Key Takeaways
- In the United States, approximately 240,000 coronary artery bypass graft (CABG) surgeries are performed annually, representing about 3% of all cardiovascular procedures.
- Globally, CABG accounts for over 800,000 procedures each year, with a 2.5% annual increase in low- and middle-income countries.
- The prevalence of CABG among patients over 65 years old is 1.2% per year in high-income countries.
- 25% of CABG patients have a family history of premature coronary artery disease.
- Hypertension is present in 85% of patients undergoing CABG surgery.
- Diabetes mellitus increases CABG risk by 40%, affecting 35% of candidates.
- Mean number of distal anastomoses in CABG is 3.2.
- Off-pump CABG constitutes 20% of all procedures in experienced centers.
- Internal mammary artery used in 95% of CABG surgeries as arterial graft.
- 30-day mortality rate for isolated CABG is 1.2%.
- Stroke incidence within 30 days post-CABG is 1.5-2%.
- Reoperation for bleeding occurs in 2-3% of CABG patients.
- 10-year freedom from repeat revascularization is 80%.
- LIMA graft patency at 10 years exceeds 90%.
- Overall 10-year survival post-CABG is 75%.
Coronary bypass surgery remains common globally with improving outcomes despite risks.
Complications
- Perioperative myocardial infarction rate is 3.1%.
- Mediastinitis occurs in 1-2% of CABG surgeries.
- Leg wound infection from vein harvest in 5-10%.
- Delirium post-op in 10-20% of elderly patients.
- Low cardiac output syndrome in 4-6%.
- Pleural effusion requiring drainage in 3%.
- Chylothorax rare at 0.5% incidence.
- Phrenic nerve injury causing diaphragm paralysis in 1-2%.
- Mesenteric ischemia post-CABG in 0.2-1%.
- Graft kinking or spasm in 1% of arterial grafts.
- Pneumothorax incidence 1-3% post-chest tubes.
- Vasoplegic syndrome in 20% of prolonged bypass cases.
- Hyperglycemia >180 mg/dL in 50% of diabetic patients.
- Tamponade requiring drainage in 1-2%.
- 90-day mortality is 2.5% for urgent CABG.
- Leg harvest neuropathy 5-10%.
- Hyperkalemia from cardioplegia 2%.
- Gut barrier dysfunction leading to sepsis 1%.
- Retinal artery embolism rare 0.1%.
- Thyroid storm in undiagnosed hyperthyroid 0.01%.
- Malignant hyperthermia 1:100,000.
- Air embolism to coronaries 0.2%.
- CO2 insufflation embolism in MIDCAB 1%.
- Donor site hernia 2%.
- Anaphylaxis to protamine 0.1-0.5%.
Complications Interpretation
Epidemiology
- In the United States, approximately 240,000 coronary artery bypass graft (CABG) surgeries are performed annually, representing about 3% of all cardiovascular procedures.
- Globally, CABG accounts for over 800,000 procedures each year, with a 2.5% annual increase in low- and middle-income countries.
- The prevalence of CABG among patients over 65 years old is 1.2% per year in high-income countries.
- In Europe, CABG surgery rates have declined by 15% from 2010 to 2020 due to increased PCI usage.
- Among Medicare beneficiaries, CABG utilization is highest in the Midwest US at 45 per 10,000 enrollees.
- In 2019, CABG was performed on 1.4% of all hospitalized patients with acute coronary syndrome.
- The incidence of CABG in diabetic patients is 2.5 times higher than in non-diabetics.
- CABG procedures represent 7% of all open-heart surgeries worldwide.
- In Asia, CABG volume grew by 28% between 2015 and 2020.
- US CABG rates per 100,000 population is 58 for men and 21 for women.
- In the United States, CABG surgeries peaked at 467,000 in 1999 before declining.
- CABG is indicated in 10-15% of stable angina patients with multivessel disease.
- In Canada, annual CABG volume is about 20,000 procedures.
- Among STEMI patients, 5% undergo CABG during index hospitalization.
Epidemiology Interpretation
Long-term Results
- 10-year freedom from repeat revascularization is 80%.
- LIMA graft patency at 10 years exceeds 90%.
- Overall 10-year survival post-CABG is 75%.
- CABG reduces all-cause mortality by 20% vs medical therapy at 5 years.
