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Healthcare Medicine

Top 10 Best Acute Care Software of 2026

Discover the top 10 best acute care software for efficient patient care. Explore our guide to find your perfect tool – get started now!

Sarah Mitchell

Sarah Mitchell

Feb 11, 2026

10 tools comparedExpert reviewed
Independent evaluation · Unbiased commentary · Updated regularly
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In high-stakes acute care settings, robust software is indispensable for optimizing clinical workflows, enhancing patient outcomes, and streamlining operational efficiency. With options ranging from comprehensive EHR platforms to specialized AI-driven tools, selecting the right solution is key to meeting the dynamic demands of modern healthcare.

Quick Overview

  1. 1#1: Epic - Comprehensive EHR platform leading in acute care with advanced interoperability, analytics, and clinical workflows for hospitals.
  2. 2#2: Oracle Health - Integrated health IT suite including Millennium EHR for acute care management, population health, and operational efficiency.
  3. 3#3: MEDITECH Expanse - Web-based EHR designed for acute care hospitals offering scalable clinical and financial tools with AI enhancements.
  4. 4#4: Altera Sunrise - Robust acute care EHR supporting clinical documentation, order management, and revenue cycle in complex hospital environments.
  5. 5#5: Evident Thrive - Integrated EHR and RCM platform tailored for community acute care hospitals with strong usability and cost-effectiveness.
  6. 6#6: MEDHOST - Emergency department information system (EDIS) and acute care solutions for high-acuity patient throughput and compliance.
  7. 7#7: Philips Tasy - Unified EMR with seamless device integration for acute care monitoring, workflows, and patient safety.
  8. 8#8: GE HealthCare Centricity - Enterprise clinical information system supporting acute care imaging, diagnostics, and command center operations.
  9. 9#9: Optum Picis - Specialized perioperative and critical care software for surgical tracking and acute resource management.
  10. 10#10: Viz.ai - AI-driven platform for detecting and coordinating acute neurological events like stroke in hospital settings.

Tools were ranked based on clinical capabilities, interoperability, user-friendliness, and overall value, ensuring they address the unique needs of acute care environments from large hospitals to community health systems.

Comparison Table

Acute care software is vital for healthcare organizations, enhancing efficiency and patient outcomes. This comparison table delves into tools like Epic, Oracle Health, MEDITECH Expanse, Altera Sunrise, Evident Thrive, and more, offering key insights to guide software selection.

1Epic logo9.5/10

Comprehensive EHR platform leading in acute care with advanced interoperability, analytics, and clinical workflows for hospitals.

Features
9.8/10
Ease
7.2/10
Value
8.5/10

Integrated health IT suite including Millennium EHR for acute care management, population health, and operational efficiency.

Features
9.6/10
Ease
7.9/10
Value
8.4/10

Web-based EHR designed for acute care hospitals offering scalable clinical and financial tools with AI enhancements.

Features
9.1/10
Ease
7.8/10
Value
8.2/10

Robust acute care EHR supporting clinical documentation, order management, and revenue cycle in complex hospital environments.

Features
9.2/10
Ease
7.4/10
Value
8.1/10

Integrated EHR and RCM platform tailored for community acute care hospitals with strong usability and cost-effectiveness.

Features
6.5/10
Ease
7.2/10
Value
5.0/10
6MEDHOST logo8.1/10

Emergency department information system (EDIS) and acute care solutions for high-acuity patient throughput and compliance.

Features
8.4/10
Ease
7.7/10
Value
7.9/10

Unified EMR with seamless device integration for acute care monitoring, workflows, and patient safety.

Features
8.7/10
Ease
7.4/10
Value
7.9/10

Enterprise clinical information system supporting acute care imaging, diagnostics, and command center operations.

Features
8.6/10
Ease
7.4/10
Value
7.7/10

Specialized perioperative and critical care software for surgical tracking and acute resource management.

Features
9.0/10
Ease
7.2/10
Value
8.0/10
10Viz.ai logo8.7/10

AI-driven platform for detecting and coordinating acute neurological events like stroke in hospital settings.

Features
9.2/10
Ease
8.0/10
Value
7.8/10
1
Epic logo

Epic

enterprise

Comprehensive EHR platform leading in acute care with advanced interoperability, analytics, and clinical workflows for hospitals.

Overall Rating9.5/10
Features
9.8/10
Ease of Use
7.2/10
Value
8.5/10
Standout Feature

Epic's Care Everywhere interoperability network, allowing instant access to longitudinal patient data across unaffiliated organizations

Epic is a comprehensive electronic health record (EHR) system tailored for acute care settings, including hospitals, emergency departments, ICUs, and inpatient units. It streamlines clinical workflows with features like computerized physician order entry (CPOE), clinical decision support, medication management, and real-time patient monitoring. Epic's ecosystem supports interoperability across 250+ health systems, enabling secure data exchange for over 300 million patient records, making it the gold standard for large-scale acute care delivery.

