Key Takeaways
- In a population-based case-control study involving 582 cases of vertebral artery dissection, chiropractic manipulation was associated with an odds ratio of 6.9 (95% CI 0.5-98.8) for dissection leading to stroke
- The incidence of vertebrobasilar stroke following chiropractic cervical manipulation was estimated at 1 in 5.85 million manipulations based on insurance claims data from 1995-2003
- Among 1,292,451 chiropractic upper cervical claims, 26 vertebrobasilar strokes occurred, yielding a rate of 2.01 per 100,000 claims (95% CI 1.39-2.92)
- Case series of 12 patients with quadriplegia from chiropractic cervical manipulation
- 1.8% incidence of transient neurological symptoms in 1,139 chiropractic patients post-treatment
- 21 cases of Brown-Sequard syndrome following chiropractic manipulation documented 1966-2004
- Fracture-dislocation of spine in 15 cases, 73% neurological deficit
- 1.1% incidence of rib fractures post-thoracic chiropractic in 839 patients
- 26 cases of vertebral fracture exacerbation from manipulation 1978-2012
- 53% of 39 cases had moderate-severe pain from soft tissue strain post-chiropractic
- Soreness lasting 24-48 hours in 56% of 325 patients after manipulation
- 27-55% mild AEs like local discomfort in multiple chiropractic trials meta-analysis
- 3.3% incidence of systemic reactions like fatigue post-chiropractic in surveys of 3,955 patients
- 25% of patients reported tiredness or kinesiophobia after first visit
- 1.4% nausea/vomiting in cervical manipulation RCTs meta-analysis
Chiropractic neck manipulation may rarely cause strokes and other serious injuries.






