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Healthcare Medicine

Top 10 Best Asc EHR Software of 2026

Top 10 best Asc EHR Software: Compare solutions, features, benefits. Find your perfect fit. Explore now.

Min-ji Park

Min-ji Park

Feb 11, 2026

10 tools comparedExpert reviewed
Independent evaluation · Unbiased commentary · Updated regularly
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Ambulatory surgery centers (ASCs) rely on robust Ehr Software to optimize operations, from clinical documentation to revenue cycle management, making the right tool selection a cornerstone of efficient, compliant practice. With diverse platforms tailored to ASC needs, our curated list distills the best options to guide informed decisions for practices of all sizes.

Quick Overview

  1. 1#1: Amkai ASC360 - Cloud-based EHR and practice management platform tailored specifically for ambulatory surgery centers with integrated scheduling and billing.
  2. 2#2: Surgical Information Systems (SIS) - Comprehensive perioperative software suite providing EHR, inventory management, and analytics for ASCs.
  3. 3#3: ORBIT - ASC-focused surgical scheduling and management software with EHR integration for streamlined operations.
  4. 4#4: Provation MD - Advanced clinical documentation and workflow tool that enhances EHR efficiency in ASC procedures.
  5. 5#5: Waystar - Revenue cycle management solution that seamlessly integrates with ASC EHR systems for optimized billing and claims.
  6. 6#6: athenaOne - Cloud-based EHR platform supporting ambulatory surgery centers with patient engagement and interoperability features.
  7. 7#7: NextGen Office - Specialty EHR and practice management system adaptable for ASC workflows and regulatory compliance.
  8. 8#8: AdvancedMD - All-in-one EHR, billing, and scheduling software designed for outpatient and surgery center practices.
  9. 9#9: Kareo - EHR and billing platform offering simplicity and value for independent ambulatory surgery centers.
  10. 10#10: eClinicalWorks - Robust EHR solution with telehealth and analytics features suitable for ASC environments.

We ranked these tools based on clinical functionality, integration strength, user experience, and value, ensuring a balanced assessment that combines technical excellence with practical relevance for ASC workflows.

Comparison Table

This comparison table explores key Asc Ehr Software tools, including Amkai ASC360, Surgical Information Systems (SIS), ORBIT, Provation MD, Waystar, and more, highlighting their features and use cases. Readers will gain clarity on how each tool aligns with different practice needs, from administrative tasks to specialized clinical workflows.

Cloud-based EHR and practice management platform tailored specifically for ambulatory surgery centers with integrated scheduling and billing.

Features
9.9/10
Ease
9.4/10
Value
9.2/10

Comprehensive perioperative software suite providing EHR, inventory management, and analytics for ASCs.

Features
9.5/10
Ease
8.4/10
Value
8.7/10
3ORBIT logo8.5/10

ASC-focused surgical scheduling and management software with EHR integration for streamlined operations.

Features
9.2/10
Ease
7.8/10
Value
8.3/10

Advanced clinical documentation and workflow tool that enhances EHR efficiency in ASC procedures.

Features
9.4/10
Ease
8.1/10
Value
7.9/10
5Waystar logo8.4/10

Revenue cycle management solution that seamlessly integrates with ASC EHR systems for optimized billing and claims.

Features
9.1/10
Ease
7.6/10
Value
8.2/10
6athenaOne logo8.4/10

Cloud-based EHR platform supporting ambulatory surgery centers with patient engagement and interoperability features.

Features
8.7/10
Ease
8.0/10
Value
7.9/10

Specialty EHR and practice management system adaptable for ASC workflows and regulatory compliance.

Features
8.7/10
Ease
7.4/10
Value
7.9/10
8AdvancedMD logo8.4/10

All-in-one EHR, billing, and scheduling software designed for outpatient and surgery center practices.

Features
8.7/10
Ease
8.2/10
Value
7.9/10
9Kareo logo8.1/10

EHR and billing platform offering simplicity and value for independent ambulatory surgery centers.

Features
7.9/10
Ease
8.5/10
Value
7.8/10

Robust EHR solution with telehealth and analytics features suitable for ASC environments.

Features
8.2/10
Ease
6.8/10
Value
7.0/10
1
Amkai ASC360 logo

Amkai ASC360

enterprise

Cloud-based EHR and practice management platform tailored specifically for ambulatory surgery centers with integrated scheduling and billing.