Pros

  • Unparalleled depth in acute care modules for inpatient, ED, and perioperative workflows
  • Epic Galaxy network for nationwide interoperability and data sharing
  • Advanced analytics, AI-driven insights, and customizable reporting

Cons

  • Extremely high implementation costs and lengthy deployment (often 2-5 years)
  • Steep learning curve with complex interface requiring extensive training
  • Limited flexibility for small or mid-sized organizations due to scalability focus

Best For

Large hospital networks, academic medical centers, and integrated health systems needing enterprise-grade acute care EHR with robust scalability and interoperability.

Pricing

Custom enterprise licensing; implementation often exceeds $100M for large systems, plus annual fees of 2-4% of revenue and per-user costs.

Visit Epicepic.com
2
Oracle Health logo

Oracle Health

enterprise

Integrated health IT suite including Millennium EHR for acute care management, population health, and operational efficiency.

Overall Rating9.2/10
Features
9.6/10
Ease of Use
7.9/10
Value
8.4/10
Standout Feature

AI-powered Oracle Clinical Digital Assistant for real-time, voice-enabled clinical documentation and decision support

Oracle Health is a comprehensive electronic health record (EHR) platform designed for acute care settings like hospitals and emergency departments, offering end-to-end clinical workflows including documentation, order entry, medication management, and perioperative care. It leverages Oracle's cloud infrastructure and AI capabilities for real-time data analytics, interoperability via FHIR standards, and predictive insights to enhance patient outcomes. The solution, built on the legacy Cerner Millennium platform, supports high-volume inpatient environments with robust scalability for enterprise health systems.

Pros

  • Enterprise-grade scalability for large hospitals with seamless device integration
  • Advanced AI-driven clinical decision support and predictive analytics
  • Strong interoperability and compliance with healthcare standards like FHIR and HL7

Cons

  • Complex implementation process with long timelines and high costs
  • Steep learning curve for clinical staff due to extensive customization options
  • Premium pricing that may overwhelm smaller facilities

Best For

Large-scale hospital networks and academic medical centers needing robust, AI-enhanced acute care EHR with deep analytics.

Pricing

Custom enterprise licensing with implementation costs often exceeding $1M+ and annual subscriptions based on bed size/users; contact sales for quotes.

Visit Oracle Healthoracle.com/health
3
MEDITECH Expanse logo

MEDITECH Expanse

enterprise

Web-based EHR designed for acute care hospitals offering scalable clinical and financial tools with AI enhancements.

Overall Rating8.6/10
Features
9.1/10
Ease of Use
7.8/10
Value
8.2/10
Standout Feature

Expanse Platform's single desktop experience with embedded real-time analytics and AI tools directly in clinician workflows

MEDITECH Expanse is a web-based electronic health record (EHR) platform tailored for acute care environments like hospitals and health systems. It supports clinical workflows including documentation, order entry, medication management, and real-time decision support. The system emphasizes interoperability, population health analytics, and mobile accessibility to enhance patient care delivery and operational efficiency.

Pros

  • Robust interoperability with standards like FHIR for seamless data exchange
  • Advanced analytics and AI-driven insights for population health and predictive care
  • Fully web-based platform with mobile apps for anytime, anywhere access

Cons

  • Steep learning curve and extensive training required for full adoption
  • Lengthy and costly implementation process, often 12-24 months
  • Customizations can be rigid compared to more modular competitors

Best For

Medium to large acute care hospitals and health systems prioritizing integrated EHR with strong analytics and long-term scalability.

Pricing

Enterprise custom pricing based on facility size and modules; typically involves multi-million-dollar upfront implementation plus annual subscriptions per bed/user.

4
Altera Sunrise logo

Altera Sunrise

enterprise

Robust acute care EHR supporting clinical documentation, order management, and revenue cycle in complex hospital environments.

Overall Rating8.6/10
Features
9.2/10
Ease of Use
7.4/10
Value
8.1/10
Standout Feature

Integrated Clinical Command Center for real-time patient surveillance and predictive analytics across the acute care continuum

Altera Sunrise is a comprehensive electronic health record (EHR) platform tailored for acute care settings, including hospitals, emergency departments, and inpatient units. It streamlines clinical workflows with features like order entry, medication management, documentation, and real-time decision support. The system excels in interoperability, allowing seamless data exchange across enterprise health IT ecosystems while supporting high-volume, complex patient care.

