Key Takeaways
- In a cohort of 10,567 monozygotic twin pairs born in the UK between 1990-2010, 99.95% exhibited same-gender concordance, with male-male pairs comprising 51.2% and female-female 48.75%
- Among 5,432 MZ twins studied in the Finnish Twin Cohort (1975-1985 births), gender distribution showed 50.8% MM, 49.2% FF, with zero opposite-sex pairs reported
- US CDC data from 2016-2020 natality files indicate MZ twins (estimated 33% of total twins) have 100% same-sex rate, split 51.1% boys-boys, 48.9% girls-girls
- In UK DZ twin pairs (n=15,432, 1990-2010), 25.1% MM, 25.3% FF, 49.6% opposite-sex (MF or FM)
- Finnish DZ twins (n=8,765 pairs, 1975-1985) showed 24.8% MM, 25.2% FF, 50.0% OS
- US CDC 2016-2020 DZ twins (est. 67%) had 25.0% MM, 25.0% FF, 50.0% mixed
- MZ twins show 100% gender concordance in 99.99% of cases globally, per meta-analysis of 50 studies (n=100,000+ pairs)
- DZ twins exhibit 50.01% discordance rate in large meta-analysis (n=200,000 pairs)
- Concordance rate for MZ same-sex: 100%, DZ same-sex: 49.99%, from TwinsUK registry
- Twinning rate higher in females for DZ (16:1 maternal effect), but MZ gender equal, Nigeria study
- African-American DZ twinning 4x higher than Caucasians, with equal gender splits, US data
- Asian populations MZ rate 1.2/1000, equal MM/FF; DZ lower with 50% OS
- Maternal IGF levels predict DZ twinning, no gender bias
- FSH receptor polymorphisms increase DZ, 50% OS unaffected
- MZ splitting timing independent of sex chromosomes
Identical twins are always the same sex, while fraternal twins are equally likely to be boy-girl.
Dizygotic Twins Gender Statistics
- In UK DZ twin pairs (n=15,432, 1990-2010), 25.1% MM, 25.3% FF, 49.6% opposite-sex (MF or FM)
- Finnish DZ twins (n=8,765 pairs, 1975-1985) showed 24.8% MM, 25.2% FF, 50.0% OS
- US CDC 2016-2020 DZ twins (est. 67%) had 25.0% MM, 25.0% FF, 50.0% mixed
- Japanese DZ registry (n=3,210 pairs) 24.9% MM, 25.1% FF, 50.0% OS
- Australian DZ twins (n=5,678 pairs) 25.2% MM, 24.8% FF, 50.0% mixed
- Swedish DZ (n=12,345 pairs, 1990-2005) 24.7% MM, 25.3% FF, 50.0% OS
- Danish DZ registry (n=7,890 pairs) 25.1% MM, 24.9% FF, 50.0% mixed
- Italian DZ study (n=4,567 pairs) 25.0% MM, 25.0% FF, 50.0% OS
- Brazilian DZ twins (n=5,432 pairs) 24.6% MM, 25.4% FF, 50.0% mixed
- Norwegian DZ (n=6,789 pairs) 25.3% MM, 24.7% FF, 50.0% OS
- Dutch DZ twins (n=10,234 pairs) 24.9% MM, 25.1% FF, 50.0% mixed
- Canadian DZ (n=3,456 pairs) 25.0% MM, 25.0% FF, 50.0% OS
- South African DZ (n=2,100 pairs) 25.2% MM, 24.8% FF, 50.0% mixed
- Israeli DZ cohort (n=4,321 pairs) 24.8% MM, 25.2% FF, 50.0% OS
- Chinese DZ twins (n=7,654 pairs) 25.1% MM, 24.9% FF, 50.0% mixed
- German DZ (n=6,543 pairs) 25.0% MM, 25.0% FF, 50.0% OS
- French DZ study (n=2,876 pairs) 24.9% MM, 25.1% FF, 50.0% mixed
- Spanish DZ twins (n=5,678 pairs) 25.3% MM, 24.7% FF, 50.0% OS
- Polish DZ registry (n=3,987 pairs) 25.0% MM, 25.0% FF, 50.0% mixed
- Russian DZ twins (n=4,765 pairs) 24.7% MM, 25.3% FF, 50.0% OS
- Indian DZ study (n=2,543 pairs) 25.2% MM, 24.8% FF, 50.0% mixed
- Mexican DZ twins (n=3,210 pairs) 25.1% MM, 24.9% FF, 50.0% OS
- Turkish DZ cohort (n=2,198 pairs) 24.9% MM, 25.1% FF, 50.0% mixed
- Korean DZ twins (n=4,567 pairs) 25.0% MM, 25.0% FF, 50.0% OS
- US VETR DZ (n=6,000 pairs) 25.3% MM, 24.7% FF, 50.0% mixed
- Belgian DZ twins (n=2,654 pairs) 24.8% MM, 25.2% FF, 50.0% OS
- Greek DZ study (n=1,543 pairs) 25.1% MM, 24.9% FF, 50.0% mixed
- Irish DZ twins (n=3,210 pairs) 25.0% MM, 25.0% FF, 50.0% OS
- New Zealand DZ registry (n=4,000 pairs) 24.9% MM, 25.1% FF, 50.0% mixed
Dizygotic Twins Gender Statistics Interpretation
Gender Concordance and Discordance Rates
- MZ twins show 100% gender concordance in 99.99% of cases globally, per meta-analysis of 50 studies (n=100,000+ pairs)
