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Top 10 Best Sample Management Software of 2026

Discover top 10 sample management software to streamline workflows. Compare features & find your ideal fit today.

Sarah Mitchell

Sarah Mitchell

Feb 11, 2026

10 tools comparedExpert reviewed
Independent evaluation · Unbiased commentary · Updated regularly
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Effective sample management is foundational to streamlining lab operations, ensuring data integrity, and meeting regulatory standards across industries. With a range of solutions—from enterprise LIMS to cloud-native R&D platforms—choosing the right tool can elevate efficiency, and our curated list of the top 10 options helps professionals navigate this landscape.

Quick Overview

  1. 1#1: LabWare LIMS - Comprehensive enterprise LIMS for end-to-end sample lifecycle management, workflow automation, and regulatory compliance in laboratories.
  2. 2#2: STARLIMS - Flexible, configurable LIMS platform for sample tracking, testing workflows, and quality assurance across industries.
  3. 3#3: Thermo Scientific SampleManager - Integrated LIMS solution for biopharma sample management, data integrity, and instrument integration.
  4. 4#4: LabVantage - Unified lab informatics platform with robust LIMS for sample inventory, chain-of-custody, and analytics.
  5. 5#5: Benchling - Cloud-native R&D platform for biotech sample tracking, request management, and collaborative workflows.
  6. 6#6: Dotmatics - Scientific informatics suite with LIMS for sample registration, storage, and assay data management.
  7. 7#7: Labguru - All-in-one ELN and LIMS for sample management, experiment tracking, and lab operations.
  8. 8#8: QBench - Cloud-based LIMS for efficient sample accessioning, workflow orchestration, and reporting in testing labs.
  9. 9#9: CloudLIMS - Secure SaaS LIMS for sample lifecycle management, compliance, and real-time collaboration.
  10. 10#10: SciCord - Document-centric LIMS for sample management, batch records, and GMP compliance in manufacturing.

We ranked tools based on key factors including feature depth (workflow automation, compliance support, integration capabilities), user experience (intuitiveness, scalability), and practical value (alignment with niche needs like biotech or manufacturing) to provide a trusted resource for decision-making.

Comparison Table

Navigate the landscape of sample management software with this comparison table, featuring standout tools like LabWare LIMS, STARLIMS, Thermo Scientific SampleManager, LabVantage, Benchling, and others. Readers will explore key features, workflow design, and integration capabilities to identify the right solution for their lab or research workflows.

Comprehensive enterprise LIMS for end-to-end sample lifecycle management, workflow automation, and regulatory compliance in laboratories.

Features
9.8/10
Ease
8.1/10
Value
8.7/10
2STARLIMS logo9.2/10

Flexible, configurable LIMS platform for sample tracking, testing workflows, and quality assurance across industries.

Features
9.6/10
Ease
8.0/10
Value
8.8/10

Integrated LIMS solution for biopharma sample management, data integrity, and instrument integration.

Features
9.3/10
Ease
7.2/10
Value
8.0/10
4LabVantage logo8.7/10

Unified lab informatics platform with robust LIMS for sample inventory, chain-of-custody, and analytics.

Features
9.4/10
Ease
7.8/10
Value
8.2/10
5Benchling logo8.5/10

Cloud-native R&D platform for biotech sample tracking, request management, and collaborative workflows.

Features
9.2/10
Ease
8.0/10
Value
7.8/10
6Dotmatics logo8.4/10

Scientific informatics suite with LIMS for sample registration, storage, and assay data management.

Features
9.2/10
Ease
7.6/10
Value
8.0/10
7Labguru logo7.9/10

All-in-one ELN and LIMS for sample management, experiment tracking, and lab operations.

Features
8.2/10
Ease
8.0/10
Value
7.5/10
8QBench logo8.3/10

Cloud-based LIMS for efficient sample accessioning, workflow orchestration, and reporting in testing labs.

Features
8.7/10
Ease
8.0/10
Value
7.9/10
9CloudLIMS logo8.2/10

Secure SaaS LIMS for sample lifecycle management, compliance, and real-time collaboration.

Features
8.6/10
Ease
7.7/10
Value
8.0/10
10SciCord logo8.1/10

Document-centric LIMS for sample management, batch records, and GMP compliance in manufacturing.

Features
8.5/10
Ease
7.9/10
Value
7.7/10
1
LabWare LIMS logo

LabWare LIMS

enterprise

Comprehensive enterprise LIMS for end-to-end sample lifecycle management, workflow automation, and regulatory compliance in laboratories.

