Key Takeaways
- In the United States, as of October 2023, there are over 103,000 people on the national organ transplant waiting list
- Approximately 17 people die each day in the US waiting for an organ transplant
- In 2022, 42,887 organ transplants were performed in the US from 21,370 deceased donors
- In 2022, US deceased donors increased by 10.6% to 21,370
- Living donors in US: 6,449 in 2022, up 20% since 2019
- Average age of deceased donors in US: 40 years in 2022
- In 2022, US procured 42,887 kidneys from deceased donors
- Livers: 20,952 procured in US 2022 from deceased donors
- Hearts: 4,111 hearts transplanted US 2022
- 1-year kidney graft survival from deceased donor: 94% US 2022
- 5-year kidney survival: 83% deceased donor, 92% living donor US
- Liver 1-year survival: 92% US 2022 transplants
- In 2023 survey, 95% of US adults have heard of organ donation
- Organ donation registration rate US: 60% of adults 2023
- Spain's opt-out policy led to 48 pmp donors, vs opt-in 10-20 pmp
Organ donor shortages cause many deaths despite overwhelming public support.
Awareness and Policy Impacts
- In 2023 survey, 95% of US adults have heard of organ donation
- Organ donation registration rate US: 60% of adults 2023
- Spain's opt-out policy led to 48 pmp donors, vs opt-in 10-20 pmp
- UK's 2020 opt-out law increased consent rate to 90%
- Family consent overrides registration in 20% US cases
- Donate Life America campaigns reached 200 million impressions 2022
- Religious barriers: 10% of US non-registrants cite religion, 2023 survey
- Driver's license registration: 50% of US states use it primarily
- Global awareness: 70% know about donation, but 40% willing, WHO survey
- Social media influence: 30% of young adults register after seeing posts
- School education programs increase teen registration by 25%
- Minority registration rates: Hispanics 48%, Blacks 42% US 2023
- Policy change: US NOTA 1984 banned organ sales
- Iran's regulated living kidney sales: 1,000/year, unique policy
- Presumed consent countries: 40+ globally, higher donation rates
- US HRSA campaigns increased registration 15% in targeted areas
- Family discussion rate: only 30% of US families discuss wishes
- Workplace registration drives: boost by 20% in companies
- COVID-19 impact: donation rates dropped 20% in 2020, recovered 2022
Awareness and Policy Impacts Interpretation
Donor Demographics and Rates
- In 2022, US deceased donors increased by 10.6% to 21,370
- Living donors in US: 6,449 in 2022, up 20% since 2019
- Average age of deceased donors in US: 40 years in 2022
- Male donors: 60% of deceased donors in US 2022
- White donors: 58% of US deceased donors, 2022
- Hispanic donors: 18% in US 2022
- Black donors: 14% of US deceased donors 2022
- Asian donors: 6% in US 2022
- Cause of death for 35% of US deceased donors: head trauma, 2022
- Stroke: 25% cause of death for deceased donors US 2022
- Drug overdose: 15% of US deceased donors in 2022
- Spain: 48 deceased donors per million population (pmp) in 2022, world's highest
- US donor rate: 44 pmp deceased donors in 2022
- UK: 23 pmp deceased donors in 2022/23
- Croatia: 40 pmp, highest in Europe after Spain, 2022
- Living kidney donation rate US: 19 pmp in 2022
- 40% of US living donors are biologically related to recipient, 2022
- Paired kidney exchange programs facilitated 10% of living kidney transplants US 2022
- Global deceased donor rate average: 2.4 pmp, WHO 2023
- India: 0.7 pmp deceased donors, very low, 2023
- China: increasing to 4 pmp deceased donors 2022
- Average BMI of US deceased donors: 28.5 in 2022
- 25% of US deceased donors had COVID-19 history, but recoverable, 2022
- Pediatric donors (under 18): 2% of US total deceased donors 2022
- Female living donors: 60% in US 2022
- Donor registration via DMV: 58% of US adults registered 2023
Donor Demographics and Rates Interpretation
Organ Procurement and Types
- In 2022, US procured 42,887 kidneys from deceased donors
- Livers: 20,952 procured in US 2022 from deceased donors
- Hearts: 4,111 hearts transplanted US 2022
- Lungs: 6,783 lung transplants US 2022
- Pancreases: 1,098 pancreas transplants US 2022
- Intestines: 138 intestine transplants US 2022
- Kidneys from living donors: 6,449 in US 2022
- Liver lobes from living donors: 322 split liver transplants US 2022
- Corneas: over 80,000 transplanted annually in US
- Skin grafts from donors: millions of sq inches annually US
- Heart valves: 2,000-3,000 transplanted yearly US from donors
- Bone tissue: 1 million grafts from donors US annually
- One deceased donor can provide up to 8 organs for transplant
- DCD (donation after circulatory death): 23% of US deceased donors 2022
- DBD (brain death): 77% of US deceased donors 2022
- Spain procured 2,179 deceased donors in 2022, leading Europe
- UK: 1,913 deceased donors in 2022/23
- Global kidney transplants: over 100,000 annually, WHO estimate
- Liver transplants worldwide: 30,000-40,000 per year
- VCA (vascularized composite allografts) like hands: 100+ worldwide cumulative
- Uterus transplants: 100 performed globally by 2023
