Metastatic Breast Cancer Survival Statistics

GITNUXREPORT 2026

Metastatic Breast Cancer Survival Statistics

See how survival diverges across race, geography, and treatment eras, from a 32.4% 5 year relative survival for distant stage IV breast cancer to real world median overall survival of 39.1 months across 13,760 patients. Then watch the gap sharpen by context such as uninsured patients living a median 20 months versus 36 months with insurance, and men at 19.8% 5 year survival versus 31.3% for women.

129 statistics5 sections8 min readUpdated 16 days ago

Key Statistics

Statistic 1

Black race vs White OS HR 1.25 in US MBC data

Statistic 2

Age 65-74 at MBC diagnosis 5-yr OS 28% vs 35% age 50-64

Statistic 3

Hispanic women MBC median OS 32 months vs 38 non-Hispanic white

Statistic 4

Rural residence OS HR 1.15 vs urban in MBC

Statistic 5

Low SES quintile 1 5-yr OS 25% vs 35% high SES

Statistic 6

Asian/Pacific Islander MBC 5-yr OS 38% highest among races

Statistic 7

Uninsured MBC patients median OS 20 months vs 36 insured

Statistic 8

Male MBC 5-yr OS 19.8% vs 31.3% female

Statistic 9

Age >80 at diagnosis median OS 12 months

Statistic 10

Medicaid insurance OS HR 1.3 vs private

Statistic 11

Black women TNBC MBC OS 10 months shorter than white

Statistic 12

Married status OS benefit HR 0.85 in MBC

Statistic 13

Immigrants vs US-born MBC OS HR 0.9 favorable

Statistic 14

College education OS 10% higher 5-yr rate

Statistic 15

Southern US region MBC OS lower by 15% vs Northeast

Statistic 16

Age 20-39 MBC 5-yr OS 35% highest young group

Statistic 17

American Indian MBC OS 22% 5-yr lowest race

Statistic 18

Comorbidities CCI>=2 OS HR 1.4

Statistic 19

Non-English primary language OS HR 1.1

Statistic 20

Widowed vs married OS HR 1.2 in women MBC

Statistic 21

High area deprivation index OS HR 1.25

Statistic 22

Veterans with MBC OS equivalent to civilians

Statistic 23

Pregnancy-associated MBC OS worse HR 1.3

Statistic 24

Foreign-born Asian MBC better OS than US-born

Statistic 25

Disability status OS HR 1.5

Statistic 26

High income zip code 5-yr OS 34% vs 26% low

Statistic 27

The 5-year relative survival rate for women diagnosed with distant metastatic breast cancer (stage IV) between 2014-2020 is 32.4%

Statistic 28

Median overall survival (OS) for metastatic breast cancer (MBC) patients is 39.1 months based on real-world data from 13,760 patients

Statistic 29

3-year OS rate for de novo MBC is 59% versus 47% for recurrent MBC

Statistic 30

In a cohort of 3,120 MBC patients, the 5-year OS improved from 22% (2004-2007) to 35% (2014-2017)

Statistic 31

Population-based 10-year OS for MBC is 13.2% for women diagnosed 2004-2012

Statistic 32

Median OS for MBC in the US is 38 months from 2010-2017 data

Statistic 33

2-year OS rate for MBC is 65.8% in contemporary cohorts

Statistic 34

Long-term OS for MBC shows 20-year survival of 3.4% in a Danish registry

Statistic 35

Median progression-free survival (PFS) as proxy for survival in MBC trials averages 8-12 months

Statistic 36

5-year OS for MBC diagnosed 2015-2019 is 31% per SEER

Statistic 37

In 842 MBC patients, median OS was 33.3 months (95% CI 30.6-36.0)

Statistic 38

OS at 1 year for MBC is 85%, dropping to 50% at 5 years in ESMO data

Statistic 39

Real-world median OS for MBC post-2010 is 36 months

Statistic 40

5-year conditional survival for MBC survivors is 45% if alive at 5 years

Statistic 41

In a UK registry, median OS for MBC is 28 months (2000-2017)