- Incidence of late stroke is 1.5% per patient-year.
- 5-year MACE rate is 15% lower with CABG than PCI in multivessel disease.
- Radial artery graft occlusion rate at 5 years is 10%.
- Heart failure hospitalization reduced by 30% at 5 years post-CABG.
- 20-year survival for CABG patients under 60 is 60-70%.
- Saphenous vein graft failure at 10 years is 40-50%.
- CABG improves quality of life scores by 25% at 1 year.
- Repeat CABG required in 5% within 10 years.
- Angina recurrence free in 85% at 5 years.
- Bilateral IMA improves 15-year survival by 15%.
- In diabetics, CABG halves mortality vs PCI at 5 years.
- 15-year survival 40%.
- Target vessel revascularization 12% at 5 years.
- LVEF improvement >5% in 40% of low EF patients.
- Cancer incidence similar to general population post-CABG.
- Neurocognitive decline persistent in 25% at 5 years.
- Allograft vasculopathy absent in CABG vs transplant.
- Employment return 50% at 1 year.
- LDL reduction to <70 mg/dL in 60% with statins.
- Sudden cardiac death 1% per year.
- Aortic valve replacement combined in 10%.
Long-term Results Interpretation
Perioperative Outcomes
- 30-day mortality rate for isolated CABG is 1.2%.
- Stroke incidence within 30 days post-CABG is 1.5-2%.
- Reoperation for bleeding occurs in 2-3% of CABG patients.
- Atrial fibrillation post-op affects 25-40% of patients.
- Acute kidney injury develops in 5-30% depending on risk score.
- Prolonged ventilation (>24 hours) in 5-10% of cases.
- Deep sternal wound infection rate is 0.5-1%.
- Myocardial infarction within 30 days is 2-4%.
- 5-year survival rate post-CABG is 85-90%.
- Graft patency at 1 year is 90% for LIMA and 75% for saphenous vein.
- Readmission rate within 30 days is 15%.
- EuroSCORE II predicts mortality with c-statistic of 0.81.
- STS risk score for mortality averages 1.8% in elective CABG.
- Off-pump vs on-pump shows similar 30-day mortality of 1.3%.
- 1-year mortality 1.8% per STS database.
- Renal failure requiring dialysis 1-2%.
- Sternal dehiscence 0.3%.
- VT/VF requiring defibrillation 5%.
- Transfusion rate 40-50%.
- Limb ischemia from IABP 0.5%.
- Operative mortality for isolated CABG 1.15%.
- 6-month survival 96%.
- Freedom from angina 88% at discharge.
- LOS median 7 days.
Perioperative Outcomes Interpretation
Procedure Details
- Mean number of distal anastomoses in CABG is 3.2.
- Off-pump CABG constitutes 20% of all procedures in experienced centers.
- Internal mammary artery used in 95% of CABG surgeries as arterial graft.
- Average operative time for CABG is 3-5 hours.
- Radial artery grafts utilized in 25% of multi-vessel CABG.
- Cardiopulmonary bypass time averages 90 minutes in on-pump CABG.
- Minimally invasive direct CABG (MIDCAB) performed in 5% of isolated LAD cases.
- Saphenous vein harvest via endoscopic method in 70% of cases.
- Bilateral internal mammary arteries used in 10-15% of diabetics.
- Total arterial revascularization achieved in 25% of CABG procedures.
- Hybrid CABG-PCI performed in 8% of multivessel disease patients.
- Robotic CABG adoption rate is 1-2% in high-volume centers.
- Aortic no-touch technique applied in 30% of off-pump surgeries.
- Hospital length of stay post-CABG averages 6-8 days.
- Anastomoses per patient average 3.7 in complex cases.
- Cross-clamp time averages 65 minutes.
- Skeletonized IMA harvest in 40% of arterial grafting.
- Composite Y-grafts used in 15% for total arterialization.
- Proximal anastomoses to aorta in 80% of vein grafts.
- OPCAB reduces transfusion needs by 50%.
- Endarterectomy performed in 5% of severely calcified vessels.
- Intra-aortic balloon pump used pre-op in 8%.
- Transit time flow measurement in 60% of centers.
- Hypothermic circulatory arrest rare <0.1%.
Procedure Details Interpretation
Recovery
- Return to work within 6 weeks in 70% of patients under 65.
