Top 10 Best Usb Lock Software of 2026

Endpoint Protector by Cososys is a leading Data Loss Prevention (DLP) solution specializing in USB device control and endpoint security. It enables granular locking of USB ports and devices through whitelisting, blacklisting, and policy enforcement based on user roles, device IDs, content types, and serial numbers. Supporting Windows, macOS, and Linux, it goes beyond basic blocking with features like content scanning, data shadowing, and virtual device conversion for controlled access.

DeviceLock is an enterprise-grade USB and device control solution that prevents unauthorized data transfers via USB ports, peripherals, Bluetooth, and network shares. It provides granular policies to block or allow specific devices, users, or content types, while capturing forensic copies of transferred data through its Shadow feature. With centralized management via Group Policy or console, it excels in compliance auditing and data leakage prevention for Windows environments.

GiliSoft USB Lock is a Windows-based security application that prevents unauthorized data transfer by locking USB ports and restricting access to removable drives, CDs/DVDs, printers, and other peripherals. It offers password protection, device whitelisting, and scheduling features to enable flexible control over hardware access. Additionally, it includes options to block internet access, specific folders, and certain programs, making it a versatile locking solution for data protection.

FSPro USB Lock is a Windows-focused security software that prevents unauthorized data transfer by locking USB ports and controlling access to external devices like flash drives, printers, and CD/DVDs. It offers whitelisting, blacklisting, password protection, and detailed activity logging to help organizations combat data leaks. The tool supports both local and network-wide deployment, with options for silent blocking and custom policies.

USB Lock PC is a Windows-based security tool that locks down USB ports and removable media to prevent data leakage and unauthorized access. It offers features like device blacklisting/whitelisting, password-protected controls, activity logging, and centralized network management for multiple PCs. Ideal for businesses aiming to secure endpoints against USB drive misuse, it supports blocking USB storage, CD/DVD drives, Bluetooth devices, and more.

1st USB Lock All is a Windows-based security tool that blocks access to USB storage devices, CD/DVD drives, and Bluetooth ports to prevent data leakage and unauthorized copying. It features password protection, device whitelisting for trusted hardware, and runs as a hidden system service for stealthy operation. Ideal for endpoint protection in small networks, it supports centralized management via group policies.

USB Disk Security is a lightweight antivirus tool focused on protecting Windows PCs from malware threats originating from USB drives. It blocks autorun viruses, disables unsafe USB functions, and allows users to control access to USB storage devices through whitelisting or blocking. The software operates in the background with minimal resource usage, providing real-time safeguards against common USB-based attacks.

Panda USB Vaccine is a free, portable utility from Panda Security that protects Windows computers from autorun malware by disabling the autorun feature on USB drives and local fixed drives. It offers two modes: vaccinating a specific USB drive to make it immune or vaccinating the entire computer for broader protection. While effective against autorun infector viruses, it does not provide comprehensive USB port locking or block data transfer.

VeraCrypt is a free, open-source disk encryption tool that creates virtual encrypted disks and can fully encrypt physical drives, including USB sticks, securing data behind strong passwords. It allows users to mount USB drives as encrypted volumes accessible only with the correct key, protecting against unauthorized access. The software supports advanced features like hidden volumes for plausible deniability and works across Windows, macOS, and Linux.

Folder Lock by NewSoftwares.net is a multi-purpose security tool that primarily focuses on password-protecting and encrypting files and folders on local drives. For USB locking, it offers the ability to lock entire USB drives and external storage devices, requiring a master password for access, along with support for portable encrypted lockers stored on USBs. While effective for securing data on removable media, it is more of a general file locker than a dedicated USB port blocker.