reducing administrative burdens for healthcare providers. Designed for small to mid-sized practices, it supports specialty-specific workflows and ensures HIPAA compliance across all features.
Pros
- Comprehensive integrated billing with EHR for streamlined workflows
- Real-time eligibility verification and automated claims scrubbing
- Strong mobile and iPad support for on-the-go billing
Cons
- Pricing can be steep for smaller practices without customization options
- Occasional reports of billing glitches during peak usage
- Customer support response times vary by subscription tier
Best For
Small to medium-sized medical practices seeking an all-in-one cloud solution for EHR and billing with mobile flexibility.
Pricing
Custom subscription pricing starting at around $200 per provider per month, with tiers scaling based on features and users; includes setup fees.
Practice Fusion
specializedFree cloud-based EHR with built-in medical billing tools for claims submission and patient payments.
Free forever cloud-based billing integrated with full EHR, eliminating subscription costs for essential revenue cycle management
Practice Fusion is a cloud-based electronic health record (EHR) platform with integrated medical billing features, enabling practices to create superbills, verify insurance eligibility, submit claims electronically, and post payments directly from the web interface. It supports standard codes like ICD-10 and CPT/HCPCS, integrates with major clearinghouses, and offers tools for denial management and reporting. While primarily an EHR solution, its billing module streamlines revenue cycle tasks for small practices without requiring on-premise hardware.
Pros
- Completely free core EHR and billing functionality
- Seamless integration between clinical documentation and billing workflows
- Cloud accessibility from any device with no installation needed
Cons
- Billing features lack advanced customization and analytics compared to dedicated solutions
- Customer support can be slow and ticket-based
- Occasional interface ads and upsell prompts disrupt workflow
Best For
Small to mid-sized independent practices seeking a no-cost, integrated cloud EHR with basic billing capabilities.
Pricing
Free for unlimited users and core features; premium support and advanced tools available for $149/provider/month.
eClinicalWorks
enterpriseCloud-based EHR and practice management system featuring robust medical billing and interoperability capabilities.
AI-powered claims optimization and denial prediction in its Revenue Cycle Management suite
eClinicalWorks is a comprehensive cloud-based EHR and practice management platform with integrated medical billing capabilities, designed to streamline revenue cycle management for healthcare providers. It offers automated claims submission, scrubbing, denial management, eligibility verification, and AR tracking to optimize reimbursements and reduce administrative burdens. The system integrates seamlessly with its EHR for accurate coding and supports multi-specialty practices with scalable billing tools.
Pros
- Seamless integration with EHR for accurate billing and coding
- Robust revenue cycle management with claims scrubbing and analytics
- Cloud-based accessibility with strong HIPAA compliance and security
- Scalable for multi-location and multi-provider practices
Cons
- Steep learning curve and outdated user interface
- Customer support response times can be slow
- Custom pricing lacks transparency and can be expensive for small practices
- Occasional glitches in claims processing reported by users
Best For
Medium to large medical practices needing an integrated cloud-based EHR and billing solution for efficient revenue cycle management.
Pricing
Quote-based pricing, typically $400-$600 per provider per month plus implementation fees and add-ons for advanced modules.
NextGen Healthcare
enterpriseCloud-based healthcare IT solutions including EHR and specialized medical billing for ambulatory practices.
AI-powered denial management with predictive analytics to proactively reduce claim rejections
NextGen Healthcare provides a comprehensive cloud-based EHR and practice management platform with robust revenue cycle management (RCM) tools tailored for medical billing. It automates claims submission, eligibility verification, denial management, and payment posting while integrating seamlessly with electronic health records for streamlined workflows. The solution offers advanced analytics and reporting to optimize revenue capture and compliance for healthcare providers.
Pros
- Comprehensive RCM with automated claims scrubbing and denial prevention
- Deep integration with EHR for end-to-end practice management
- Advanced analytics and customizable reporting for revenue optimization
Cons
- Steep learning curve and complex interface for new users
- High implementation time and costs for customization
- Pricing can be premium for smaller practices
Best For
Mid-sized to large specialty practices needing integrated EHR and advanced billing automation.
