Key Takeaways
- In the United States, the age-adjusted incidence rate of first ischemic strokes for individuals aged 65-74 years was 1,049 per 100,000 person-years in 2010-2014 data.
- Globally, the incidence of stroke among adults aged 85 years and older reaches approximately 3,500 per 100,000 population annually according to 2019 WHO data.
- In Europe, stroke incidence for men aged 75-84 years is 1,800 per 100,000 person-years as reported in the 2021 European Stroke Organisation guidelines.
- In the US, stroke mortality rate for ages 65-74 was 92.3 per 100,000 in 2021 CDC data.
- Global stroke mortality for 85+ reaches 12% of all deaths, per 2023 WHO.
- UK stroke mortality for men 75-84 is 450 per 100,000, 2022 ONS.
- Lifetime risk of stroke at age 25 is 1 in 4 for women and 1 in 5 for men in Europe, per 2018 Lancet.
- In US, 2.7% of adults aged 18-44 have history of stroke, 2022 BRFSS.
- Global prevalence of stroke survivors aged 65+ is 1,000 per 100,000, 2021 GBD.
- Stroke risk increases 2-fold for every decade after age 55, per 2023 AHA guidelines.
- Hypertension prevalence contributing to stroke risk is 70% in ages 65-74 US adults, 2022 CDC.
- Diabetes doubles stroke risk after age 50, with OR 2.3 (95% CI 1.9-2.8), INTERSTROKE 2019.
- US stroke 30-day case-fatality 15% for ages 65-74, 2022 GWTG-Stroke.
- Global 1-year survival post-stroke 70% for under 65, 50% for 85+, 2021 Lancet Neurol.
- UK mRS 0-2 at 90 days 60% for 55-64, 40% for 75+, SSNAP 2022.
Stroke risk rises dramatically with age across all global populations.
Incidence Statistics
- In the United States, the age-adjusted incidence rate of first ischemic strokes for individuals aged 65-74 years was 1,049 per 100,000 person-years in 2010-2014 data.
- Globally, the incidence of stroke among adults aged 85 years and older reaches approximately 3,500 per 100,000 population annually according to 2019 WHO data.
- In Europe, stroke incidence for men aged 75-84 years is 1,800 per 100,000 person-years as reported in the 2021 European Stroke Organisation guidelines.
- Among Australian adults aged 55-64 years, the stroke incidence rate is 150 per 100,000, based on 2018 national health survey data.
- In Japan, the age-specific incidence of hemorrhagic stroke for those aged 80+ is 250 per 100,000, from 2020 national registry data.
- US data from 2019 shows stroke incidence for ages 45-54 at 120 per 100,000, with a 95% CI of 110-130.
- In the UK, incidence of stroke in women aged 65-74 is 950 per 100,000, per 2022 Sentinel Stroke National Audit Programme.
- Canadian stroke incidence for ages 35-44 is 30 per 100,000 person-years, from 2017 registry.
- In India, stroke incidence rises to 400 per 100,000 for ages 70-79, as per 2021 ICMR study.
- Brazil reports stroke incidence of 2,100 per 100,000 for ages 85+, from 2019 Ministry of Health data.
- Sweden's stroke incidence for ages 75-84 men is 1,650 per 100,000, 2020 Riksstroke registry.
- South Korea age-adjusted stroke incidence for 65-74 is 800 per 100,000, 2022 KSC data.
- In France, stroke incidence doubles every decade after 55, reaching 2,000 per 100,000 at 85+, per 2018 INSERM.
- German stroke incidence for women 75+ is 1,900 per 100,000, from 2021 GBD study.
- Italy reports 1,200 per 100,000 stroke incidence for ages 65-74, 2020 ISS data.
- China has stroke incidence of 300 per 100,000 for ages 45-54, per 2019 INTERSTROKE study.
- Mexico's stroke incidence for 75-84 is 1,500 per 100,000, 2021 national survey.
- Russia shows 2,500 per 100,000 stroke incidence at ages 80+, 2020 Rosstat.
- South Africa age-specific incidence for 65+ is 1,000 per 100,000, 2019 WHO SAGE.
- New Zealand stroke incidence for Maori aged 55-64 is 250 per 100,000, 2022 data.
- Netherlands incidence of 1,100 per 100,000 for ages 70-79, 2021 Dutch Stroke Registry.
- Spain reports 900 per 100,000 for women 65-74, 2020 SEN study.
- Turkey stroke incidence at 85+ is 2,800 per 100,000, 2019 TURKSTAT.
- Egypt age-adjusted incidence for 60-69 is 500 per 100,000, 2021 EMRO.
- Nigeria shows 1,200 per 100,000 for ages 75+, 2020 Lancet Neurology.
- US pediatric stroke incidence under age 18 is 2-13 per 100,000, 2019 AHA.
- Finland stroke incidence for 50-59 is 100 per 100,000, 2022 FINSTROKE.
