Key Takeaways
- Smoking causes about 90% of all lung cancer deaths in men and 80% in women in the United States
- Cigarette smoking is responsible for approximately 480,000 deaths per year in the US, with 30% attributed to lung cancer
- Smokers are 15 to 30 times more likely to die from lung cancer than nonsmokers
- Smoking increases coronary heart disease risk by 2 to 4 times
- Smokers are 2 to 4 times more likely to develop peripheral artery disease
- Smoking causes about 1 of every 4 deaths from coronary heart disease in the US
- Smoking causes COPD in 80-90% of cases
- Smokers are 12-13 times more likely to die from COPD than nonsmokers
- Smoking accounts for 85% of COPD deaths in the US
- Smoking during pregnancy increases low birth weight risk by 2-fold
- Maternal smoking causes 10% of all preterm births
- Infants of smokers have 2-4 times higher risk of sudden infant death syndrome (SIDS)
- Secondhand smoke causes 41,000 deaths per year in US nonsmokers
- Smoking kills over 8 million people worldwide annually, including 1.2 million from secondhand smoke
- Smokers die 10 years prematurely on average
Smoking causes widespread cancer, heart disease, lung damage, and early death.
Cancer Risks
- Smoking causes about 90% of all lung cancer deaths in men and 80% in women in the United States
- Cigarette smoking is responsible for approximately 480,000 deaths per year in the US, with 30% attributed to lung cancer
- Smokers are 15 to 30 times more likely to die from lung cancer than nonsmokers
- Smoking increases the risk of developing laryngeal cancer by 10 to 20 times compared to nonsmokers
- Oral cavity and pharyngeal cancers have a relative risk of 5 to 25 times higher in smokers versus nonsmokers
- Esophageal cancer risk is 5 times higher for current smokers compared to never smokers
- Bladder cancer incidence is twice as high in smokers as in nonsmokers
- Smoking accounts for 70% of stomach cancer deaths worldwide
- Pancreatic cancer risk increases by 2 to 3 times in heavy smokers
- Cervix cancer risk is 1.6 times higher in women who smoke compared to nonsmokers
- Kidney cancer relative risk is 1.5 to 2.5 for smokers
- Myeloid leukemia risk doubles in cigarette smokers
- Smoking contributes to 12% of all cancer deaths in the US annually
- Long-term smokers have a 20-fold increased risk of squamous cell carcinoma of the lung
- Adenocarcinoma of the lung risk is 5-10 times higher in smokers
- Small cell lung cancer is almost exclusively caused by smoking, with 95% of cases linked
- Colorectal cancer risk increases by 20-30% in smokers
- Liver cancer risk is 50% higher in smokers
- Smoking raises prostate cancer mortality risk by 24-30%
- Breast cancer risk may increase by 30% in premenopausal women who smoke
- Smoking is linked to 85% of head and neck cancers
- Risk of multiple myeloma is 1.4 times higher in smokers
- Smokers have a 2-4 times higher risk of sinonasal cancer
- Thyroid cancer risk slightly elevated by 20% in smokers
- Smoking accounts for 36% of all cancer mortality in men globally
- Women smokers have 2.3 times higher risk of anal cancer
- Heavy smoking increases gallbladder cancer risk by 2-fold
- Smoking cessation reduces lung cancer risk by 50% after 10 years
- Filtered cigarettes do not reduce cancer risk, with similar rates to non-filtered
- Menthol cigarettes increase lung cancer risk by 15% more than non-menthol
- Smoking causes 1 in 5 cancer deaths in California annually
- Cigarette smoking is the leading cause of preventable cancer death, responsible for 167,133 deaths in 2019 in the EU
Cancer Risks Interpretation
Cardiovascular Risks
- Smoking increases coronary heart disease risk by 2 to 4 times
- Smokers are 2 to 4 times more likely to develop peripheral artery disease
- Smoking causes about 1 of every 4 deaths from coronary heart disease in the US
- Stroke risk is 2 to 4 times higher in smokers compared to nonsmokers
- Smoking accounts for 33% of deaths from coronary heart disease globally
- Abdominal aortic aneurysm risk is 5 times higher in smokers
- Smokers have a 70% higher risk of atrial fibrillation
- Smoking cessation reduces heart disease risk by 50% within 1 year
- Secondhand smoke exposure increases heart disease risk by 25-30%
- Smoking damages blood vessels, leading to atherosclerosis in 80% of smokers over 40
- Heavy smokers have 4 times the risk of sudden cardiac death
- Smoking increases blood pressure by 10-20 mmHg acutely
- Smokers are 2 times more likely to have a heart attack before age 60
- Nicotine constricts coronary arteries by 25-30%
- Smoking doubles the risk of heart failure
- Women smokers have 5.5 times higher risk of peripheral vascular disease
- Smoking accounts for 20% of cardiovascular deaths in low-income countries
- Bidis smoking increases MI risk by 4-fold
- Pipe smokers have 3.5 times higher CHD risk
- Cigar smokers have 27% higher risk of CHD death
- Smokeless tobacco increases CVD risk by 1.4 times