Pros

  • Robust acute care functionality covering ER, inpatient, and perioperative workflows
  • High customizability with powerful configuration tools
  • Strong interoperability and integration with third-party systems

Cons

  • Steep learning curve and complex user interface
  • Lengthy and costly implementation process
  • Premium pricing that may strain smaller budgets

Best For

Large hospitals and health systems requiring a scalable, enterprise-grade EHR for high-acuity patient management.

Pricing

Custom enterprise pricing, typically starting at $500K+ annually based on bed size and modules, with implementation costs often exceeding $1M.

Visit Altera Sunrisealteradigitalhealth.com
5
Evident Thrive logo

Evident Thrive

enterprise

Integrated EHR and RCM platform tailored for community acute care hospitals with strong usability and cost-effectiveness.

Overall Rating5.8/10
Features
6.5/10
Ease of Use
7.2/10
Value
5.0/10
Standout Feature

Advanced automation for regulatory compliance like OASIS and HMM, streamlining post-acute documentation from acute discharges

Evident Thrive is a cloud-based EHR and practice management platform primarily built for home health, hospice, and post-acute care, offering tools for clinical documentation, scheduling, billing, and compliance. It includes mobile apps for field clinicians, telehealth integration, and automation features like OASIS assessment support. While strong in transitional care workflows, it lacks core acute care functionalities such as inpatient bed management, real-time hospital vitals monitoring, or surgical order sets, making it less ideal for traditional hospital acute care environments.

Pros

  • Modern cloud-based architecture with excellent mobile accessibility for clinicians
  • Strong compliance and billing automation tailored to post-acute transitions
  • Telehealth and voice documentation features enhance efficiency in field-based care

Cons

  • Not designed for core acute care needs like ICU monitoring or hospital order management
  • Limited scalability for high-volume inpatient acute care settings
  • Customization options insufficient for complex hospital workflows

Best For

Post-acute care providers or small acute facilities focused on care transitions and home-based follow-up rather than inpatient hospital operations.

Pricing

Custom enterprise pricing, typically subscription-based starting at $200-500 per user/month depending on modules and agency size; contact vendor for quote.

6
MEDHOST logo

MEDHOST

enterprise

Emergency department information system (EDIS) and acute care solutions for high-acuity patient throughput and compliance.

Overall Rating8.1/10
Features
8.4/10
Ease of Use
7.7/10
Value
7.9/10
Standout Feature

Acuity-based ED management with real-time patient boarding and throughput analytics

MEDHOST is a comprehensive EHR platform designed specifically for acute care settings, including emergency departments, inpatient units, and perioperative environments. It offers integrated modules for clinical documentation, order management, revenue cycle, and patient flow optimization to streamline hospital operations. With a focus on clinician efficiency and real-time data insights, MEDHOST supports high-acuity patient care while ensuring compliance with regulatory standards.

Pros

  • Robust ED-specific tools for patient tracking and throughput
  • Highly customizable workflows tailored to acute care needs
  • Strong integration with revenue cycle and billing systems

Cons

  • Steep learning curve and lengthy implementation
  • Higher pricing for smaller facilities
  • User interface feels somewhat dated compared to modern EHRs

Best For

Mid-sized hospitals with high-volume emergency departments needing specialized acute care workflows.

Pricing

Enterprise-level custom pricing; typically starts at $200+ per bed/month, requires vendor quote.

Visit MEDHOSTmedhost.com
7
Philips Tasy logo

Philips Tasy

enterprise

Unified EMR with seamless device integration for acute care monitoring, workflows, and patient safety.

Overall Rating8.2/10
Features
8.7/10
Ease of Use
7.4/10
Value
7.9/10
Standout Feature

Seamless, plug-and-play integration with Philips patient monitors, automatically populating real-time hemodynamic data into the patient's unified record.

Philips Tasy is a comprehensive electronic health record (EHR) and hospital information system (HIS) tailored for acute care settings, unifying clinical, administrative, and financial workflows across hospital departments. It provides real-time patient data access, clinical decision support, and seamless integration with medical devices for enhanced care coordination in high-acuity environments like ICUs and EDs. Tasy enables interdisciplinary teams to manage the entire patient journey from admission to discharge with a single, longitudinal record.

Pros

  • Robust integration with Philips monitoring devices for real-time vital signs and data flow
  • Comprehensive clinical decision support tools reducing errors and improving outcomes
  • Scalable architecture supporting large-scale hospital deployments

Cons

  • Steep learning curve and complex initial setup requiring extensive training
  • High implementation and customization costs
  • Limited flexibility for non-Philips device integrations compared to competitors

Best For

Large acute care hospitals with Philips monitoring infrastructure seeking a unified EHR for high-volume patient management.

Pricing

Enterprise-level custom pricing with significant upfront implementation fees (often $1M+), annual licensing, and maintenance costs based on bed size and modules.