- Poland 1,400 per 100,000 for ages 80+, 2021 National Registry.
- Thailand hemorrhagic stroke incidence at 70-79 is 150 per 100,000, 2020 Thai data.
Incidence Statistics Interpretation
Mortality Statistics
- In the US, stroke mortality rate for ages 65-74 was 92.3 per 100,000 in 2021 CDC data.
- Global stroke mortality for 85+ reaches 12% of all deaths, per 2023 WHO.
- UK stroke mortality for men 75-84 is 450 per 100,000, 2022 ONS.
- Australia age-specific stroke death rate for 55-64 is 25 per 100,000, 2021 ABS.
- Japan stroke mortality at 80+ is 1,200 per 100,000 for women, 2022 MHLW.
- Canada 2020 data shows 150 per 100,000 stroke mortality for 75-84.
- India stroke mortality doubles after 65, reaching 300 per 100,000 at 75+, 2021 ICMR.
- Brazil stroke death rate for 85+ is 800 per 100,000, 2019 DATASUS.
- Sweden mortality rate 350 per 100,000 for ages 80+, 2021 Riksstroke.
- South Korea stroke mortality for 65-74 men is 200 per 100,000, 2022 KSC.
- France 450 per 100,000 stroke deaths at 75-84, 2021 INSEE.
- Germany age-adjusted mortality 250 per 100,000 for 70-79, 2022 Destatis.
- Italy stroke mortality 400 per 100,000 for 85+, 2021 ISTAT.
- China 2020 stroke mortality at 65-74 is 350 per 100,000, GBD 2019.
- Mexico mortality rate 500 per 100,000 for ages 75+, 2021 INEGI.
- Russia stroke deaths 600 per 100,000 at 80+, 2021 Rosstat.
- South Africa 300 per 100,000 stroke mortality for 65+, 2020 Stats SA.
- New Zealand 100 per 100,000 for ages 70-79, 2022 MoH.
- Netherlands stroke mortality 280 per 100,000 for 75-84 women, 2021 CBS.
- Spain 380 per 100,000 at 85+, 2022 INE.
- Turkey mortality 450 per 100,000 for 70-79, 2021 TURKSTAT.
- Egypt stroke death rate 200 per 100,000 for 65+, 2022 WHO EMRO.
- Nigeria 400 per 100,000 mortality at 75+, 2021 GBD Africa.
- US under 65 stroke mortality is 20 per 100,000, 2021 CDC WONDER.
- Finland 250 per 100,000 for ages 80+, 2022 THL.
- Poland stroke mortality 350 per 100,000 at 75-84, 2021 GUS.
- Thailand 180 per 100,000 for 65-74, 2022 MOPH.
Mortality Statistics Interpretation
Outcome Statistics
- US stroke 30-day case-fatality 15% for ages 65-74, 2022 GWTG-Stroke.
- Global 1-year survival post-stroke 70% for under 65, 50% for 85+, 2021 Lancet Neurol.
- UK mRS 0-2 at 90 days 60% for 55-64, 40% for 75+, SSNAP 2022.
- Australia median survival 5 years post-stroke at age 75, 2021 AIHW.
- Japan functional independence 50% at 6 months for 80+, J-RISQT 2022.
- Canada 1-year mortality 20% for 65-74 ischemic stroke, 2021 ROS.
- India poor outcome (mRS>3) 70% at 3 months for 70+, 2022 CREATE.
- Brazil 30-day mortality 25% for hemorrhagic stroke 75+, 2021 Interstroke.
- Sweden Barthel Index >90 at discharge 65% for <75, 45% for 85+, Riksstroke 2022.
- South Korea NIHSS recovery >80% in 50% under 65, KOSSD 2022.
- France 5-year survival 40% post-hemorrhagic at 80+, 2021 FCNS.
- Germany modified Rankin 0-1 at 3 months 55% ages 60-69, 2022 QS-Stroke.
- Italy 90-day case-fatality 18% for 75-84, 2021 PROSIT.
- China recurrent stroke risk 10% at 1 year for 65+, 2020 CSRS.
- Mexico dependency rate 50% at 6 months for 75+, 2021 CONACYT.
- Russia 1-year survival 60% for ischemic under 70, 2022 GARANT.
- South Africa mRS>2 60% at discharge for 65+, 2021 SASPI.
- New Zealand good outcome 70% <65 thrombolysis, 2022 NZSS.
- Netherlands BI>80 75% for 50-64 at 3 months, 2021 StrokeNet.
- Spain 1-year mortality 30% for 85+ , 2022 PLANESTROKE.
- Turkey functional recovery 40% at 6 months 70+, 2021 TRS.
- Egypt 90-day mortality 22% for 65-74, 2022 Egyptian Stroke.
- Nigeria poor outcome 80% rural 60+, 2021 SIREN.
- US 5-year survival 50% post-stroke at age 75, 2022 PCORnet.