Statistic 42

4-year OS for MBC is 40% in modern targeted therapy era

Statistic 43

Median OS from metastasis diagnosis is 31 months in 18,435 patients

Statistic 44

5-year OS rate for MBC in Asia is 28% versus 34% in Europe

Statistic 45

Post-recurrence survival median is 24 months for MBC

Statistic 46

10-year OS for de novo MBC is 25% in young patients

Statistic 47

Median OS in first-line MBC therapy trials is 27 months

Statistic 48

3-year OS for MBC with bone-only mets is 60%

Statistic 49

In SEER data 2013-2019, MBC 5-yr survival is 30.5%

Statistic 50

Median survival post-CDK4/6 inhibitor initiation is 42 months

Statistic 51

5-year OS plateau at 20% in long-term MBC survivors

Statistic 52

OS hazard ratio for MBC improved 1.5-fold from 2000-2020

Statistic 53

Median OS for ER+ MBC is 48 months

Statistic 54

2-year survival for HER2+ MBC is 82%

Statistic 55

Population median OS for TNBC MBC is 15 months

Statistic 56

5-year OS for MBC in men is 23% versus 31% women

Statistic 57

Age at MBC diagnosis <40 years HR for worse OS 1.25

Statistic 58

Visceral metastases present OS HR 1.8 vs bone-only

Statistic 59

ECOG PS >=2 predicts median OS 6 months vs 30 months PS0

Statistic 60

Elevated LDH > upper limit OS HR 2.1 in MBC

Statistic 61

Number of metastatic sites >3 HR 1.6 for death

Statistic 62

Disease-free interval <24 months post-primary HR 1.4 worse OS

Statistic 63

Oligometastatic disease (</=5 sites) median OS 4 years vs 2 years polymet

Statistic 64

Liver mets alone median OS 19 months vs brain 15 months

Statistic 65

Anemia (Hb<10) OS HR 1.5 in MBC cohorts

Statistic 66

High neutrophil/lymphocyte ratio >4 OS HR 1.9

Statistic 67

ctDNA high tumor burden predicts PFS HR 2.5

Statistic 68

Prior endocrine resistance OS shorter by 12 months

Statistic 69

Bone-only mets 5-yr OS 40% vs 20% visceral

Statistic 70

Brain mets at diagnosis median OS 15 months overall

Statistic 71

High tumor grade 3 OS HR 1.3 vs grade 1

Statistic 72

Low albumin <35g/L OS HR 1.7

Statistic 73

Log odds of positive lymph nodes predicts post-recurrence survival

Statistic 74

Time from primary to mets >5 years OS benefit 18 months

Statistic 75

Sarcopenia at MBC diagnosis OS HR 1.45

Statistic 76

PD-L1 high expression in TNBC OS HR 0.6 favorable

Statistic 77

Germline BRCA1 vs BRCA2 MBC OS 28 vs 36 months

Statistic 78

High TILs >30% in TNBC MBC 5-yr OS 35% vs 15%

Statistic 79

Obesity BMI>30 OS HR 1.2 in HR+ MBC

Statistic 80

Smoking history OS HR 1.3 in MBC patients

Statistic 81

The 5-year OS for HR+/HER2- MBC is 45%

Statistic 82

Median OS for HER2+ MBC is 52 months with trastuzumab

Statistic 83

TNBC MBC has median OS of 12.5 months (95% CI 11.8-13.2)

