Top 10 Best Supply Chain Network Design Software of 2026

Coupa Supply Chain Design, powered by the former Llamasoft technology, is an advanced platform for strategic supply chain network optimization, enabling users to model complex networks, simulate scenarios, and optimize facility locations, transportation, and inventory placement. It leverages AI, machine learning, and prescriptive analytics to minimize costs, enhance resilience, and support what-if analyses across global supply chains. Seamlessly integrated with Coupa's procurement and spend management suite, it provides real-time data synchronization for holistic decision-making.

Blue Yonder Supply Chain Design is an advanced optimization platform that models, simulates, and optimizes global supply chain networks, supporting decisions on facility locations, capacity planning, and transportation routes. Leveraging mathematical programming, AI, and machine learning, it enables multi-scenario analysis for cost reduction, service improvement, and risk mitigation. It integrates seamlessly with Blue Yonder's broader supply chain management suite for end-to-end planning and execution.

o9 Solutions' Digital Brain is an AI-powered platform designed for end-to-end supply chain planning, with robust capabilities in supply chain network design including optimization, scenario modeling, and simulation. It enables users to design and optimize global networks by considering factors like cost, service levels, sustainability, and risk across multi-echelon structures. The platform integrates advanced graph-based modeling and ML-driven insights for strategic decision-making, providing a digital twin of the supply chain for real-time what-if analysis.

Kinaxis RapidResponse is an enterprise-grade supply chain orchestration platform that provides advanced capabilities for network design, optimization, and concurrent planning across global supply chains. It enables users to model complex networks, run what-if scenarios, and optimize multi-echelon inventory and logistics in real-time using integrated data analytics. The platform stands out for its ability to handle volatility and uncertainty, supporting strategic network redesign alongside tactical execution.

SAP Integrated Business Planning (IBP) is a cloud-based platform that supports end-to-end supply chain planning, with robust capabilities for supply chain network design through modeling, optimization, and scenario simulation. It enables users to optimize facility locations, transportation networks, inventory positioning, and sourcing strategies using advanced mathematical solvers and heuristics. Integrated seamlessly with SAP S/4HANA and other SAP tools, it provides real-time data-driven insights for strategic network decisions across global operations.

Oracle Fusion Cloud SCM is a robust cloud-based supply chain management suite that includes advanced network design and optimization capabilities within its planning modules. It allows users to model multi-echelon supply chain networks, perform what-if scenario simulations, and optimize locations, capacities, flows, and inventory strategies. Integrated AI and machine learning enhance demand sensing and constraint-based planning for resilient operations.

AIMMS is an advanced algebraic modeling platform designed for optimization problems, particularly excelling in supply chain network design through custom mathematical models for facility location, transportation optimization, and multi-echelon planning. It integrates with leading solvers like CPLEX and Gurobi, allowing users to build, solve, and analyze complex strategic scenarios. The software supports both desktop and cloud deployment, with pre-built apps accelerating supply chain-specific implementations.

AnyLogic is a multimethod simulation platform that supports agent-based, discrete event, and system dynamics modeling for designing and optimizing supply chain networks. It enables detailed simulations of logistics, inventory management, production, and distribution to evaluate scenarios for cost, efficiency, and risk. Users can build custom models to test network configurations and what-if analyses.

River Logic Enterprise Optimizer (EPO) is a prescriptive analytics platform specializing in advanced optimization for supply chain network design, leveraging a unique multi-dimensional modeling language to handle complex, non-linear constraints and business rules. It enables strategic scenario planning, facility location optimization, transportation network design, and inventory balancing across global supply chains. EPO stands out for its ability to integrate prescriptive analytics with operational execution, providing actionable insights beyond traditional linear programming solvers.

OMP+ is an enterprise-grade supply chain optimization platform from OMP that specializes in advanced network design, enabling modeling and optimization of complex, multi-echelon supply chains. It leverages powerful mathematical programming solvers to determine optimal facility locations, capacities, transportation routes, and inventory policies under various scenarios. The software supports strategic planning with what-if analysis, integrating data from ERP systems for holistic decision-making across industries like chemicals, food, and pharmaceuticals.