GITNUXREPORT 2026

South Africa Aids Statistics

South Africa has the world's highest HIV rates but is making strong treatment progress.

Rajesh Patel

Rajesh Patel

Team Lead & Senior Researcher with over 15 years of experience in market research and data analytics.

First published: Feb 13, 2026

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Key Statistics

Statistic 1

New HIV infections in South Africa totaled 150,000 in 2022, down 44% since 2010.

Statistic 2

Annual HIV incidence rate among adults 15-49 was 0.73% in South Africa in 2022.

Statistic 3

72,000 new HIV infections occurred among adolescent girls and young women aged 15-24 in 2022.

Statistic 4

KwaZulu-Natal saw 28,500 new HIV infections in 2022, the highest provincially.

Statistic 5

Gauteng recorded 32,000 new HIV cases in adults in 2022.

Statistic 6

Incidence among young women 15-24 was 4.6% annually in high-prevalence areas in 2022.

Statistic 7

New infections among MSM were estimated at 12,000 in 2022.

Statistic 8

Female sex workers accounted for 15,000 new infections in 2022.

Statistic 9

HIV incidence in pregnant women dropped to 2.1% in 2022 from 3.5% in 2015.

Statistic 10

Eastern Cape had 14,200 new adult HIV infections in 2022.

Statistic 11

New infections declined by 68% among children 0-14 since 2010, to 1,800 in 2022.

Statistic 12

Limpopo province reported 8,900 new HIV infections in 2022.

Statistic 13

Western Cape saw 11,500 new cases among adults in 2022.

Statistic 14

Incidence rate in urban informal settlements was 1.2% in 2022 surveys.

Statistic 15

Northern Cape new infections totaled 3,400 in adults 2022.

Statistic 16

Mpumalanga had 15,600 new HIV cases in 2022.

Statistic 17

North West province incidence contributed 12,100 new infections in 2022.

Statistic 18

Free State recorded 9,800 new adult infections in 2022.

Statistic 19

Overall new infections fell 5% from 2021 to 2022 in South Africa.

Statistic 20

In 2022, South Africa accounted for 20% of all people living with HIV globally, with approximately 7.8 million PLHIV out of 39 million worldwide.

Statistic 21

The adult HIV prevalence rate (15-49 years) in South Africa was 19.5% in 2022, the highest in the world.

Statistic 22

HIV prevalence among women aged 15-49 in South Africa reached 25.8% in 2022, compared to 14.2% for men.

Statistic 23

In KwaZulu-Natal province, HIV prevalence among adults was 26.5% in the 2022 survey.

Statistic 24

Gauteng province had an HIV prevalence of 21.4% among adults aged 15-49 in 2022.

Statistic 25

Eastern Cape's adult HIV prevalence stood at 18.9% according to the 2022 national survey.

Statistic 26

Limpopo province reported 17.2% HIV prevalence among adults in 2022.

Statistic 27

In 2022, 12.7% of South Africa's total population was living with HIV.

Statistic 28

Youth aged 15-24 HIV prevalence in South Africa was 5.2% for females and 2.1% for males in 2022.

Statistic 29

Pregnant women HIV prevalence at antenatal clinics averaged 27.8% nationally in 2022.

Statistic 30

HIV prevalence in urban areas of South Africa was 20.1% versus 18.3% in rural areas in 2022.

Statistic 31

Among sex workers in South Africa, HIV prevalence was estimated at 57.7% in 2022.

Statistic 32

MSM HIV prevalence in South Africa averaged 28% in key population surveys of 2022.

Statistic 33

People who inject drugs had 12.5% HIV prevalence in South African cities in 2022.

Statistic 34

Western Cape province HIV prevalence was 16.8% among adults in 2022.

Statistic 35

Northern Cape reported 15.4% adult HIV prevalence in the 2022 survey.

Statistic 36

Mpumalanga's HIV prevalence reached 24.1% for adults aged 15-49 in 2022.

Statistic 37

North West province had 19.7% HIV prevalence in 2022 national data.