Overall Rating9.8/10
Features
9.9/10
Ease of Use
9.4/10
Value
9.2/10
Standout Feature

Fully integrated perioperative record that automates documentation from pre-op assessment to post-op follow-up, reducing errors and clinician burden

Amkai ASC360 is a cloud-based, ASC-specific EHR and practice management software tailored exclusively for ambulatory surgery centers. It provides end-to-end functionality including scheduling, perioperative documentation, revenue cycle management, inventory tracking, and compliance reporting. The platform integrates clinical, financial, and operational workflows into a single database, enabling efficient case management and data analytics for improved outcomes and profitability.

Pros

  • ASC-optimized workflows with specialized perioperative documentation
  • Seamless integration of EHR, billing, and analytics in one platform
  • Robust compliance tools and real-time reporting for MIPS and regulatory needs

Cons

  • Higher upfront implementation costs and training requirements
  • Pricing scales with case volume, potentially expensive for smaller ASCs
  • Limited customization for non-standard ASC procedures

Best For

Mid-to-large ambulatory surgery centers needing a comprehensive, ASC-focused EHR for streamlined surgical operations and revenue management.

Pricing

Custom subscription pricing based on case volume, users, and modules; typically starts at $500+ per month for small ASCs—contact for quote.

2
Surgical Information Systems (SIS) logo

Surgical Information Systems (SIS)

enterprise

Comprehensive perioperative software suite providing EHR, inventory management, and analytics for ASCs.

Overall Rating9.1/10
Features
9.5/10
Ease of Use
8.4/10
Value
8.7/10
Standout Feature

Integrated perioperative suite with real-time OR analytics and predictive scheduling

Surgical Information Systems (SIS) is a leading perioperative EHR solution designed specifically for ambulatory surgery centers (ASCs) and hospitals, streamlining surgical workflows from scheduling to billing. It offers comprehensive tools for operative documentation, inventory management, analytics, and revenue cycle management, ensuring compliance with ASC standards. SIS stands out for its deep integration across the perioperative continuum, reducing errors and improving operational efficiency in high-volume surgical environments.

Pros

  • Highly specialized perioperative EHR tailored for ASCs with robust OR scheduling and documentation
  • Advanced analytics and reporting for surgical performance and revenue optimization
  • Seamless integration with billing, inventory, and compliance tools

Cons

  • High initial implementation costs and customization fees
  • Steep learning curve for non-surgical staff
  • Limited scope outside perioperative settings

Best For

Ambulatory surgery centers seeking a comprehensive, surgery-focused EHR to enhance efficiency and compliance.

Pricing

Custom quote-based pricing starting at $100K+ annually for mid-sized ASCs, including implementation and support.

3
ORBIT logo

ORBIT

specialized

ASC-focused surgical scheduling and management software with EHR integration for streamlined operations.

Overall Rating8.5/10
Features
9.2/10
Ease of Use
7.8/10
Value
8.3/10
Standout Feature

Advanced block time scheduler with AI-driven utilization forecasting to maximize OR efficiency

ORBIT by Orbit Surgical is a cloud-based EHR and practice management platform tailored for Ambulatory Surgery Centers (ASCs), handling everything from patient scheduling and preoperative assessments to intraoperative documentation and postoperative follow-up. It integrates revenue cycle management, inventory tracking, and compliance tools to streamline ASC workflows and ensure regulatory adherence like MIPS and ASCQR. The software emphasizes surgical-specific features, such as block time optimization and real-time case tracking, reducing administrative burdens in high-volume surgical environments.

Pros

  • Highly specialized ASC features like perioperative charting and surgical inventory management
  • Seamless integration with anesthesia systems and billing platforms
  • Strong analytics for case utilization and revenue cycle performance

Cons

  • Steeper learning curve for non-surgical staff
  • Limited mobile app functionality compared to general EHRs
  • Custom pricing can be opaque without a demo

Best For

Mid-sized ASCs with multiple ORs seeking a surgery-focused EHR to optimize block time and compliance.

Pricing

Custom subscription pricing starting at around $500 per surgeon/month, scaled by facility size and modules.

Visit ORBITorbitsurgical.com
4
Provation MD logo

Provation MD

specialized

Advanced clinical documentation and workflow tool that enhances EHR efficiency in ASC procedures.

Overall Rating8.7/10
Features
9.4/10
Ease of Use
8.1/10
Value
7.9/10
Standout Feature

VoiceDictate with AI-driven structured reporting for procedure notes that auto-generate precise CPT and ICD codes

Provation MD is a cloud-based procedural documentation and EHR solution tailored for ambulatory surgery centers (ASCs), specializing in specialties like gastroenterology, pulmonology, and cardiology. It streamlines clinical workflows through customizable templates, voice recognition, and structured reporting that automates coding and billing. Designed to integrate seamlessly with major EHR systems, it enhances efficiency, compliance, and accuracy in high-volume procedural environments.

