Key Takeaways
- In 2021, approximately 1.1 million people aged 12 or older in the United States reported using heroin in the past year
- Heroin use in the past month among U.S. adults aged 18-25 was reported at 0.2% in 2020, equating to about 72,000 individuals
- Globally, an estimated 10.1 million people used opioids including heroin in 2019
- Heroin use past year in U.S. males aged 12+ was 0.5% in 2021 vs 0.2% females
- Among U.S. adults 18-25, 0.3% males and 0.1% females used heroin past year in 2021
- Non-Hispanic whites had a 0.4% past-year heroin use rate in U.S. 2021, highest among races
- In 2021, heroin-involved overdose deaths in U.S. totaled 14,716
- Heroin users have a 20-fold increased risk of overdose death compared to non-users
- 91% of U.S. opioid overdose deaths in 2021 involved fentanyl, often mixed with heroin
- In 2021, 25% of U.S. adults with heroin use disorder received treatment
- Methadone treatment retention for heroin dependence is 50% at 6 months
- Buprenorphine reduces heroin relapse by 50% in first year per trials
- Heroin trafficking costs U.S. $50 billion annually in enforcement and health
- U.S. heroin market value estimated at $27 billion per year in 2016
- Lifetime cost per heroin user to society is $1.5 million including crime
Despite treatment advances, heroin use remains a destructive and costly public health crisis.
Demographics
- Heroin use past year in U.S. males aged 12+ was 0.5% in 2021 vs 0.2% females
- Among U.S. adults 18-25, 0.3% males and 0.1% females used heroin past year in 2021
- Non-Hispanic whites had a 0.4% past-year heroin use rate in U.S. 2021, highest among races
- U.S. rural areas saw 0.5% past-year heroin use vs 0.3% urban in 2020 NSDUH data
- Among U.S. unemployed adults, past-year heroin use was 1.2% in 2021
- High school graduates had 0.4% heroin use past year vs 0.2% college grads in U.S. 2021
- In U.S., ages 26-34 had highest past-year heroin use at 0.6% in 2021
- U.S. males with income <$20k had 1.1% past-year heroin use in 2021
- Among U.S. AIAN population, past-year heroin use was 0.8% in 2021 NSDUH
- U.S. adults 18+ with mental illness had 0.9% past-year heroin use vs 0.2% without in 2021
- U.S. past-year heroin use among males 12+ was 0.6% vs 0.3% females in 2020
- Among U.S. 12-17 year olds, male heroin use past year 0.2% vs 0.1% female 2021
- Hispanic U.S. population had 0.3% past-year heroin use in 2021 NSDUH
- U.S. small metro areas reported 0.6% past-year heroin use in 2021
- Full-time employed U.S. adults had 0.2% heroin use vs 1.0% unemployed 2021
- U.S. high school dropouts had 0.8% past-year heroin use in 2021
- Ages 35-49 in U.S. had 0.5% past-year heroin use rate 2021
- Low-income (<$20k) U.S. females had 0.7% past-year heroin use 2021
- Black non-Hispanic U.S. adults had 0.2% past-year heroin use 2021
- U.S. adults with depression had 1.5% past-year heroin use vs 0.1% without 2021
Demographics Interpretation
Economic and Legal Impacts
- Heroin trafficking costs U.S. $50 billion annually in enforcement and health
- U.S. heroin market value estimated at $27 billion per year in 2016
- Lifetime cost per heroin user to society is $1.5 million including crime
- 80% of heroin enters U.S. via Mexico border per DEA 2021
- U.S. incarcerations for heroin possession: 100,000 annually pre-2020 reforms
- Workplace productivity loss from heroin: $20 billion yearly in U.S.
- Heroin-related crime costs U.S. cities $5-10 billion in policing yearly
- Global heroin production from Afghanistan: 480 tons in 2020
- U.S. societal cost of heroin use $78.5 billion annually incl crime/health 2017
- Heroin purity averaged 30% in U.S. street samples 2020 per DEA
- $150,000 average lifetime criminal justice cost per heroin offender
- 85% of U.S. heroin from Mexico per 2022 NDTA seizure data
- 50,000 U.S. state prison commitments for heroin offenses yearly avg 2015-19
- Absenteeism from heroin addiction costs U.S. employers $11 billion/year
- Heroin-related burglaries account for 20% of property crimes in some cities
- Afghanistan opium crop yielded 6,300 tons heroin potential in 2017 peak
- U.S. heroin import value $50 billion wholesale est. 2019
- Diversion of diverted prescription opioids to heroin markets 25% overlap
Economic and Legal Impacts Interpretation
Health and Mortality
- In 2021, heroin-involved overdose deaths in U.S. totaled 14,716
- Heroin users have a 20-fold increased risk of overdose death compared to non-users
- 91% of U.S. opioid overdose deaths in 2021 involved fentanyl, often mixed with heroin
- Heroin injection leads to HIV risk, with 9% prevalence among users in some U.S. studies
- Chronic heroin use causes respiratory depression in 50% of overdose cases
- U.S. heroin overdoses caused 15,469 deaths in 2019 per CDC WONDER
- Hepatitis C infection rate among heroin injectors is 50-90% lifetime
- Heroin withdrawal symptoms peak at 48-72 hours in 70% of users
- Endocarditis risk from IV heroin is 2-5% annually among users
