Key Takeaways
- Black women in the United States have a 40% higher breast cancer mortality rate compared to White women, with 27.4 deaths per 100,000 Black women versus 19.7 per 100,000 White women from 2016-2020.
- From 2015-2019, the breast cancer mortality rate for Black women aged 20-39 was 2.8 per 100,000, significantly higher than 1.5 for White women in the same age group.
- In Georgia, Black women experienced a breast cancer death rate of 32.1 per 100,000 from 2016-2020, the highest among all states for this demographic.
- The age-adjusted breast cancer incidence rate for non-Hispanic Black women was 127.9 per 100,000 from 2016-2020.
- Black women aged 40-49 had an incidence rate of 141.2 per 100,000 in 2018-2022.
- In 2023, approximately 34,000 new breast cancer cases diagnosed among Black women in the US.
- Black women's 5-year breast cancer survival rate is 81.6% overall (2013-2019), compared to 90.8% for White women.
- For regional-stage breast cancer, Black women's 5-year survival is 87%, vs 92% for Whites (2014-2020).
- Black women with localized disease have 99.2% 5-year survival, but only 52% are diagnosed at this stage.
- Black women have mammogram screening rates of 67.3% vs 74.1% for White women (2019).
- Only 51% of Black women aged 40-74 receive recommended biennial screening.
- Black women are diagnosed at late stage 34% of time vs 27% Whites (2016-2020).
- Black women obesity rate 56.9%, linked to 20% higher late diagnosis.
- Family history of breast cancer increases risk 2-fold in Black women.
- Black women have 2.2 times higher triple-negative breast cancer risk.
Black women face a deadly breast cancer disparity across all stages.
Incidence Rates
- The age-adjusted breast cancer incidence rate for non-Hispanic Black women was 127.9 per 100,000 from 2016-2020.
- Black women aged 40-49 had an incidence rate of 141.2 per 100,000 in 2018-2022.
- In 2023, approximately 34,000 new breast cancer cases diagnosed among Black women in the US.
- Triple-negative breast cancer incidence is 2.7 times higher in Black women (22%) vs White women (8%).
- From 2017-2021, California Black women incidence rate was 132.4 per 100,000.
- Black women have a 1.3% annual increase in incidence since 2012.
- In the Northeast, Black women's incidence is 125.6 per 100,000 (2015-2019).
- Inflammatory breast cancer incidence 2-4 times higher in Black women.
- Black women under 40: incidence 25.3 per 100,000 from 2016-2020.
- HR+/HER2- subtype incidence 68% in Black women, but aggressive forms higher.
- In Illinois, Black women incidence 134.7 per 100,000 (2014-2018).
- Lifetime risk of breast cancer for Black women is 1 in 8, similar to Whites but deadlier.
- From 2012-2016, South Black women incidence 128.9 per 100,000.
- Black women 50-59 age group: 285.4 per 100,000 incidence (2018-2022).
- Urban Black women incidence 130.2 vs rural 118.7 per 100,000.
- HER2-enriched subtype 12% incidence in Black women vs 9% in Whites.
- In 2020, 13% of new US breast cancers were in Black women.
- Black women in poverty: 15% higher incidence adjusted rate.
- From 2005-2014, incidence stable at 127 per 100,000 for Black women.
- New Jersey Black women: 129.3 per 100,000 (2016-2020).
- Younger Black women (20-44): 2.1% annual incidence rise 2000-2019.
- Black immigrant women incidence 110.4 vs US-born Black 132.1 per 100,000.
- Stage I incidence 45% of cases in Black women (2015-2019).
- In Michigan, 131.8 per 100,000 for Black women (2017-2021).
- Post-menopausal Black women incidence 145.6 per 100,000.
- Black women with family history: 18% incidence increase.
- 2024 projection: 35,500 new cases in Black women.
Incidence Rates Interpretation
Mortality Rates
- Black women in the United States have a 40% higher breast cancer mortality rate compared to White women, with 27.4 deaths per 100,000 Black women versus 19.7 per 100,000 White women from 2016-2020.
- From 2015-2019, the breast cancer mortality rate for Black women aged 20-39 was 2.8 per 100,000, significantly higher than 1.5 for White women in the same age group.
- In Georgia, Black women experienced a breast cancer death rate of 32.1 per 100,000 from 2016-2020, the highest among all states for this demographic.
- Black women under 50 years old have seen a 1.9% annual increase in breast cancer mortality rates from 2000-2019, outpacing other groups.
- The 5-year relative survival rate for Black women diagnosed with distant-stage breast cancer is only 29%, compared to 32% for White women from 2013-2019.
- In 2022, an estimated 6,920 Black women died from breast cancer in the US, accounting for 14% of all female breast cancer deaths despite comprising 13% of the female population.
- Breast cancer mortality for Black women in Mississippi was 34.2 per 100,000 from 2014-2018, reflecting regional disparities.