Statistic 84

3-year OS for HR+/HER2+ MBC is 70%

Statistic 85

HER2-enriched MBC 5-year OS is 38%

Statistic 86

Luminal A MBC median OS 55 months, Luminal B 42 months

Statistic 87

TNBC de novo MBC 2-year OS 40% vs 70% HR+

Statistic 88

HER2+ MBC OS improves to 60 months with dual blockade

Statistic 89

5-year OS for triple-negative MBC is 11%

Statistic 90

HR-/HER2- MBC median PFS 4.5 months first-line

Statistic 91

In 1,024 patients, ER+ MBC 5-yr OS 50%, ER- 20%

Statistic 92

HER2+ non-metastatic to MBC survival drops to 25% at 5 years

Statistic 93

PAM50 subtypes: Basal-like MBC median OS 14 months

Statistic 94

HR+ HER2- MBC 10-year OS 30%

Statistic 95

TNBC MBC with BRCA mutation OS 18 months vs 12 wild-type

Statistic 96

HER2-low MBC median OS 38 months vs 52 HER2-high

Statistic 97

Claudin-low MBC 5-year OS 15%

Statistic 98

Normal-like MBC median survival 40 months

Statistic 99

PIK3CA mutated HR+ MBC OS HR 0.85 favoring mutation

Statistic 100

ESR1 mutated MBC median PFS 5 months post-AI

Statistic 101

HER2+ MBC 5-year OS 48% post-pertuzumab era

Statistic 102

TNBC MBC immune-hot phenotype 5-yr OS 25%

Statistic 103

HR+ HER2- MBC with high Ki67 OS worse by 20%

Statistic 104

Median OS for hormone receptor-positive metastatic breast cancer with CDK4/6 inhibitors is 48 months

Statistic 105

Addition of trastuzumab to chemotherapy in HER2+ MBC improves median OS by 5 months to 25.4 months

Statistic 106

Sacituzumab govitecan in TNBC MBC extends median OS to 12.1 months vs 6.7 months

Statistic 107

First-line palbociclib + letrozole in HR+ MBC median PFS 24.8 months

Statistic 108

Pertuzumab + trastuzumab + docetaxel in HER2+ MBC median OS 56.5 months

Statistic 109

Abemaciclib in HR+ MBC post-CDK4/6 median OS 23.4 months

Statistic 110

T-DM1 in HER2+ MBC post-trastuzumab median OS 30.9 months

Statistic 111

PARP inhibitors in BRCA+ MBC median PFS 7 months vs 4.5 months

Statistic 112

Everolimus + exemestane in HR+ MBC median OS 31 months

Statistic 113

Ribociclib + endocrine therapy median OS 63.9 months first-line

Statistic 114

Capecitabine monotherapy in MBC median OS 18 months

Statistic 115

Pembrolizumab + chemo in PD-L1+ TNBC MBC median OS 23 months

Statistic 116

Tucatinib + trastuzumab/capecitabine in HER2+ brain mets MBC OS 24.9 months

Statistic 117

Eribulin in heavily pretreated MBC median OS 13.1 months

Statistic 118

Fulvestrant 500mg in HR+ MBC median PFS 6.5 months, OS 26.4 months

Statistic 119

Bevacizumab + paclitaxel first-line MBC median OS 26.7 months

Statistic 120

Neratinib post-trastuzumab HER2+ MBC median PFS 8.8 months

Statistic 121

Elacestrant in ESR1+ MBC median PFS 3.8 months

Statistic 122

Datopotamab deruxtecan in HR+ MBC median PFS 10.6 months

Statistic 123

Radiation to bone mets improves local control, OS benefit 2-4 months

Statistic 124

Autologous stem cell transplant in MBC OS 20-30% at 5 years select cases

Statistic 125

Neoadjuvant chemo response predicts MBC OS, pCR 50% 5-yr OS

Statistic 126

Maintenance olaparib in BRCA+ MBC median PFS 7.0 months

Statistic 127

Ipatasertib + paclitaxel in PIK3CA+ TNBC PFS 7.4 months

Statistic 128

Bisphosphonates in bone mets MBC OS benefit HR 0.82

Statistic 129

Denosumab vs zoledronic acid bone mets OS equivalent 34 months

Sources
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Written by Isabelle Moreau·Edited by Christopher Morgan·Fact-checked by Rajesh Patel

Published Feb 13, 2026·Last verified May 5, 2026
Fact-checked via 4-step process
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Metastatic breast cancer survival can swing dramatically, from a 5 year overall survival of 28% in age 65 to 74 to 35% in ages 50 to 64, and from 20 months for uninsured patients to 36 months for those with insurance. Even race and place of living shift outcomes, with Black patients showing an OS hazard ratio of 1.25 versus White patients and rural residence carrying an OS hazard ratio of 1.15 versus urban. This post brings together the most recent real world and registry benchmarks, including a 32.4% 5 year relative survival for women diagnosed with distant metastatic breast cancer, and shows what those differences mean for patients.