Pricing
Custom enterprise pricing, typically $300-$600 per provider/month plus implementation fees; quotes required.
CureMD
specializedAll-in-one cloud-based EHR, practice management, and medical billing software with patient portal integration.
AI-powered claims intelligence and predictive denial prevention for superior reimbursement rates
CureMD is a comprehensive cloud-based platform offering electronic health records (EHR), practice management, and specialized medical billing solutions for healthcare providers. It automates revenue cycle management with features like real-time eligibility checks, claims scrubbing, electronic remittance advice (ERA), and denial management to maximize reimbursements and reduce errors. The software ensures HIPAA compliance and integrates seamlessly with EHR for efficient workflows across specialties.
Pros
- Robust revenue cycle management with automated claims processing and denial tracking
- Seamless integration with EHR and patient portal for streamlined operations
- Cloud accessibility with mobile support for on-the-go billing management
Cons
- Steep learning curve for non-tech-savvy users and smaller practices
- Custom pricing can be expensive for solo providers
- Occasional reports of slower customer support response times
Best For
Mid-sized medical practices needing an integrated cloud-based EHR and billing solution with strong revenue optimization tools.
Pricing
Custom quote-based pricing starting at around $300-$400 per provider per month, with scalable enterprise plans including setup fees.
CharmHealth
specializedCloud-based EHR and practice management platform with efficient medical billing and MIPS reporting tools.
Direct charting-to-billing integration that auto-populates claims from EHR notes to minimize errors
CharmHealth is a cloud-based EHR and practice management platform with integrated medical billing tools designed for healthcare providers. It streamlines claims submission, electronic remittance advice (ERA) posting, denial management, and revenue cycle reporting. The software supports multiple specialties and includes patient portal and telehealth features for comprehensive practice management.
Pros
- Intuitive user interface with minimal training required
- Seamless integration of EHR and billing workflows
- Strong customer support and regular updates
Cons
- Limited advanced analytics and custom reporting options
- Pricing scales quickly for multi-provider practices
- Some specialty-specific billing customizations are basic
Best For
Small to medium-sized medical practices seeking an affordable, all-in-one cloud-based solution for EHR and billing.
Pricing
Starts at $299/provider/month for basic features; Pro plan at $449/provider/month includes full billing and telehealth.
CollaborateMD
specializedCloud-based medical billing software focused on claims management, patient statements, and AR recovery.
Built-in claims scrubber that prevents denials before submission with 99% first-pass acceptance rate
CollaborateMD is a cloud-based medical billing software that automates revenue cycle management for healthcare practices, including electronic claims submission, denial scrubbing, and patient payments. It provides real-time reporting, eligibility verification, and integration with major EHR systems like Kareo and eClinicalWorks. The platform emphasizes efficiency in handling high claim volumes with minimal on-site hardware requirements.
Pros
- Comprehensive denial management and claims scrubbing
- Seamless EHR integrations and real-time analytics
- Reliable customer support with dedicated onboarding
Cons
- Pricing scales steeply with claim volume
- Limited advanced customization options
- Steeper learning curve for non-billing staff
Best For
Small to mid-sized medical practices seeking robust, scalable cloud billing without full RCM outsourcing.
Pricing
Starts at $399/month for up to 300 claims, with tiered plans up to $1,499/month for 5,000+ claims; add-ons for extras like patient portal.
Conclusion
Evaluating cloud-based medical billing software reveals standout tools, with Kareo leading as the top choice, streamlining claims and payments for independent practices. AdvancedMD and athenahealth follow closely, offering robust alternatives—AdvancedMD for its comprehensive EHR integration and automated processing, and athenahealth for its adaptability across practice sizes. Whether prioritizing specific features or broad functionality, the top three deliver solutions tailored to diverse needs.
Don’t hesitate to explore Kareo first—it sets the standard for efficiency in medical billing. If AdvancedMD or athenahealth better align with your practice’s unique workflows, they remain strong, proven options.
Tools Reviewed
All tools were independently evaluated for this comparison