Pros

  • Advanced voice recognition for rapid, hands-free documentation
  • Automated coding and billing with high accuracy
  • Extensive customizable templates and integration capabilities

Cons

  • High subscription costs for smaller ASCs
  • Steep learning curve for non-specialty users
  • Limited breadth as a full-spectrum EHR outside procedures

Best For

ASCs focused on procedural specialties like GI and cardiology that prioritize fast, compliant documentation.

Pricing

Enterprise subscription model starting at ~$150/user/month, scaled by procedures and modules; custom quotes required.

Visit Provation MDprovationmedical.com
5
Waystar logo

Waystar

enterprise

Revenue cycle management solution that seamlessly integrates with ASC EHR systems for optimized billing and claims.

Overall Rating8.4/10
Features
9.1/10
Ease of Use
7.6/10
Value
8.2/10
Standout Feature

AI-powered Claim Guardian for real-time denial prevention and automated recovery

Waystar is a leading cloud-based revenue cycle management (RCM) platform designed for healthcare providers, including ambulatory surgery centers (ASCs), focusing on financial optimization rather than full clinical EHR functionality. It automates claims processing, patient eligibility verification, denial management, and payment collection while integrating with existing EHR systems. For ASCs, it streamlines billing workflows to improve cash flow and reduce administrative burdens.

Pros

  • Advanced AI-driven denial prediction and prevention
  • Seamless integrations with major EHRs like Epic and Cerner
  • Comprehensive analytics for revenue cycle insights

Cons

  • Limited native clinical documentation (RCM-focused, not full EHR)
  • Complex initial setup and training required
  • Pricing lacks transparency without a quote

Best For

Mid-sized ASCs prioritizing revenue cycle efficiency and billing automation over standalone clinical EHR capabilities.

Pricing

Custom enterprise pricing based on claim volume and modules; typically subscription model starting at several thousand dollars monthly for ASCs.

Visit Waystarwaystar.com
6
athenaOne logo

athenaOne

enterprise

Cloud-based EHR platform supporting ambulatory surgery centers with patient engagement and interoperability features.

Overall Rating8.4/10
Features
8.7/10
Ease of Use
8.0/10
Value
7.9/10
Standout Feature

AI-powered revenue cycle intelligence via the athenahealth network for real-time payer performance insights

athenaOne by athenahealth is a comprehensive cloud-based EHR and practice management platform tailored for ambulatory surgery centers (ASCs) and other outpatient facilities. It integrates clinical documentation, scheduling, billing, and patient engagement tools to streamline workflows and improve operational efficiency. The system emphasizes interoperability through its nationwide network, enabling seamless data exchange with payers and other providers.

Pros

  • Robust revenue cycle management with AI-driven claims optimization
  • Cloud-based accessibility and scalability for multi-location ASCs
  • Strong interoperability and population health analytics

Cons

  • High subscription costs that may strain smaller practices
  • Steep learning curve for advanced customization
  • Implementation can take longer than competitors

Best For

Mid-sized ASCs needing integrated EHR, billing, and payer connectivity without heavy on-premise infrastructure.

Pricing

Subscription model starting at $450-$700 per provider/month, plus one-time implementation fees of $10K+ and add-ons for advanced modules.

Visit athenaOneathenhealth.com
7
NextGen Office logo

NextGen Office

enterprise

Specialty EHR and practice management system adaptable for ASC workflows and regulatory compliance.

Overall Rating8.2/10
Features
8.7/10
Ease of Use
7.4/10
Value
7.9/10
Standout Feature

AI-powered revenue cycle management with predictive analytics for claims denial prevention

NextGen Office is a cloud-based EHR platform from NextGen Healthcare designed specifically for ambulatory surgery centers (ASCs) and specialty practices. It streamlines clinical workflows with features like customizable templates, scheduling, e-prescribing, and interoperability via HL7 and FHIR standards. The software excels in revenue cycle management, including automated billing and claims processing, helping ASCs optimize operations and compliance.

Pros

  • Robust interoperability and ONC certification for seamless data exchange
  • Advanced revenue cycle management with AI-driven claims optimization
  • Comprehensive ASC-specific templates and surgical workflow tools

Cons

  • Steep learning curve and complex initial setup
  • Higher-than-average implementation costs and timelines
  • Customer support response times can vary

Best For

Mid-sized ambulatory surgery centers focused on specialty procedures that need strong revenue cycle management and regulatory compliance tools.

Pricing

Subscription-based, typically $400-$700 per provider per month plus one-time implementation fees of $50K+ depending on practice size.

8
AdvancedMD logo

AdvancedMD

enterprise

All-in-one EHR, billing, and scheduling software designed for outpatient and surgery center practices.