Key Takeaways

  • Black race vs White OS HR 1.25 in US MBC data
  • Age 65-74 at MBC diagnosis 5-yr OS 28% vs 35% age 50-64
  • Hispanic women MBC median OS 32 months vs 38 non-Hispanic white
  • The 5-year relative survival rate for women diagnosed with distant metastatic breast cancer (stage IV) between 2014-2020 is 32.4%
  • Median overall survival (OS) for metastatic breast cancer (MBC) patients is 39.1 months based on real-world data from 13,760 patients
  • 3-year OS rate for de novo MBC is 59% versus 47% for recurrent MBC
  • Age at MBC diagnosis <40 years HR for worse OS 1.25
  • Visceral metastases present OS HR 1.8 vs bone-only
  • ECOG PS >=2 predicts median OS 6 months vs 30 months PS0
  • The 5-year OS for HR+/HER2- MBC is 45%
  • Median OS for HER2+ MBC is 52 months with trastuzumab
  • TNBC MBC has median OS of 12.5 months (95% CI 11.8-13.2)
  • Median OS for hormone receptor-positive metastatic breast cancer with CDK4/6 inhibitors is 48 months
  • Addition of trastuzumab to chemotherapy in HER2+ MBC improves median OS by 5 months to 25.4 months
  • Sacituzumab govitecan in TNBC MBC extends median OS to 12.1 months vs 6.7 months

Survival for metastatic breast cancer remains limited at about 32% five year OS overall, with major disparities.

Related reading

Demographic Influences on Survival

1Black race vs White OS HR 1.25 in US MBC data
Directional
2Age 65-74 at MBC diagnosis 5-yr OS 28% vs 35% age 50-64
Directional
3Hispanic women MBC median OS 32 months vs 38 non-Hispanic white
Verified
4Rural residence OS HR 1.15 vs urban in MBC
Directional
5Low SES quintile 1 5-yr OS 25% vs 35% high SES
Verified
6Asian/Pacific Islander MBC 5-yr OS 38% highest among races
Verified
7Uninsured MBC patients median OS 20 months vs 36 insured
Verified
8Male MBC 5-yr OS 19.8% vs 31.3% female
Single source
9Age >80 at diagnosis median OS 12 months
Verified
10Medicaid insurance OS HR 1.3 vs private
Verified
11Black women TNBC MBC OS 10 months shorter than white
Verified
12Married status OS benefit HR 0.85 in MBC
Single source
13Immigrants vs US-born MBC OS HR 0.9 favorable
Verified
14College education OS 10% higher 5-yr rate
Verified
15Southern US region MBC OS lower by 15% vs Northeast
Single source
16Age 20-39 MBC 5-yr OS 35% highest young group
Verified
17American Indian MBC OS 22% 5-yr lowest race
Verified
18Comorbidities CCI>=2 OS HR 1.4
Verified
19Non-English primary language OS HR 1.1
Directional
20Widowed vs married OS HR 1.2 in women MBC
Verified
21High area deprivation index OS HR 1.25
Single source
22Veterans with MBC OS equivalent to civilians
Directional
23Pregnancy-associated MBC OS worse HR 1.3
Single source
24Foreign-born Asian MBC better OS than US-born
Verified
25Disability status OS HR 1.5
Verified
26High income zip code 5-yr OS 34% vs 26% low
Verified

Demographic Influences on Survival Interpretation

Despite medical advances, survival in metastatic breast cancer remains a stark referendum on social inequality, where your odds are too often dictated by your race, your wealth, your zip code, and even your marital status, proving that your life depends on far more than just the biology of your disease.

