Key Takeaways
- In 2021, approximately 1.17 million people aged 12 or older in the United States had heroin use disorder in the past year according to the National Survey on Drug Use and Health
- Globally, heroin addiction affects an estimated 10.6 million people who inject drugs as of 2019 data from the United Nations Office on Drugs and Crime
- In the US, past-year heroin use among adults aged 18-25 increased by 220% from 2002 to 2012 per CDC data
- Men aged 18-25 in the US have a 1.2% lifetime risk of heroin use disorder per NIDA
- White non-Hispanics comprised 70% of heroin overdose deaths in 2020 despite being 60% of population per CDC
- African Americans had heroin use disorder rates of 0.3% vs 0.5% for Whites in 2021 NSDUH
- Heroin causes respiratory depression leading to 70% of overdose deaths per CDC autopsy data 2020
- Chronic heroin use leads to liver disease in 40% of injectors due to hepatitis C per NIH 2022
- Heroin addicts have 15x higher HIV risk from needle sharing per CDC 2021 estimates
- Heroin buprenorphine treatment reduces overdose risk by 50% per 2021 RCT
- Methadone maintenance achieves 60% retention at 1 year for heroin addiction per Cochrane review 2019
- Naltrexone implants show 70% abstinence at 6 months vs 40% oral per Australian trials 2020
- Heroin addiction treatment costs US $35 billion annually in healthcare per CDC 2022 estimates
- Lost productivity from heroin addiction totals $20 billion yearly in US workforce per HHS 2021
- Heroin-related crime costs US cities $5 billion in policing and courts per 2019 Urban Institute
Heroin addiction affects millions globally and is a devastating public health crisis.
Demographics
- Men aged 18-25 in the US have a 1.2% lifetime risk of heroin use disorder per NIDA
- White non-Hispanics comprised 70% of heroin overdose deaths in 2020 despite being 60% of population per CDC
- African Americans had heroin use disorder rates of 0.3% vs 0.5% for Whites in 2021 NSDUH
- Ages 26-34 group had highest heroin use at 0.9% past year in US 2021 data
- Males account for 70% of heroin-related hospital admissions in the US per HCUP 2019
- Rural residents had 50% higher opioid use disorder including heroin rates than urban in 2018-19 per JAMA
- Among US Hispanics, heroin use was 0.3% past year in 2021, higher in males at 0.5%
- Low-income households (<$20k) had 3x heroin use disorder prevalence vs high-income per NSDUH 2020
- Veterans represent 10% of US heroin addiction cases despite 7% of population per VA 2022 report
- Women with heroin addiction average first use at 22.5 years vs 23.8 for men per NIDA studies
- Native Americans have 2.5x higher heroin overdose rates than Whites per CDC 2021
- Unemployed US adults had 1.1% heroin use disorder rate vs 0.3% employed in 2021
- In Appalachia states, 40% of heroin users are under 30 per 2017 regional surveys
- LGBTQ+ youth have 4x higher odds of heroin use than heterosexual peers per 2021 Youth Risk Behavior Survey
- College non-graduates have 2x heroin addiction rates of graduates per NSDUH 2019 analysis
- Single/never married adults show 60% of heroin use disorders vs 40% married per 2021 data
- In urban US centers, Black males aged 25-34 have rising heroin use from 0.2% to 0.6% 2015-2021
- Pregnant women in low SES areas have 5x heroin exposure risk per 2020 maternal health studies
- Foster care alumni have 3x lifetime heroin use rates at 15% per child welfare studies 2018
- Mental health comorbidity present in 55% of female heroin addicts vs 40% males per SAMHSA 2021
- Ages 35-49 now represent 35% of new heroin treatment admissions up from 20% in 2010 per TEDS
- Asian Americans lowest at 0.1% heroin use disorder but rising 50% since 2015 per NSDUH
- Criminal justice involved individuals have 10x heroin addiction rates at 20% per BJS 2019
- Heroin users with high school diploma or less comprise 75% of cases per 2021 NSDUH
- Midwestern US states show highest female heroin use at 0.4% past year 2021
- Heroin injection common in 65% of users aged 25+ per 2019 PATH study
- Chronic pain patients transitioning to heroin are 80% white males over 40 per 2020 studies
- Heroin addiction peaks in winter months with 20% higher admissions for ages 18-24 per regional data
