Key Takeaways
- Approximately 18,000 new cases of spinal cord injury (SCI) are reported annually in the United States
- The prevalence of spinal cord injury in the US is estimated at 316,000 individuals living with SCI as of 2023
- Globally, between 250,000 and 500,000 people suffer a spinal cord injury each year according to WHO estimates
- Vehicle crashes account for 38% of new SCI cases in the US
- Falls are the leading cause of SCI in individuals over 65, comprising 32% of cases
- Violence-related SCI, primarily gunshot wounds, accounts for 15% of new cases in the US
- 72% of new SCI cases in the US are male
- Average age at injury for males is 43 years, for females 44 years in US
- 80.7% of SCI cases are Caucasian, 13.8% Black, 4.8% Hispanic in US
- First year after SCI discharge, 50% require rehospitalization
- Average length of stay in acute care for SCI is 19 days in US model systems
- Inpatient rehabilitation length averages 38 days for traumatic SCI
- Life expectancy for complete tetraplegia is 88.2% at 1 year post-injury
- 40-year survival rate for SCI injured at age 20 is 55% for motor complete
- Suicide rate among SCI is 5 times higher than general population
Spinal cord injury affects thousands annually, causing profound lifelong consequences.
Causes
- Vehicle crashes account for 38% of new SCI cases in the US
- Falls are the leading cause of SCI in individuals over 65, comprising 32% of cases
- Violence-related SCI, primarily gunshot wounds, accounts for 15% of new cases in the US
- Sports and recreation injuries cause 8% of SCI, with diving being prominent
- Motorcycle crashes contribute to 21% of vehicle-related SCI incidents
- Pedestrian incidents account for 4% of traumatic SCI causes in the US
- In low-income countries, road traffic injuries cause 40-50% of traumatic SCI
- Iatrogenic causes like surgical complications represent 3.4% of non-traumatic SCI
- Tumors account for 7.3% of non-traumatic SCI etiologies in the US
- Vascular insults such as ischemia cause 5% of non-traumatic SCI cases
- Infections leading to SCI comprise 4.1% of non-traumatic cases
- Degenerative diseases contribute to 26% of non-traumatic SCI in the US
- Alcohol involvement is noted in 25% of traumatic SCI cases at admission
- All-terrain vehicle crashes cause 2% of SCI but rising trend
- Gunshot wounds to the spine are 13.5% of violence-related SCI
- Stabbing incidents account for 1.5% of traumatic SCI causes
- Equestrian activities cause 1% of sports-related SCI
- American football contributes to 0.5% of annual SCI cases in young males
- Surfing accidents lead to cervical SCI in 2.3 per million surfers annually
- Skiing/snowboarding injuries account for 15% of winter sports SCI
Causes Interpretation
Demographics
- 72% of new SCI cases in the US are male
- Average age at injury for males is 43 years, for females 44 years in US
- 80.7% of SCI cases are Caucasian, 13.8% Black, 4.8% Hispanic in US
- Cervical injuries (C1-C8) comprise 56% of all SCI levels
- Thoracic injuries (T1-T12) account for 34% of SCI neurological levels
- Lumbar/Sacral injuries make up 10% of SCI cases
- 42% of SCI occur in age group 16-30 years in the US
- Females represent 28% of the SCI population with higher fall-related injuries
- Non-Hispanic Black individuals have higher violence-related SCI rates at 25%
- 21% of SCI cases are in individuals over 60 years old
- Pediatric SCI (0-14 years) is 3.1% of total new cases
- Veterans with SCI are predominantly male (97%) and average age 57 at model system discharge
- 50.2% of new SCI are tetraplegia, 48.4% paraplegia in US
- Incomplete tetraplegia is the most common at 25.5% of cases
- C5 neurological level is the most frequent at 13.2%
- Urban residents account for 70% of SCI admissions in US model systems
- 15% of SCI individuals are employed pre-injury vs post-injury rates
- Educational attainment: 50% have high school or less pre-SCI
- Married individuals pre-SCI: 29% males, 37% females
Demographics Interpretation
Epidemiology
- Approximately 18,000 new cases of spinal cord injury (SCI) are reported annually in the United States
- The prevalence of spinal cord injury in the US is estimated at 316,000 individuals living with SCI as of 2023
- Globally, between 250,000 and 500,000 people suffer a spinal cord injury each year according to WHO estimates
- In Europe, the annual incidence rate of traumatic SCI is about 10-16 per million population
- Lifetime prevalence of SCI in Canada is approximately 1,850 per million population
