Key Takeaways
- In 2021, there were 21,693 donor egg or donor embryo cycles reported to the CDC in the United States, accounting for 12.7% of all assisted reproductive technology (ART) cycles.
- Between 2015 and 2021, donor oocyte cycles in the US increased by 28%, from 16,945 to 21,693 cycles annually.
- In 2020, US clinics performed 20,076 fresh donor egg cycles with a live birth rate of 52.3% per intended retrieval.
- For women under 35 using donor eggs, live birth rate per transfer is 60.3% (SART 2022).
- Overall donor egg IVF live birth rate: 51.4% per cycle in US 2021 CDC data.
- Frozen donor egg transfers: 56.5% live birth rate vs 47.2% fresh (SART 2022).
- Average donor age in US: 26.5 years (SART 2022).
- 92% of US egg donors are Caucasian (CDC 2021).
- Mean BMI of egg donors: 22.8 kg/m² (SART data).
- Recipients aged 40-44: 45% of donor egg users (US 2021).
- 30% of donor egg recipients over 45 years old (SART 2022).
- Premature ovarian failure accounts for 25% recipient diagnoses.
- Average donor egg IVF cost: $25,000-$35,000 per cycle in US 2023.
- Donor compensation average: $8,000 per cycle (FDA max $10K).
- Frozen donor egg vial: $15,000-$20,000 + meds/storage.
Donor egg IVF is growing rapidly with high success rates over 50%.
Costs and Risks
- Average donor egg IVF cost: $25,000-$35,000 per cycle in US 2023.
- Donor compensation average: $8,000 per cycle (FDA max $10K).
- Frozen donor egg vial: $15,000-$20,000 + meds/storage.
- Insurance coverage for donor IVF: <10% US plans.
- UK donor egg cycle: £8,000-£12,000 private.
- Multiple pregnancies add $50K+ neonatal costs.
- Egg freezing for donation banks: $5,000-$10,000 upfront.
- Annual storage fee: $500-$1,000 per donor batch.
- Spain donor egg package: €5,000-€7,000 all-inclusive.
- Legal fees for donor contracts: $1,000-$3,000.
- OHSS risk in donors: 1-5%, severe 0.5%.
- Miscarriage risk donors post-cycle: 2% elevated.
- Recipient preeclampsia risk: 15% (vs 8% natural).
- Preterm birth rate: 25% in donor egg pregnancies.
- Hypertension risk: 20% higher in recipients >45.
- Placental issues: 12% incidence donor IVF.
- Low birth weight: 20% of donor egg babies.
- Congenital anomalies: no increased risk vs natural (meta-analysis).
- Donor psychological risks: 5% regret rate.
- Recipient thrombosis risk: 1-2%.
- Long-term child health: equivalent to natural.
- Cumulative cost for success: $40,000 avg (2 cycles).
- Global insurance avg coverage: 20% donor IVF.
- Severe OHSS hospitalization: 0.2% donors.
- Postpartum hemorrhage: 10% higher risk.
Costs and Risks Interpretation
Donor Characteristics
- Average donor age in US: 26.5 years (SART 2022).
- 92% of US egg donors are Caucasian (CDC 2021).
- Mean BMI of egg donors: 22.8 kg/m² (SART data).
- 75% of donors have college education or higher.
- 85% anonymous donors vs 15% known/identity-release.
- Average eggs retrieved per donor: 18-22 (2022 clinic avg).
- 65% of donors under 28 years old (FDA screened).
- Ethnic breakdown: 5% Asian, 3% Black, 92% White donors US.
- 40% of donors have siblings with fertility history screened.
- Genetic testing: 98% donors tested for 200+ conditions.
- Average donor height: 5'6" (168 cm) in US programs.
- 70% donors non-smokers, 95% no drug history.
- Psychological eval pass rate for donors: 95%.
- 25% donors athletic/bodybuilder physique.
- Mean donor family income: $75,000+ annually.
- 60% donors with artistic talents (music/art).
- Infectious disease screen negative: 99.9% donors.
- 15% donors of Hispanic/Latino origin (2022).
- Average donor weight: 125 lbs (57 kg).
- 80% donors from urban areas.
- Karyotype normal: 99.5% of screened donors.
- 50% donors with graduate degrees.
- Hair color: 55% brown, 30% blonde, 10% black.
- 90% donors nulliparous (no prior births).
- Eye color: 45% brown, 40% blue, 15% other.
- 35% donors with STEM backgrounds.
Donor Characteristics Interpretation
Recipient Profiles
- Recipients aged 40-44: 45% of donor egg users (US 2021).
- 30% of donor egg recipients over 45 years old (SART 2022).
- Premature ovarian failure accounts for 25% recipient diagnoses.
- 55% recipients married/partnered, 20% single.
- Average recipient age: 43.2 years (2021 CDC).
- 15% recipients with endometriosis history.
- 40% recipients from top 10 US metro areas.
- BMI >30 in 22% donor egg recipients.
- 28% recipients same-sex couples (2022).
- 65% recipients Caucasian, similar to donors.
- Prior failed IVF with own eggs: 60% recipients.
- 10% recipients with Turner syndrome.
- Average parity before donor IVF: 0.8 children.
- 35% recipients from Northeast US.