8
GE HealthCare Centricity logo

GE HealthCare Centricity

enterprise

Enterprise clinical information system supporting acute care imaging, diagnostics, and command center operations.

Overall Rating8.1/10
Features
8.6/10
Ease of Use
7.4/10
Value
7.7/10
Standout Feature

Native integration with GE HealthCare's imaging portfolio for real-time, vendor-neutral access to radiology, cardiology, and enterprise-wide images

GE HealthCare Centricity is a comprehensive electronic health record (EHR) system tailored for acute care settings like hospitals and emergency departments, offering modules for clinical documentation, order management, medication administration, and perioperative workflows. It emphasizes interoperability with GE's imaging and diagnostic devices, enabling seamless data flow across enterprise systems. Centricity supports high-volume patient care with decision support tools and compliance features for regulatory standards.

Pros

  • Deep integration with GE imaging and devices for unified diagnostics
  • Scalable architecture suitable for large hospital networks
  • Robust clinical decision support and regulatory compliance tools

Cons

  • Steep learning curve and complex user interface
  • High upfront implementation and customization costs
  • Relatively slower adaptation to modern cloud-native features

Best For

Large acute care hospitals with existing GE equipment seeking reliable, imaging-integrated EHR for enterprise-scale operations.

Pricing

Custom enterprise pricing with implementation costs often exceeding $1M for mid-sized facilities, plus annual maintenance fees.

9
Optum Picis logo

Optum Picis

enterprise

Specialized perioperative and critical care software for surgical tracking and acute resource management.

Overall Rating8.3/10
Features
9.0/10
Ease of Use
7.2/10
Value
8.0/10
Standout Feature

Touch-enabled anesthesia information management system (AIMS) for seamless intra-operative documentation

Optum Picis is a comprehensive perioperative and critical care software suite tailored for acute care environments, including operating rooms, ICUs, and PACUs. It offers clinician-centric tools for anesthesia documentation, surgical scheduling, inventory management, and real-time patient monitoring to streamline workflows and enhance decision-making. The platform integrates with major EHRs and emphasizes touch-enabled interfaces for efficient intra-operative charting and compliance reporting.

Pros

  • Highly specialized perioperative and critical care modules with real-time data capture
  • Strong integration capabilities with EHRs like Epic and Cerner
  • Clinician-driven design reduces documentation time during procedures

Cons

  • Steep learning curve for non-technical clinical staff
  • Complex implementation process often requiring extensive customization
  • High ongoing maintenance and support costs

Best For

Large hospitals and ambulatory surgery centers handling high-volume acute care procedures.

Pricing

Enterprise-level custom pricing, typically $500K+ annually for mid-sized implementations including modules, support, and training.

10
Viz.ai logo

Viz.ai

specialized

AI-driven platform for detecting and coordinating acute neurological events like stroke in hospital settings.

Overall Rating8.7/10
Features
9.2/10
Ease of Use
8.0/10
Value
7.8/10
Standout Feature

Real-time AI-powered LVO detection from non-contrast CT scans with mobile stroke team alerts

Viz.ai is an AI-powered platform specializing in acute stroke care, using computer vision to analyze CT head scans in real-time for detecting large vessel occlusions (LVOs) and other stroke indicators. It automatically notifies stroke teams via mobile alerts, coordinates care workflows, and integrates with EHR and PACS systems to expedite triage and treatment. The solution has FDA clearance and is deployed in hundreds of hospitals to reduce door-to-needle times for thrombolysis and thrombectomy.

Pros

  • Ultra-fast AI detection with high sensitivity for LVOs, often under 2 minutes
  • Seamless mobile notifications and command center dashboard for team coordination
  • Proven clinical outcomes with reduced treatment times in real-world studies

Cons

  • Narrow focus primarily on neurovascular emergencies, less versatile for general acute care
  • Requires robust IT integration and high-quality imaging hardware
  • Enterprise pricing model can be costly for mid-sized or rural facilities

Best For

Large stroke centers and comprehensive hospitals prioritizing rapid neurovascular intervention workflows.

Pricing

Custom enterprise subscription, typically $100K–$500K+ annually based on bed count, scan volume, and modules.

Conclusion

The review of acute care software highlights a distinguished group, with Epic leading as the top choice, boasting a comprehensive EHR platform that excels in interoperability, analytics, and clinical workflows. Close behind are Oracle Health, offering an integrated suite for acute management and population health, and MEDITECH Expanse, a scalable web-based solution with AI enhancements—each providing robust options tailored to different institutional needs. Together, these tools redefine efficiency and care delivery in acute settings.

Epic logo
Our Top Pick
Epic

To unlock the full potential of acute care management, begin with Epic, a proven leader in driving seamless, effective clinical and operational outcomes.