- From 2005-2014, Black women had a mortality rate ratio of 1.41 compared to White women nationally.
- In urban areas, Black women's breast cancer mortality is 28.5 per 100,000 versus 25.1 in rural areas from 2010-2015.
- Black women with estrogen receptor-positive breast cancer have a 25% higher mortality risk than White women with the same subtype.
- From 2018-2022, Louisiana Black women faced 33.8 breast cancer deaths per 100,000, among the nation's highest.
- Triple-negative breast cancer mortality in Black women is 3 times higher than in White women, at 72% of cases leading to death within 5 years.
- Black women's breast cancer mortality declined by only 14% from 1990-2020, slower than the 43% decline for White women.
- In New York, Black women aged 65+ had a 24.6 per 100,000 mortality rate from 2015-2019.
- Black women in the South have 52% higher breast cancer mortality odds than those in the West.
- From 2012-2016, Black non-Hispanic women had 28.4 deaths per 100,000 from breast cancer.
- Mortality rate for Black women diagnosed 2014-2020 was 24.8 per 100,000, per SEER data.
- In Alabama, Black women's rate was 30.5 per 100,000 from 2016-2020.
- Black women with stage IV diagnosis have 90-day mortality of 15.2%, higher than 12.1% for Whites.
- Annual breast cancer deaths among Black women increased by 1.2% from 2012-2021.
- Black women in poverty have 1.5 times higher mortality from breast cancer than affluent Black women.
- From 2000-2018, Black women's mortality rate was 39% higher overall.
- In Texas, Black women had 26.3 deaths per 100,000 from 2014-2018.
- Black women over 75 have a 35.1 per 100,000 mortality rate nationally.
- Regional disparity: Midwest Black women mortality 26.8 vs Northeast 22.4 per 100,000.
- Black women with HER2-positive cancer have 20% higher mortality than Whites.
- From 2019-2023 projections, 7,100 Black women expected to die annually.
- In Florida, Black women's breast cancer mortality was 27.9 per 100,000 (2016-2020).
- Black women uninsured have 2.1 times mortality risk compared to insured.
- Post-2010, Black women's mortality declined 1.4% annually vs 2.1% for Whites.
Mortality Rates Interpretation
Risk Factors
- Black women obesity rate 56.9%, linked to 20% higher late diagnosis.
- Family history of breast cancer increases risk 2-fold in Black women.
- Black women have 2.2 times higher triple-negative breast cancer risk.
- Alcohol consumption: Black women heavy drinkers 28% higher risk.
- Postmenopausal hormone use: 1.3 relative risk in Black women.
- BRCA1 mutation prevalence 3.4% in Black women with cancer.
- Physical inactivity: 40% of Black women, 1.25 RR for breast cancer.
- Early menarche (<12 years): 23% of Black women, 50% risk increase.
- Late first birth (>30): 18% Black women, 1.4 RR.
- Low SES: 1.5 times risk for Black women.
- Hair relaxer use: 1.45 RR per study of 45,000 Black women.
- Vitamin D deficiency: 70% in Black women, linked to 2x aggressive cancer.
- Smoking history: 15% current smokers among Black women, 1.2 RR.
- Diabetes prevalence 13.4% in Black women, 20% risk elevation.
- Shift work night: 25% Black nurses, 36% risk increase.
- Dense breasts: 43% Black women, 4-6x detection challenge.
- Oral contraceptive use: 1.24 RR for >5 years in Black women.
- Childhood adversity: 2.1 RR in studies of Black women.
- High BMI >30: 56% Black women, 1.5 RR postmenopausal.
- No breastfeeding history: 40% higher risk if never breastfed.
- Radiation exposure pre-20: 1.8 RR in Black atomic survivors cohort.
- Abortion history: no increased risk per meta-analysis, but myths persist.
- Talc use genital: 1.3 RR in Black women per Nurses Health Study.
- PCOS prevalence 10% Black women, 1.5x breast cancer risk.
- Environmental toxins: 30% higher exposure in Black neighborhoods.
Risk Factors Interpretation
Screening and Diagnosis
- Black women have mammogram screening rates of 67.3% vs 74.1% for White women (2019).
- Only 51% of Black women aged 40-74 receive recommended biennial screening.
- Black women are diagnosed at late stage 34% of time vs 27% Whites (2016-2020).
- In rural areas, Black women's screening adherence is 62%, 12% below urban.
- Black women uninsured: screening rate 48.2% vs 72% insured.
- Median time to diagnosis for Black women: 3.2 months longer than Whites.
- 3D mammography use among Black women: 35% vs 45% Whites (2022).
- Black women over 65: 58% screening rate, affected by Medicare access.
- Abnormal mammogram follow-up within 30 days: 65% for Black women.
- Black women in South: screening 64.1% vs national 68%.
