Key Takeaways
- Globally, an estimated 287,000 women died from pregnancy- or childbirth-related causes in 2020, with 94% of these deaths occurring in low and lower-middle income countries
- In the United States, the maternal mortality rate increased to 32.9 deaths per 100,000 live births in 2021 from 23.8 in 2020, driven largely by cardiovascular conditions
- About 830 women die from preventable causes related to pregnancy and childbirth every day worldwide, equivalent to one woman every two minutes
- Breast cancer is the most common cancer in women worldwide, with 2.3 million new cases diagnosed in 2020 representing 11.7% of all cancer cases
- In the US, 297,790 new cases of female breast cancer were expected in 2023, accounting for 30% of all new female cancers
- Cervical cancer causes 342,000 deaths annually worldwide, primarily in low- and middle-income countries
- Depression affects 10% of pregnant women and 13% postpartum worldwide
- In the US, 1 in 5 women experience mental illness annually, compared to 1 in 10 men
- Postpartum depression occurs in 17.22% of new mothers globally per meta-analysis
- Cardiovascular disease is the leading cause of death in women globally, killing 17.9 million annually with 35% of total CVD deaths in women
- In the US, 1 in 3 women die from heart disease, higher than all cancers combined
- Women develop heart disease 7-10 years later than men but have higher mortality post-event
- Globally, 16% of women aged 30-49 are obese, rising to 42% in high-income countries
- Infertility affects 1 in 6 people worldwide, with 48 million women experiencing it
- Endometriosis affects 190 million women globally, causing chronic pelvic pain
Maternal and cancer deaths among women reveal stark global health disparities.
Cancer Statistics
- Breast cancer is the most common cancer in women worldwide, with 2.3 million new cases diagnosed in 2020 representing 11.7% of all cancer cases
- In the US, 297,790 new cases of female breast cancer were expected in 2023, accounting for 30% of all new female cancers
- Cervical cancer causes 342,000 deaths annually worldwide, primarily in low- and middle-income countries
- Ovarian cancer has a 5-year survival rate of 49% in the US, but only 18% when diagnosed at distant stage
- Globally, 604,000 women died from breast cancer in 2020, making it the fifth leading cause of cancer death
- In Europe, endometrial cancer incidence rates are projected to rise 21% by 2040 due to aging populations
- HPV causes 90% of cervical cancers, with vaccination preventing up to 90% of cases
- US women have a 12.9% lifetime risk of being diagnosed with breast cancer
- Colorectal cancer is the third most common cancer in women globally, with 870,000 new cases in 2020
- Lung cancer kills more women than breast cancer in the US, with 66,000 deaths expected in 2023
- Globally, 13% of cancers diagnosed in women are cervical
- In the UK, breast cancer survival rates reached 86% at 5 years for women diagnosed in 2010-11
- Uterine cancer incidence has increased 2% annually in US women under 50 since 2000
- 4,800 women die from cervical cancer yearly in the EU despite screening programs
- BRCA1 mutation carriers have 72% lifetime risk of breast cancer
- Globally, 90% of cervical cancer deaths occur in low- and middle-income countries
- In Australia, melanoma skin cancer is the third most common in women, with 4,500 cases in 2022
- Pancreatic cancer 5-year survival in women is 12.5% in the US
- 1 in 8 US women will develop invasive breast cancer in their lifetime
- Liver cancer rates in women are rising due to NAFLD, up 3% annually globally
- In India, oral cancer is common in women due to tobacco, with 86,000 cases in 2020
- Triple-negative breast cancer affects 15% of cases and is more aggressive in younger women
- Globally, 570,000 new uterine corpus cancer cases in 2020
Cancer Statistics Interpretation
Cardiovascular and Chronic Conditions
- Cardiovascular disease is the leading cause of death in women globally, killing 17.9 million annually with 35% of total CVD deaths in women