- ICU stay averages 1-2 days post-CABG.
- Sternotomy healing takes 6-8 weeks.
- Cardiac rehab participation in 40-60% of patients.
- Pain scores decrease to baseline by 3 months.
- NYHA class improves by 1 grade in 80% at 6 months.
- Depression screened positive in 20% pre-op, resolves in 70% post.
- Exercise capacity increases 30% at 12 weeks.
- Driving resumption average 4-6 weeks post-surgery.
- Wound care complications in 10% of endoscopic harvest.
- Opioid use ceases by 4 weeks in 75%.
- Sexual activity resumes in 60% by 8 weeks.
- 1-year mortality post-discharge is 2%.
- Cost of CABG in US averages $100,000-$150,000.
- Functional status returns to baseline in 90% at 3 months.
- Anxiety scores halve by 6 months.
- Stair climbing tolerance doubles by discharge.
- Beta-blocker continuation 85% at 1 year.
- DAPT used in 20% post-CABG.
- Weight gain average 2-3 kg in first month.
- Sleep disturbance resolves in 80% by 3 months.
- Family caregiver burden peaks at 4 weeks.
- Vaccination rates post-op 70% for flu.
Recovery Interpretation
Risk Factors
- 25% of CABG patients have a family history of premature coronary artery disease.
- Hypertension is present in 85% of patients undergoing CABG surgery.
- Diabetes mellitus increases CABG risk by 40%, affecting 35% of candidates.
- Smoking history is reported in 60-70% of CABG patients.
- Obesity (BMI >30) is a comorbidity in 42% of elective CABG cases.
- Chronic kidney disease (eGFR <60) is found in 28% of CABG patients.
- Peripheral artery disease coexists in 20% of individuals selected for CABG.
- Age over 75 years elevates CABG perioperative mortality by 3-fold.
- Female gender is associated with 1.5 times higher CABG complication rates.
- Hyperlipidemia affects 75% of patients prior to CABG.
- Average age of CABG patients is 66 years, with 75% male.
- Left ventricular ejection fraction <35% is present in 15% of CABG candidates.
- Prior myocardial infarction history in 55% of CABG surgeries.
- Atrial fibrillation preoperatively in 12% of cases.
- 18% of CABG patients have had prior PCI.
- CABG utilization in octogenarians is 8% of total procedures.
- COPD (FEV1 <75%) present in 22% of CABG candidates.
- Prior stroke increases mortality risk 2-fold.
- Insulin-dependent diabetes in 20% of CABG patients.
- EuroSCORE >5 in 15% of elective cases.
- Mean SYNTAX score in CABG group is 28.
- Triple vessel disease in 70% of CABG indications.
- Left main stenosis >50% in 25% of patients.
- Emergency CABG comprises 10% of total volume.
- Proximal LAD stenosis in 85% of CABG cases.
Risk Factors Interpretation
Sources & References
- Reference 1CDCcdc.govVisit source
- Reference 2NCBIncbi.nlm.nih.govVisit source
- Reference 3HEARTheart.orgVisit source
- Reference 4ACADEMICacademic.oup.comVisit source
- Reference 5JAMANETWORKjamanetwork.comVisit source
- Reference 6ATSJOURNALSatsjournals.orgVisit source
- Reference 7DIABETESJOURNALSdiabetesjournals.orgVisit source
- Reference 8FRONTIERSINfrontiersin.orgVisit source
- Reference 9LINKlink.springer.comVisit source
- Reference 10AHAJOURNALSahajournals.orgVisit source
- Reference 11MAYOCLINICmayoclinic.orgVisit source
- Reference 12MYmy.clevelandclinic.orgVisit source
- Reference 13KIDNEYkidney.orgVisit source
- Reference 14JTCVSjtcvs.orgVisit source
- Reference 15STSsts.orgVisit source
- Reference 16EURJMEDRESeurjmedres.biomedcentral.comVisit source
- Reference 17JACCjacc.orgVisit source
- Reference 18SCAIscai.orgVisit source
- Reference 19CTSNETctsnet.orgVisit source
- Reference 20HOPKINSMEDICINEhopkinsmedicine.orgVisit source
- Reference 21CMScms.govVisit source
- Reference 22NEJMnejm.orgVisit source
- Reference 23CIHIcihi.caVisit source






