Key Takeaways
- As of December 31, 2022, there were 3,413 active adult candidates on the U.S. heart transplant waiting list, representing a 2.1% decrease from 2021.
- In 2022, 3,526 new adult patients were added to the heart waiting list in the U.S., a 4.7% increase from the previous year.
- The total number of heart transplant registrations in the U.S. reached 4,127 in 2021, including inactive listings.
- Males comprised 70.4% of the 3,413 active adult heart waiting list candidates as of December 31, 2022.
- Age group 18-49: 18.2% (622 patients) on heart waitlist end-2022.
- White patients: 59.3% (2,024) of adult heart waitlist in 2022.
- 89.6% of pediatric heart candidates had congenital heart disease.
- Dilated cardiomyopathy: 41.8% (1,428) primary diagnosis adult heart list 2022.
- Status 4 (stable): 28.3% (965) of active heart list end-2022.
- 31.7% of heart transplant waitlist mortality occurred within 3 months of listing in 2022.
- Median wait time for Status 1A heart: 12 days in 2022 U.S. data.
- Pre-transplant mortality rate: 298 per 100 waitlist years for adults 2022.
- Region 7 had 3,289 active heart candidates at end of 2022, highest regionally.
- California programs listed 612 heart candidates end-2022 (18%).
- OPO Region 3: 456 new heart adds in 2022.
Heart transplant waiting list trends show fewer adults but more pediatric patients needing hearts.
Clinical Status and Diagnoses
Clinical Status and Diagnoses Interpretation
Geographic and Program-Specific Data
Geographic and Program-Specific Data Interpretation
Patient Demographics
Patient Demographics Interpretation
Total Waiting List Size and Additions
Total Waiting List Size and Additions Interpretation
Wait Times and Outcomes
Wait Times and Outcomes Interpretation
Sources & References
- Reference 1OPTNoptn.transplant.hrsa.govVisit source
- Reference 2SRTRsrtr.transplant.hrsa.govVisit source
- Reference 3UNOSunos.orgVisit source
- Reference 4PUBMEDpubmed.ncbi.nlm.nih.govVisit source
- Reference 5JAMANETWORKjamanetwork.comVisit source
- Reference 6NCBIncbi.nlm.nih.govVisit source
- Reference 7JHEARTLUNGTRANSPLANTjheartlungtransplant.orgVisit source
- Reference 8ATSJOURNALSatsjournals.orgVisit source
- Reference 9JHLTONLINEjhltonline.orgVisit source