- 45% of US heroin addicts have family history of substance use per NIDA genetics studies
Demographics Interpretation
Health Impacts
- Heroin causes respiratory depression leading to 70% of overdose deaths per CDC autopsy data 2020
- Chronic heroin use leads to liver disease in 40% of injectors due to hepatitis C per NIH 2022
- Heroin addicts have 15x higher HIV risk from needle sharing per CDC 2021 estimates
- Endocarditis from heroin injection affects 30% of long-term users per IDSA guidelines 2019
- Heroin withdrawal symptoms peak at 48-72 hours with 90% experiencing severe nausea per NIDA
- Brain imaging shows 25% dopamine transporter loss in chronic heroin users per NIH PET studies
- Heroin users have 50% higher pneumonia rates due to suppressed immunity per 2020 Lancet study
- Neonatal abstinence syndrome from maternal heroin use affects 80% of exposed infants per CDC
- Heroin collapses veins in 70% of injectors after 5 years per vascular studies 2018
- Cognitive impairment persists in 60% of abstinent heroin users after 1 year per meta-analysis 2021
- Heroin overdose hypoxia causes permanent brain damage in 20% of survivors per NEJM 2019
- 35% of heroin users develop skin abscesses from injection per emergency dept data 2020
- Heroin linked to 10% higher tuberculosis rates in addicts per WHO 2022
- Erectile dysfunction in 50% of male heroin users under 40 per urology studies 2017
- Heroin use doubles stroke risk under age 50 per AHA 2021 data
- Amenorrhea in 40% of female heroin addicts due to hypothalamic suppression per endo studies
- Heroin addicts have 3x sepsis hospitalization rates per 2019 HCUP analysis
- Renal failure from heroin adulterants affects 15% of users per nephrology reports 2020
- Heroin induces tolerance requiring 4x dose increase in 6 months for 80% users per pharm studies
- Osteoporosis risk 2.5x higher in long-term heroin users per bone density scans 2018
- Heroin sniffing causes nasal septum perforation in 25% chronic users per ENT data
- Depression comorbidity in 50% heroin addicts with 2x suicide attempt rate per 2021 meta-analysis
- Heroin users average 10 years lower life expectancy at 55 years per actuarial studies 2020
- Pancreatitis acute cases 5x higher in heroin ER visits per 2019 data
- Heroin accelerates gum disease with 70% tooth loss by age 40 per dental studies
- Peripheral neuropathy in 30% of heroin smokers per neuro exams 2022
- Heroin withdrawal increases heart attack risk 3x in first week per cardio data 2017
- Methicillin-resistant staph infections in 40% of heroin abscess cases per ID week 2020
Health Impacts Interpretation
Prevalence
- In 2021, approximately 1.17 million people aged 12 or older in the United States had heroin use disorder in the past year according to the National Survey on Drug Use and Health
- Globally, heroin addiction affects an estimated 10.6 million people who inject drugs as of 2019 data from the United Nations Office on Drugs and Crime
- In the US, past-year heroin use among adults aged 18-25 increased by 220% from 2002 to 2012 per CDC data
- About 828,000 Americans reported using heroin in the past year in 2019 NSDUH survey results
- Heroin initiation rates peaked at 169,000 new users in 2015 among those aged 12+, dropping to 78,000 by 2020 per SAMHSA
- In Europe, 1.3 million high-risk opioid users including heroin were reported in 2022 by the European Monitoring Centre for Drugs and Drug Addiction
- US past-month heroin use was 0.3% among adults 26+ in 2021, equating to roughly 670,000 people
- From 2010-2020, heroin-involved overdose deaths rose from 3,039 to 13,185 annually in the US per CDC WONDER database
- Approximately 23% of individuals who use heroin develop opioid use disorder according to NIDA research summaries
- In 2019, 0.2% of US adolescents aged 12-17 reported past-year heroin use per NSDUH
- Heroin use disorder prevalence among US adults was 0.4% in 2021, highest in ages 26-34 at 0.7%
- Worldwide, opioid use disorder including heroin impacted 40-50 million people in 2019 per Global Burden of Disease study
- In Appalachia, heroin use rates were 3 times national average in 2017 CDC surveys
- Past-year heroin use among US males was 0.5% vs 0.2% for females in 2021 NSDUH