- Education: 70% college grads among recipients.
- 18% recipients with uterine factor infertility.
- International patients: 12% of US donor egg cycles.
- 50% recipients on 2nd+ donor cycle.
- Mean recipient income: $150K+ household.
- 25% recipients with genetic concerns.
- Smokers: 5% of donor egg recipients.
- 20% recipients Asian ethnicity.
- Hysterectomy prior: 8% recipients.
- 42% recipients 44+ years (UK data).
Recipient Profiles Interpretation
Success Rates
- For women under 35 using donor eggs, live birth rate per transfer is 60.3% (SART 2022).
- Overall donor egg IVF live birth rate: 51.4% per cycle in US 2021 CDC data.
- Frozen donor egg transfers: 56.5% live birth rate vs 47.2% fresh (SART 2022).
- Donor egg success for recipients 40-42: 52.1% live births per transfer (2021).
- UK HFEA 2021: 42% live birth rate per donor egg embryo transfer.
- PGT-A in donor egg cycles boosts success to 65% per transfer (2022 study).
- Spain donor egg clinics report 55-70% success per transfer.
- Multiple pregnancy rate in donor egg IVF: 18% twins, 1% triplets (US 2021).
- Cumulative live birth rate after 2 donor egg transfers: 70% (SART).
- Donor egg IVF success >50% even for recipients over 50 (2022 data).
- ESHRE 2018: 49.3% delivery rate per donor oocyte transfer.
- US 2021: 11,344 live births from donor eggs, avg 0.52 per cycle.
- Singleton birth rate 82% in elective single embryo transfer donor cycles.
- Miscarriage rate in donor egg IVF: 13.5% (vs 25% own eggs over 40).
- Implantation rate per donor egg embryo: 48% (2022 SART).
- Australia 2021: 48.6% live birth rate per donor egg transfer.
- Ongoing pregnancy rate 55% per frozen donor egg transfer (clinic data).
- Success drops to 45% if recipient BMI >30 in donor egg IVF.
- 62% live birth rate for recipients <35 with donor eggs (SART 2022).
- Donor egg cycles with blastocyst transfer: 58% success vs 45% day 3.
- Canada CARTR 2020: 50.2% live birth per donor oocyte transfer.
- OHSS incidence <1% in donor egg recipients (2021 data).
- 70% of donor egg IVF patients achieve pregnancy within 2 cycles.
- Live birth rate per donor egg: 25-30% (due to multiple eggs).
- 2022: 59% success for frozen euploid donor embryos.
- Donors aged 21-25 yield 5% higher success than 26-30 (study).
- 90% of donor egg IVF births are full-term.
Success Rates Interpretation
Usage Statistics
- In 2021, there were 21,693 donor egg or donor embryo cycles reported to the CDC in the United States, accounting for 12.7% of all assisted reproductive technology (ART) cycles.
- Between 2015 and 2021, donor oocyte cycles in the US increased by 28%, from 16,945 to 21,693 cycles annually.
- In 2020, US clinics performed 20,076 fresh donor egg cycles with a live birth rate of 52.3% per intended retrieval.
- Donor egg IVF accounted for 15% of all IVF cycles in US clinics reporting to SART in 2022.
- From 2017 to 2022, the proportion of frozen donor egg transfers rose from 35% to 58% of all donor egg transfers in the US.
- In Europe, ESHRE reported 45,659 donor oocyte cycles in 2018, up 12% from 2016.
- UK HFEA data shows 3,427 donor egg cycles in 2021, representing 18% of all IVF cycles.
- Australia’s 2021 ANZARD registry recorded 2,456 donor egg treatments, a 15% increase from 2017.
- In 2019, Spain performed over 100,000 donor egg cycles, leading Europe with 25% market share.
- Canada reported 1,892 donor egg cycles in 2020 per CARTR data, 10% of total ART.
- Brazil’s 2022 registry showed 8,500 donor egg IVF cycles, doubling since 2015.
- In 2021, 65% of donor egg cycles in the US used frozen eggs, up from 22% in 2015.
- Global donor egg market projected to grow from $2.5B in 2023 to $4.1B by 2030 at 7.2% CAGR.
- US donor egg cycles per million population: 65 in 2021.
- 2022 SART data: 25,400 donor oocyte transfers performed.
- In 2021, donor egg live births in US: 11,344 from 21,693 cycles.
- Asia-Pacific donor egg IVF grew 18% annually 2018-2023.
- 40% of donor egg cycles in 2022 US were PGT-A tested embryos.
- Israel reported 4,200 donor egg cycles in 2021, 30% of IVF.
- 2020 global donor egg shipments: 12,000+ via courier services.
- US clinics: average 45 donor egg cycles per clinic in 2021.
- 55% of 2022 donor egg transfers were single embryo transfers.
- Donor egg cycles in California 2021: 4,500, highest state.
- 28% increase in anonymous donor egg use 2019-2022.
- 2023 projected US donor egg cycles: 25,000+.
- Europe donor egg cycles: 70,000 in 2022.
- Fresh donor egg cycles declined 15% 2018-2022 in US.
- 12% of all US babies from ART in 2021 were from donor eggs.
- Donor egg IVF waitlists average 6-12 months in top US clinics 2023.
Usage Statistics Interpretation
Sources & References
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