Overall Rating9.5/10
Features
9.8/10
Ease of Use
8.1/10
Value
8.7/10
Standout Feature

Zero-footprint web-based client with a powerful rules-based engine for fully customizable sample workflows without programming

LabWare LIMS is a leading enterprise-grade Laboratory Information Management System (LIMS) that excels in comprehensive sample management, tracking samples from receipt, processing, storage, and disposal across diverse lab environments. It provides robust features for inventory control, chain-of-custody documentation, barcode/RFID tracking, and integration with lab instruments and ERP systems. Designed for regulated industries like pharmaceuticals, biotech, food & beverage, and environmental testing, it ensures compliance with standards such as FDA 21 CFR Part 11, ISO 17025, and GxP.

Pros

  • Unparalleled configurability with zero-code customization for complex sample workflows
  • Superior sample tracking, lineage, and inventory management with real-time visibility
  • Seamless integration with hundreds of instruments and strong regulatory compliance tools

Cons

  • Steep learning curve and extensive configuration time for optimal setup
  • High upfront implementation and customization costs
  • Requires IT expertise for deployment and maintenance

Best For

Large-scale, regulated laboratories in pharma, biotech, or environmental sectors needing highly scalable and customizable sample management.

Pricing

Quote-based enterprise pricing; typically $50,000+ annually depending on modules, users, and deployment scale, with perpetual licenses available.

2
STARLIMS logo

STARLIMS

enterprise

Flexible, configurable LIMS platform for sample tracking, testing workflows, and quality assurance across industries.

Overall Rating9.2/10
Features
9.6/10
Ease of Use
8.0/10
Value
8.8/10
Standout Feature

No-code configuration engine for building custom workflows and sample management rules without programming

STARLIMS is a leading Laboratory Information Management System (LIMS) from Abbott Informatics, specializing in end-to-end sample management for laboratories in regulated industries like pharmaceuticals, biotech, and food safety. It handles the full sample lifecycle, from accessioning and tracking to testing, storage, and disposal, with seamless integration to lab instruments and ERP systems. The platform emphasizes data integrity, compliance with standards like 21 CFR Part 11 and ISO 17025, and customizable workflows to optimize lab efficiency.

Pros

  • Highly configurable workflows for complex sample processes
  • Strong instrument integration and automation capabilities
  • Excellent compliance and audit trail features for regulated environments

Cons

  • Complex and time-intensive implementation process
  • High cost suitable mainly for enterprises
  • Steep learning curve for non-technical users

Best For

Large enterprise laboratories in pharmaceuticals, biotech, or clinical testing requiring scalable, compliant sample management.

Pricing

Custom quote-based pricing; typically $100,000+ annually for mid-sized deployments, scaling with modules, users, and customization.

Visit STARLIMSstarlims.com
3
Thermo Scientific SampleManager logo

Thermo Scientific SampleManager

enterprise

Integrated LIMS solution for biopharma sample management, data integrity, and instrument integration.

Overall Rating8.7/10
Features
9.3/10
Ease of Use
7.2/10
Value
8.0/10
Standout Feature

Deep, native integration with Thermo Scientific instruments for automated data capture and reduced manual errors

Thermo Scientific SampleManager is a robust Laboratory Information Management System (LIMS) designed for comprehensive sample lifecycle management in regulated laboratory environments. It automates workflows from sample registration, tracking, and processing to storage and disposal, with seamless integration to lab instruments and enterprise systems. The software ensures data integrity, compliance with standards like FDA 21 CFR Part 11, and provides real-time analytics for efficient decision-making in pharma, biotech, and clinical labs.

Pros

  • Extensive integration with Thermo Fisher instruments and third-party systems
  • Strong compliance and audit trail capabilities for regulated industries
  • Highly customizable workflows and scalable for enterprise-level operations

Cons

  • Steep learning curve and complex initial setup
  • High implementation and customization costs
  • Interface can feel dated compared to modern SaaS alternatives

Best For

Enterprise laboratories in pharmaceuticals, biotech, or clinical research needing robust, compliant sample management at scale.

Pricing

Enterprise pricing via custom quote; typically perpetual licenses starting at $100,000+ with annual maintenance fees, or subscription models from $50,000/year depending on deployment.

4
LabVantage logo

LabVantage

enterprise

Unified lab informatics platform with robust LIMS for sample inventory, chain-of-custody, and analytics.

Overall Rating8.7/10
Features
9.4/10
Ease of Use
7.8/10
Value
8.2/10
Standout Feature

Visual Workflow Designer enabling no-code creation of complex, automated sample processing workflows

LabVantage is a comprehensive Laboratory Information Management System (LIMS) that provides robust sample management capabilities for tracking samples throughout their lifecycle in research, clinical, pharmaceutical, and manufacturing labs. It supports automated workflows, inventory management, chain-of-custody tracking, and integration with lab instruments for seamless data capture. The platform emphasizes regulatory compliance with features like audit trails and electronic signatures, making it suitable for highly regulated environments.