- In the US, 1 in 3 women die from heart disease, higher than all cancers combined
- Women develop heart disease 7-10 years later than men but have higher mortality post-event
- Diabetes affects 422 million adults globally, with women comprising 44% and facing higher complication risks
- Osteoporosis causes 9 million fractures yearly worldwide, 75% in women post-menopause
- In Europe, 53% of women over 50 have osteopenia, precursor to osteoporosis
- Rheumatoid arthritis affects 1.3% of US women vs 0.6% men
- Chronic kidney disease stage 3+ affects 15% of US women over 65
- Autoimmune diseases strike women 6-10 times more than men
- In the UK, 1 in 5 women over 50 have osteoporosis
- Stroke kills more women than men annually in the US
- Hypothyroidism affects 5% of women vs 1% men worldwide
- PCOS affects 6-12% of women of reproductive age, leading to metabolic syndrome in 40%
- Multiple sclerosis is 2-3 times more common in women
- In Australia, 80% of hip fractures occur in women, costing $1B annually
- Lupus affects 9 times more women than men
- Endometriosis impacts 10% of reproductive-age women, 190 million globally
- Gallbladder disease hospitalization rates are 62% higher in women
- Fibromyalgia prevalence is 2-4% in women vs 0.5% in men
- In Canada, 23% of women have hypertension vs 25% men, but women have poorer control
- Alzheimer's disease affects 2/3 of patients who are women in the US
- Migraine affects 18% of US women vs 6% men annually
- Interstitial cystitis impacts 3-8% of women
Cardiovascular and Chronic Conditions Interpretation
Maternal Health
- Globally, an estimated 287,000 women died from pregnancy- or childbirth-related causes in 2020, with 94% of these deaths occurring in low and lower-middle income countries
- In the United States, the maternal mortality rate increased to 32.9 deaths per 100,000 live births in 2021 from 23.8 in 2020, driven largely by cardiovascular conditions
- About 830 women die from preventable causes related to pregnancy and childbirth every day worldwide, equivalent to one woman every two minutes
- In sub-Saharan Africa, the maternal mortality ratio is 533 deaths per 100,000 live births, the highest in the world as of 2020 data
- Postpartum hemorrhage accounts for 27% of maternal deaths globally, making it the leading direct cause of maternal mortality
- In the US, Black women are 3-4 times more likely to die from pregnancy-related causes than white women, with a rate of 69.9 per 100,000 live births in 2021
- Hypertensive disorders contribute to 14% of global maternal deaths, affecting around 10% of pregnancies worldwide
- Only 49% of women in low-income countries have access to skilled birth attendants during delivery as of 2023 estimates
- Preterm birth complications are the leading cause of death in children under 5, but also contribute significantly to maternal morbidity, affecting 14.8 million women annually
- In 2022, the US saw 1,205 maternal deaths, with 80% deemed preventable by experts
- Sepsis accounts for 11% of maternal deaths worldwide, often due to unclean delivery practices
- Adolescent girls aged 10-14 face 20 times higher risk of death during pregnancy than women aged 20-24 in low-income regions
- In India, maternal mortality ratio stood at 97 per 100,000 live births in 2018-20, down from 130 in 2014-16
- Unsafe abortion causes 13% of maternal deaths globally, resulting in 47,000 deaths annually
- In the UK, 13 women per 100,000 maternities died in 2019-21, with Black women 3.67 times more likely than white women
- Anemia affects 40% of pregnant women worldwide, increasing risks of maternal and fetal mortality
- In low-income countries, 65% of women receive no or inadequate antenatal care
- Eclampsia contributes to 14% of maternal deaths, preventable with magnesium sulfate
- In Brazil, maternal mortality rate was 59.7 per 100,000 live births in 2020, with COVID-19 exacerbating rates
- 99% of all maternal deaths occur in developing regions
- In the US, drug overdose rates among pregnant women rose 94% from 2017 to 2021
- Obstructed labor causes 8% of maternal deaths globally