- Heroin accounted for 15% of all illicit drug use initiations among US youth in 2015 per Monitoring the Future
- In Canada, 0.8% of population aged 15+ reported past-year opioid use including heroin in 2018 per Canadian Alcohol and Drugs Survey
- US heroin use disorder remission rates are low with only 40% achieving 1-year abstinence per NIDA longitudinal studies
- In 2022, Scotland reported 1,300 problem drug users per 100,000 for opioids mainly heroin per Public Health Scotland
- Heroin use in US declined 12% from 2019 to 2021 but remained at 370,000 past-year users aged 12+
- In Australia, 0.1% of adults used heroin in past year as of 2019 National Drug Strategy Household Survey
- Heroin use disorder affects 1 in 200 US adults aged 18+ based on 2021 prevalence estimates
- In Mexico, heroin use prevalence was 0.4% among adults in 2016-17 ENCODAT survey
- US military veterans have 2x higher heroin use disorder rates at 1.5% per VA studies 2020
- Past-year heroin use in US urban areas was 0.4% vs 0.2% rural in 2019 NSDUH
- Globally, 80% of heroin consumption occurs in Asia per UNODC World Drug Report 2023
- In 2020, 4.3 million US adults reported lifetime heroin use per NSDUH
- Heroin use among US pregnant women was 0.1% in 2021, linked to 20,000 neonatal cases
- In the UK, 281,000 adults used opiates including heroin in past year 2019-2020 Crime Survey
- US heroin overdose deaths per 100,000 population rose from 1.0 in 2010 to 4.4 in 2020 per CDC
- 13.5% of US adults with pain medication misuse progressed to heroin use per 2015 NSDUH analysis
Prevalence Interpretation
Social Economic
- Heroin addiction treatment costs US $35 billion annually in healthcare per CDC 2022 estimates
- Lost productivity from heroin addiction totals $20 billion yearly in US workforce per HHS 2021
- Heroin-related crime costs US cities $5 billion in policing and courts per 2019 Urban Institute
- Foster care placements due to parental heroin addiction rose 30% to 40% of cases 2010-2020 per HHS
- Heroin epidemic reduced US male labor participation by 1% or 800,000 workers per NBER 2019
- Emergency department visits for heroin cost $10 billion annually in US per 2020 HCUP
- Child welfare spending on heroin-affected families hit $15 billion in 2021 per NASW reports
- Heroin addiction correlates with 50% family income drop averaging $30k loss per household per 2018 studies
- Incarceration for heroin offenses costs $80 billion yearly nationwide per BJS 2022
- Homelessness among heroin addicts is 25% of total US homeless population per HUD 2021
- Heroin trafficking generates $50 billion black market revenue in US per DEA 2023 estimates
- Workplace absenteeism from heroin use costs employers $2 billion monthly per SHRM 2020
- Heroin orphans number 300,000 in US with $10 billion welfare costs per Annie E Casey 2019
- Property crime linked to heroin funding up 20% in opioid hotspots per FBI UCR 2021
- Medicaid spending on heroin treatment and complications reached $25 billion in 2020 per CMS
- Divorce rates 2x higher in heroin-addicted households at 60% per 2017 family studies
- Heroin crisis cut US GDP by 0.5% or $120 billion in 2017 per economic modeling
- School dropout among teen heroin users 40% vs 5% non-users per 2021 YRBS analysis
- Heroin-related suicides cost society $1 billion in lost earnings per CDC 2020 WISQARS
- Community treatment programs save $7 per $1 spent on heroin addiction per WSIPP 2019
- Heroin use increases domestic violence reports 3x per NCADV 2021 data
- Insurance premiums rose 15% due to heroin claims in employer plans per 2020 Milliman
- Rural hospitals closed 10% due to uncompensated heroin care per GAO 2022
- Heroin addiction stigma reduces employment 30% post-recovery per 2018 labor studies
- Global heroin trade funds terrorism with $400 million to groups per UNODC 2023
Social Economic Interpretation
Treatment
- Heroin buprenorphine treatment reduces overdose risk by 50% per 2021 RCT
- Methadone maintenance achieves 60% retention at 1 year for heroin addiction per Cochrane review 2019
- Naltrexone implants show 70% abstinence at 6 months vs 40% oral per Australian trials 2020
- Contingency management boosts heroin abstinence 2x with voucher incentives per NIDA trials