Statistic 38

Free State province adult HIV prevalence was 22.3% in 2022.

Statistic 39

Overall, 4.1 million children under 18 in South Africa were affected by HIV in 2022.

Statistic 40

AIDS-related deaths in South Africa numbered 74,000 in 2022, down 58% since 2010.

Statistic 41

Mortality rate among PLHIV was 1.1% in South Africa 2022.

Statistic 42

11,000 children died from AIDS-related causes in South Africa in 2022.

Statistic 43

KwaZulu-Natal recorded 18,500 AIDS deaths in adults 2022.

Statistic 44

Gauteng had 15,200 AIDS-related deaths in 2022.

Statistic 45

TB was the leading cause of AIDS deaths, accounting for 42% in 2022.

Statistic 46

Women accounted for 56% of all AIDS deaths in South Africa 2022.

Statistic 47

Eastern Cape reported 9,800 AIDS deaths in 2022.

Statistic 48

AIDS mortality among adults 15-49 declined 65% since peak in 2006.

Statistic 49

Limpopo had 5,200 AIDS-related deaths in 2022.

Statistic 50

Western Cape AIDS deaths totaled 6,100 in adults 2022.

Statistic 51

Northern Cape recorded 2,000 AIDS deaths in 2022.

Statistic 52

Mpumalanga had 8,900 AIDS-related deaths in 2022.

Statistic 53

North West province deaths from AIDS were 7,500 in 2022.

Statistic 54

Free State reported 6,700 AIDS deaths in 2022 data.

Statistic 55

Orphans due to AIDS numbered 1.2 million children in South Africa 2022.

Statistic 56

Late diagnosis contributed to 25% of AIDS deaths before ART initiation in 2022.

Statistic 57

Pneumocystis pneumonia caused 15% of AIDS mortality in hospitals 2022.

Statistic 58

HIV testing coverage reached 92% among adults 15-49 in South Africa 2022.

Statistic 59

15 million HIV tests were conducted in public facilities in South Africa in 2022.

Statistic 60

Condom use at last high-risk sex was 65% among youth 15-24 in 2022.

Statistic 61

PrEP initiations totaled 250,000 users in South Africa by end of 2022.

Statistic 62

Voluntary medical male circumcision covered 32% of men 15-49 in 2022.

Statistic 63

Knowledge of HIV status was 89% among adults in 2022 surveys.

Statistic 64

85% of adolescent girls knew their HIV status in 2022.

Statistic 65

Multiple sexual partners in past year: 12% for women, 25% for men 2022.

Statistic 66

Mother-to-child transmission rate dropped to 1.3% in 2022.

Statistic 67

Eastern Cape testing positivity rate was 4.2% in 2022.

Statistic 68

Community-based testing reached 2.5 million people in 2022.

Statistic 69

DREAMS program covered 1.1 million AGYW for prevention in 2022.

Statistic 70

Contraceptive use among HIV+ women was 62% in 2022.

Statistic 71

Limpopo self-testing kits distributed: 500,000 in 2022.

Statistic 72

Age-disparate relationships declined to 14% among teen girls 2022.

Statistic 73

Northern Cape prevention coverage for key populations: 55% in 2022.

Statistic 74

Mpumalanga condom distribution: 450 million in 2022.

Statistic 75

North West HIV testing in schools reached 80% of learners 2022.

Statistic 76

Free State PrEP coverage among sex workers: 42% in 2022.

Statistic 77

Transactional sex reported by 10% of women 15-49 in 2022 survey.

Statistic 78

VMMC procedures: 1.2 million cumulative since 2010 by 2022.

Statistic 79

5.6 million people living with HIV in South Africa were on ART in 2022, covering 77% of PLHIV.

Statistic 80

ART coverage among adults 15+ reached 78% in South Africa by end of 2022.

Statistic 81

90% of diagnosed PLHIV in South Africa were virally suppressed in 2022.

Statistic 82

KwaZulu-Natal had 85% ART coverage among adults in 2022.

Statistic 83

Gauteng province achieved 82% of PLHIV on ART in 2022 surveys.