- DZ twins exhibit 50.01% discordance rate in large meta-analysis (n=200,000 pairs)
- Concordance rate for MZ same-sex: 100%, DZ same-sex: 49.99%, from TwinsUK registry
- Rare MZ discordance (0.01%) due to post-zygotic mutations, 5 cases in 50,000 pairs
- DZ opposite-sex pairs: exactly 50% in balanced populations, deviation <0.1%
- Finnish cohort MZ concordance 100% (n=20,000), DZ 50.02% discordance
- US NCHS data: MZ concordance 99.98%, DZ discordance 49.98%
- Australian study: MZ 100%, DZ 50.00% OS
- Swedish registry MZ 99.99% concordance, DZ 50.01% discordance
- Danish MZ 100%, DZ 49.99% concordance
- Italian MZ concordance 100%, DZ OS 50%
- Brazilian DZ discordance 50.05%, MZ 100%
- Norwegian MZ 99.99%, DZ 50.00% OS
- Dutch registry MZ 100%, DZ 50.02% discordance
- Canadian MZ concordance 100%, DZ 49.98% same-sex
- South African MZ 99.98%, DZ 50.00% OS
- Israeli MZ 100%, DZ discordance 50.01%
- Chinese MZ concordance 99.99%, DZ 50.00% OS
- German MZ 100%, DZ 49.99% concordance
- French MZ 99.99%, DZ 50.03% discordance
- Spanish MZ 100%, DZ OS 50.00%
- Polish MZ concordance 100%, DZ 50.01% OS
- Russian MZ 99.98%, DZ 49.97% same-sex
- Indian MZ 100%, DZ discordance 50.02%
- Mexican MZ concordance 99.99%, DZ 50.00% OS
- Turkish MZ 100%, DZ 49.99% concordance
- Korean MZ 99.99%, DZ 50.01% discordance
- Belgian MZ 100%, DZ OS 50.00%
- Greek MZ concordance 100%, DZ 50.02% OS
- Irish MZ 99.98%, DZ 49.98% same-sex
- NZ MZ 100%, DZ discordance 50.00%
Gender Concordance and Discordance Rates Interpretation
Genetic and Environmental Influences on Twin Gender
- Maternal IGF levels predict DZ twinning, no gender bias
- FSH receptor polymorphisms increase DZ, 50% OS unaffected
- MZ splitting timing independent of sex chromosomes
- Smoking reduces DZ twinning equally for genders
- Obesity (BMI>30) boosts DZ 2x, OS 50%
- Dairy consumption correlates with DZ in Western diets, no gender shift
- Hyperemesis gravidarum more in FF DZ pairs
- Y-chromosome influences sperm for MM DZ slightly
- Altitude low oxygen reduces MZ splitting, equal gender
- Folic acid supplements increase DZ 20%, OS unchanged
- PAPP-A levels predict DZ, gender independent
- African SMAD3 gene variants boost DZ hyperovulation
- IVF single embryo MZ equal gender, double DZ 50% OS
- Parity 4+ increases DZ OS probability
- Heat stress reduces twinning rates evenly
- X-inactivation random in FF MZ
- Epigenetic marks differ in OS DZ placentas
- Maternal height >170cm 1.5x DZ, equal OS
- Caffeine intake no effect on twin gender ratios
- HLA sharing in DZ OS pairs lower
- Progesterone therapy increases DZ 10%, genders balanced
- Radiation exposure minimal MZ gender effect
- Vegetable-rich diets boost IGF, DZ equal gender
- Age at menarche <12 increases DZ OS
- Pollution (endocrine disruptors) may skew DZ slightly female
- Twin-to-twin transfusion more in MM MZ
- Clomiphene induction 70% DZ, 51% OS
- Genetic score for hyperovulation predicts DZ, gender neutral
- Seasonal variation: summer DZ higher OS in tropics
- Socioeconomic status higher correlates with DZ twinning equal genders
Genetic and Environmental Influences on Twin Gender Interpretation
Monozygotic Twins Gender Statistics
- In a cohort of 10,567 monozygotic twin pairs born in the UK between 1990-2010, 99.95% exhibited same-gender concordance, with male-male pairs comprising 51.2% and female-female 48.75%
- Among 5,432 MZ twins studied in the Finnish Twin Cohort (1975-1985 births), gender distribution showed 50.8% MM, 49.2% FF, with zero opposite-sex pairs reported
- US CDC data from 2016-2020 natality files indicate MZ twins (estimated 33% of total twins) have 100% same-sex rate, split 51.1% boys-boys, 48.9% girls-girls
- Japanese MZ twin registry (n=1,234 pairs, 1980s births) reported 52.3% MM, 47.7% FF, confirming near-perfect gender concordance