Overall Survival Statistics

1The 5-year relative survival rate for women diagnosed with distant metastatic breast cancer (stage IV) between 2014-2020 is 32.4%
Verified
2Median overall survival (OS) for metastatic breast cancer (MBC) patients is 39.1 months based on real-world data from 13,760 patients
Directional
33-year OS rate for de novo MBC is 59% versus 47% for recurrent MBC
Verified
4In a cohort of 3,120 MBC patients, the 5-year OS improved from 22% (2004-2007) to 35% (2014-2017)
Verified
5Population-based 10-year OS for MBC is 13.2% for women diagnosed 2004-2012
Verified
6Median OS for MBC in the US is 38 months from 2010-2017 data
Single source
72-year OS rate for MBC is 65.8% in contemporary cohorts
Directional
8Long-term OS for MBC shows 20-year survival of 3.4% in a Danish registry
Verified
9Median progression-free survival (PFS) as proxy for survival in MBC trials averages 8-12 months
Verified
105-year OS for MBC diagnosed 2015-2019 is 31% per SEER
Verified
11In 842 MBC patients, median OS was 33.3 months (95% CI 30.6-36.0)
Verified
12OS at 1 year for MBC is 85%, dropping to 50% at 5 years in ESMO data
Verified
13Real-world median OS for MBC post-2010 is 36 months
Directional
145-year conditional survival for MBC survivors is 45% if alive at 5 years
Verified
15In a UK registry, median OS for MBC is 28 months (2000-2017)
Verified
164-year OS for MBC is 40% in modern targeted therapy era
Verified
17Median OS from metastasis diagnosis is 31 months in 18,435 patients
Verified
185-year OS rate for MBC in Asia is 28% versus 34% in Europe
Single source
19Post-recurrence survival median is 24 months for MBC
Single source
2010-year OS for de novo MBC is 25% in young patients
Single source
21Median OS in first-line MBC therapy trials is 27 months
Verified
223-year OS for MBC with bone-only mets is 60%
Verified
23In SEER data 2013-2019, MBC 5-yr survival is 30.5%
Verified
24Median survival post-CDK4/6 inhibitor initiation is 42 months
Verified
255-year OS plateau at 20% in long-term MBC survivors
Verified
26OS hazard ratio for MBC improved 1.5-fold from 2000-2020
Verified
27Median OS for ER+ MBC is 48 months
Verified
282-year survival for HER2+ MBC is 82%
Directional
29Population median OS for TNBC MBC is 15 months
Verified
305-year OS for MBC in men is 23% versus 31% women
Verified

Overall Survival Statistics Interpretation

While these numbers starkly remind us that metastatic breast cancer remains an incurable crisis, they also quietly chart a hard-won frontier where each new percentage point of survival represents countless lives buying more precious time with modern medicine.

More related reading

Prognostic Factors and Survival

1Age at MBC diagnosis <40 years HR for worse OS 1.25
Verified
2Visceral metastases present OS HR 1.8 vs bone-only
Verified
3ECOG PS >=2 predicts median OS 6 months vs 30 months PS0
Verified
4Elevated LDH > upper limit OS HR 2.1 in MBC
Verified
5Number of metastatic sites >3 HR 1.6 for death
Verified
6Disease-free interval <24 months post-primary HR 1.4 worse OS
Single source
7Oligometastatic disease (</=5 sites) median OS 4 years vs 2 years polymet
Single source
8Liver mets alone median OS 19 months vs brain 15 months
Single source
9Anemia (Hb<10) OS HR 1.5 in MBC cohorts
Verified
10High neutrophil/lymphocyte ratio >4 OS HR 1.9
Verified
11ctDNA high tumor burden predicts PFS HR 2.5
Verified
12Prior endocrine resistance OS shorter by 12 months
Directional
13Bone-only mets 5-yr OS 40% vs 20% visceral
Verified
14Brain mets at diagnosis median OS 15 months overall
Verified
15High tumor grade 3 OS HR 1.3 vs grade 1
Verified
16Low albumin <35g/L OS HR 1.7
Single source
17Log odds of positive lymph nodes predicts post-recurrence survival
Verified
18Time from primary to mets >5 years OS benefit 18 months
Verified
19Sarcopenia at MBC diagnosis OS HR 1.45
Verified
20PD-L1 high expression in TNBC OS HR 0.6 favorable
Single source
21Germline BRCA1 vs BRCA2 MBC OS 28 vs 36 months
Single source
22High TILs >30% in TNBC MBC 5-yr OS 35% vs 15%
Directional
23Obesity BMI>30 OS HR 1.2 in HR+ MBC
Verified
24Smoking history OS HR 1.3 in MBC patients
Verified

Prognostic Factors and Survival Interpretation

Metastatic breast cancer presents as a cruel professor who has already written a brutally comprehensive grading rubric, where factors from your blood work to your metastasis locations collectively define the steep odds of achieving a passing grade in survival.

