Key Takeaways
- In England and Wales, drug poisoning deaths reached 5,583 in 2021 registrations, the highest on record
- UK drug-related deaths totaled 7,838 in 2022 across all nations, up 35% from 2019
- Scotland recorded 1,330 drug-related deaths in 2022, a rate of 23.4 per 100,000 population
- Heroin/morphine involved in 3,937 deaths in E&W 2021 (71%)
- Fentanyl detected in 180 UK deaths in 2022, up from 60 in 2020
- Methadone caused 724 deaths in E&W 2021, 13% of total opioid deaths
- Cocaine involved in 1,006 deaths in E&W 2021, 18% of total
- Crack cocaine deaths 693 in E&W 2021, up 33% from 2020
- Amphetamines caused 217 deaths in E&W 2021
- 75% of drug deaths male in E&W 2021 (4,228 males vs 1,355 females)
- Peak age for drug deaths 45-49 in E&W 2021 with 1,167 deaths
- Females drug death rate rose 15% to 10.4 per 100k in Scotland 2022
- London females drug death rate 8.2 per 100k vs males 14.5 in 2021
- Scotland Inverclyde highest drug death rate 2022 at 52.2 per 100k
- Blackpool E&W highest rate 2021 at 35.4 per 100k population
Record drug deaths in the UK, largely involving opioids, continue to tragically rise each year.
Demographic Breakdowns
- 75% of drug deaths male in E&W 2021 (4,228 males vs 1,355 females)
- Peak age for drug deaths 45-49 in E&W 2021 with 1,167 deaths
- Females drug death rate rose 15% to 10.4 per 100k in Scotland 2022
- 20-29 year olds 12% of E&W drug deaths but rate 18.6 per 100k males
- NI males 85% of drug deaths 2021 (156 of 184)
- Deprived areas 5x higher drug death rate in Scotland 2022 (SIMD1 50.9 vs SIMD5 5.2 per 100k)
- White ethnic group 95% of E&W drug deaths 2021 (5,301)
- Over 50s drug deaths doubled since 2012 to 1,800 in E&W 2021
- Females 40-44 peak rate 19.2 per 100k in Scotland 2022
- Unmarried 88% of known marital status drug deaths E&W 2021
- 35-39 males 1,022 drug deaths E&W 2021, highest subgroup
- Asian ethnic 1.5% of E&W drug deaths 2021 (84)
- Scotland 50-59 males rate 45.2 per 100k 2022
- Females under 20 rare 4 deaths E&W 2021
- NI 25-34 age 40% of deaths 2021 (74)
- Mixed ethnic 1% E&W drug deaths (56) 2021
- Scotland SIMD quintile 1 45% of all deaths 2022 despite 20% pop
- Over 65s 2% drug deaths E&W 2021 (112)
- Black ethnic 0.8% E&W (45 deaths) 2021
- Males 30-34 peak NI rate 20.1 per 100k 2021
Demographic Breakdowns Interpretation
Opioid-Related Deaths
- Heroin/morphine involved in 3,937 deaths in E&W 2021 (71%)
- Fentanyl detected in 180 UK deaths in 2022, up from 60 in 2020
- Methadone caused 724 deaths in E&W 2021, 13% of total opioid deaths
- Scotland opioid deaths 1,051 in 2022, 79% of total drug deaths
- Tramadol involved in 458 E&W deaths 2021, often with other drugs
- Buprenorphine deaths 142 in E&W 2021, stable from prior years
- Codeine deaths 281 in E&W 2021, mostly with antidepressants
- Dihydrocodeine 187 deaths in E&W 2021
- Oxycodone 472 deaths in E&W 2021, rising trend
- Morphine/heroin poly-drug deaths 85% of opioid cases in Scotland 2022
- NI opioid deaths 132 in 2021, 72% of total
- Fentanyl analogue deaths tripled in UK 2017-2022 to 200+
- Heroin deaths 2,469 in UK 2020
- Methadone poly-use in 60% of 700+ Scottish opioid deaths 2021
- Synthetic opioids excluding methadone up 50% in E&W 2020-2021
- Heroin/morphine primary in 50% of E&W deaths 2021 but poly 90%
- Fentanyl deaths UK 2021: 127 confirmed
- Pethidine rare opioid 5 deaths E&W 2021
- Diamorphine (heroin) toxicology positive in 2,800 E&W deaths 2021
- Scotland 2022 benzodiazepine with opioid in 80% of 1,051 opioid deaths
- Tapentadol emerging opioid 22 deaths E&W 2021
- NI heroin/morphine 112 of 132 opioid deaths 2021
- Etorphine veterinary opioid 2 UK deaths 2020-2022
- Hydromorphone 15 deaths E&W 2021
- Scotland methadone deaths 229 in 2022
Opioid-Related Deaths Interpretation
Overall Statistics
- In England and Wales, drug poisoning deaths reached 5,583 in 2021 registrations, the highest on record
- UK drug-related deaths totaled 7,838 in 2022 across all nations, up 35% from 2019
- Scotland recorded 1,330 drug-related deaths in 2022, a rate of 23.4 per 100,000 population
- England saw 4,907 drug poisoning deaths in 2021, 75% involving opioids
- Northern Ireland had 184 drug misuse deaths in 2021, rate of 9.9 per 100,000
- Total UK drug deaths increased by 12% from 2020 to 2021 to over 7,000
- Drug poisoning accounted for 1 in 35 deaths among 20-39 year olds in England/Wales 2021
- 80% of drug deaths in UK 2022 involved illicit/natural drugs