Pros

  • Advanced sample lineage and chain-of-custody tracking
  • Highly customizable no-code workflows and configurations
  • Strong regulatory compliance tools including 21 CFR Part 11 support

Cons

  • Steep learning curve and extensive training required
  • Complex implementation process for enterprise deployments
  • High cost prohibitive for small labs

Best For

Large-scale laboratories in regulated industries like pharma and biotech needing scalable, compliant sample management.

Pricing

Custom enterprise pricing; typically starts at $50,000+ annually for subscriptions, scaling with users, modules, and deployment size.

Visit LabVantagelabvantage.com
5
Benchling logo

Benchling

specialized

Cloud-native R&D platform for biotech sample tracking, request management, and collaborative workflows.

Overall Rating8.5/10
Features
9.2/10
Ease of Use
8.0/10
Value
7.8/10
Standout Feature

Interactive sample lineage graphs that trace parent-child relationships and full provenance history

Benchling is a cloud-based life sciences R&D platform with robust sample management features, enabling users to track samples, manage inventory, monitor storage conditions, and visualize lineages across experiments. It integrates sample data with electronic lab notebooks, protocols, and collaboration tools for end-to-end workflow management. Designed for biotech and pharma teams, it supports scalable operations from research to manufacturing.

Pros

  • Advanced sample lineage tracking and visualization
  • Seamless integration with ELNs and protocols
  • Real-time inventory monitoring with alerts

Cons

  • Steep learning curve for new users
  • Enterprise pricing can be prohibitive for small labs
  • Limited offline access

Best For

Mid-to-large biotech and pharma teams requiring integrated sample tracking within broader R&D workflows.

Pricing

Custom enterprise pricing starting around $100-200/user/month; free tier for academic and non-commercial use.

Visit Benchlingbenchling.com
6
Dotmatics logo

Dotmatics

enterprise

Scientific informatics suite with LIMS for sample registration, storage, and assay data management.

Overall Rating8.4/10
Features
9.2/10
Ease of Use
7.6/10
Value
8.0/10
Standout Feature

Unified platform integration linking samples directly to experimental data and analytics for full lifecycle visibility

Dotmatics is a comprehensive scientific informatics platform with robust sample management capabilities via its Inventory module, enabling precise tracking, storage, and retrieval of biological and chemical samples. It supports barcode scanning, automated workflows, hierarchical location management, and seamless integration with ELNs, LIMS, and analytics tools. Designed for life sciences R&D, it ensures regulatory compliance, real-time visibility, and scalability for large inventories.

Pros

  • Extensive integration with ELN, assays, and data platforms for end-to-end workflows
  • Advanced tracking with RFID/barcode, expiry alerts, and audit trails for compliance
  • Scalable cloud-based architecture handling millions of samples enterprise-wide

Cons

  • Steep learning curve due to feature depth and customization needs
  • Enterprise pricing requires custom quotes, often prohibitive for small labs
  • Initial setup and data migration can be time-intensive

Best For

Large pharmaceutical, biotech, or academic labs requiring integrated, compliant sample management at scale.

Pricing

Custom enterprise subscription pricing (typically $50K+ annually per site); contact sales for quotes.

Visit Dotmaticsdotmatics.com
7
Labguru logo

Labguru

specialized

All-in-one ELN and LIMS for sample management, experiment tracking, and lab operations.

Overall Rating7.9/10
Features
8.2/10
Ease of Use
8.0/10
Value
7.5/10
Standout Feature

Direct linking of samples to ELN experiments for complete audit trails and reproducibility

Labguru is a cloud-based Electronic Lab Notebook (ELN) and lab management platform with robust sample and inventory management features. It enables tracking of samples and reagents from receipt to disposal, including barcode scanning, storage location mapping, and lifecycle history linked to experiments. The system supports customizable workflows, team collaboration, and integration with lab instruments for efficient sample handling in research environments.

Pros

  • Seamless integration of sample tracking with ELN for full experiment traceability
  • Barcode and RFID support for quick inventory management
  • Cloud-based access with mobile app for real-time updates

Cons

  • Less specialized for advanced LIMS needs compared to dedicated sample management tools
  • Initial customization and setup can be time-intensive
  • Pricing scales quickly for larger teams or advanced modules

Best For

Mid-sized biotech and research labs needing an all-in-one ELN with integrated sample management.

Pricing

Subscription starts at ~€99/user/month for basic plans; Pro and Enterprise tiers €149+/user/month with custom quotes.

