Key Takeaways
- Up to 30% of LASIK patients develop dry eye syndrome postoperatively, with symptoms persisting beyond 6 months in 20% of cases
- Postoperative dry eye occurs in 20-50% of LASIK patients, linked to nerve damage from flap creation
- 95% of patients report dry eye symptoms at 1 week post-LASIK, dropping to 40% at 6 months
- Halos affect 42% of patients at night 6 months post-LASIK
- Glare disability scores increase by 50% in low light post-LASIK
- Starbursts reported by 35% of patients driving at night after LASIK
- Corneal ectasia develops in 0.04-2.8% of LASIK cases
- Flap dislocation occurs in 1-5% within first 24 hours post-LASIK
- Diffuse lamellar keratitis (DLK) stage 2+ in 0.6-2.3% of procedures
- Infection rate 1/5000 LASIK procedures overall
- Sterile inflammation (SLE) in 0.1%
- Severe pain unresponsive to meds in 1-2% first night post-LASIK
- 20-30% regression within 5 years requiring enhancement
- 46% patient dissatisfaction with vision at 3 months in some studies
- 10-15% need retreatment for undercorrection/overcorrection
Dry eye is the most common and often long lasting risk from Lasik surgery.
Corneal Ectasia and Flap Complications
- Corneal ectasia develops in 0.04-2.8% of LASIK cases
- Flap dislocation occurs in 1-5% within first 24 hours post-LASIK
- Diffuse lamellar keratitis (DLK) stage 2+ in 0.6-2.3% of procedures
- Buttonhole flaps happen in 0.5-2% of microkeratome LASIK cases
- Free cap loss in 0.08-1.5% during flap lifting
- Epithelial ingrowth under flap in 1-15%, symptomatic in 0.5-5%
- Postoperative ectasia risk 1:625 in screened patients, higher unscreened
- Flap striae requiring lifting in 1.5-4% of cases
- Central toxic keratopathy in 0.03%, leading to vision loss
- Interface fluid syndrome from steroid use in 2-5% post-LASIK
- Decentered flaps in 0.2-1% with femtosecond lasers
- Ectasia after high myopia LASIK in 1/200 cases
- Sloughing of epithelium over flap in 0.1-1%
- Pressure-induced stromal keratitis in 0.3%
- Irregular flap thickness >20μm variance in 5% microkeratome cases
- Late ectasia onset 5-10 years post-LASIK in 0.1%
- Flap melt from infection in 0.02%
- 2.0% ectasia rate in forme fruste keratoconus undetected pre-op
- Haze grade 2+ in 1.2% post-LASIK
- Flap hinge tear in 0.4% during enhancement
- Recurrent epithelial erosion syndrome in 0.6% post-flap
- Keratoconus progression masked post-LASIK in 0.5%
- Flap-related astigmatism >1D in 0.8%
- Microbial keratitis under flap 1:3000 cases
Corneal Ectasia and Flap Complications Interpretation
Dry Eye and Ocular Surface Issues
- Up to 30% of LASIK patients develop dry eye syndrome postoperatively, with symptoms persisting beyond 6 months in 20% of cases
- Postoperative dry eye occurs in 20-50% of LASIK patients, linked to nerve damage from flap creation
- 95% of patients report dry eye symptoms at 1 week post-LASIK, dropping to 40% at 6 months
- LASIK induces neurotrophic keratopathy in 25-60% of cases, leading to severe dry eye
- Chronic dry eye after LASIK affects 17% of patients at 5 years follow-up
- Meibomian gland dysfunction increases by 69% post-LASIK, contributing to evaporative dry eye
- 28% of LASIK patients require artificial tears for over 1 year due to persistent dry eye
- Dry eye disease severity scores double within 3 months post-LASIK in 35% of patients
- 11-20% of patients discontinue contact lens wear pre-LASIK but develop worse dry eye post-op
- Tear breakup time decreases by 50% in 40% of LASIK patients at 3 months
- Schirmer test values drop below 5mm in 23% of patients 6 months after LASIK
- Hyperosmolarity in tears post-LASIK exceeds 316 mOsm/L in 31% of cases at 1 month
- Lid margin disease worsens in 45% of myopic LASIK patients within 1 year
- Corneal sensation reduces by 80% at 1 month, recovering partially in only 60% by 12 months
- 15% of LASIK patients report severe dry eye impacting quality of life at 2 years
- 22% incidence of filamentary keratitis due to dry eye post-LASIK
- Goblet cell density decreases by 30% post-LASIK, leading to mucin deficiency dry eye
- 36% of patients need punctal plugs for dry eye management after LASIK
- Dry eye symptoms correlate with higher-order aberrations increase in 27% of cases
- Post-LASIK dry eye recurs in 18% despite pre-op treatment
- 41% of hyperopes develop worse dry eye than myopes post-LASIK
- Ocular surface disease index scores rise 25 points on average post-LASIK in symptomatic patients
- 12% require cyclosporine drops long-term for dry eye after LASIK
- Epithelial basement membrane dystrophy linked to dry eye in 9% post-LASIK
- 33% show reduced corneal nerve density at 12 months, perpetuating dry eye
- Blepharitis incidence jumps to 52% within 6 months post-LASIK
