Top 10 Best Surgery Software of 2026

Epic OpTime is a leading perioperative module within the Epic EHR platform, designed to streamline surgical workflows from pre-op scheduling to post-op recovery. It provides comprehensive tools for operating room management, intraoperative documentation, anesthesia tracking, and inventory control. As part of Epic's integrated ecosystem, OpTime ensures real-time data sharing across clinical teams, enhancing efficiency and patient safety in high-volume surgical environments.

Cerner SurgiNet is a robust perioperative software solution from Cerner that streamlines surgical workflows across the continuum of care, from preoperative planning and scheduling to intraoperative management and postoperative tracking. It integrates deeply with Cerner's Millennium EHR platform, enabling seamless access to patient data, anesthesia documentation, inventory management, and supply chain optimization. Designed for large-scale healthcare systems, it provides advanced analytics for OR utilization, case costing, and performance benchmarking to improve efficiency and outcomes.

Surgical Information Systems (SIS) offers a comprehensive perioperative software suite designed specifically for hospitals and ambulatory surgery centers (ASCs), covering everything from scheduling and inventory management to clinical documentation and analytics. It streamlines surgical workflows, ensures regulatory compliance, and provides real-time insights to optimize operating room efficiency. SIS is widely used in the U.S. for its robust integration with EHRs and focus on perioperative data management.

Picis provides the Perioperative CareSuite, a comprehensive software platform designed specifically for surgical environments, including anesthesia information management (AIMS), perioperative scheduling, inventory management, and compliance reporting. It streamlines workflows from pre-op to post-op, enabling real-time data capture and integration with EHR systems. Targeted at hospitals and ambulatory surgery centers, it enhances OR efficiency and patient safety through advanced analytics and automation.

Brainlab offers a suite of digital surgery software solutions focused on image-guided surgery, including preoperative planning with iPlan, intraoperative navigation via Curve and Kick systems, and visualization tools for neurosurgery, spine, orthopedics, and ENT procedures. The platform integrates multimodal imaging, AI-driven planning, and mixed reality to enhance surgical precision and workflow efficiency. It supports everything from trajectory planning to real-time navigation and postoperative documentation, reducing risks in complex interventions.

Stryker Mako is a robotic-assisted surgery platform specializing in orthopedic procedures like total knee, hip, and partial knee replacements. It combines CT-based 3D preoperative planning software with an intelligent robotic arm for real-time intraoperative guidance, enabling sub-millimeter accuracy in bone preparation and implant positioning. The system uses haptic feedback to assist surgeons in staying within planned boundaries, improving surgical precision and patient outcomes.

Medtronic StealthStation is a sophisticated surgical navigation system designed for precise, image-guided procedures in neurosurgery, spine surgery, ENT, and orthopedics. It integrates preoperative CT, MRI, and other imaging data with real-time intraoperative tracking to provide surgeons with 3D visualization and instrument guidance. The platform supports optical and electromagnetic tracking technologies, automatic registration, and augmented reality features to enhance accuracy and workflow efficiency during minimally invasive surgeries.

Touch Surgery is a mobile app providing interactive 3D simulations of over 200 surgical procedures, allowing medical students, residents, and surgeons to practice step-by-step operations virtually. It includes detailed anatomical models, voiceover instructions, quizzes, and performance analytics to enhance learning and retention. Primarily designed for preoperative training, it supports self-paced education across specialties like orthopedics, neurosurgery, and general surgery.

Surgical Theater is an advanced surgical planning platform that converts patient-specific MRI and CT scans into immersive 3D anatomical models. Surgeons use VR headsets to rehearse procedures, explore complex anatomy from any angle, and simulate surgeries for better precision and confidence. The software integrates with navigation systems to guide real-time operations, primarily targeting neurosurgery, spine, and cranial procedures.

OsiriX MD is a powerful DICOM workstation and medical imaging viewer tailored for radiology and surgical planning on macOS. It provides advanced 2D/3D/4D visualization, multi-planar reconstruction, volume rendering, and image fusion for modalities like CT, MRI, and PET. Surgeons use it primarily for pre-operative planning, 3D modeling, and image analysis to support procedures such as neurosurgery, orthopedics, and vascular surgery.