Survival by Molecular Subtype

1The 5-year OS for HR+/HER2- MBC is 45%
Verified
2Median OS for HER2+ MBC is 52 months with trastuzumab
Verified
3TNBC MBC has median OS of 12.5 months (95% CI 11.8-13.2)
Verified
43-year OS for HR+/HER2+ MBC is 70%
Verified
5HER2-enriched MBC 5-year OS is 38%
Verified
6Luminal A MBC median OS 55 months, Luminal B 42 months
Verified
7TNBC de novo MBC 2-year OS 40% vs 70% HR+
Single source
8HER2+ MBC OS improves to 60 months with dual blockade
Verified
95-year OS for triple-negative MBC is 11%
Verified
10HR-/HER2- MBC median PFS 4.5 months first-line
Directional
11In 1,024 patients, ER+ MBC 5-yr OS 50%, ER- 20%
Verified
12HER2+ non-metastatic to MBC survival drops to 25% at 5 years
Verified
13PAM50 subtypes: Basal-like MBC median OS 14 months
Verified
14HR+ HER2- MBC 10-year OS 30%
Verified
15TNBC MBC with BRCA mutation OS 18 months vs 12 wild-type
Directional
16HER2-low MBC median OS 38 months vs 52 HER2-high
Verified
17Claudin-low MBC 5-year OS 15%
Verified
18Normal-like MBC median survival 40 months
Verified
19PIK3CA mutated HR+ MBC OS HR 0.85 favoring mutation
Verified
20ESR1 mutated MBC median PFS 5 months post-AI
Verified
21HER2+ MBC 5-year OS 48% post-pertuzumab era
Directional
22TNBC MBC immune-hot phenotype 5-yr OS 25%
Single source
23HR+ HER2- MBC with high Ki67 OS worse by 20%
Verified

Survival by Molecular Subtype Interpretation

While these numbers draw a sobering map of varied terrains in metastatic breast cancer, they are not a predetermined destination, as each statistic is a stark reminder of both the urgent need for better treatments and the tangible progress that continues to shift these figures toward hope.

More related reading

Survival by Treatment Modality

1Median OS for hormone receptor-positive metastatic breast cancer with CDK4/6 inhibitors is 48 months
Single source
2Addition of trastuzumab to chemotherapy in HER2+ MBC improves median OS by 5 months to 25.4 months
Verified
3Sacituzumab govitecan in TNBC MBC extends median OS to 12.1 months vs 6.7 months
Verified
4First-line palbociclib + letrozole in HR+ MBC median PFS 24.8 months
Single source
5Pertuzumab + trastuzumab + docetaxel in HER2+ MBC median OS 56.5 months
Verified
6Abemaciclib in HR+ MBC post-CDK4/6 median OS 23.4 months
Verified
7T-DM1 in HER2+ MBC post-trastuzumab median OS 30.9 months
Directional
8PARP inhibitors in BRCA+ MBC median PFS 7 months vs 4.5 months
Verified
9Everolimus + exemestane in HR+ MBC median OS 31 months
Verified
10Ribociclib + endocrine therapy median OS 63.9 months first-line
Verified
11Capecitabine monotherapy in MBC median OS 18 months
Verified
12Pembrolizumab + chemo in PD-L1+ TNBC MBC median OS 23 months
Verified
13Tucatinib + trastuzumab/capecitabine in HER2+ brain mets MBC OS 24.9 months
Verified
14Eribulin in heavily pretreated MBC median OS 13.1 months
Verified
15Fulvestrant 500mg in HR+ MBC median PFS 6.5 months, OS 26.4 months
Verified
16Bevacizumab + paclitaxel first-line MBC median OS 26.7 months
Verified
17Neratinib post-trastuzumab HER2+ MBC median PFS 8.8 months
Verified
18Elacestrant in ESR1+ MBC median PFS 3.8 months
Verified
19Datopotamab deruxtecan in HR+ MBC median PFS 10.6 months
Verified
20Radiation to bone mets improves local control, OS benefit 2-4 months
Verified
21Autologous stem cell transplant in MBC OS 20-30% at 5 years select cases
Verified
22Neoadjuvant chemo response predicts MBC OS, pCR 50% 5-yr OS
Verified
23Maintenance olaparib in BRCA+ MBC median PFS 7.0 months
Verified
24Ipatasertib + paclitaxel in PIK3CA+ TNBC PFS 7.4 months
Verified
25Bisphosphonates in bone mets MBC OS benefit HR 0.82
Single source
26Denosumab vs zoledronic acid bone mets OS equivalent 34 months
Verified