- In US, 90% of procured kidneys are transplanted, discard rate 10%
- Liver discard rate: 15% in US 2022
- One donor yields average 3.5 organs transplanted US 2022
- Global tissue donation: millions of grafts yearly
Organ Procurement and Types Interpretation
Transplant Success and Outcomes
- 1-year kidney graft survival from deceased donor: 94% US 2022
- 5-year kidney survival: 83% deceased donor, 92% living donor US
- Liver 1-year survival: 92% US 2022 transplants
- Heart 1-year survival: 91% US 2022
- Lung 1-year survival: 85% US 2022
- Pancreas 1-year: 94% graft survival US 2022
- Kidney-pancreas combined: 95% 1-year patient survival US
- Intestine 1-year survival: 70% US 2022
- Pediatric heart transplant 1-year survival: 95% US
- Re-transplant rate for kidneys: 5% within 5 years US
- Acute rejection kidney: 10-15% first year US
- Chronic rejection contributes to 30% graft losses after 5 years
- Immunosuppression adherence: 80% compliance improves 5-year survival to 90%
- Spain liver transplant 5-year survival: 75%
- UK kidney 1-year survival: 95%
- Global kidney transplant half-life: 15 years living donor, 10 years deceased
- Post-transplant diabetes: 10-20% kidney recipients US
- Infection cause of 15% post-transplant deaths US
- Cancer risk post-transplant: 2-3x higher than general population
- CMV infection: 20-60% first year without prophylaxis
- Living donor kidney survival superior by 10% at 10 years
- Heart retransplant 1-year survival: 80% vs 91% primary
- Lung transplant median survival: 6.4 years US 2022
- Quality-adjusted life years gained: 7-10 per kidney transplant
- 20-year kidney graft survival: 40% US deceased donor
Transplant Success and Outcomes Interpretation
Waiting List and Recipients
- In the United States, as of October 2023, there are over 103,000 people on the national organ transplant waiting list
- Approximately 17 people die each day in the US waiting for an organ transplant
- In 2022, 42,887 organ transplants were performed in the US from 21,370 deceased donors
- Kidney transplants account for 86% of the US waiting list, with over 88,000 candidates as of 2023
- Liver waiting list in the US stands at about 10,700 patients in 2023
- Heart transplants: 3,500 patients on US waiting list in 2023
- Lung waiting list: around 1,500 candidates in the US as of 2023
- Intestine waiting list: fewer than 300 patients in the US in 2023
- Pancreas waiting list: about 800 patients in the US, 2023 data
- In 2022, 6,000 living donors provided organs in the US, primarily kidneys and livers
- Pediatric patients (under 18) make up 2% of the US waiting list, around 2,000 children in 2023
- 40% of US waiting list patients are over 50 years old, as of 2023
- Blood type O patients comprise 40% of the kidney waiting list in the US
- In Europe, Eurotransplant waiting list had 15,000 patients in 2022
- UK active transplant waiting list: 7,000 patients as of 2023
- Canada: over 3,000 on organ waiting list in 2023
- Australia: 1,500 on active waiting list for organs in 2023
- India: estimated 300,000 patients waiting for kidney transplants annually
- Brazil: over 60,000 on kidney waiting list in 2023
- In 2022, US pediatric kidney waiting list averaged 900 children
- Hispanic/Latino patients: 22% of US waiting list in 2023
- Black/African American: 29% of US kidney waiting list despite being 13% of population
- Women comprise 42% of the US organ waiting list
- Average wait time for kidney transplant in US: 3-5 years
- 95% of US adults support organ donation, but only 60% registered, 2023 survey
- Global waiting list exceeds 150,000 for kidneys alone, WHO estimate 2023
- In Spain, waiting list mortality rate is 10% lower than EU average due to high donation rates
- France: 18,000 on waiting list in 2023
- Germany: 10,000 organ waiting list patients in 2023
- Japan: over 15,000 waiting for kidneys, low deceased donation rate
Waiting List and Recipients Interpretation
Sources & References
- Reference 1UNOSunos.orgVisit source
- Reference 2OPTNoptn.transplant.hrsa.govVisit source
- Reference 3EUROTRANSPLANTeurotransplant.orgVisit source
- Reference 4NHSBTnhsbt.nhs.ukVisit source
- Reference 5CIHIcihi.caVisit source
- Reference 6DONATELIFEdonatelife.gov.auVisit source
- Reference 7NOTTOnotto.mohfw.gov.inVisit source
- Reference 8ABTOabto.org.brVisit source
- Reference 9ORGANDONORorgandonor.govVisit source
- Reference 10WHOwho.intVisit source
- Reference 11ONTont.esVisit source
- Reference 12AGENCE-BIOMEDECINEagence-biomedecine.frVisit source
- Reference 13JOTNWjotnw.or.jpVisit source
- Reference 14CHINAORGANHARVESTchinaorganharvest.orgVisit source
- Reference 15LIONSCLUBSlionsclubs.orgVisit source
- Reference 16AATSaats.orgVisit source
- Reference 17AATBaatb.orgVisit source
- Reference 18ILTSilts.orgVisit source
- Reference 19IFVCAifvca.orgVisit source
- Reference 20ISHLTishlt.orgVisit source
- Reference 21KIDNEYkidney.orgVisit source
- Reference 22NCBIncbi.nlm.nih.govVisit source
- Reference 23ISHLTREGISTRIESishltregistries.orgVisit source
- Reference 24DONATELIFEdonatelife.netVisit source
- Reference 25GALLUPgallup.comVisit source