Overall Rating8.4/10
Features
8.7/10
Ease of Use
8.2/10
Value
7.9/10
Standout Feature

Integrated revenue cycle management with automated claims scrubbing and denial management tailored for high-volume ASC billing.

AdvancedMD is a cloud-based EHR and practice management platform tailored for ambulatory surgery centers (ASCs) and specialty practices, offering integrated tools for scheduling, clinical documentation, billing, and revenue cycle management. It supports ASC-specific workflows like surgical scheduling, anesthesia tracking, and post-op follow-up, ensuring compliance with regulations such as HIPAA and MIPS. The system also includes patient engagement features like portals and telehealth integration for streamlined operations.

Pros

  • Comprehensive integration of EHR, PM, and RCM in one platform
  • Cloud-based with mobile access and strong customization for ASC workflows
  • Advanced analytics and reporting for operational insights

Cons

  • Higher pricing can be a barrier for smaller ASCs
  • Steep learning curve during initial setup and training
  • Customer support response times can vary

Best For

Mid-sized ambulatory surgery centers needing a scalable, all-in-one solution for surgical workflows and revenue optimization.

Pricing

Custom quotes based on practice size; starts at approximately $400-$700 per provider per month for core EHR + PM modules, with add-ons for advanced features.

Visit AdvancedMDadvancedmd.com
9
Kareo logo

Kareo

enterprise

EHR and billing platform offering simplicity and value for independent ambulatory surgery centers.

Overall Rating8.1/10
Features
7.9/10
Ease of Use
8.5/10
Value
7.8/10
Standout Feature

AI-powered revenue cycle management that automates claims scrubbing, denial prevention, and payment posting

Kareo is a cloud-based EHR and practice management platform designed for independent medical practices, including ambulatory surgery centers (ASCs), offering integrated clinical documentation, scheduling, billing, and revenue cycle management. It supports ASC workflows with patient intake, surgical scheduling, and compliance reporting, while emphasizing interoperability via standards like HL7 and FHIR. The platform aims to reduce administrative burdens and maximize reimbursements through automation and analytics.

Pros

  • Strong integration of EHR with revenue cycle management and billing
  • Intuitive, mobile-friendly interface suitable for busy ASC staff
  • Robust patient portal and telehealth capabilities

Cons

  • Limited specialized ASC features like advanced OR scheduling or implant tracking
  • Pricing can escalate with add-ons and per-claim fees
  • Some users report slower performance during peak usage

Best For

Small to mid-sized ASCs needing an affordable, all-in-one EHR with excellent billing integration and minimal setup.

Pricing

Starts at $144/provider/month for EHR + PM; billing services add 4-7% of collections; custom quotes for ASCs.

Visit Kareokareo.com
10
eClinicalWorks logo

eClinicalWorks

enterprise

Robust EHR solution with telehealth and analytics features suitable for ASC environments.

Overall Rating7.4/10
Features
8.2/10
Ease of Use
6.8/10
Value
7.0/10
Standout Feature

Healow patient engagement suite with AI-driven telehealth and mobile app access

eClinicalWorks is a cloud-based EHR and practice management platform designed for ambulatory surgery centers (ASCs) and outpatient practices, providing tools for patient charting, surgical scheduling, anesthesia documentation, and regulatory compliance. It integrates revenue cycle management, telehealth via Healow, and interoperability with other healthcare systems to streamline ASC workflows. The system supports MIPS reporting and population health analytics, making it suitable for mid-sized surgical facilities.

Pros

  • Comprehensive ASC-specific templates for surgery and anesthesia
  • Strong interoperability and telehealth integration
  • Robust revenue cycle management with analytics

Cons

  • Steep learning curve and cluttered interface
  • Customer support response times can be inconsistent
  • Implementation process is lengthy and complex

Best For

Mid-sized ASCs needing a scalable, all-in-one EHR with advanced billing and compliance features.

Pricing

Custom quote-based pricing, typically $499-$799 per provider per month plus implementation fees.

Visit eClinicalWorkseclinicalworks.com

Conclusion

The ranked tools highlight strong solutions for ambulatory surgery centers, with Amkai ASC360 leading as the top choice due to its tailored integration of scheduling, billing, and practice management. Surgical Information Systems (SIS) and ORBIT follow closely, offering robust perioperative and scheduling capabilities, respectively, each aligning with specific operational priorities.

Amkai ASC360 logo
Our Top Pick
Amkai ASC360

Don't miss the opportunity to explore Amkai ASC360—our top-ranked tool—to optimize ASC workflows and drive better patient and practice outcomes.