- Buprenorphine-naloxone combo reduces illicit opioid use by 75% in first month per 2022 meta-analysis
- Cognitive behavioral therapy adds 20% to abstinence rates over detox alone per SAMHSA 2021
- 12-step programs like NA achieve 25% 5-year sobriety for heroin addicts per long-term studies 2018
- Telehealth opioid treatment reaches 40% more rural heroin addicts per 2020 VA evaluation
- Detox success without MAT is only 10% at 90 days for heroin dependence per ASAM data
- Vivitrol monthly injections maintain 50% opioid-negative urine tests at 6 months per FDA trials
- Integrated mental health treatment improves heroin recovery by 35% per 2019 RCT
- Heroin anonymous meetings attendance correlates with 40% relapse reduction per 2021 survey
- Rapid detox under anesthesia has 80% dropout by 3 months vs standard 50% per critiques 2017
- MAT with counseling retains 55% at 12 months vs 20% counseling alone per TEDS 2020
- Family therapy in adolescent heroin treatment doubles completion rates to 60% per 2018 studies
- Lofexidine FDA-approved reduces withdrawal severity by 40% vs placebo per phase 3 trials 2018
- Peer recovery coaching improves 6-month abstinence by 25% in heroin programs per 2022 RCT
- Extended-release morphine for withdrawal eases symptoms 50% more than clonidine per 2019 trial
- Housing first models retain 70% heroin clients in treatment vs 30% standard care per HUD studies
- Acupuncture adjunct therapy cuts cravings 30% in heroin detox per meta-analysis 2020
- SAMHSA-funded programs treat 1.5 million opioid episodes yearly including 30% heroin per 2021
- Genetic testing for CYP2D6 improves naltrexone response by 40% in heroin patients per 2022
- Mindfulness-based relapse prevention sustains 45% sobriety at 15 months vs 25% standard per RCT
- Emergency MAT initiation post-overdose reduces re-admission 40% per 2021 NEJM study
- Vocational rehab in treatment programs boosts employment 50% for recovered heroin users per 2020
Treatment Interpretation
Sources & References
- Reference 1SAMHSAsamhsa.govVisit source
- Reference 2UNODCunodc.orgVisit source
- Reference 3CDCcdc.govVisit source
- Reference 4NIDAnida.nih.govVisit source
- Reference 5EMCDDAemcdda.europa.euVisit source
- Reference 6WONDERwonder.cdc.govVisit source
- Reference 7HEALTHDATAhealthdata.orgVisit source
- Reference 8MONITORINGTHEFUTUREmonitoringthefuture.orgVisit source
- Reference 9CANADAcanada.caVisit source
- Reference 10PUBLICHEALTHSCOTLANDpublichealthscotland.scotVisit source
- Reference 11AIHWaihw.gov.auVisit source
- Reference 12GOBgob.mxVisit source
- Reference 13PUBLICHEALTHpublichealth.va.govVisit source
- Reference 14GOVgov.ukVisit source
- Reference 15HCUP-UShcup-us.ahrq.govVisit source
- Reference 16JAMANETWORKjamanetwork.comVisit source
- Reference 17VAva.govVisit source
- Reference 18NIHnih.govVisit source
- Reference 19ACFacf.hhs.govVisit source
- Reference 20BJSbjs.ojp.govVisit source
- Reference 21NCBIncbi.nlm.nih.govVisit source
- Reference 22NIAIDniaid.nih.govVisit source
- Reference 23IDSOCIETYidsociety.orgVisit source
- Reference 24NIMHnimh.nih.govVisit source
- Reference 25THELANCETthelancet.comVisit source
- Reference 26NEJMnejm.orgVisit source
- Reference 27ACEPacep.orgVisit source
- Reference 28WHOwho.intVisit source
- Reference 29AHAJOURNALSahajournals.orgVisit source
- Reference 30KIDNEYkidney.orgVisit source
- Reference 31ACADEMICacademic.oup.comVisit source
- Reference 32COCHRANELIBRARYcochranelibrary.comVisit source
- Reference 33HSRDhsrd.research.va.govVisit source
- Reference 34ASAMasam.orgVisit source
- Reference 35FDAfda.govVisit source
- Reference 36HUDUSERhuduser.govVisit source
- Reference 37ASPEaspe.hhs.govVisit source
- Reference 38URBANurban.orgVisit source
- Reference 39NBERnber.orgVisit source
- Reference 40SOCIALWORKERSsocialworkers.orgVisit source
- Reference 41DEAdea.govVisit source
- Reference 42SHRMshrm.orgVisit source
- Reference 43AECFaecf.orgVisit source
- Reference 44UCRucr.fbi.govVisit source
- Reference 45MEDICAIDmedicaid.govVisit source
- Reference 46BROOKINGSbrookings.eduVisit source
- Reference 47WSIPPwsipp.wa.govVisit source
- Reference 48NCADVncadv.orgVisit source
- Reference 49MILLIMANmilliman.comVisit source
- Reference 50GAOgao.govVisit source