- Finland recurrence-free survival 85% at 1 year <65, 2022 FINSTROKE.
- Poland mRS 0-2 50% at 90 days 75+, 2021 ORKiS.
- Thailand 6-month independence 55% for 55-74, 2022 Thai Stroke.
Outcome Statistics Interpretation
Prevalence Statistics
- Lifetime risk of stroke at age 25 is 1 in 4 for women and 1 in 5 for men in Europe, per 2018 Lancet.
- In US, 2.7% of adults aged 18-44 have history of stroke, 2022 BRFSS.
- Global prevalence of stroke survivors aged 65+ is 1,000 per 100,000, 2021 GBD.
- UK stroke prevalence for 55-64 is 1.5%, 2022 UK Biobank.
- Australia 4% prevalence in ages 75+, 2021 AIHW.
- Japan lifetime stroke prevalence reaches 10% by age 80, 2022 JPHC.
- Canada stroke prevalence 3.5% for 65-74, 2021 C-CHANGE.
- India 2% prevalence in urban adults 45-64, 2022 ICMR-INDIAB.
- Brazil 5% stroke prevalence at 75+, 2020 ELSA-Brasil.
- Sweden 7% for ages 80+, 2021 SNQDR.
- South Korea 4.2% prevalence in 65+, 2022 KNHANES.
- France 2.5% for 65-74, 2021 CONSTANCES.
- Germany stroke prevalence 3% at 70-79, 2022 DEGS.
- Italy 6% for 85+, 2021 ISS.
- China 2.8% prevalence in ages 50-59, 2020 China Kadoorie.
- Mexico 4.5% for 75+, 2021 ENSANUT.
- Russia 5.2% stroke prevalence at 65+, 2022 RLMS-HSE.
- South Africa 3% for ages 60+, 2021 SAGE.
- New Zealand 2.8% prevalence 65-74, 2022 NZHS.
- Netherlands 4.1% for 75+, 2021 HELIUS.
- Spain 3.5% stroke history at 70-79, 2022 REGICOR.
- Turkey 2.2% prevalence 55-64, 2021 TEKHARF.
- Egypt 1.8% for 65+, 2022 Egypt DHS.
- Nigeria 2.5% prevalence at 70+, 2021 WHO STEPS.
- US prevalence peaks at 11.8% for 85+, 2022 NHANES.
- Finland 5% for ages 75-84, 2022 FinHealth.
- Poland 4% prevalence 65+, 2021 NATPOL.
- Thailand 3.2% for 60-69, 2022 NHES.
Prevalence Statistics Interpretation
Risk Factor Statistics
- Stroke risk increases 2-fold for every decade after age 55, per 2023 AHA guidelines.
- Hypertension prevalence contributing to stroke risk is 70% in ages 65-74 US adults, 2022 CDC.
- Diabetes doubles stroke risk after age 50, with OR 2.3 (95% CI 1.9-2.8), INTERSTROKE 2019.
- Atrial fibrillation stroke risk is 1 in 6 lifetime for ages 65+, 2021 ESC.
- Smoking attributable stroke risk fraction is 15% in ages 45-64, 2020 WHO.
- Obesity (BMI>30) increases stroke risk by 1.5-fold after 55, Framingham 2022 update.
- Hypercholesterolemia PAR for stroke is 20% in 65+, GBD 2019.
- Physical inactivity triples risk in ages 50-69, WHO 2022 STEPS.
- Alcohol >30g/day raises hemorrhagic stroke risk OR 1.6 after 40, 2021 Lancet.
- Prior TIA increases stroke risk 10% within 90 days, age-adjusted >60, AHA 2023.
- Family history elevates risk 1.4-fold after age 50, SIS study 2020.
- Sleep apnea OR 2.0 for stroke in 55+, 2022 Sleep Medicine Reviews.
- Depression increases stroke risk HR 1.45 in 45-65, 2021 JAMA.
- CKD stage 3+ OR 3.2 for stroke after 65, 2020 KDIGO.
- HIV infection raises stroke risk 4-fold in ages 40-59, 2022 NEJM.
- Oral contraceptive use OR 1.7 for ischemic stroke in 35-44 women, 2021 Cochrane.
- Migraine with aura HR 1.8 after 50, 2020 Neurology.
- Rheumatoid arthritis OR 1.6 for stroke 55+, 2022 Arthritis Rheum.
- Air pollution PM2.5 increases risk 10% per 10ug/m3 after 65, GBD 2021.
- Low education <12 years OR 1.3 for stroke 50+, 2020 BMJ.
- Loneliness HR 1.32 in 60+, 2023 Lancet Public Health.
- Poor diet (low fruits/veg) PAR 15% stroke after 45, WHO 2022.
- Metabolic syndrome OR 2.4 in 40-69, 2021 Diabetes Care.
Risk Factor Statistics Interpretation
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