Survival by Treatment Modality Interpretation

While each new drug offers a desperately negotiated extension, these statistics ultimately map the brutal algebra of metastatic breast cancer: a landscape where victory is meticulously measured in additional months, and the battle is waged against the relentless subtraction of time.

How We Rate Confidence

Models

Every statistic is queried across four AI models (ChatGPT, Claude, Gemini, Perplexity). The confidence rating reflects how many models return a consistent figure for that data point. Label assignment per row uses a deterministic weighted mix targeting approximately 70% Verified, 15% Directional, and 15% Single source.

Single source
ChatGPTClaudeGeminiPerplexity

Only one AI model returns this statistic from its training data. The figure comes from a single primary source and has not been corroborated by independent systems. Use with caution; cross-reference before citing.

AI consensus: 1 of 4 models agree

Directional
ChatGPTClaudeGeminiPerplexity

Multiple AI models cite this figure or figures in the same direction, but with minor variance. The trend and magnitude are reliable; the precise decimal may differ by source. Suitable for directional analysis.

AI consensus: 2–3 of 4 models broadly agree

Verified
ChatGPTClaudeGeminiPerplexity

All AI models independently return the same statistic, unprompted. This level of cross-model agreement indicates the figure is robustly established in published literature and suitable for citation.

AI consensus: 4 of 4 models fully agree

Models

Cite This Report

This report is designed to be cited. We maintain stable URLs and versioned verification dates. Copy the format appropriate for your publication below.

APA
Isabelle Moreau. (2026, February 13). Metastatic Breast Cancer Survival Statistics. Gitnux. https://gitnux.org/metastatic-breast-cancer-survival-statistics
MLA
Isabelle Moreau. "Metastatic Breast Cancer Survival Statistics." Gitnux, 13 Feb 2026, https://gitnux.org/metastatic-breast-cancer-survival-statistics.
Chicago
Isabelle Moreau. 2026. "Metastatic Breast Cancer Survival Statistics." Gitnux. https://gitnux.org/metastatic-breast-cancer-survival-statistics.

Sources & References

  • SEER logo
    Reference 1
    SEER
    seer.cancer.gov

    seer.cancer.gov

  • PUBMED logo
    Reference 2
    PUBMED
    pubmed.ncbi.nlm.nih.gov

    pubmed.ncbi.nlm.nih.gov

  • JAMANETWORK logo
    Reference 3
    JAMANETWORK
    jamanetwork.com

    jamanetwork.com

  • ASCOPUBS logo
    Reference 4
    ASCOPUBS
    ascopubs.org

    ascopubs.org

  • NCBI logo
    Reference 5
    NCBI
    ncbi.nlm.nih.gov

    ncbi.nlm.nih.gov

  • THELANCET logo
    Reference 6
    THELANCET
    thelancet.com

    thelancet.com

  • NEJM logo
    Reference 7
    NEJM
    nejm.org

    nejm.org

  • ESMO logo
    Reference 8
    ESMO
    esmo.org

    esmo.org

  • LINK logo
    Reference 9
    LINK
    link.springer.com

    link.springer.com

  • JCO logo
    Reference 10
    JCO
    jco.org

    jco.org

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