- In Ethiopia, maternal mortality ratio decreased to 267 per 100,000 live births by 2020 from 871 in 2000
- Cardiovascular diseases account for 33.4% of pregnancy-related deaths in the US in 2021
- Only 75% of births in low-income countries are attended by skilled health personnel as of 2023
- Indirect causes like HIV and malaria contribute to 27.5% of maternal deaths
- In Australia, Indigenous women have a maternal mortality rate 2.4 times higher than non-Indigenous women
- Severe maternal morbidity affects 50,000 women annually in the US
- Globally, 303,000 women died from pregnancy-related causes in 2015, with slow progress since
- In Nigeria, maternal mortality ratio is 814 per 100,000 live births, among the highest globally
Maternal Health Interpretation
Mental Health
- Depression affects 10% of pregnant women and 13% postpartum worldwide
- In the US, 1 in 5 women experience mental illness annually, compared to 1 in 10 men
- Postpartum depression occurs in 17.22% of new mothers globally per meta-analysis
- Anxiety disorders affect 23.4% of US women versus 14.3% of men lifetime prevalence
- 60% of women with perinatal mental health conditions receive no treatment
- In the UK, 20% of women experience depression in their lifetime, double the rate in men
- Eating disorders have highest mortality rate among psychiatric disorders, 5-10% in women with anorexia
- 1 in 3 women worldwide experience gender-based violence, linked to higher PTSD rates
- Perimenopausal women have 2-4 times higher depression risk
- In Australia, 42% of women aged 16-85 have experienced depression
- Bipolar disorder affects women more severely during reproductive years due to hormonal changes
- 80% of women with postpartum psychosis develop it within 2 weeks of delivery
- US women are twice as likely as men to experience major depression, 10.5% vs 5.5% past year
- Premenstrual dysphoric disorder affects 3-8% of women of reproductive age
- Suicide rates in pregnant/postpartum women are 7 times higher in those with depression
- In Canada, 25% of women experience mood disorders over lifetime
- Borderline personality disorder is diagnosed 75% more in women
- 1 in 6 US women take antidepressants, higher than men
- Perinatal anxiety affects 15-20% of pregnancies, often undiagnosed
- Globally, 10% of women experience depression during pregnancy
- Women with PCOS have 3-5 times higher depression risk
- In Japan, 11.4% of postpartum women have depression
- PTSD prevalence in women is 8% lifetime vs 4% in men
- Menopause increases anxiety risk by 2-fold
- 50% of women with schizophrenia experience postpartum relapse
Mental Health Interpretation
Reproductive Health
- Globally, 16% of women aged 30-49 are obese, rising to 42% in high-income countries
- Infertility affects 1 in 6 people worldwide, with 48 million women experiencing it
- Endometriosis affects 190 million women globally, causing chronic pelvic pain
- 80 million women in developing countries have unmet need for family planning
- Globally, 214 million women have an unmet need for contraception
- PCOS impacts 116 million women worldwide
- 45% of women aged 15-49 in low-income countries use modern contraception
- Female genital mutilation affects 200 million women and girls alive today
- In the US, 12% of women aged 15-44 have impaired fecundity
- Globally, 1 in 4 pregnancies end in abortion, 73 million annually
- Uterine fibroids affect up to 80% of women by age 50
- Sexually transmitted infections like chlamydia affect 129 million women annually
- In Europe, 25% of women aged 40-44 are childless, up from 18% in 2000
- Pelvic floor disorders affect 24% of US women
- Globally, 23 million unsafe abortions occur yearly, mostly in developing countries
- 10-15% of women experience recurrent miscarriage
- In sub-Saharan Africa, 24% of women have no access to contraception
- Ovarian cysts occur in 8% of premenopausal women
- Globally, 300 million women use oral contraceptives
- Adenomyosis affects 20-35% of women
- In the US, 11% of reproductive-age women have endometriosis symptoms
Reproductive Health Interpretation
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