- 19% of patients have delayed dry eye onset at 1-2 years post-op
- Tear film lipid layer thickness halves in 38% of LASIK patients
- 24% report burning sensation from dry eye persisting >3 months
- Aqueous deficiency dry eye in 14% confirmed by low Schirmer II test
Dry Eye and Ocular Surface Issues Interpretation
Infection, Inflammation, and Pain
- Infection rate 1/5000 LASIK procedures overall
- Sterile inflammation (SLE) in 0.1%
- Severe pain unresponsive to meds in 1-2% first night post-LASIK
- Endophthalmitis risk 1:10,000 post-LASIK
- Herpes simplex keratitis reactivation 1:500
- DLK stage 4 (necrotizing) 0.01%
- Photophobia severe in 15% at day 1
- Uveitis post-LASIK 0.03%
- Pain score >7/10 in 0.5% beyond 48 hours
- Fungal keratitis 1:20,000
- Interface abscess 0.05%
- Marginal keratitis 0.2%
- Severe foreign body sensation in 3% day 1
- Scleritis rare 0.001%
- Retinal detachment risk increases 1.36x post-LASIK
- Inflammation grade 3+ in 0.4% femtosecond LASIK
- Neuropathic pain chronic in 2-5%
- Bleb leak post-LASIK in glaucoma patients 0.1%
- 8% report moderate-severe pain at 1 week
- Acanthamoeba keratitis rare 1:10 million
- Central island formation inflammatory in 0.3%
- Iritis 0.05%
- Chronic irritation 4% at 3 months
Infection, Inflammation, and Pain Interpretation
Night Vision and Visual Quality Problems
- Halos affect 42% of patients at night 6 months post-LASIK
- Glare disability scores increase by 50% in low light post-LASIK
- Starbursts reported by 35% of patients driving at night after LASIK
- Higher-order aberrations (HOAs) rise 200-300% post-LASIK, causing visual disturbances in 28%
- Contrast sensitivity loss at 18 cpd in 31% of patients 1 year post-op
- Double vision occurs in 1-5% due to irregular astigmatism post-LASIK
- 20% experience persistent halos/glare at 5 years
- Spherical aberration increases by 0.3 μm in 40% of 6mm pupils post-LASIK
- Night myopia induced in 15% of emmetropic patients post-LASIK
- 27% report reduced night vision quality impacting daily activities
- Coma aberrations double post-LASIK, affecting 22% severely
- Ghosting images in 12% due to decentered ablation
- 18% have modulation transfer function drop >20% at night
- Trefoil aberrations increase 150% in 25% of hyperopic LASIK cases
- 33% of large pupil patients (>6mm) suffer severe glare/halos
- Visual acuity drops 2 lines in mesopic conditions for 16% post-LASIK
- 21% report monocular diplopia persisting >6 months
- Strehl ratio decreases to <0.2 in 29% under low light post-op
- 14% experience positive dysphotopsia lasting 1 year
- Point spread function broadens 40% in 23% of patients at night
- 30% have halo size >30 arcmin in simulated night driving
- Tetrafocal halos in 17% due to multifocal ablation profiles
- 19% show reduced scotopic pupil function post-LASIK
- Glare recovery incomplete in 26% at 24 months
- 11% require PRK enhancement for HOA-related night issues
Night Vision and Visual Quality Problems Interpretation
Regression, Enhancement, and Patient Outcomes
- 20-30% regression within 5 years requiring enhancement
- 46% patient dissatisfaction with vision at 3 months in some studies
- 10-15% need retreatment for undercorrection/overcorrection
- Loss of 2+ lines BCVA in 1-5% long-term
- 25% report suboptimal satisfaction due to side effects
- Myopic regression 0.23D/year average in high myopia
- 12% enhancement rate at 10 years follow-up
- 5.5% lose spectacle independence long-term
- NEI VFQ-25 scores drop 10 points in 18% dissatisfied patients
- Hyperopic shift 1% per year in 8% post-LASIK
- 35% of patients over 40 need reading glasses post-presbyopic LASIK
- Induced astigmatism >0.5D in 4.5%
- 28% report "not worth it" in anonymous surveys
- Retreatment success 85% but 3% need multiple
- 2% develop ectasia requiring CXL
- Patient regret 4-10% in large cohorts
- 15% undercorrected by >1D initially
- Quality of life impact high in 7% due to halos/regression
- 22% enhancement for high myopes (> -6D)
- BCVA worse than pre-op in 2.2% at 6 months
- 9% report new glasses dependence post-LASIK
- Satisfaction <80% in 13% of patients over 50
- Regression >1D in 6% within 2 years
Regression, Enhancement, and Patient Outcomes Interpretation
Sources & References
- Reference 1NCBIncbi.nlm.nih.govVisit source
- Reference 2PUBMEDpubmed.ncbi.nlm.nih.govVisit source
- Reference 3AOAaoa.orgVisit source
- Reference 4IOVSiovs.arvojournals.orgVisit source
- Reference 5JAMANETWORKjamanetwork.comVisit source
- Reference 6REVIEWOFOPTOMETRYreviewofoptometry.comVisit source
- Reference 7EYEWIKIeyewiki.aao.orgVisit source
- Reference 8JCRSJOURNALjcrsjournal.orgVisit source
- Reference 9REVIEWOFOPHTHALMOLOGYreviewofophthalmology.comVisit source
- Reference 10FDAfda.govVisit source