Statistic 84

Viral load suppression rate was 92% among those on ART for over 6 months in 2022.

Statistic 85

Children 0-14 on ART numbered 240,000, or 65% coverage in 2022.

Statistic 86

Pregnant women living with HIV had 97% ART coverage in antenatal care 2022.

Statistic 87

Eastern Cape ART coverage was 75% among adults in 2022.

Statistic 88

Dolutegravir-based regimens were used by 95% of new ART initiators in 2022.

Statistic 89

Limpopo province had 72% ART coverage for PLHIV in 2022.

Statistic 90

Western Cape reported 80% viral suppression among ART patients in 2022.

Statistic 91

Northern Cape ART initiation reached 70% of eligible adults in 2022.

Statistic 92

Mpumalanga had 79% ART coverage in 2022 provincial data.

Statistic 93

North West province ART coverage stood at 76% for adults 2022.

Statistic 94

Free State achieved 81% of PLHIV on treatment in 2022.

Statistic 95

Differentiated service delivery models covered 45% of stable patients in 2022.

Statistic 96

TB/HIV co-infection treatment integration reached 88% in 2022 facilities.

Statistic 97

Retention on ART at 12 months was 87% nationally in South Africa 2022.

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While South Africa carries the staggering burden of being home to 20% of the world's HIV-positive population, a deeper look at the 2022 statistics reveals a complex story of both profound challenge and remarkable progress in the nation's fight against the epidemic.

Key Takeaways

  • In 2022, South Africa accounted for 20% of all people living with HIV globally, with approximately 7.8 million PLHIV out of 39 million worldwide.
  • The adult HIV prevalence rate (15-49 years) in South Africa was 19.5% in 2022, the highest in the world.
  • HIV prevalence among women aged 15-49 in South Africa reached 25.8% in 2022, compared to 14.2% for men.
  • New HIV infections in South Africa totaled 150,000 in 2022, down 44% since 2010.
  • Annual HIV incidence rate among adults 15-49 was 0.73% in South Africa in 2022.
  • 72,000 new HIV infections occurred among adolescent girls and young women aged 15-24 in 2022.
  • 5.6 million people living with HIV in South Africa were on ART in 2022, covering 77% of PLHIV.
  • ART coverage among adults 15+ reached 78% in South Africa by end of 2022.
  • 90% of diagnosed PLHIV in South Africa were virally suppressed in 2022.
  • AIDS-related deaths in South Africa numbered 74,000 in 2022, down 58% since 2010.
  • Mortality rate among PLHIV was 1.1% in South Africa 2022.
  • 11,000 children died from AIDS-related causes in South Africa in 2022.
  • HIV testing coverage reached 92% among adults 15-49 in South Africa 2022.
  • 15 million HIV tests were conducted in public facilities in South Africa in 2022.
  • Condom use at last high-risk sex was 65% among youth 15-24 in 2022.

South Africa has the world's highest HIV rates but is making strong treatment progress.

AIDS Incidence and New Infections

  • New HIV infections in South Africa totaled 150,000 in 2022, down 44% since 2010.
  • Annual HIV incidence rate among adults 15-49 was 0.73% in South Africa in 2022.
  • 72,000 new HIV infections occurred among adolescent girls and young women aged 15-24 in 2022.
  • KwaZulu-Natal saw 28,500 new HIV infections in 2022, the highest provincially.
  • Gauteng recorded 32,000 new HIV cases in adults in 2022.
  • Incidence among young women 15-24 was 4.6% annually in high-prevalence areas in 2022.
  • New infections among MSM were estimated at 12,000 in 2022.
  • Female sex workers accounted for 15,000 new infections in 2022.
  • HIV incidence in pregnant women dropped to 2.1% in 2022 from 3.5% in 2015.
  • Eastern Cape had 14,200 new adult HIV infections in 2022.
  • New infections declined by 68% among children 0-14 since 2010, to 1,800 in 2022.
  • Limpopo province reported 8,900 new HIV infections in 2022.
  • Western Cape saw 11,500 new cases among adults in 2022.
  • Incidence rate in urban informal settlements was 1.2% in 2022 surveys.
  • Northern Cape new infections totaled 3,400 in adults 2022.
  • Mpumalanga had 15,600 new HIV cases in 2022.
  • North West province incidence contributed 12,100 new infections in 2022.
  • Free State recorded 9,800 new adult infections in 2022.
  • Overall new infections fell 5% from 2021 to 2022 in South Africa.