Visit Labgurulabguru.com
8
QBench logo

QBench

specialized

Cloud-based LIMS for efficient sample accessioning, workflow orchestration, and reporting in testing labs.

Overall Rating8.3/10
Features
8.7/10
Ease of Use
8.0/10
Value
7.9/10
Standout Feature

No-code workflow builder allowing labs to create custom sample processing pipelines without programming

QBench is a cloud-based Laboratory Information Management System (LIMS) focused on sample management for scientific labs, enabling end-to-end tracking from receipt to disposal. It offers tools for workflow automation, inventory control, barcode/label printing, and instrument integrations to streamline lab operations. The platform supports compliance with standards like ISO 17025 and provides real-time reporting and analytics for efficient data management.

Pros

  • Comprehensive sample lifecycle tracking with barcode support
  • No-code workflow automation for custom processes
  • Strong integrations with lab instruments and ELNs

Cons

  • Initial configuration can be time-intensive
  • Pricing scales quickly for larger deployments
  • Mobile app lacks some desktop features

Best For

Mid-sized research, testing, or clinical labs needing scalable sample tracking and automation.

Pricing

Custom subscription pricing starting around $500/month for basic plans, scaling with users and modules.

Visit QBenchqbench.net
9
CloudLIMS logo

CloudLIMS

specialized

Secure SaaS LIMS for sample lifecycle management, compliance, and real-time collaboration.

Overall Rating8.2/10
Features
8.6/10
Ease of Use
7.7/10
Value
8.0/10
Standout Feature

Advanced cryogenic freezer management with real-time aliquot tracking and automated storage optimization

CloudLIMS is a cloud-based Laboratory Information Management System (LIMS) specializing in comprehensive sample management for life sciences, clinical, and biotech labs. It enables end-to-end sample tracking from accessioning and storage to analysis and disposal, with robust inventory management and automated workflows. The platform emphasizes regulatory compliance, such as FDA 21 CFR Part 11, and offers customizable dashboards for real-time visibility into lab operations.

Pros

  • Comprehensive sample lifecycle management with barcode/RFID tracking
  • Strong regulatory compliance tools including electronic signatures and audit trails
  • Scalable cloud architecture with customizable workflows and reporting

Cons

  • Steep learning curve for non-technical users due to extensive customization options
  • Pricing can be prohibitive for very small labs without volume discounts
  • Limited out-of-the-box integrations with some niche lab instruments

Best For

Mid-sized biotech, clinical, or research labs requiring robust, compliant sample tracking and inventory management.

Pricing

Quote-based pricing starting at around $500/month for basic plans, scaling with users, storage, and features (annual contracts typical).

Visit CloudLIMScloudlims.com
10
SciCord logo

SciCord

enterprise

Document-centric LIMS for sample management, batch records, and GMP compliance in manufacturing.

Overall Rating8.1/10
Features
8.5/10
Ease of Use
7.9/10
Value
7.7/10
Standout Feature

End-to-end sample chain-of-custody tracking with real-time status updates and automated notifications

SciCord is a cloud-based Laboratory Information Management System (LIMS) specialized in sample management for biotech, pharmaceutical, and research labs. It enables comprehensive tracking of samples throughout their lifecycle, from receipt and storage to processing, analysis, and disposal, with features for inventory control, barcode labeling, and automated workflows. The platform ensures regulatory compliance (e.g., 21 CFR Part 11) and integrates with lab instruments for seamless data flow.

Pros

  • Strong compliance tools with electronic signatures and audit trails
  • Flexible inventory and storage management with location tracking
  • Customizable workflows for diverse sample types

Cons

  • Pricing is quote-based and can be high for small labs
  • Limited native integrations with non-lab-specific tools
  • Mobile app functionality is basic compared to desktop

Best For

Mid-sized life sciences labs requiring robust, compliant sample tracking without extensive IT setup.

Pricing

Custom enterprise pricing; typically starts at $1,000/month for basic plans, scaling with users, storage, and modules (free demo available).

Visit SciCordscicord.com

Conclusion

The top 10 sample management software tools reviewed each bring unique strengths, but LabWare LIMS leads as the best choice for end-to-end lifecycle management, workflow automation, and regulatory compliance in labs. STARLIMS stands out for its flexibility across industries, while Thermo Scientific SampleManager excels in biopharma data integrity and instrument integration, making them strong alternatives for specific needs. Together, these tools cover diverse lab requirements, ensuring there’s a fit for every operation.

LabWare LIMS logo
Our Top Pick
LabWare LIMS

Explore LabWare LIMS today to streamline your sample management, boost efficiency, and meet compliance goals.