- Nasal heroin use leads to sinusitis in 30% of chronic users per studies
- Heroin overdose deaths rose to 13,172 in U.S. 2020 per provisional data
- Heroin users face 50 times higher mortality risk from overdose than general pop
- 76% of 2021 U.S. synthetic opioid deaths involved heroin mixtures
- HCV prevalence among U.S. heroin injectors reached 67% in 2018 NHANES
- Heroin overdose causes hypoxic brain injury in 30% of survivors
- 36,000 U.S. heroin-related overdose deaths 2016-2020 cumulative
- HIV seroprevalence 15% among long-term heroin injectors in urban areas
- Heroin-induced pulmonary edema occurs in 50% of fatal overdoses autopsy
- Abscesses from skin popping heroin affect 25% of non-IV users yearly
- Chronic heroin use linked to 40% increased risk of stroke per cohort studies
Health and Mortality Interpretation
Prevalence and Incidence
- In 2021, approximately 1.1 million people aged 12 or older in the United States reported using heroin in the past year
- Heroin use in the past month among U.S. adults aged 18-25 was reported at 0.2% in 2020, equating to about 72,000 individuals
- Globally, an estimated 10.1 million people used opioids including heroin in 2019
- In the EU, heroin seizures accounted for 1,200 kg in 2020, indicating ongoing trafficking
- Past-year heroin initiation among U.S. youth aged 12-17 was 0.1% or 23,000 people in 2021
- Heroin use disorder affected 828,000 people aged 12+ in the U.S. in 2021
- In Australia, 1.2% of the population aged 14+ reported lifetime heroin use in 2019
- U.S. past-year heroin use among adults 26+ was 0.3% in 2021
- Worldwide, heroin accounts for 28% of opioid use disorders in 2020 estimates
- In Canada, 0.7% of Canadians aged 15+ reported past-year opioid use including heroin in 2019
- In 2021, approximately 1.2 million people aged 12 or older in the United States reported past-year heroin use, up slightly from 2020
- Heroin use in the past year among U.S. young adults (18-25) reached 0.3% or roughly 100,000 people in 2021
- An estimated 9.2 million people worldwide injected drugs including heroin in 2019
- In Europe, 1.3 million people were high-risk opioid users primarily heroin in 2020
- Past-year heroin use initiation among U.S. adults 18+ was 0.1% or 250,000 in 2021
- Heroin use disorder prevalence in U.S. was 0.3% or 828,000 aged 12+ in 2021
- In the UK, 1 in 1,000 adults used heroin in past year per 2019 Crime Survey
- U.S. past-year heroin use rate was 0.4% among adults 26+ in 2021
- Opioid use disorder globally affected 40 million, with heroin prominent in Asia 2020
- In Russia, 5.5% of adults reported lifetime heroin use in recent surveys
Prevalence and Incidence Interpretation
Treatment and Recovery
- In 2021, 25% of U.S. adults with heroin use disorder received treatment
- Methadone treatment retention for heroin dependence is 50% at 6 months
- Buprenorphine reduces heroin relapse by 50% in first year per trials
- U.S. opioid treatment programs admitted 475,000 patients in 2020, many for heroin
- Contingency management boosts heroin abstinence rates to 60% short-term
- 12-step programs show 20-30% long-term abstinence for heroin users
- Naltrexone implant reduces heroin use by 70% in Australian trials
- U.S. MAT for heroin increased 5-fold from 2002-2020 to 2 million patients
- Relapse within 1 month post-detox is 40-60% for heroin users
- Only 20% of U.S. heroin users with OUD received any specialty treatment 2021
- Heroin patients on methadone 1-year retention 55% vs 20% counseling only
- Extended-release naltrexone cuts heroin days used by 90% in 6 months trials
- 1.5 million U.S. specialty treatment slots needed for opioid incl heroin 2020
- Cognitive behavioral therapy reduces heroin use 50% in outpatient settings
- 40% of U.S. OTP patients were female heroin users in 2020 data
- First-year relapse rate post-MAT for heroin is 30-50% upon discontinuation
- Vivitrol monthly injections retain 70% heroin patients at 6 months
- Heroin emergency dept visits led to treatment referral in 25% cases 2019
- Peer recovery coaching improves 90-day heroin abstinence by 40%
Treatment and Recovery Interpretation
Sources & References
- Reference 1SAMHSAsamhsa.govVisit source
- Reference 2NIDAnida.nih.govVisit source
- Reference 3UNODCunodc.orgVisit source
- Reference 4EMCDDAemcdda.europa.euVisit source
- Reference 5AIHWaihw.gov.auVisit source
- Reference 6WHOwho.intVisit source
- Reference 7CANADAcanada.caVisit source
- Reference 8CDCcdc.govVisit source
- Reference 9NCBIncbi.nlm.nih.govVisit source
- Reference 10WONDERwonder.cdc.govVisit source
- Reference 11JAMANETWORKjamanetwork.comVisit source
- Reference 12NEJMnejm.orgVisit source
- Reference 13DPTdpt.samhsa.govVisit source
- Reference 14THELANCETthelancet.comVisit source
- Reference 15RANDrand.orgVisit source
- Reference 16DEAdea.govVisit source
- Reference 17SENTENCINGPROJECTsentencingproject.orgVisit source
- Reference 18OJPojp.govVisit source
- Reference 19GOVgov.ukVisit source
- Reference 20AHAJOURNALSahajournals.orgVisit source