- In Australia, around 400 new cases of SCI occur annually with a prevalence of over 12,000
- The incidence of SCI in low- and middle-income countries is estimated at 13-52 per million due to road traffic crashes
- In the US, the average age at injury for SCI has increased to 43 years from previous decades
- Non-traumatic SCI accounts for about 30% of all SCI cases in the US
- Pediatric SCI incidence in the US is approximately 1,200 new cases per year under age 15
- In the UK, SCI incidence is 13 per million population annually
- Geriatric SCI (over 65) cases have risen to 22% of new injuries in the US
- Global burden of SCI leads to 9,000 to 40,000 deaths annually from related causes
- In India, estimated annual SCI incidence is 20,000-25,000 cases
- US military veterans represent about 4% of the SCI population with 33,000 cases
- Incidence of complete SCI tetraplegia is 44% of new US cases
- Incomplete SCI paraplegia constitutes 35.3% of new traumatic SCI in the US
- In Brazil, SCI incidence rate is 18.5 per million population per year
- Lifetime cost of care for a 25-year-old with SCI in the US exceeds $5 million
- SCI prevalence in the US male population is 78% of total cases
Epidemiology Interpretation
Outcomes
- Life expectancy for complete tetraplegia is 88.2% at 1 year post-injury
- 40-year survival rate for SCI injured at age 20 is 55% for motor complete
- Suicide rate among SCI is 5 times higher than general population
- Employment rate 1 year post-injury is 34% for SCI vs 50% pre-injury
- 30% of SCI individuals live independently post-rehab
- Depression prevalence in chronic SCI is 27-48%
- Pressure sores recur in 20% annually despite prevention
- UTI incidence is 2.5 episodes per year per SCI individual
- 25% of SCI deaths are due to pneumonia/sepsis in first 20 years
- Divorce rate post-SCI is 48% higher than general population
- Community participation: 60% report dissatisfaction with social integration
- Pain interferes with daily activities in 53% of chronic SCI
- Spasticity affects 67% of traumatic SCI long-term
- Heterotopic ossification occurs in 20-30% of SCI patients
- Osteoporosis leads to 340 fractures per 100,000 SCI person-years
- Sexual dysfunction: 50-75% of males post-SCI experience erectile issues
- Fertility preservation success: 40% achieve fatherhood post-SCI with assistance
- Median household income post-SCI drops to $30,000 from $50,000 pre-injury
- Life satisfaction reported by 65% of long-term SCI survivors
- 15% of SCI individuals require lifelong mechanical ventilation
- Autonomic dysreflexia occurs in 48-90% of tetraplegics above T6
Outcomes Interpretation
Treatment
- First year after SCI discharge, 50% require rehospitalization
- Average length of stay in acute care for SCI is 19 days in US model systems
- Inpatient rehabilitation length averages 38 days for traumatic SCI
- 78% of SCI patients receive rehab services post-acute care
- Pressure ulcers affect 26% of SCI individuals within first year post-injury
- Surgical intervention is performed in 64% of cervical SCI cases
- Methylprednisolone use in acute SCI has decreased to less than 30% due to evidence
- Functional electrical stimulation improves motor scores by 10-20% in rehab
- Robotic exoskeleton training leads to 5-10m increase in walking distance
- Annual cost of first-year care for tetraplegia is $1.17 million (high tetraplegia)
- Lifetime healthcare costs for paraplegia average $2.5 million
- 95% of ventilator-dependent high tetraplegics survive first year with treatment
- Bladder management: 70% use intermittent catheterization post-rehab
- Bowel programs are required by 97% of SCI individuals long-term
- Antispastic medications used by 38% at rehab discharge
- Pain management: Neuropathic pain in 65% of chronic SCI patients
- Stem cell trials show 20-30% motor improvement in incomplete SCI phase II
- Epidural stimulation enables voluntary control in 3/8 motor complete cases
- Occupational therapy participation: 90% in first year rehab
- Physical therapy averages 1.5 hours/day in inpatient rehab
Treatment Interpretation
Sources & References
- Reference 1NSCISCnscisc.uab.eduVisit source
- Reference 2WHOwho.intVisit source
- Reference 3PUBMEDpubmed.ncbi.nlm.nih.govVisit source
- Reference 4RICKHANSENINSTITUTErickhanseninstitute.orgVisit source
- Reference 5NCDSncds.org.auVisit source
- Reference 6NCBIncbi.nlm.nih.govVisit source
- Reference 7SPINALspinal.co.ukVisit source
- Reference 8CDCcdc.govVisit source
- Reference 9CHRISTOPHERREEVEchristopherreeve.orgVisit source
- Reference 10SPINALCORDspinalcord.comVisit source