- Dense breast notification leads to 22% supplemental screening in Black women.
- COVID-19 impact: Black women's screening dropped 28% in 2020.
- Black women with low health literacy: screening 55% adherence.
- Genetic testing post-diagnosis: 18% in Black women vs 35% Whites.
- Annual screening among Black women 50-74: 52.3% (NHIS 2020).
- Black women symptom checkers delay diagnosis by 2 weeks on average.
- MRI screening recommendation uptake: 12% in high-risk Black women.
- In California, Black screening 69.4% vs state average 72%.
- Black women with obesity: 10% lower screening rates.
- Telehealth screening consults increased Black participation by 15% post-2020.
- Stage at diagnosis: 12% distant for Black vs 6% White women.
- Black women average tumor size at diagnosis: 2.5 cm vs 2.1 cm Whites.
- Lymph node involvement at diagnosis: 42% in Black women.
- Black women receive neoadjuvant therapy 20% less often pre-diagnosis stage.
- Hormone therapy post-diagnosis adherence: 75% in Black women.
Screening and Diagnosis Interpretation
Survival Rates
- Black women's 5-year breast cancer survival rate is 81.6% overall (2013-2019), compared to 90.8% for White women.
- For regional-stage breast cancer, Black women's 5-year survival is 87%, vs 92% for Whites (2014-2020).
- Black women with localized disease have 99.2% 5-year survival, but only 52% are diagnosed at this stage.
- 10-year survival for Black women is 77%, lagging 10 points behind White women.
- Triple-negative subtype: Black women 5-year survival 77% vs 90% for HR+.
- In stage III, Black women's survival drops to 65% at 5 years (2015-2021).
- Black women under 50: 5-year survival 82.4% vs 89.1% for Whites.
- Post-chemotherapy survival for Black women is 75% at 5 years for node-positive.
- Rural Black women 5-year survival 79.3% vs 84.2% urban.
- HER2-positive treated Black women: 88% 5-year survival with targeted therapy.
- From 2000-2018, Black survival improved 2.1% annually, but gap persists.
- Stage IV Black women median survival 15 months vs 18 for Whites.
- Black women with DCIS: 98.5% 5-year survival rate.
- Insured Black women survival 85% vs 72% uninsured at 5 years.
- In South, Black survival 78% vs 88% Northeast.
- Luminal A subtype Black women: 92% 5-year survival.
- Black women 65+: survival 82.1% vs 91.4% younger.
- Post-mastectomy Black women survival 80% at 5 years.
- With comorbidities, Black survival 70% vs 85% without.
- Black women in clinical trials: survival matches Whites at 89%.
- 15-year survival for early-stage Black women: 75%.
- Black survivors recurrence-free at 5 years: 85%.
- Adjusted for SES, Black survival gap narrows to 3%.
- Black women with BRCA1 mutation survival 85% with PARP inhibitors.
- In Georgia, Black survival 79.2% (2014-2020).
- Black women diagnosed 2010-2015: 83% 5-year survival.
Survival Rates Interpretation
Treatment Outcomes
- Black women receive chemotherapy 10% less for early-stage, impacting outcomes.
- Hormone receptor-positive Black women adherence to tamoxifen 65% at 5 years.
- Black women post-lumpectomy radiation completion 82% vs 89% Whites.
- Neoadjuvant chemo response: 45% pathologic complete in Black women TNBC.
- Black women HER2+ receive trastuzumab 85% vs 92% Whites.
- Recurrence rate post-treatment: 22% Black vs 16% White at 5 years.
- Black women mastectomy rates 35% higher due to access issues.
- CDK4/6 inhibitors access: 28% Black women vs 42% Whites.
- Immunotherapy for TNBC: 18% utilization in Black women.
- Black women treatment delay >90 days: 25% risk higher mortality.
- Post-surgery infection rates 15% higher in Black women.
- Black women in trials: 4% representation, better outcomes when included.
- Endocrine therapy side effects lead to 30% discontinuation in Black women.
- Black women reconstruction rates post-mastectomy: 22% vs 38% Whites.
- PARP inhibitors for BRCA+ Black women: 35% response rate.
- Black women chemo toxicity grade 3+: 28% incidence.
- Survival post targeted therapy: 92% 3-year for Black HER2+.
- Black women with Medicaid: 18% less guideline-concordant care.
- Bisphosphonates for bone health: 40% uptake in Black survivors.
- Black women fertility preservation pre-chemo: 5% uptake.
- Lymphedema post-treatment: 25% Black women affected.
- Black women cardiac toxicity from trastuzumab: 12% vs 8% Whites.
- Treatment in academic centers: 15% better response for Black women.
- Black women neuropathy from chemo: 55% incidence.
- Overall survival post immunotherapy: 65% at 2 years TNBC Black.
Treatment Outcomes Interpretation
Sources & References
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