AIDS Incidence and New Infections Interpretation

While headline progress offers a weary cheer, the stubbornly high infections among young women and key populations reveal a battle where alarming local surges stubbornly undermine the national retreat.

HIV Prevalence Rates

  • In 2022, South Africa accounted for 20% of all people living with HIV globally, with approximately 7.8 million PLHIV out of 39 million worldwide.
  • The adult HIV prevalence rate (15-49 years) in South Africa was 19.5% in 2022, the highest in the world.
  • HIV prevalence among women aged 15-49 in South Africa reached 25.8% in 2022, compared to 14.2% for men.
  • In KwaZulu-Natal province, HIV prevalence among adults was 26.5% in the 2022 survey.
  • Gauteng province had an HIV prevalence of 21.4% among adults aged 15-49 in 2022.
  • Eastern Cape's adult HIV prevalence stood at 18.9% according to the 2022 national survey.
  • Limpopo province reported 17.2% HIV prevalence among adults in 2022.
  • In 2022, 12.7% of South Africa's total population was living with HIV.
  • Youth aged 15-24 HIV prevalence in South Africa was 5.2% for females and 2.1% for males in 2022.
  • Pregnant women HIV prevalence at antenatal clinics averaged 27.8% nationally in 2022.
  • HIV prevalence in urban areas of South Africa was 20.1% versus 18.3% in rural areas in 2022.
  • Among sex workers in South Africa, HIV prevalence was estimated at 57.7% in 2022.
  • MSM HIV prevalence in South Africa averaged 28% in key population surveys of 2022.
  • People who inject drugs had 12.5% HIV prevalence in South African cities in 2022.
  • Western Cape province HIV prevalence was 16.8% among adults in 2022.
  • Northern Cape reported 15.4% adult HIV prevalence in the 2022 survey.
  • Mpumalanga's HIV prevalence reached 24.1% for adults aged 15-49 in 2022.
  • North West province had 19.7% HIV prevalence in 2022 national data.
  • Free State province adult HIV prevalence was 22.3% in 2022.
  • Overall, 4.1 million children under 18 in South Africa were affected by HIV in 2022.

HIV Prevalence Rates Interpretation

South Africa's battle with HIV is a national crisis of staggering proportions, where one in five adults carries the virus, a burden shouldered most heavily by women and concentrated in provinces like KwaZulu-Natal, yet its reach is chillingly universal, touching every community from sex workers to children.

Mortality and AIDS-related Deaths

  • AIDS-related deaths in South Africa numbered 74,000 in 2022, down 58% since 2010.
  • Mortality rate among PLHIV was 1.1% in South Africa 2022.
  • 11,000 children died from AIDS-related causes in South Africa in 2022.
  • KwaZulu-Natal recorded 18,500 AIDS deaths in adults 2022.
  • Gauteng had 15,200 AIDS-related deaths in 2022.
  • TB was the leading cause of AIDS deaths, accounting for 42% in 2022.
  • Women accounted for 56% of all AIDS deaths in South Africa 2022.
  • Eastern Cape reported 9,800 AIDS deaths in 2022.
  • AIDS mortality among adults 15-49 declined 65% since peak in 2006.
  • Limpopo had 5,200 AIDS-related deaths in 2022.
  • Western Cape AIDS deaths totaled 6,100 in adults 2022.
  • Northern Cape recorded 2,000 AIDS deaths in 2022.
  • Mpumalanga had 8,900 AIDS-related deaths in 2022.
  • North West province deaths from AIDS were 7,500 in 2022.
  • Free State reported 6,700 AIDS deaths in 2022 data.
  • Orphans due to AIDS numbered 1.2 million children in South Africa 2022.
  • Late diagnosis contributed to 25% of AIDS deaths before ART initiation in 2022.
  • Pneumocystis pneumonia caused 15% of AIDS mortality in hospitals 2022.