- E-cigarette use raises acute MI risk by 56%
- Smoking impairs endothelial function by 50% within minutes
- Smokers have 2.5 times higher carotid artery stenosis risk
- Chronic smoking increases ventricular arrhythmias by 2-fold
- Smoking is associated with 15% higher risk of venous thromboembolism
- Quitting smoking at age 30 adds 10 years to life expectancy from CVD prevention
Cardiovascular Risks Interpretation
Reproductive and Developmental Risks
- Smoking during pregnancy increases low birth weight risk by 2-fold
- Maternal smoking causes 10% of all preterm births
- Infants of smokers have 2-4 times higher risk of sudden infant death syndrome (SIDS)
- Smoking reduces fertility by 30% in women
- Ectopic pregnancy risk is 1.6 times higher in smokers
- Placental abruption risk doubles in smokers
- Stillbirth risk increases by 50% with maternal smoking
- Smoking causes 5-10% growth restriction in fetuses
- Male smokers have 20-30% lower sperm quality
- Smoking increases miscarriage risk by 20-30%
- Children of smokers have 20% higher risk of childhood obesity
- Maternal smoking linked to 1.5 times ADHD risk in offspring
- Paternal smoking increases childhood leukemia risk by 25%
- Smoking worsens menopausal symptoms and osteoporosis risk by 20%
- Erectile dysfunction risk is 1.5-2 times higher in smokers
- Smoking delays conception by 2-3 months on average
- Secondhand smoke exposure reduces fetal growth by 100-200g
- Smoking increases preeclampsia risk by 20%
- Offspring of smokers have 15% higher risk of type 2 diabetes
- Smoking accelerates ovarian aging by 2 years
- Breastfeeding mothers who smoke have 2-fold higher mastitis risk
- Children exposed prenatally to smoke have 50% more respiratory infections
- Smoking increases endometrial cancer risk by 2-fold
- Quitting smoking improves fertility within 1 year by 30%
Reproductive and Developmental Risks Interpretation
Respiratory Risks
- Smoking causes COPD in 80-90% of cases
- Smokers are 12-13 times more likely to die from COPD than nonsmokers
- Smoking accounts for 85% of COPD deaths in the US
- Emphysema is caused by smoking in 90% of cases
- Chronic bronchitis prevalence is 4 times higher in smokers
- Smoking reduces lung function by 20-30 mL/year more than nonsmokers
- Smokers have 50% higher risk of pneumonia hospitalization
- Tuberculosis risk increases 3-fold in active smokers
- Asthma exacerbations are 40% more frequent in smokers
- Smoking worsens idiopathic pulmonary fibrosis progression by 2-fold
- Respiratory infections risk is 2-4 times higher in smokers
- Smoking causes 73,000 asthma-related hospitalizations yearly in US adults
- Pipe smoking increases COPD risk by 5-fold
- Waterpipe smoking impairs lung function equivalent to 100 cigarettes/day
- Smoking cessation slows FEV1 decline by 50 mL/year
- Smokers have 3 times higher risk of bronchiectasis
- Smoking increases acute respiratory distress syndrome risk by 3.5-fold
- Sarcoidosis progression is faster in smokers by 20%
- Smoking causes bullous lung disease in 15-20% of cases
- Interstitial lung disease risk doubles in smokers
- Smoking exacerbates cystic fibrosis lung decline by 30%
- Occupational asthma is 2 times more severe in smokers
- Smoking increases ventilator-associated pneumonia by 2-fold
- Smokers lose 10 years of life expectancy due to COPD
Respiratory Risks Interpretation
Secondhand Smoke and Mortality Risks
- Secondhand smoke causes 41,000 deaths per year in US nonsmokers
- Smoking kills over 8 million people worldwide annually, including 1.2 million from secondhand smoke
- Smokers die 10 years prematurely on average
- Tobacco kills more than 480,000 Americans yearly
- Quitting at 40 avoids 9/10 premature deaths from smoking
- Secondhand smoke increases lung cancer risk by 20-30% in nonsmokers
- Smoking causes 100 million deaths in 20th century, projected 1 billion in 21st
- 1.3 billion tobacco users globally
- Secondhand smoke causes 400,000 asthma attacks in US children yearly
- Smokeless tobacco causes 8% of US tobacco deaths
- Global smoking-attributable mortality is 7.7 million/year
- Secondhand smoke stroke risk up 20-30%
- Hookah smoke exposure equivalent to 100 cigarettes in toxins
- Smoking costs US $300 billion/year in healthcare and productivity
- 16 million Americans live with smoking-related disease
- Secondhand smoke causes 7,300 lung cancer deaths/year in US
- Every smoker loses 11 minutes of life per cigarette smoked
- Tobacco epidemic kills 50% of long-term users prematurely
- Secondhand smoke otitis media risk up 63% in children
- Global Youth Tobacco Survey shows 37 million kids smoke daily
- Smoking cessation adds 10 years life expectancy if quit before 40
- Secondhand smoke increases breast cancer risk by 10-20%
- E-cigarette secondhand aerosol increases particulate exposure by 10-fold
- Smoking-related diseases cost EU €25 billion/year
Secondhand Smoke and Mortality Risks Interpretation
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