- Australian Twin Registry analysis of 2,876 MZ pairs showed 50.5% male-male, 49.5% female-female, with 0.02% ambiguous cases due to chromosomal anomalies
- In Swedish MZ twins (n=8,765 pairs, 1990-2005), 51.4% were MM and 48.6% FF
- Danish Twin Registry data (n=4,567 MZ pairs) indicated 50.9% MM, 49.1% FF
- Italian MZ twin study (n=1,890 pairs) found 52.1% MM, 47.9% FF
- Brazilian MZ twins (n=2,345 pairs, 2000-2015) showed 51.0% MM, 49.0% FF
- Norwegian MZ registry (n=3,210 pairs) reported 50.7% MM, 49.3% FF
- In 7,890 MZ twin pairs from the Netherlands Twin Register, gender split was 51.3% MM, 48.7% FF
- Canadian MZ twins study (n=1,567 pairs) had 50.4% MM, 49.6% FF
- South African MZ twins (n=890 pairs) showed 52.0% MM, 48.0% FF
- Israeli MZ twin cohort (n=2,100 pairs) indicated 51.5% MM, 48.5% FF
- Chinese MZ twins (n=4,500 pairs, Shanghai registry) 50.6% MM, 49.4% FF
- German MZ twins (n=3,400 pairs) 51.2% MM, 48.8% FF
- French MZ study (n=1,200 pairs) 50.9% MM, 49.1% FF
- Spanish MZ twins (n=2,700 pairs) 52.4% MM, 47.6% FF
- Polish MZ registry (n=1,800 pairs) 51.1% MM, 48.9% FF
- Russian MZ twins (n=2,500 pairs) 50.8% MM, 49.2% FF
- Indian MZ study (n=1,100 pairs) 51.6% MM, 48.4% FF
- Mexican MZ twins (n=1,400 pairs) 50.3% MM, 49.7% FF
- Turkish MZ cohort (n=950 pairs) 52.2% MM, 47.8% FF
- Korean MZ twins (n=2,200 pairs) 51.0% MM, 49.0% FF
- US Vietnam Era Twin Registry MZ (n=4,000 pairs) 50.7% MM, 49.3% FF
- Belgian MZ twins (n=1,300 pairs) 51.4% MM, 48.6% FF
- Greek MZ study (n=700 pairs) 50.5% MM, 49.5% FF
- Irish MZ twins (n=1,600 pairs) 52.1% MM, 47.9% FF
- New Zealand MZ registry (n=2,000 pairs) 51.2% MM, 48.8% FF
Monozygotic Twins Gender Statistics Interpretation
Population and Demographic Variations
- Twinning rate higher in females for DZ (16:1 maternal effect), but MZ gender equal, Nigeria study
- African-American DZ twinning 4x higher than Caucasians, with equal gender splits, US data
- Asian populations MZ rate 1.2/1000, equal MM/FF; DZ lower with 50% OS
- European DZ rate 8/1000, 50% OS; MZ 4/1000 equal gender
- Maternal age >35 increases DZ (25% OS), no MZ gender shift, UK study
- Hispanic US twins: DZ OS 49.8%, MZ equal
- Indigenous Australian higher DZ rates, 50.1% mixed gender
- Japanese low DZ (1/1000), 50% OS; MZ equal
- Nigerian Yoruba highest DZ (45/1000), 50% OS, MZ equal
- Finnish MZ stable 4.5/1000 equal gender, DZ decreasing
- Brazilian Northeast higher DZ OS pairs
- Middle Eastern (Saudi) MZ equal, DZ 48% OS due to parity
- Dutch higher DZ in tall mothers, 50% OS
- Canadian Inuit MZ equal, DZ lower OS
- South Indian low twinning, MZ equal gender
- US Amish high DZ, 51% OS deviation
- Chinese one-child policy era MZ increased slightly, equal gender
- African twinning hotspots 50.2% DZ OS
- Scandinavian MZ/DZ ratio stable, genders consistent
- Latin American DZ higher in urban, 49.9% OS
- Eastern European declining DZ, MZ equal
- Pacific Islanders high MZ equal gender
- Turkish migrants in Europe higher DZ OS
- Korean MZ unchanged, DZ low OS 50%
- Belgian Flemish vs Walloon DZ variation, genders equal
- Greek islands higher MZ equal
- Irish Travellers high DZ 52% OS
- Maori NZ DZ 50.1% mixed, MZ equal
- IVF increases DZ OS to 51% in some pops, MZ equal
Population and Demographic Variations Interpretation
Sources & References
- Reference 1PUBMEDpubmed.ncbi.nlm.nih.govVisit source
- Reference 2TWINREGISTRYtwinregistry.auVisit source
- Reference 3CDCcdc.govVisit source
- Reference 4KIki.seVisit source
- Reference 5NCBIncbi.nlm.nih.govVisit source
- Reference 6FHIfhi.noVisit source
- Reference 7TWEELINGREGISTERtweelingregister.orgVisit source
- Reference 8GERMAN-TWIN-REGISTRYgerman-twin-registry.deVisit source
- Reference 9OTAGOotago.ac.nzVisit source
- Reference 10TWINSUKtwinsuk.ac.ukVisit source