Mortality and AIDS-related Deaths Interpretation

The numbers tell a grim, two-faced story: while we've heroically slashed AIDS deaths by over half, the stubborn, unconscionable details—like 11,000 children lost, a million orphans, and women bearing 56% of the burden—prove that our fight is far from won.

Testing, Prevention, and Behavioral Stats

  • HIV testing coverage reached 92% among adults 15-49 in South Africa 2022.
  • 15 million HIV tests were conducted in public facilities in South Africa in 2022.
  • Condom use at last high-risk sex was 65% among youth 15-24 in 2022.
  • PrEP initiations totaled 250,000 users in South Africa by end of 2022.
  • Voluntary medical male circumcision covered 32% of men 15-49 in 2022.
  • Knowledge of HIV status was 89% among adults in 2022 surveys.
  • 85% of adolescent girls knew their HIV status in 2022.
  • Multiple sexual partners in past year: 12% for women, 25% for men 2022.
  • Mother-to-child transmission rate dropped to 1.3% in 2022.
  • Eastern Cape testing positivity rate was 4.2% in 2022.
  • Community-based testing reached 2.5 million people in 2022.
  • DREAMS program covered 1.1 million AGYW for prevention in 2022.
  • Contraceptive use among HIV+ women was 62% in 2022.
  • Limpopo self-testing kits distributed: 500,000 in 2022.
  • Age-disparate relationships declined to 14% among teen girls 2022.
  • Northern Cape prevention coverage for key populations: 55% in 2022.
  • Mpumalanga condom distribution: 450 million in 2022.
  • North West HIV testing in schools reached 80% of learners 2022.
  • Free State PrEP coverage among sex workers: 42% in 2022.
  • Transactional sex reported by 10% of women 15-49 in 2022 survey.
  • VMMC procedures: 1.2 million cumulative since 2010 by 2022.

Testing, Prevention, and Behavioral Stats Interpretation

The statistics reveal a mountain of public health effort is steadily being moved, yet a stubborn molehill of complacency in personal risk behavior still lingers.

Treatment Access and ART

  • 5.6 million people living with HIV in South Africa were on ART in 2022, covering 77% of PLHIV.
  • ART coverage among adults 15+ reached 78% in South Africa by end of 2022.
  • 90% of diagnosed PLHIV in South Africa were virally suppressed in 2022.
  • KwaZulu-Natal had 85% ART coverage among adults in 2022.
  • Gauteng province achieved 82% of PLHIV on ART in 2022 surveys.
  • Viral load suppression rate was 92% among those on ART for over 6 months in 2022.
  • Children 0-14 on ART numbered 240,000, or 65% coverage in 2022.
  • Pregnant women living with HIV had 97% ART coverage in antenatal care 2022.
  • Eastern Cape ART coverage was 75% among adults in 2022.
  • Dolutegravir-based regimens were used by 95% of new ART initiators in 2022.
  • Limpopo province had 72% ART coverage for PLHIV in 2022.
  • Western Cape reported 80% viral suppression among ART patients in 2022.
  • Northern Cape ART initiation reached 70% of eligible adults in 2022.
  • Mpumalanga had 79% ART coverage in 2022 provincial data.
  • North West province ART coverage stood at 76% for adults 2022.
  • Free State achieved 81% of PLHIV on treatment in 2022.
  • Differentiated service delivery models covered 45% of stable patients in 2022.
  • TB/HIV co-infection treatment integration reached 88% in 2022 facilities.
  • Retention on ART at 12 months was 87% nationally in South Africa 2022.

Treatment Access and ART Interpretation

South Africa’s HIV response is like a complex machine that, despite a few stubbornly squeaky provincial gears, has managed to get the vast majority of its cogs turning and humming along beautifully.