- Overdose deaths in UK rose 20% in 2020 due to COVID, to 5,661 in E&W
- Scotland's drug death rate 3x EU average at 24.3 per 100k in 2021
- In 2020, England and Wales recorded 4,825 drug-related deaths, a 49% increase since 2012
- Scotland's 2021 drug deaths hit 1,187, rate of 21.0 per 100,000, highest ever
- Total UK synthetic opioid mentions in deaths rose to 258 in 2021
- Drug misuse deaths in England 2022 provisional 3,900+
- 2,500 hospital admissions daily for drug harms UK pre-2020, linked to deaths
Overall Statistics Interpretation
Regional Variations
- London females drug death rate 8.2 per 100k vs males 14.5 in 2021
- Scotland Inverclyde highest drug death rate 2022 at 52.2 per 100k
- Blackpool E&W highest rate 2021 at 35.4 per 100k population
- NI Belfast 25% of all drug deaths 2021 (46 of 184)
- North East England drug death rate 22.3 per 100k 2021, highest region
- Dundee City Scotland 43.6 per 100k drug deaths 2022
- Wales drug deaths 323 in 2021, rate 10.3 per 100k
- East of England lowest regional rate 9.2 per 100k E&W 2021
- Glasgow City 1,330 total but rate 38.9 per 100k Scotland 2022
- Middlesbrough 30.8 per 100k, top local authority E&W 2021
- Manchester rate 23.6 per 100k 2021 E&W
- West Dunbartonshire Scotland 47.2 per 100k 2022
- Liverpool 27.4 per 100k drug deaths 2021
- North Wales 12.1 per 100k vs South 9.8 2021
- Edinburgh Scotland 25.3 per 100k 2022
- South East England 8.5 per 100k lowest 2021
- Renfrewshire 41.8 per 100k Scotland 2022
- County Durham 25.2 per 100k E&W 2021
- West Midlands 14.6 per 100k 2021
- East Renfrewshire lowest Scotland 4.3 per 100k 2022
Regional Variations Interpretation
Stimulant-Related Deaths
- Cocaine involved in 1,006 deaths in E&W 2021, 18% of total
- Crack cocaine deaths 693 in E&W 2021, up 33% from 2020
- Amphetamines caused 217 deaths in E&W 2021
- MDMA/ecstasy 92 deaths in E&W 2021
- Scotland cocaine deaths 216 in 2022, 16% increase
- Benzoylecgonine (cocaine metabolite) in 20% of NI drug deaths 2021
- Novel psychoactive stimulants like cathinones in 50 UK deaths 2022
- Cocaine deaths quadrupled in UK since 2012 to 1,200+ in 2021
- Methamphetamine rare but 30 deaths in E&W 2021
- Crack cocaine with opioids in 40% of stimulant deaths Scotland 2022
- Ecstasy deaths mostly under 30s, 70 cases UK 2020
- UK cocaine purity linked to 25% rise in deaths 2019-2022
- Males 45-49 highest cocaine death rate 2021 E&W at 15.2 per 100k
- Cocaine hydrochloride 418 deaths E&W 2021 excluding crack
- Scotland amphetamines/meth 48 deaths 2022
- MDEA ecstasy variant 3 deaths E&W 2021
- Caffeine stimulant co-factor in 100+ deaths but not primary
- NI cocaine 45 deaths 2021, 24% of total
- PMMA super-strength ecstasy 5 UK deaths 2010s peak
- 4-MMC mephedrone residual 10 deaths E&W 2021
- Scotland crack cocaine 112 deaths 2022, up 25%
- MDA ecstasy 12 deaths E&W 2021
- Khat stimulant negligible 2 mentions UK deaths 2021
Stimulant-Related Deaths Interpretation
Trends Over Time
- Drug deaths in E&W rose from 2,927 in 2012 to 5,583 in 2021, 90% increase
- Scotland drug deaths peaked at 1,330 in 2022, up from 976 in 2018
- UK opioid deaths tripled 1993-2021 from 1,000 to 4,500+
- Cocaine deaths E&W from 112 in 2012 to 1,006 in 2021, 8x rise
- NI drug deaths steady 150-200 annually 2015-2021
- Post-COVID spike: E&W deaths +20% 2020-2021
- Heroin deaths halved in UK 2012-2021 but methadone stable
- Female rates Scotland up 100% 2015-2022 to 17.6 per 100k
- NPS deaths fell from 100+ in 2015 to under 20 in 2021 UK
- 45-54 age group deaths doubled 2001-2021 in E&W
- E&W drug deaths stable 2019 then +13% 2021
- Scotland consecutive record highs 2018-2022, 976 to 1,330
- UK crack deaths up 300% 2011-2021
- Opioid deaths E&W flat 4,000-5,000 2015-2021
- NI peak 227 in 2018 then down to 184 2021
- Poly-drug use in 90% deaths up from 80% in 2000s E&W
- Benzodiazepines in deaths doubled Scotland 2015-2022
- Youth deaths down 50% since 2000s in E&W
- Fentanyl emergence post-2016 +200% mentions UK
- Middle-age deaths now 50%+ of total vs youth in 1990s
Trends Over Time Interpretation
Sources & References
- Reference 1ONSons.gov.ukVisit source
- Reference 2GOVgov.ukVisit source
- Reference 3PUBLICHEALTHSCOTLANDpublichealthscotland.scotVisit source
- Reference 4NISRAnisra.gov.ukVisit source
- Reference 5PRIpri.orgVisit source
- Reference 6EMCDDAemcdda.europa.euVisit source
- Reference 7FINGERTIPSfingertips.phe.org.ukVisit source
- Reference 8KINGSFUNDkingsfund.org.ukVisit source






